mi

Clinical Decision Support and Appropriateness of Antimicrobial Prescribing: A Randomized Trial

Interview with Matthew H. Samore, MD, author of Clinical Decision Support and Appropriateness of Antimicrobial Prescribing: A Randomized Trial, published in the November 9 issue of JAMA, the Journal of the American Medical Association. Summary points: 1. Repetitive use of a diagnostic and treatment algorithm to ingrain new prescribing habits was a valuable part of this practice change intervention. 2. Clinical decision support systems (CDSS) are feasibly implemented in practice settings that lack electronic medical records, including rural communities. 3. CDSS needs to be integrated with tools that save clinicians' time to be sustainable.




mi

Forty Years of A Piece of My Mind

Forty years ago, in 1980, Jimmy Carter was president. Pac-Man debuted. In medicine, smallpox was declared to be eradicated. Additionally, on May 9, 1980, A Piece of My Mind was inaugurated in JAMA. The first essay, “Tuna on Rye, 1984,” was written by then–senior editor Samuel Vaisrub under the pen name Sam Vee. He introduced the column with an editorial entitled “For the Peace of Your Mind.”




mi

For the Peace of Your Mind

We hasten to assure our readers that a piece of my mind...is not intended as a sounding board for peevish gripes, nit-picking beefs, or sundry assortments of righteous indignation, which are usually prefaced by an angry “let me give you a piece of my mind.” Nor is this section of The Journal meant to be a podium for pompous preachments and ex cathedra pronouncements. Nor again is it designed to be a forum for half-baked speculations and warmed-over hypotheses. Least of all is a piece of my mind envisaged as a jamboree of jokes and a shivaree of limericks.




mi

Miles Together—A Patient-Physician Journey

In this narrative medicine essay, a family physician shares the beginning and ending of a near 12-year journey with a patient, helping him reach sobriety that led to a full though short life and feeling humbled to have been so entrusted to travel with him.




mi

What Gets Measured Gets (Micro)managed

In this narrative medicine essay, an attending physician reflects on the evolution of the role of the attending physician from a supervisor in the background to a micromanaging supervisor to ensure that the proper steps are followed to meet the quality metrics in place in the current health system.




mi

A Death in the Family

In this narrative medicine essay, an anesthesia resident describes his feelings of loss and unease when a coresident is admitted as a patient and dies of an overdose of fentanyl; this article emphasizes the importance of prioritizing physician wellness programs to help avoid burnout and substance use disorder.




mi

How to Mentor Millennials

In this narrative medical essay, the authors present 3 scenarios exemplifying the collision between mentoring expectations among millennials and older generation faculty and proposes strategies to bridge generational divides and engage the next generation of physicians.




mi

Highly efficient electrochemiluminescence of ruthenium complex-functionalized CdS quantum dots and their analytical application

J. Mater. Chem. B, 2020, 8,3598-3605
DOI: 10.1039/C9TB02463H, Paper
Xiaofei Wang, Huiwen Liu, Honglan Qi, Qiang Gao, Chengxiao Zhang
Highly efficient electrochemiluminescence of ruthenium complex-functionalized CdS quantum dots via ECL resonance energy transfer (ECL-RET) and their analytical application.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Aggregation-induced emission luminogens for RONS sensing

J. Mater. Chem. B, 2020, 8,3357-3370
DOI: 10.1039/C9TB02310K, Review Article
Jun Dai, Chong Duan, Yu Huang, Xiaoding Lou, Fan Xia, Shixuan Wang
The development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Graphene–nucleic acid biointerface-engineered biosensors with tunable dynamic range

J. Mater. Chem. B, 2020, 8,3623-3630
DOI: 10.1039/C9TB02388G, Paper
Zhifeng Zhao, Hao Yang, Wenyue Zhao, Sha Deng, Kaixiang Zhang, Ruijie Deng, Qiang He, Hong Gao, Jinghong Li
Programmed biosensors with tunable quantification range and higher specificity have been constructed by engineering graphene–nucleic acid biointerfaces.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Ti3C2Tx MXene-derived TiO2/C-QDs as oxidase mimics for the efficient diagnosis of glutathione in human serum

J. Mater. Chem. B, 2020, 8,3513-3518
DOI: 10.1039/C9TB02478F, Communication
Zhaoyong Jin, Gengfang Xu, Yusheng Niu, Xiaoteng Ding, Yaqian Han, Wenhan Kong, Yanfeng Fang, Haitao Niu, Yuanhong Xu
A Ti3C2Tx MXene-derived TiO2/C-QD oxidase mimic was developed and used for the efficient diagnosis of glutathione in human serum.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Recent advances of tissue-interfaced chemical biosensors

J. Mater. Chem. B, 2020, 8,3371-3381
DOI: 10.1039/C9TB02476J, Review Article
Chuanrui Chen, Yue Guo, Peining Chen, Huisheng Peng
This review discusses recent advances of tissue interfaced chemical biosensors, highlights current challenges and gives an outlook on future possibilities.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Stretchable gold fiber-based wearable electrochemical sensor toward pH monitoring

J. Mater. Chem. B, 2020, 8,3655-3660
DOI: 10.1039/C9TB02477H, Paper
Ren Wang, Qingfeng Zhai, Yunmeng Zhao, Tiance An, Shu Gong, Zhirui Guo, QianQian Shi, Zijun Yong, Wenlong Cheng
A stretchable gold fiber-based wearable electrochemical pH two-electrodes sensing system for human health monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Nucleoside-based fluorescent carbon dots for discrimination of metal ions

J. Mater. Chem. B, 2020, 8,3640-3646
DOI: 10.1039/C9TB02758K, Paper
Tieli Zhou, Jinyi Zhang, Biwu Liu, Shihong Wu, Peng Wu, Juewen Liu
Using nucleosides and citrate as starting materials, a series of fluorescent carbon dots were synthesized showing different quenching properties by metal ions for their detection by a sensor array.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

J. Mater. Chem. B, 2020, 8,3606-3615
DOI: 10.1039/C9TB02439E, Paper
Iene Rutten, Devin Daems, Jeroen Lammertyn
Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Structurally coloured contact lens sensor for point-of-care ophthalmic health monitoring

J. Mater. Chem. B, 2020, 8,3519-3526
DOI: 10.1039/C9TB02389E, Paper
Yunlong Wang, Qilong Zhao, Xuemin Du
A structurally coloured contact lens sensor has been developed for point-of-care diagnosis of eye diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Wearable biochemical sensors for human health monitoring: sensing materials and manufacturing technologies

J. Mater. Chem. B, 2020, 8,3423-3436
DOI: 10.1039/C9TB02474C, Review Article
Guanglei Li, Dan Wen
Recent achievements and challenges in materials and manufacturing technologies of sensing electrodes in wearable biosensors have been highlighted.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

J. Mater. Chem. B, 2020, 8,3192-3212
DOI: 10.1039/C9TB02578B, Review Article
Rashaad A. Husain, Snigdha Roy Barman, Subhodeep Chatterjee, Imran Khan, Zong-Hong Lin
An overview of enhancement strategies for highly sensitive ECL-based sensing of bioanalytes enabling early detection of cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

A perylenetetracarboxylic dianhydride and aniline-assembled supramolecular nanomaterial with multi-color electrochemiluminescence for a highly sensitive label-free immunoassay

J. Mater. Chem. B, 2020, 8,3676-3682
DOI: 10.1039/C9TB02368B, Paper
Wei Zhang, Yue Song, Yunyun Wang, Shuijian He, Lei Shang, Rongna Ma, Liping Jia, Huaisheng Wang
A novel multi-color ECL nanomaterial assembled from 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) and aniline (An) was used for highly sensitive label-free CEA detection.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

A general strategy for designing NIR-II emissive silk for the in vivo monitoring of an implanted stent model beyond 1500 nm

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02685A, Paper
Zhiming Deng, Junqing Huang, Zhenluan Xue, Mingyang Jiang, Youbin Li, Songjun Zeng
The NIR-II emissive silk is explored by a general feeding strategy for NIR-II imaging guided in situ monitoring of the implanted biological stent model made from silk.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Recent progress of SERS optical nanosensors for miRNA analysis

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00280A, Review Article
Yudie Sun, lin shi, Lan Mi, Ruiyan Guo, Tao Li
This review focus on emerging applications of surface-enhanced Raman spectroscopy (SERS) optical nanosensors for miRNA analysis, in which the key enhancement factors of SERS signal, i.e. SERS-active substrates, SERS nanoprobes...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Rapidly dissolving microneedle patch for synergistic gene and photothermal therapy of subcutaneous tumor

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00105H, Paper
Qinan Xu, Xinfang Li, Peng Zhang, Youxiang Wang
Synergistic gene and photothermal therapy conducted by p53 DNA/IR820 MN patch may be a promising strategy for subcutaneous tumor treatments.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00874E, Paper
Haijie Han, Qichuan Yin, Xiajing Tang, Xiaoning Yu, Qiang Gao, Yelei Tang, Andrzej Grzybowski, Ke Yao, Jian Ji, Xingchao Shentu
Corneal neovascularization (CNV) is one of the leading risk factors for vision loss. Anti-angiogenic drugs can theoretically be extended to the treatment of CNV. However, the application of these drugs...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Multi-Stimuli Responsive Polymeric Prodrug Micelles for Combined Chemotherapy and Photodynamic Therapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00539H, Paper
Cheng Hu, Weihua Zhuang, Tao Yu, Liang Chen, Zhen Liang, Gaocan Li, Yunbing Wang
Nowadays, cancer therapy faces severe challenges on boosting therapeutic efficiency and reducing the side effects of drugs. To overcome these challenges, herein multifunctional polymeric prodrug micelles with combining chemotherapy and...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Biomimetic Immunomagnetic Gold Hybrid Nanoparticles Coupled with Inductively Coupled Plasma Mass Spectrometry for the Detection of Circulating Tumor Cells

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00403K, Paper
Zhimin Chang, Hang Zhou, Chao Yang, Rui Zhang, Qiannan You, Ruhong Yan, Li Li, Mingfeng Ge, Yuguo Tang, Wen-fei Dong, Zheng Wang
Immunomagnetic beads are important tools for the isolation and detection of circulating tumor cells (CTCs). However, the current immunomagnetic bead technique provides poor CTC separation purity due to nonspecific binding...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Fluorinated porphyrin-based theranostics for dual imaging and chemo-photodynamic therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00083C, Paper
Huaibin Zhang, Shaowei Bo, Kai Zeng, Jie Wang, Yu Li, Zhigang Yang, Xin Zhou, Shizhen Chen, Zhong-Xing Jiang
A modular strategy facilitates the convenient and standardized preparation of multifunctional theranostics for cancer therapy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Bioinspired polydopamine nanoparticles: synthesis, nanomechanical properties, and efficient PEGylation strategy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02769F, Paper
Islam Zmerli, Jean-Philippe Michel, Ali Makky
We established tightly controlled experimental conditions to synthesize polydopamine nanoparticles with well-defined and reproducible physicochemical properties such as size, yield and nanomechanics.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Aqueous surface gels as low friction interfaces to mitigate implant-associated inflammation

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00582G, Perspective
Allison L. Chau, Jonah Rosas, George D. Degen, Lisa K. Månsson, Jonathan Chen, Eric Valois, Angela A. Pitenis
Soft implant surfaces should be designed with an eye toward natural, healthy biointerfaces, which use high water content aqueous gel gradients to reduce contact pressures and frictional shear stresses and thus reduce inflammation and discomfort.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Controllable hydrogen bonded self-association for the formation of multifunctional antimicrobial materials

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00875C, Paper
Lisa White, Jessica E. Boles, Nyasha Allen, Luke Alesbrook, J. Mark Sutton, Charlotte Hind, Kira Hilton, Laura R. Blackholly, Rebecca Ellaby, George Williams, Daniel P Mulvihill, Jennifer Ruth Hiscock
SSAs are a class of Supramolecular Self-associating Amphiphilic salt, the anionic component of which contains a covalently bound hydrogen bond donor-acceptor motif. This results in a monomeric unit which can...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Unique Sequence-Dependent Properties of Trinucleotide Repeat Monolayers: Electrochemical, Electrical, and Topographic Characterization

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00507J, Paper
Narges Asefifeyzabadi, Motahareh Taki, Madison Funneman, Tingjie Song, Mohtashim Hassan Shamsi
Trinucleotide repeat (TNR) sequences widely exist in nature and their overgrowth is associated with two dozen neurodegenerative diseases in humans. These sequences have unique helical flexibility which affects their biophysical...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Progress in biomimetic leverages for marine antifouling using nanocomposite coatings

J. Mater. Chem. B, 2020, 8,3701-3732
DOI: 10.1039/C9TB02119A, Review Article
Mohamed S. Selim, Sherif A. El-Safty, Mohamed A. Shenashen, Shimaa A. Higazy, Ahmed Elmarakbi
Because of the environmental and economic casualties of biofouling on maritime navigation, modern studies have been devoted toward formulating advanced nanoscale composites in the controlled development of effective marine antifouling self-cleaning surfaces.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy

J. Mater. Chem. B, 2020, 8,3772-3788
DOI: 10.1039/D0TB00262C, Review Article
Yu Huang, Feng Qiu, Rongjun Chen, Deyue Yan, Xinyuan Zhu
In this Review, recent advances in fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy are described, and the current challenges and perspectives in this emerging field are also discussed.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Macrocyclic polyamine [12]aneN3 modified triphenylamine-pyrazine derivatives as efficient non-viral gene vectors with AIE and two-photon imaging properties

J. Mater. Chem. B, 2020, 8,3869-3879
DOI: 10.1039/D0TB00321B, Paper
Le-Le Ma, Ming-Xuan Liu, Xu-Ying Liu, Wan Sun, Zhong-Lin Lu, Yong-Guang Gao, Lan He
[12]aneN3 modified triphenylamine-pyrazines as non-viral gene vectors with AIE and two-photon imaging properties.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

“Watson–Crick GC”-inspired supramolecular nanodrug of methotrexate and 5-fluorouracil for tumor microenvironment-activatable self-recognizing synergistic chemotherapy

J. Mater. Chem. B, 2020, 8,3829-3841
DOI: 10.1039/D0TB00468E, Paper
Meijin Chen, Shiduan Chen, Fukai Zhu, Fanfan Wang, Haina Tian, Zhongxiong Fan, Sunkui Ke, Zhenqing Hou, Yang Li
The “Watson–Crick G≡C”-inspired carrier-free nanodrug have excellent tumor microenvironment-triggered active self-targeting ability and enhanced synergistic chemotherapeutic effects.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity

J. Mater. Chem. B, 2020, 8,3939-3948
DOI: 10.1039/D0TB00327A, Paper
Boya Zhang, Shiyu Wan, Xinyu Peng, Mingying Zhao, Sai Li, Yuji Pu, Bin He
A nano-assembly of pH-sensitive doxorubicin prodrug and human serum albumin shows tumor pH-responsive aggregation, enhanced tumor retention and reduced cytotoxicity.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Ternary hydrogels with tunable mechanical and self-healing properties based on the synergistic effects of multiple dynamic  bonds

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02885D, Paper
Kun Li, Jingxi Wang, Ping Li, Yubo Fan
Ternary hydrogels with tunable mechanical properties were prepared based on the synergistic effects of hydrogen bonds and imine bonds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Boron-based nanosheets for combined cancer photothermal and photodynamic therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00070A, Paper
Yong Kang, Xiaoyuan Ji, Zhengjun Li, Zhiguo Su, Songping Zhang
Tumor phototherapy is of great significance for the expansion and advancement of cancer treatment methods.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Discrimination of cysteamine from mercapto amino acids through isoelectric point-mediated surface ligand exchange of β-cyclodextrin-modified gold nanoparticles

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00462F, Paper
Quanbao Ma, Xun Fang, Junting Zhang, Lili Zhu, Xiabing Rao, Qi Lu, Zhijun Sun, Huan Yu, Qunlin Zhang
A pI-mediated R6G-β-CD@AuNPs system was designed for the first time for the discrimination of CA from GSH/Cys/Hcy in human serum samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00357C, Paper
Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Lili Zhu, Jianxiang Shi, Wenxue Tang, Wang Ma, Hong Zong, Wei Jiang
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer tissues and inefficient reactive oxygen species (ROS) production.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

A bio-inspired injectable hydrogel as a cell platform for real-time glycaemic regulation

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00561D, Paper
Yu Zhang, Jun Yang, Jun Zhang, Shuangwen Li, Lisi Zheng, Yanlong Zhang, Huipeng Meng, Xinge Zhang, Zhongming Wu
A bio-inspired injectable hydrogel as a cell platform for real time glycemic regulation by mimicking the function of native islet β cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Regulation of cell binding and entry by DNA origami mediated spatial distribution of aptamers

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00663G, Communication
Ke Liu, Cong Xu, Jinyao Liu
Customizing the spatial distribution of aptamers on DNA origami nanoboxes can regulate the internalization and proliferation of cancer cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

Hydrogels toughened by biominerals as energy-dissipative sacrificial bonds

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00833H, Communication
Kazuki Fukao, Kazuki Tanaka, Ryuji Kiyama, Takayuki Nonoyama, Jian Ping Gong
Inspired by bone tissues, hydrogels toughened by hydroxyapatite (HAp) working as energy-dissipative sacrifical bonds is created. The contribution of dissipated energy from HAp mineral was over 500 % higher than...
The content of this RSS Feed (c) The Royal Society of Chemistry




mi

The interplay of influence : news, advertising, politics, and the Internet / Kathleen Hall Jamieson, Karlyn Kohrs Campbell

Jamieson, Kathleen Hall




mi

The Johns Hopkins guide to digital media / edited by Marie-Laure Ryan, Lori Emerson, and Benjamin J. Robertson




mi

The news gap : when the information preferences of the media and the public diverge / Pablo Javier Boczkowski and Eugenia Mitchelstein

Boczkowski, Pablo J




mi

Teaching academic writing : a toolkit for higher education / Caroline Coffin ... [et al.]




mi

Inconsistencies in the regulation of the media / House of Representatives Standing Committee on Transport, Communications and Infrastructure

Australia. Parliament. House of Representatives. Standing Committee on Transport, Communications and Infrastructure




mi

Post-1990 documentary : reconfiguring independence / edited by Camille Deprez and Judith Pernin




mi

Advancing the story : journalism in a multimedia world / Debora Halpern Wenger, University of Mississippi, Deborah Potter, Newslab

Wenger, Debora Halpern




mi

Classrooms of possibility : supporting at-risk EAL students / edited by Jennifer Hammond and Jennifer Miller