rc Trump lies, sows division, and wastes recovery resources as Americans suffer By boingboing.net Published On :: Tue, 01 Oct 2024 15:39:52 +0000 Adjudicated rapist and convicted felon Donald Trump chose to politicize the Federal response to Hurricane Helene, demonstrating little concern about the actual devastation. Responsible leaders who care about the people they govern do not leap into every photo opportunity they can find. — Read the rest The post Trump lies, sows division, and wastes recovery resources as Americans suffer appeared first on Boing Boing. Full Article Post politics
rc March Madness in High Def By communicationtransformation.blogspot.com Published On :: Mon, 23 Mar 2009 12:39:00 +0000 Ryan Lawler notes in his Contentinople blog that CBS's high definition stream of the NCAA men's basketball tournament has been a great success.CBS Sports reported that traffic to its NCAA March Madness on Demand site on the first day of the tourney increased 56 percent year-over-year, to 2.7 million unique users yesterday from 1.75 million uniques a year ago. If there is a conclusion to be drawn, I do not think it is that internet video can or should compete with television. In this case, I believe the draw is a combination of the fact that watching television on Thursday afternoon is not an option for people with a day job, and that there are many games going on simultaneously and CBS television does not always cut to the game that the individual user wants to see.I think the focus should be on the success of delivering a high quality video experience to a large audience, many of whom were at work. This is just another step in the direction of enterprise video becoming an essential element of the workplace experience. Full Article
rc Lawfare Freeze: Judge Merchan Delays Decision On Trump Sentencing By conservativefiringline.com Published On :: Wed, 13 Nov 2024 00:15:30 +0000 The following article, Lawfare Freeze: Judge Merchan Delays Decision On Trump Sentencing, was first published on Conservative Firing Line. BREAKING: Justice Merchan has granted a request from prosecutions/defense to pause deadlines — including Trump's sentencing date — while they consider the effect of his election as president. https://t.co/LaeJlAyTDi pic.twitter.com/SAHVbo3HbG — Kyle Cheney (@kyledcheney) November 12, 2024 Developing … * * * Content created by the WND News Center is available for re-publication without charge … Continue reading Lawfare Freeze: Judge Merchan Delays Decision On Trump Sentencing ... Full Article Politics case delay lawfare Merchan Trump
rc Forty-Seven Percent Of Harris Voters Believe Trump Will Not Be A Legitimate President; 54 Percent Want To Leave The Country By conservativefiringline.com Published On :: Wed, 13 Nov 2024 01:15:35 +0000 The following article, Forty-Seven Percent Of Harris Voters Believe Trump Will Not Be A Legitimate President; 54 Percent Want To Leave The Country, was first published on Conservative Firing Line. I really wish that everyone would just calm down. Emotions always run high immediately after an election, but what we are witnessing this time around is truly frightening. We live at a time when people feel free to express their deepest, darkest emotions on social media, and right now “freak out video” after “freak out … Continue reading Forty-Seven Percent Of Harris Voters Believe Trump Will Not Be A Legitimate President; 54 Percent Want To Leave The Country ... Full Article Opinion Politics country Harris leave liberals Trump voters
rc What’s SearchGPT Really About? Moving Past the Training Data Dilemma. By battellemedia.com Published On :: Fri, 26 Jul 2024 14:18:26 +0000 This morning we awoke to one story dominating the tech news landscape: OpenAI is “expanding into search,” launching SearchGPT, a prototype that appears to be a direct competitor to Google (and Bing and Perplexity, not that they really matter). But despite the voluminous coverage, my initial take is that once the hype cycle passes – … Continue reading "What’s SearchGPT Really About? Moving Past the Training Data Dilemma." Full Article AI Future of Search Internet Big Five Joints After Midnight & Rants Media/Tech Business Models ai media publishing search
rc From the Archive: Tech Must Get Over Its Superman Complex, Or We’re All Screwed By battellemedia.com Published On :: Tue, 06 Aug 2024 01:35:11 +0000 Five years ago I was posting a lot to a publication called NewCo Shift, which is now offline. I got ahold of the archives, and found this review, which hasn’t lost any of its relevance – in fact, it kind of reads like it was written last week. Everyone in tech loves Yuval Noah Harari. … Continue reading "From the Archive: Tech Must Get Over Its Superman Complex, Or We’re All Screwed" Full Article AI Book Related Internet Big Five Policy
rc Trump to Pick Senator Marco Rubio for Crucial Cabinet Position: Report By www.westernjournal.com Published On :: Tue, 12 Nov 2024 12:33:39 +0000 President-elect Donald Trump is expected to nominate Florida Sen. Marco Rubio as his secretary of state, reports late Monday indicate. According to The Wall Street Journal, while the nomination isn’t […] The post Trump to Pick Senator Marco Rubio for Crucial Cabinet Position: Report appeared first on The Western Journal. Full Article News Donald Trump Federal government Marco Rubio Trump administration U.S. News
rc Judge Juan Merchan Grants Request from Trump's Legal Team and DA in NY Hush Money Case By www.westernjournal.com Published On :: Tue, 12 Nov 2024 19:24:49 +0000 New York Judge Juan Merchan — who is overseeing President-elect Donald Trump’s business records case — agreed to freeze the case until Nov. 19. There was to be a hearing […] The post Judge Juan Merchan Grants Request from Trump's Legal Team and DA in NY Hush Money Case appeared first on The Western Journal. Full Article News 2024 election Donald Trump New York state Prosecuting Trump
rc Sport | Marco Jansen hopes for better showing against spin as T20 series takes Highveld turn By www.news24.com Published On :: Tuesday Nov 12 2024 15:29:43 Proteas all-rounder Marco Jansen, while acknowledging that spin has been a challenge for them in the ongoing T20 series against India, reckons things could be a bit different for Wednesday's third T20 in Centurion. Full Article
rc Newsroom: Carvana Now Among Top 10 US Retailers by Ecommerce Sales By www.emarketer.com Published On :: Wed, 23 Feb 2022 04:01:00 GMT Carvana is America’s fastest-growing e-tailer   February 23, 2022 (New York, NY) – Americans have taken to buying cars online, so much so that ecommerce car dealer Carvana is now […] Full Article
rc Newsroom: US Ecommerce Will Cross $1 Trillion in 2022 By www.emarketer.com Published On :: Tue, 14 Jun 2022 04:01:00 GMT Amazon’s share declines for first time; Apple surpasses eBay in online sales June 14, 2022 (New York, NY) – This year will mark a major US retail milestone, as ecommerce […] Full Article
rc Commentary: Second Assassination Attempt Forces New Reckoning for Trump, Secret Service By deneenborelli.com Published On :: Tue, 17 Sep 2024 14:23:52 +0000 Commentary by Susan Crabtree and Philip Wegmann originally published by The second assassination attempt against former President Donald Trump while he was golfing at one of his Florida courses on Sunday is forcing the United States Secret Service to further tighten security around the Republican presidential nominee and to reevaluate just how much Trump should … Full Article Commentaries News
rc Russia and China in Antarctica: Implications for the Five Eyes By www.chathamhouse.org Published On :: Fri, 02 Dec 2022 14:17:13 +0000 Russia and China in Antarctica: Implications for the Five Eyes 15 December 2022 — 11:00AM TO 12:00PM Anonymous (not verified) 2 December 2022 Online This event explores Russia’s and China’s postions on the Antarctic and offers a critical assessment of their actions in the region. Ever since the 1959 Antarctic Treaty System (ATS), signed at the height of Cold War, Antarctica has remained a demilitarized continent. Today, even though the ATS is not in immediate danger of collapse, Antarctica and the Southern Ocean are no longer insulated from wider geopolitical tension, with China and Russia posing challenges to regional governance. This event also discusses key recommendations for the Five Eyes regarding Russian and Chinese current and future efforts at undermining the ATS and Antarctic governance. The discussion is informed by Mathieu Boulègue’s paper ‘Russia and China in Antarctica and the Southern Ocean: Implications for the Five Eyes’ published by the Sea Power Centre of the Royal Australian Navy. Full Article
rc A world in transition and the future of the global workforce By www.chathamhouse.org Published On :: Thu, 22 Aug 2024 12:12:13 +0000 A world in transition and the future of the global workforce 15 October 2024 — 9:00AM TO 10:00AM Anonymous (not verified) 22 August 2024 Chatham House and Online How are migration and global megatrends shaping international labour? As the fallout of 2024’s ‘Election Super-Year’ becomes clearer, international policymakers and business leaders must now equip themselves to face the challenges and opportunities of the three key transitions that will dominate the next few decades: the journey toward a greener and healthier world; the transition to a more technologically adept society; and the development of a secure and productive economy for all.The adaption and evolution of the global workforce is an essential component of all three of these transitions and therefore a prescient analysis of how migration, workforce policies and modern technology trends will impact this ecosystem is essential.Upskilling the workforce will no doubt remain a key focus for stakeholders. But the question remains, how do these plans move beyond the ‘ideas-phase’ and become policies that will keep pace in the fast-paced, modern and digital workplace?It may prove harder than ever for these ideas to come to fruition, with the rise of populist and nationalist political thinking fragmenting the balance between local and international labour. Indeed, this often leads to reduced attractiveness of skilled foreign labour in domestic markets.This puts global business in a very powerful position though, as companies can play an important role in readdressing these narratives, shaping the future of workforce policies and using examples of best practice to improve access, mobility and ultimately economic productivity, for the benefit of all.Through this event, in partnership with EY, the panel analyses how migration, skills development agendas and global megatrends, such as technology, sustainability and the global economy, will shape developments in the years to come.A networking breakfast precedes this event, served between 0800 and 0900 BST.Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
rc Making the circular economy work for global development: how the UN Summit of the Future can deliver By www.chathamhouse.org Published On :: Thu, 05 Sep 2024 09:02:13 +0000 Making the circular economy work for global development: how the UN Summit of the Future can deliver 23 September 2024 — 6:15PM TO 9:00PM Anonymous (not verified) 5 September 2024 Online This policy roundtable focusses on how to advance implementation of a global approach and collaboration to an inclusive circular economy for an updated post-2030 SDG framework. As the world looks beyond the Sustainable Development Goals (SDGs) towards the post-2030 era, integrating the principles of the circular economy into the future global development agenda becomes imperative. A new Chatham House research paper about the role of the circular economy for the SDGs and their possible extension into the post-2030 development agenda will be launched in September 2024 during the UN Summit of the Future and the New York Climate Week. The paper outlines the rationale for the integration of circular economy goals into for the next crucial phase of international development and how to meet net-zero 2050 targets. It provides actionable recommendations on international cooperation mechanisms for policymakers and stakeholders at the UN Summit for the Future in 2024 and beyond.The aim of the roundtable is to bring together stakeholders and leaders from intergovernmental organisations, business, governments and civil society. The focus of the roundtable meeting is: Reflections on the Summit of the Future and the role of circularity for an updated post-2030 SDG framework.Discussion on key aspects of the institutional arrangements and international coordination that are needed for a globally coordinated approach to achieve an inclusive circular economy that supports SDG implementation. Development of joint strategies on how to advance implementation of a global approach and collaboration to an inclusive circular economy as a follow-up from the Summit of the Future.The objective is to emerge from the roundtable with a clearer roadmap for translating the recommendations for international coordination into concrete actions, with a shared commitment to driving meaningful change on the international level.The event is co-hosted by Chatham House and partners from the Global Circular Economy Roadmap initiative including the African Circular Economy Network, the African Development Bank, Circular Change, Circular Innovation Lab, Circle Economy, EU CE Stakeholder Platform, Hanns Seidel Foundation, Institute of Global Environmental Strategies, Sitra, UNIDO, World Business Council on Sustainable Development, World Economic Forum and the Wyss Academy for Nature.Further background information is available on the initiative website.More speakers to be announced. Full Article
rc Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity [Methods and Resources] By www.jbc.org Published On :: 2020-12-04T00:06:05-08:00 The cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane anion channel that plays a key role in controlling transepithelial fluid movement. Excessive activation results in intestinal fluid loss during secretory diarrheas, whereas CFTR mutations underlie cystic fibrosis (CF). Anion permeability depends both on how well CFTR channels work (permeation/gating) and on how many are present at the membrane. Recently, treatments with two drug classes targeting CFTR—one boosting ion-channel function (potentiators) and the other increasing plasma membrane density (correctors)—have provided significant health benefits to CF patients. Here, we present an image-based fluorescence assay that can rapidly and simultaneously estimate both CFTR ion-channel function and the protein's proximity to the membrane. We monitor F508del-CFTR, the most common CF-causing variant, and confirm rescue by low temperature, CFTR-targeting drugs and second-site revertant mutation R1070W. In addition, we characterize a panel of 62 CF-causing mutations. Our measurements correlate well with published data (electrophysiology and biochemistry), further confirming validity of the assay. Finally, we profile effects of acute treatment with approved potentiator drug VX-770 on the rare-mutation panel. Mapping the potentiation profile on CFTR structures raises mechanistic hypotheses on drug action, suggesting that VX-770 might allow an open-channel conformation with an alternative arrangement of domain interfaces. The assay is a valuable tool for investigation of CFTR molecular mechanisms, allowing accurate inferences on gating/permeation. In addition, by providing a two-dimensional characterization of the CFTR protein, it could better inform development of single-drug and precision therapies addressing the root cause of CF disease. Full Article
rc Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes [Enzymology] By www.jbc.org Published On :: 2020-12-04T00:06:06-08:00 G protein–coupled receptors (GPCRs) initiate signaling cascades via G-proteins and beta-arrestins (βarr). βarr-dependent actions begin with recruitment of βarr to the phosphorylated receptor tail and are followed by engagement with the receptor core. βarrs are known to act as adaptor proteins binding receptors and various effectors, but it is unclear whether in addition to the scaffolding role βarrs can allosterically activate their downstream targets. Here we demonstrate the direct allosteric activation of proto-oncogene kinase Src by GPCR–βarr complexes in vitro and establish the conformational basis of the activation. Whereas free βarr1 had no effect on Src activity, βarr1 in complex with M2 muscarinic or β2-adrenergic receptors reconstituted in lipid nanodiscs activate Src by reducing the lag phase in Src autophosphorylation. Interestingly, receptor–βarr1 complexes formed with a βarr1 mutant, in which the finger-loop, required to interact with the receptor core, has been deleted, fully retain the ability to activate Src. Similarly, βarr1 in complex with only a phosphorylated C-terminal tail of the vasopressin 2 receptor activates Src as efficiently as GPCR–βarr complexes. In contrast, βarr1 and chimeric M2 receptor with nonphosphorylated C-terminal tail failed to activate Src. Taken together, these data demonstrate that the phosphorylated GPCR tail interaction with βarr1 is necessary and sufficient to empower it to allosterically activate Src. Our findings may have implications for understanding more broadly the mechanisms of allosteric activation of downstream targets by βarrs. Full Article
rc A Digital India Must Embrace the Circular Economy By www.chathamhouse.org Published On :: Mon, 15 Jan 2018 10:48:13 +0000 A Digital India Must Embrace the Circular Economy Expert comment sysadmin 15 January 2018 A growing amount of e-waste should draw attention to the broader sustainability of a digital society. — Workers dismantle old computers at an e-waste recycling factory near Bangalore. Photo: Getty Images. The latest Global E-Waste Monitor places India as one of the highest contributors to global e-waste, generating over 2 million metric tonnes in 2016. Posing serious health and environmental risks, growing e-waste represents the hidden cost of increasingly digital lives in an information society. With just 33 per cent of the population owning a smart phone, India already has the second largest number of smart phone users in the world, nearly 4 times that of the United States. The amount of e-waste generated will exponentially increase in the coming decade as the cost of consumer electronics decline, middle-class incomes rise, and the frequency at which devices are discarded increases. As governance instruments are increasingly digitized and industry re-repositions itself to leverage Industry 4.0 solutions, the generation of e-waste will become a byproduct of institutional choices rather than consumer consumption and behaviour alone. India is already a leader in the management and recycling of e-waste. But over 90 per cent is managed in the unorganized sector by small businesses and individual entrepreneurs, typically from low-income marginalized communities, and often women. E-waste contains various toxic substances such as mercury and lead, prolonged exposure to which can lead to major health problems. Almost 80 per cent of e-waste workers in India suffer from respiratory ailments due to improper standards and nearly 500,000 children are engaged in e-waste collection without adequate protection and safeguards. The bulk of the dirty and dangerous work supporting India’s march towards an increasingly digital society is done by those who have the least access to technology gains. Government regulations for the management of e-waste, on the other hand, are becoming more relaxed, presumably as a result of industry pressure. To streamline e-waste management, the government notified Electronic Waste Rules in 2011, based on the concept of extended producer responsibility (EPR). EPR makes manufacturers of electronic products responsible for the end-of-life management of their products, including setting up collection centres. By shifting the burden to manufacturers, the EPR framework, in theory, creates incentives for more environmentally friendly design. But the impact of EPR rules on manufacturers has been minimal, at best. The recently released Draft Notification (2017) by the Ministry of Environment, Forest and Climate Change further relaxes the EPR rule by reducing the e-waste collection targets for industries. While the efficiency and productivity gains of Digital India are to be welcomed, growing e-waste should draw attention to the broader sustainability of a digital society. Data centres, for example, are one the largest contributors to global warming, contributing a similar amount to global greenhouse emissions as the aviation industry. This amount is expected to triple in the next decade. In many ways, the sustainability challenge is a ‘wicked problem’ – where possible solutions create a new set of additional challenges and the choice between available alternatives is largely about competing values. For example, data centres powered by renewable sources of energy such as solar provide a greener alternative, but will also create new forms of e-waste in the form of photovoltaic cells and panels. An unverified estimate suggests that India’s projected solar capacity of 100 gigawatts by 2022 will create 7.76 million tonnes of e-waste. Without adequate and preemptive consideration of how this waste should be disposed and recycled, renewable energy solutions can create new negative externalities. For Digital India to be sustainable, we need to develop anticipatory knowledge for preemptive solutions. It is an opportune moment to think of the broader architecture of a digital society, one that avoids getting locked into unsustainable models of production and consumption, as is the case with many industrialized economies. The argument that such considerations are premature for India, given high levels of poverty and unemployment, are misplaced. Enquiries into the sustainability of Digital India are no less urgent than the need for sustained job-creating economic growth. These issues should not be addressed in a sequential or linear manner, but in parallel, or else we will be only partially aware of available choices and their consequences, creating new forms of technological and economic lock-ins. The value-based choice demanded by the ‘wicked problem’ at hand is one that embraces the idea of a circular economy — one that departs from the linear economic growth model predicated on ‘take, make, dispose’ to embrace a growth model based on creating closed loops of production, consumption and re-use. A circular economy model is built on the idea of designing out waste and pollution; keeping products and materials in use; and regenerating natural systems. In many ways, India is already a leader in the circular economy. Alongside, the management of e-waste and other forms of recycling, high levels of repair and reuse are distinctly observable. A number of reports note that the informal waste management sector in India works better than systems in many industrialized economies. A circular economy vision for Digital India would include organizing informal waste management systems, including safety and social protection initiatives for workers; revising and tightening existent e-waste rules for increased accountability by manufacturers both in terms of durable design and responsible disposal; green data centres; and building future smart cities with a view towards energy and water efficiency, among others. A recent report by the Ellen McArthur Foundation and the World Economic Forum also estimates that a circular economy path to development could bring India annual benefits of $624 billion by 2050. Greenhouse gas emissions could also be 44 per cent lower in 2050, compared with current development path. Unsurprisingly, Nordic countries are leading the way in promoting the idea of a circular economy. Sweden recently announced tax breaks for repair related activities and Finland hosted the first global conference on the circular economy earlier this year. The circular economy provides an opportunity for India to capitalize and leverage an already existing culture of circular activities, and promote it as a policy agenda that will create new forms of employment while facilitating sustainable environmental management. This article was originally published in the Indian Express. Full Article
rc The Indo-Pacific: Geostrategic Perspectives until 2024 – Japanese perceptions By www.chathamhouse.org Published On :: Mon, 22 Mar 2021 14:50:49 +0000 The Indo-Pacific: Geostrategic Perspectives until 2024 – Japanese perceptions 24 February 2020 — 9:00AM TO 1:00PM Anonymous (not verified) 22 March 2021 Chatham House The roundtable brought together stakeholders within Japan’s strategic and policymaking communities to explore Japanese perceptions of evolving strategic shifts in the Indo-Pacific until 2024. The roundtable took place in Tokyo and was organized in partnership with the Indo-Pacific Studies Group. The report below contains a summary of the discussions and an essay by Hiroki Sekine, Visiting Fellow, Asia-Pacific Programme, Chatham House. Read a summary and essay Full Article
rc The interconnected impacts of the Iraq war By www.chathamhouse.org Published On :: Wed, 22 Mar 2023 15:43:28 +0000 The interconnected impacts of the Iraq war Expert comment LJefferson 22 March 2023 Relying on weak intelligence for invading Iraq has had a negative impact on US and UK credibility with several consequences that persist to this day. 20 years on from the fateful decision to invade Iraq, it is generally accepted that the US and UK governments overstated the evidence available for them to justify military action. The central claim to defend invading Iraq was that the country had continued its illicit nuclear weapons programme and had retained illegal stockpiles of biological and chemical weapons. None of these claims supported an imminent threat justification nor could any hidden caches of WMD be found by the US Iraq Survey Group after the invasion. In the US, President George W. Bush and Vice President Dick Cheney hinted at additional evidence which could not be shared publicly to suggest that if only people knew what the government knew, they would agree that Iraq posed a significant threat to the West and needed to be disarmed. In the UK, the Blair government acted similarly, focusing on a narrow interpretation of the evidence provided by the intelligence services and ignoring many of the dire warnings offered by academics and other experts. The Chilcot Inquiry found that the Blair government greatly exaggerated the threat Iraq posed to the UK, and that government arguments were based on the prime minister’s personal beliefs, as well as his promise to President Bush to support the US invasion. Relying on inadequate information and a biased analysis for invading Iraq has had a negative impact on US and UK credibility in the international security policy environment and domestically with ramifications that persist to this day. Impacts on soft power and trust The invasion had an impact on US and UK soft power due to negative perceptions of the decision to go to war and the competence of the UK and US: public opinion polling by the Pew Center showed that perceptions of the US declined significantly as a result of the invasion of Iraq, especially in the Middle East and Central Asia. This is undoubtedly a challenge for the US, but arguably an even bigger challenge for the UK, which due to its size and power relies much more on diplomacy and coalition-building in order to achieve its goals within various international treaty frameworks. The accuracy of the US/UK intelligence on Russia’s invasion, coupled with their sharing it openly, may well have restored faith in their capabilities and analysis. Over nearly two decades, the US and the UK no longer seemed to enjoy the same foundation of trust, even with close allies, as they did previously. This changed in February 2022. Towards the end of 2021, both the US and the UK were sounding the alarm about an impending Russian invasion of Ukraine based on information and analysis from their intelligence services. Despite the amassing of Russian troops, tanks and artillery on the border clearly visible from the air and by satellite imagery, several allies remained unconvinced until the invasion happened. This was in part due to their own assessments which indicated that Russia would stop short of an invasion, and in part because allies were unwilling to take US and UK statements on faith, without being able to assess the information themselves. US officials found this frustrating as it meant that NATO and the EU were slower off the mark with support for Ukraine than they might otherwise have been. However, the accuracy of the US/UK intelligence on Russia’s invasion, coupled with their sharing it openly, may well have restored faith in their capabilities and analysis. A more open approach to intelligence Over the last few years, there seems to have been a change in accepted practice regarding sharing and using intelligence. The UK Ministry of Defence has taken a much more open approach to intelligence in the war in Ukraine, sharing the most recent defence information publicly in order to counter Russian disinformation. This is a positive step to ensure that intelligence can be discussed and assessed critically. Being more open about secret intelligence may also be linked to the increasing capabilities of open-source intelligence (OSINT). Non-governmental and international organizations and the media all now have access to data from, for example, imaging satellites and can independently verify information coming from governments. Perceived double standards A reduction of trust in US and UK intelligence was not the only impact of the invasion of Iraq. Russia and China have repeatedly called out the US and UK for acting without a second UN Security Council mandate. Putin uses the decision to invade Iraq, as well as the NATO humanitarian intervention in Kosovo, to justify Russia’s actions in Crimea. He invokes parallel language to spread disinformation about a ‘responsibility to protect life’ of the (‘ethnically Russian’) Crimean population. Russia has also repeatedly used the WMD trope to create false narratives around Ukrainian biosecurity laboratories to justify Russian military actions against Ukraine. Putin uses the decision to invade Iraq, as well as the NATO humanitarian intervention in Kosovo, to justify Russia’s actions in Crimea. Deciding to invade Iraq under what turned out to be a false pretext has weakened the application of the international rule of law and has led to a perceived double standard whereby powerful states can use UN processes in their favour, or completely disregard them if they do not deliver their goals. As the Chilcot Inquiry found, there was very little preparation for the post-invasion period either in the US or the UK. Confirmation bias led not only to trusting shaky intelligence but also to believing in a best-case scenario and a ‘relatively benign security environment’ once the invasion had prevailed. Mismanaging the country’s occupation afterwards also led to the perception that the UK and US are less competent than projected. Problems for the international order The Iraq War has left many smaller and medium-sized states outside Europe and North America with the impression that powerful states are not committed to an equitable international system and instead will bend the rules to suit them while nonetheless holding other states to account. This dynamic poses a serious problem for the international system. It opens the door to ‘whataboutism’ in Russia’s false justifications for invading Ukraine and undermines faith in international law, destabilizing the international order in the longer term. Beyond the immediate challenges of dealing with the war in Ukraine, reforming and strengthening the international order to make it more equitable will be one of the most significant challenges the US and UK will face over the next decade. A trust deficit Domestically, for already disappointed citizens, the deceit over intelligence it is yet another piece of evidence which suggests that their government is not trustworthy and may not have their best interests at heart. This has profound implications for US and UK democracies, making it harder for governments to counter citizens’ susceptibilities to disinformation campaigns. Full Article
rc Discordant Protein and mRNA Expression in Lung Adenocarcinomas By www.mcponline.org Published On :: 2002-04-01 Guoan ChenApr 1, 2002; 1:304-313Research Full Article
rc GPS 2.0, a Tool to Predict Kinase-specific Phosphorylation Sites in Hierarchy By www.mcponline.org Published On :: 2008-09-01 Yu XueSep 1, 2008; 7:1598-1608Research Full Article
rc The Paragon Algorithm, a Next Generation Search Engine That Uses Sequence Temperature Values and Feature Probabilities to Identify Peptides from Tandem Mass Spectra By www.mcponline.org Published On :: 2007-09-01 Ignat V. ShilovSep 1, 2007; 6:1638-1655Technology Full Article
rc Addressing Russia’s use of forced displacement in Ukraine By www.chathamhouse.org Published On :: Thu, 17 Oct 2024 13:12:14 +0000 Addressing Russia’s use of forced displacement in Ukraine 7 November 2024 — 12:30PM TO 2:00PM Anonymous (not verified) 17 October 2024 Chatham House and Online Experts consider the role international law could play in responding to Russia’s forcible movement of people during its war against Ukraine. In the two and a half years since its full-scale invasion of Ukraine, evidence has emerged of Russia’s use of forced deportation and forcible transfer. Russia has also employed arbitrary detention as a tool of war and occupation.Much attention has been on the International Criminal Court’s arrest warrants against Russian President Vladimir Putin and his children’s commissioner Maria Alekseyevna Lvova-Belova. These warrants were issued in relation to the alleged war crimes concerning the unlawful deportation of children from Ukraine to Russia and the unlawful transfer of thousands of children from occupied areas of Ukraine.Meanwhile, Ukrainian citizens are being arrested and sent to Russia to serve prison sentences. They are often detained without charge and conviction.This panel discussion explores:What evidence is emerging of Russia using unlawful deportation and transfer of children, and the arbitrary detention of civilians?What is the role and significance of international law on these issues?What challenges might these practices create for later peace negotiations, as well as the securing of justice?What is the process of releasing illegally detained Ukrainians, and Ukrainian children in particular, and reuniting them with their families? How do Russian volunteers inside Russia cooperate with Ukrainian NGOs to facilitate family reunification?The event includes a screening of part of the documentary After the Rain: Putin’s Stolen Children. The institute occupies a position of respect and trust, and is committed to fostering inclusive dialogue at all events. Event attendees are expected to uphold this by adhering to our code of conduct. Full Article
rc Egypt’s purchase of a Chinese fighter jet is a reminder Cold War tactics are back in the Middle East By www.chathamhouse.org Published On :: Fri, 18 Oct 2024 09:03:13 +0000 Egypt’s purchase of a Chinese fighter jet is a reminder Cold War tactics are back in the Middle East Expert comment LJefferson 18 October 2024 The Egyptian army is a formidable force lacking air superiority capabilities to match its size and ambitions. China understood this predicament and offered to help. The reported agreement for Egypt to buy the Chinese Chengdu J-10C 4.5 generation fighter jets is part of a broader shift from focusing on modernizing ground troops to bolstering the air force. The details of the deal have not yet been published. Nonetheless, it reveals Egypt has two motivations beyond backing its arsenal with another fighter jet.Elusive Western technologyThe most important motivation for Egypt’s military diversification strategy (and the biggest source of frustration) is the perceived Western technology starvation. A quick examination of the map around Egypt shows that the most significant perceived threats to its national security are located in remote places where Egypt doesn’t traditionally enjoy ground troops’ presence. These include Ethiopia, the Southern Red Sea, Libya and the vulnerability a potential Israel–Iran regional war would create. From the generals’ perspective in Cairo, this list is more than a catalyst to build a modern and capable long arm.The race started in 2015 after the Obama administration paused an arms transfer to Cairo in 2013 that included four F-16C Block 52 fighter jets amid toppling the Muslim Brotherhood government. The psychological effect of Washington’s decision in Cairo increased Egypt’s risk tolerance towards challenging its military ties with the US by diversifying away from it. Egypt ordered the MiG-29M2 fighter jets from Russia and the French Rafales this same year. In 2018, Egypt negotiated a $2 billion deal with Russia to purchase the Su-35 fighter jet, seen in Washington as crossing a red line and triggering a warning to Egypt that it would impose sanctions under the Countering America’s Adversaries Through Sanctions Act (CAATSA). This caused the deal to collapse. Related content The Fatah–Hamas agreement increases Chinese influence in Palestinian affairs. But the road to unity is rocky The main factor of the US military sales in the Middle East is the upholding of the Israel Military Qualitative Edge principle over its neighbours. This principle requires the US to ensure Israel is superior over other regional countries’ strategic military capabilities, especially in air power.For Egypt, this has long been a strategic vulnerability. The US turned down multiple requests by Egypt to purchase the active radar long-range AIM-120 AMRAAM fire-and-forget missile that can be launched from the F-16 fighter jets, the main striking force in Egypt’s arsenal. Unlike the Gulf and other states (such as Jordan and Turkey), Egypt was only allowed the old AIM-7 Sparrow and the AIM-9 Sidewinders, which are shorter in range and technologically inferior. Israel also allegedly pressured the Trump administration to refuse Egypt’s request to buy the F-35 stealth fight jets in 2019.The US and Israel reportedly pressured France to not sell to Egypt the MBDA’s Meteor 100 km air-to-air missile with the Rafale fighters. Instead, Egypt received the 80 km MICA missile as part of the deal to buy 30 Rafales in 2021. Acquiring this advanced radar system and long-range missiles was likely behind Cairo’s deal to purchase 24 Eurofighter Typhoon aircraft from Italy in 2022. However, it is unlikely that they will come with the full package.Egypt thought the Chinese J-10C Vigorous Dragon fighter may solve this predicament. The Chinese fighter has a beyond-visual range AESA radar and can carry the PL-15 200 km air-to-air missile, similar to the Rafale’s Meteor. The J-10C’s price tag is attractive for Egypt at $40-50 million, much less than the F-16 and Rafales.The Chinese fighters are also a hedge against Russia’s sanctioned fighter jets, traditionally a second choice for the Egyptian air force.Risky manoeuvres This doesn’t mean Egypt is on a path to abandon its weapons purchases from its Western partners. Egyptian weapons procurement policy is not only motivated by technical considerations. It also serves political objectives. Egypt still receives $1.3 billion every year in military and economic aid from Washington. Regime security and backing are two objectives that will likely encourage Cairo to rely on Western weapons systems for decades. However, from Egypt’s military perspective, the time may have come to resort to the Cold War tactics of diversification and counterbalancing. Being forced to accept old technology during the significant modernization of its air force creates a technical and operational necessity to seek this technology elsewhere. Egyptian weapons procurement policy is not only motivated by technical considerations. It also serves political objectives. The regional uncertainty since Hamas’s 7 October attack on Israel and the war that followed in Gaza, southern Lebanon, and Israel’s intermittent confrontations with Iran makes make it imperative for the Egyptian strategic planners to take risky manoeuvres while targeting specific capabilities they seem desperate to acquire. The threat to deploy CAATSA sanctions against Egypt in 2019 makes the J-10C deal with China an interesting case study for all Middle Eastern allies of the West. It shows an uptick in Egypt’s risk tolerance to overcome its technological dilemma. It allows other countries considering the Chinese fighters (mainly Saudi Arabia) to gauge Washington’s reaction and design their future approach accordingly. Another motivation is to pressure the US, UK, and their allies to reconsider their implicit embargo on certain advanced technology by showing that Cairo now has alternatives. This tactic seems to work. General Frank McKenzie, the former head of US Central Command, said during a congressional hearing in 2022 that Washington will finally provide Egypt with the F-15 heavy-weight air superiority fighter, a longstanding demand by Cairo.Building favoursThe J-10C fighter jet ticks all the boxes: It satisfies Cairo’s diversity strategy and technological needs. It is under the sanctions threshold since it is less technologically savvy than the most controversial J-20 5th generation fighters, the equivalent to Russia’s SU-35. And it takes Egypt’s military partnership with China to a new level. A heavyweight military power like Egypt relying on Chinese fighters would almost certainly boost China’s share in the regional weapons market. The rumour that the Chinese fighters are bought to replace the ageing versions of Egypt’s significant F-16 fleet is a source of pride for Beijing since its military technology started to be seen as a competitor to Western technology. A heavyweight military power like Egypt relying on Chinese fighters would almost certainly boost China’s share in the regional weapons market, just like Cairo’s purchase of the Rafale boosted its popularity globally. Full Article
Related content The Fatah–Hamas agreement increases Chinese influence in Palestinian affairs. But the road to unity is rocky
rc In conversation with James Manyika, Senior Vice President of Research, Technology and Society at Google By www.chathamhouse.org Published On :: Tue, 29 Oct 2024 11:57:14 +0000 In conversation with James Manyika, Senior Vice President of Research, Technology and Society at Google 12 December 2024 — 11:15AM TO 12:45PM Anonymous (not verified) 29 October 2024 Chatham House and Online A conversation on AI’s global, societal and economic impacts. 2024 has been a landmark year for Artificial Intelligence (AI) development, deployment and use, with significant progress in AI-driven science, governance and cooperation. Looking ahead, AI continues to demonstrate economic promise and potential to expand on scientific breakthroughs in areas such as climate and health. This wave of innovation is occurring against a backdrop of geopolitical uncertainty and not all countries are fully able to participate. Heading into 2025, there are urgent questions about how best to maximise shared opportunities when it comes to AI and to advance global cooperation.James Manyika, Senior Vice President of Research, Technology & Society at Google, will unpack what 2025 will bring for AI in science, economics, global governance and international cooperation. Key questions include:What will be AI’s global societal and economic impact in 2025 and beyond? What are the ways AI could help increase economic growth and economy-wide productivity? What factors must be in place for this to happen?How best can we maximise shared opportunities and advance global cooperation when it comes to AI? Where can public-private partnerships unlock scientific breakthroughs for societal progress, combatting shared global challenges such as climate change and global health issues? What are the principles of safe, responsible AI, and how should companies remain responsive to their evolution and integrate them into technology design and implementation? What is the current – and ideal – role of technology companies in emerging mechanisms for global cooperation and national governance on AI?This event is being held in partnership with Google.You will receive notice by 13:00 on Wednesday 11 December if you have been successful in securing an in-person place.The institute occupies a position of respect and trust, and is committed to fostering inclusive dialogue at all events. Event attendees are expected to uphold this by adhering to our code of conduct. Full Article
rc The UK needs to address growth and debt problems if it is to match resources to ambitions on international priorities By www.chathamhouse.org Published On :: Tue, 05 Nov 2024 09:34:10 +0000 The UK needs to address growth and debt problems if it is to match resources to ambitions on international priorities Expert comment LJefferson 5 November 2024 The budget marks the lowest amount in decades the country has spent on development, and it is struggling to fund other international priorities too. The UK’s Chancellor Rachel Reeves unveiled her much-anticipated budget last week, the first of the new Labour government. Labour is in a difficult place. There are numerous calls on the public purse and public services are not performing well. Meanwhile, public debt remains close to 100 per cent of GDP, and there has been a long run of sluggish growth. Reeves argues with some justification that the previous government left her a challenging inheritance – gaps in this year’s spending plans, and persistent debt questions left unresolved. More importantly, there are longer-term concerns about the sustainability of UK public spending – the country’s Office for Budget Responsibility has warned public debt could triple by the 2070s due to an ageing population, the climate crisis, and security risks. The focus has understandably been on kitchen table questions about tax rises and funding public services. But this picture also has longstanding implications for international policy – on whether the UK can afford to invest in its foreign policy. The Chancellor did announce an increase of £2.9bn for defence. But the question of whether the UK can get on a sustainable path to spending 2.5 per cent of GDP on defence is still being worked through in the ongoing Strategic Review, and remains challenging despite increasingly urgent warnings from parliamentary committees about the UK’s defence readiness. Related content Independent Thinking: Will debt constrain Western foreign policy? The budget also marks one of the lowest amounts in recent years the UK will spend on development overseas, despite setting an ambition to reset relations with the Global South and recover the UK’s role as a leader in international development. The UK needs to either match resources to ambition, spend much more efficiently, or, in the case of the aid budget, it could seek to focus on priorities that are less dependent on spending. But even this will still require consistent resources, alongside significant diplomatic attention, intellectual leadership, and focus.Longer-term, the UK may need to consider larger questions: addressing broader problems with its lack of growth and productivity will be critical to fund an expansive international role.With this budget, UK aid spent overseas is at a historic lowIn 2020 the UK government cut its goal for spending on international development to 0.5 per cent of Gross National Income (GNI), ending a longstanding policy of spending 0.7 per cent. Labour have echoed this, promising to only return to previous levels when fiscal circumstances allow. But this masks a bigger issue. Since 2022, significant amounts of the UK’s aid budget have been spent on accommodation for asylum seekers in the UK. This is within the rules governing aid, but reduces the amount spent on reducing poverty overseas. In 2023 this spending was 28 per cent of the £15.4bn aid budget. In 2016, it was 3.2 per cent. Previous Chancellor Jeremy Hunt quietly allowed a top-up of aid spending over the last two fiscal years to offset how much is being spent at home on asylum seeker accommodation. That provided an additional £2.5 billion for 2022–23 and 2023–24. Related content In conversation with the Rt Hon Anneliese Dodds But Rachel Reeves declined to provide extra funding this time, meaning the amount being spent overseas is likely the lowest its been since 2007 – an effective cut – under a Labour government.The Minister for Development, Anneliese Dodds, speaking at Chatham House last month, said the government is working on clearing the backlog of asylum claims, which should free up more to spend overseas.But beyond this there has been little clarity on plans to address the issue. And costs for asylum seeker accommodation have increased significantly – the UK appears to spend much more than comparator countries per head, according to the Center for Global Development, raising questions about how this spending is managed.Development is not just about money – but money is importantThe UK debate about development has often focused on the 0.7 per cent figure, which can distract from larger questions about what development policy is intended to achieve. As many experts have argued, development aid is about more than spending, and the wider, complex process by which the UK contributes to broad-based growth and stability for poorer countries is not about hitting a specific number. There are things the UK can do that aren’t about spending more directly. This might include focusing on priorities like reforming multilateral development banks so they provide more low-cost public finance, and more flexible and agile loans to poorer countries – a priority echoed by Dodds. It might also incorporate focusing more broadly on helping developing countries attract more investment to bolster growth. The UK debate about development has often focused on the 0.7 per cent figure, which can distract from larger questions about what development policy is intended to achieve. There is also the issue of developing country debt, much of which is held by the private sector. Dodds previously said, when she was shadow chancellor, she might consider changing the law to address this issue. However, she declined to recommit to this when questioned at Chatham House. None of this can be done unilaterally – on debt, for example, the UK has spearheaded some creative policies. Its UK Export Finance body developed climate-resilient debt clauses – agreements that countries can pause debt repayments in the event of a climate shock – but the UK holds limited amounts of developing country debt. Impact will only come by galvanizing and coordinating others to adopt similar approaches. 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rc Undercurrents: Episode 6 - Tribes of Europe, and the International Women's Rights Agenda at the UN By f1.media.brightcove.com Published On :: Thu, 19 Apr 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 7 - Libya's War Economy, and Is the United Nations Still Relevant? By f1.media.brightcove.com Published On :: Fri, 04 May 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 8 - Ronan Farrow on Diplomacy By f1.media.brightcove.com Published On :: Thu, 17 May 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 9 - Digital Subversion in Cyberspace, and Oleg Sentsov's Hunger Strike By f1.media.brightcove.com Published On :: Fri, 01 Jun 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 10 - Artificial Intelligence in International Affairs, and Women Drivers in Saudi Arabia By f1.media.brightcove.com Published On :: Fri, 15 Jun 2018 00:00:00 +0100 Full Article
rc Undercurrents: Bonus Episode - How Can Political Elites Reconnect With Voters? By f1.media.brightcove.com Published On :: Fri, 29 Jun 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 11 - New Approaches to Peacebuilding, and Gender-Inclusive Growth at the G20 By f1.media.brightcove.com Published On :: Wed, 04 Jul 2018 00:00:00 +0100 Full Article
rc How to Fix Finance by Reinforcing Human Rights By f1.media.brightcove.com Published On :: Wed, 11 Jul 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 12 - Trump's Visit to the UK, and Japanese Foreign Policy in Asia By f1.media.brightcove.com Published On :: Thu, 12 Jul 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 13 - India's Billionaires, and Sexual Exploitation in the UN By f1.media.brightcove.com Published On :: Thu, 26 Jul 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 14 - Sustainable Energy for Refugees and Australian Foreign Policy By f1.media.brightcove.com Published On :: Fri, 10 Aug 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 15 - Brexit Update, and Corruption in the World of the Global Super-Rich By f1.media.brightcove.com Published On :: Thu, 23 Aug 2018 00:00:00 +0100 Full Article
rc Undercurrents - Episode 16: Cybercrime in the GCC States, and Fiction from Refugee Camps By f1.media.brightcove.com Published On :: Thu, 06 Sep 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 17 - Alastair Campbell on New Labour and Brexit, Alistair Darling on the Financial Crisis By f1.media.brightcove.com Published On :: Thu, 20 Sep 2018 00:00:00 +0100 Full Article
rc Managing the Real and Perceived Challenges Facing the World By f1.media.brightcove.com Published On :: Mon, 24 Sep 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 18 - The American Dream vs America First, and Uganda's Illegal Ivory Trade By f1.media.brightcove.com Published On :: Thu, 04 Oct 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 19 - Green Building Projects in Jordan, and Qatar's Football World Cup By f1.media.brightcove.com Published On :: Thu, 18 Oct 2018 00:00:00 +0100 Full Article
rc Undercurrents: Episode 20 - #MeToo and the Power of Women's Anger By f1.media.brightcove.com Published On :: Thu, 01 Nov 2018 00:00:00 +0000 Full Article
rc Undercurrents: Episode 21 - EU-US Relations after the Midterms, and Tackling the Illegal Wildlife Trade in Africa By f1.media.brightcove.com Published On :: Fri, 09 Nov 2018 00:00:00 +0000 Full Article
rc Women in the Armed Forces: Improving Integration By f1.media.brightcove.com Published On :: Tue, 13 Nov 2018 00:00:00 +0000 Full Article
rc Undercurrents: Episode 22 - China's Belt and Road Initiative, and the Rise of National Populism By f1.media.brightcove.com Published On :: Thu, 22 Nov 2018 00:00:00 +0000 Full Article
rc Undercurrents: Episode 23 - Robin Niblett on the Future of Think-Tanks By f1.media.brightcove.com Published On :: Thu, 06 Dec 2018 00:00:00 +0000 Full Article
rc Dark Commerce: Technology’s Contribution to the Illegal Economy By f1.media.brightcove.com Published On :: Tue, 11 Dec 2018 00:00:00 +0000 Full Article