A system and method for creating a medicated atmosphere in an organ, or body cavity is disclosed. The system includes a flexible nebulization catheter that can be manipulated during use, a device for the introduction of the nebulization catheter, a medication delivery apparatus configured to control delivery of a medication to the catheter, a gas delivery apparatus in communication with the catheter, a gas pressure relief apparatus configured to relieve pressure in the organ or body cavity, and a central controller. The system may include a liquid source having a mixture of hyaluronic acid and heparin that, in conjunction with the nebulizing catheter, are designed to generate an aerosol with a particle size of 10-25 microns in a body cavity. The method includes providing an aerosol of anti-adhesive medication to an organ or body cavity while controlling overall pressure in the organ or cavity.

A nasal mask has a flexible bottom edge portion and side portions. A delivery device includes a holding chamber coupled to the nasal mask. A method of delivering an inhalable substance includes positioning a nose of a user in a cavity of the nasal mask, inhaling through the nose, and orally soothing the user with a soothing device.

An umbilical system for sourcing and delivering within a flexible protective covering, a plurality of different breathing gasses, safety tether, a plurality of ancillary lines for remotely distributable, documentable, multidirectional, multi-format data/communications acquisition and delivery, personal/situational awareness and ancillary power sources for tool, accessory or device enervation, to a plurality of Users in an adverse environment.

An assembly for a counter mechanism for a drug delivery device is described comprising a drive member, wherein the drive member is adapted and arranged to be rotated in a first rotational direction and to be prevented from rotation in a second rotational direction which direction is opposite to the first rotational direction, an advancing member adapted and arranged to be axially moved and rotated with respect to the drive member, wherein the advancing member is adapted and arranged to mechanically cooperate with the drive member such that the drive member is rotated in the first rotational direction, and a display member which is configured to count a number of doses and to display the counted number of doses, wherein the assembly is adapted and arranged such that rotation of the drive member in the first rotational direction is converted into a counting movement of the display member. Furthermore, a drug delivery device comprising the assembly is described.

A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.

An add-on logging device (100, 300) mounted to a drug delivery device is turned on when the cap is removed. After a given amount of time in inactivity the sensor means of the add-on device is turned off automatically to save energy. If the user takes a dose of drug this is not detected as the add-on device is only turned on when the cap is removed. According to the present invention a warning message is provided when the cap is re-mounted after the sensor means has been turned off automatically, the warning message indicating to a user that an expelled dose may not have been detected.

The invention is directed to a dose indicating mechanism for drug delivery device (1) configured for the delivery of a medicament contained in single medicament cartridge (2), the medicament comprising at least one first drug and one second drug, wherein the dose indicating mechanism comprises a body (3), a dose dial component (7) configured to move relative to the body (3) during dose setting and first dose indicator means (10) configured to display a set dose of the medicament and/or of first drug in dependence of the displacement of dose dial component (7) during dose setting. In order to provide the user with further information, a second dose indicator means (15) is provided that is configured to display a set dose of the second drug during dose setting. The invention is also directed to a respective drug delivery device.

A drug delivery device is provided herein, the device including a reservoir for containing a medicament. The medicament includes a suspension of solids in a liquid carrier. The device also includes a needle having a distal end for injection into a patient, a proximal end in communication with the reservoir, and a lumen extending between the distal and proximal ends. A path is defined from the reservoir to the distal end of the needle through the lumen, the path having an inner diameter that decreases in a proximal to distal direction along at least a portion thereof. Advantageously, with the subject invention, a flow path may be defined which provides a more gradual transition in diameter from the reservoir to a distal tip of the needle. In this manner, changes in velocity of the suspension may be less abrupt than in the prior art, thus better maintaining solid particles in the suspension.

Medical devices, methods and kits are described. An exemplary medical device comprises a catheter that has a catheter wall and defines a catheter lumen, a bend, and a coil disposed distal to the bend. The catheter defines one or more apertures that extend through the catheter wall and are in communication with the catheter lumen.

A catheter includes a catheter body having a proximal end, a beveled distal end, and a lumen therethrough. The beveled distal end defines an elliptical port for releasing contrast or other media through the lumen and from the elliptical port. The catheter may also be used delivering devices or for aspirating or extracting materials from the vasculature or other body lumens. A fixed guidewire extends distally from the distal end of the catheter body, typically from the distal-most edge of the elliptical port. The fixed wire is typically malleable so that it can be manually formed into a desired shape. The elliptical port may be flat or concave.

A drug delivery balloon apparatus is disclosed herein, comprising: (a) at least two lumens, comprising a first lumen and a second lumen, (b) a balloon inflation port in fluid communication with the first lumen, (c) a drug delivery port in fluid communication with the second lumen, (d) a guidewire port in fluid communication with the second lumen, wherein the second lumen is configured to receive both a guidewire and a drug solution, (e) an occlusion balloon, (I) a drug delivery balloon, where the occlusion balloon and the drug delivery balloon are in fluid communication with the first lumen, (g) one or more drug delivery channels extending the length of the second lumen, and (h) one or more drug delivery ducts extending from the one or more drug delivery channels to an exterior surface of the second lumen.

Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.

A transdermal drug delivery device comprises: a reservoir for holding a drug; and at least one microneedle in fluid communication with the reservoir through which the drug can be delivered transdermally, wherein the transdermal drug delivery device is concealed from view during operation thereof.

A device for delivery of material or stimulus to targets within a body to produce a desired response, the targets being at least one of cells of interest, cell organelles of interest and cell nuclei of interest. The device includes a number of projections for penetrating a body surface, with the number of projections being selected to produce a desired response, and the number being at least 500. A spacing between projections is also at least partially determined based on an arrangement of the targets within the body.

The chamber of commerce is maintaining a list of local eateries still open for business. The Oakland Chamber of Commerce has compiled a list of more than 175 Oakland restaurants offering takeout or home delivery. The City of Alameda had a similar idea, and has created a website listing about 85 restaurants.…

Oakland-based Cream Co. Meats announced recently that, for the first time ever, it will start delivering its products on a retail basis. Statewide Covid-19-related shelter-in-place regulations mandated the closure of many restaurants and other businesses that regularly serve and sell Cream Co. products.…

The present invention relates to a delayed fluorescence-quantum dot (QD) electroluminescent diode, the delayed fluorescence-quantum dot electroluminescent diode includes an anode, a cathode, and a light emitting layer located between the anode and the cathode, and the light emitting layer includes a QD and a delayed fluorescence material which supplies energy to the QD.

Certain aspects pertain to methods of fabricating an optical device on a substantially transparent substrate that include a pre-deposition operation that removes a width of lower conductor layer at a distance from the outer edge of the substrate to form a pad at the outer edge. The pad and any deposited layers of the optical device may be removed in a post edge deletion operation.

Summer’s now over, and sadly there’s little you can do to repair a holiday ruined by flight delay or cancellation (eg from a strike like Ryanair’s) but many are entitled to up to £550 per person compensation. In fact this applies even for delays as far back as 2012.

Scott Rendell struck against former club Woking to earn Eastleigh a point as they extended their unbeaten run to eight matches.

Scott Rendall admitted his confidence is sky high after his fine goalscoring continued with a match winning hat-trick.

updating with pars 15 & 16.

Ryan Garner's return to the ring has been delayed by a month.

DRIVERS are facing delays as a key Hampshire road closes for works.

ENVIRONMENT Secretary, George Eustice, says fast-food restaurants like KFC, McDonald's and Burger King can re-open for deliveries and take-aways, but stressed the need for safety and social distancing.

ONE of the largest independent food wholesalers in the south has rapidly turned itself into a home delivery service along the same lines as the supermarkets.

Earlier this year Apple came under some criticism after a report by the Guardian on how Apple hired contractors to listen to a small percentage of anonymized ‌Siri‌ recordings to evaluate the responses with the purpose of improving accuracy and reliability.

In response, Apple promised that it would introduce options in a forthcoming update that would allow users to opt out of sharing their audio recordings.

Those options arrived with the releases of iOS 13.2, iPadOS 13.2, and macOS 10.15.1.

In this podcast, Tyler walks us through how to access and change these new options.

Delaware County Sheriff's deputies say they have solved the 36-year-old murder of a teen.

The beloved, charismatic Del & the Boys have visited us more than a time or two over the years, and this one from September 25th, 1998 has never aired since that date. What say we revisit it again? "Well all RIGHT!"

Release date : TBA 2020
Synopsis : The film follows Vietnam veterans who return to the jungle to find their lost innocence. Searching for the remains of ...

Release date : June 19, 2020
Synopsis : When seriously ill teenager Milla (Eliza Scanlen) falls madly in love with smalltime drug dealer Moses (Toby Wallace), it's her ...

The former Destiny's Child member admits she's inept at using music software so she's not as productive as she wanted to be during the ongoing coronavirus lockdown.

In the video, Tyra advises contestant Danielle Evans to close the gap in her front teeth, saying, 'Do you really think you can a have a covergirl contract with a gap in your mouth?'

The creator/host of the long-running modeling competition finds herself under fire after a clip from a past episode in which she confronted Dani Evans about the gap in her teeth came out online again.

Pete Geracimo who helped the 'Chasing Pavements' hitmaker during her weight loss journey comes to the singer's defense as she is facing criticisms online.

The retired NBA player has sent a thousand of free pizzas to the key workers during the ongoing coronavirus lockdown at police stations and local hospital in Miami.

The creator/host of the long-running modeling competition finds herself under fire after a clip from a past episode in which she confronted Dani Evans about the gap in her teeth came out online again.

A federal judge has delayed the sentencing of former Nassau County Executive Edward Mangano and his wife for their corruption convictions.

Region’s showcase of ambitions sees 50% increase in media profile.

Dean Delray, Comedian and Host of the "Let There Be Talk" podcast, joins Joey Diaz and Lee Syatt in studio.

Rudy Sarzo, Musician and Bass Player who has played with, among others, Black Sabbath, White Snake and Quiet Riot joins Dean Delray, Comedian and Host of the "Let There Be Talk" podcast, with Joey Diaz and Lee Syatt in studio.

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Dean Delray, Comedian and Host of the "Let There Be Talk" podcast, joins Joey Diaz and Lee Syatt in studio.

Dean Delray, Comedian and Host of the "Let There Be Talk" podcast, joins Joey Diaz and Lee Syatt in studio.

Raanen Bozzio, professional drummer  and son legendary drummer Terry Bozzio, and Dean Delray, Comedian and Host of the "Let There Be Talk" podcast, join Joey Diaz and Lee Syatt in studio.