tam

ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction

RSC Adv., 2024, 14,13083-13094
DOI: 10.1039/D4RA00748D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jiahui Huang, Tanja Osthushenrich, Aidan MacNamara, Anders Mälarstig, Silvia Brocchetti, Samuel Bradberry, Lia Scarabottolo, Evandro Ferrada, Sergey Sosnin, Daniela Digles, Giulio Superti-Furga, Gerhard F. Ecker
Predict SLC6 mutation clinical pathogenicity by calculating the amino acid descriptors in different ranges with rationalization analysis of the prediction.
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tam

Versatile poly(N-vinylcaprolactam)-grafted-hydroxypropyl cellulose polymers with tailored thermo- and pH-responsive properties via sustainable organocatalyzed atom transfer radical polymerization

Polym. Chem., 2024, 15,4244-4254
DOI: 10.1039/D4PY00931B, Paper
Muhammad Asif Iqbal, Asif Mahmood, Waheed Al-Masry, Chan Ho Park, Sadaf Ul Hassan, Toheed Akhter
This study explores the synthesis of dual pH- and thermo-responsive poly(N-vinylcaprolactam)-grafted-hydroxypropyl cellulose (PNVCL-g-HPC) polymers via visible-light-driven, metal-free organocatalyzed atom transfer radical polymerization (O-ATRP).
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tam

A near-infrared superoxide generator based on a biocompatible indene-bearing heptamethine cyanine dye

J. Mater. Chem. B, 2024, 12,11202-11209
DOI: 10.1039/D4TB01663G, Paper
Nikita Bel’ko, Anna Mal’tanova, Anastasiya Bahdanava, Anatol Lugovski, Sviatlana Fatykhava, Polina Shabunya, Adam Smaliakou, Sergey Poznyak, Tatsiana Kulahava, Michael Samtsov
A heptamethine cyanine dye with an indene moiety and 4-meso-chloride generates superoxide inside cells upon near-infrared photoactivation, inducing cell death.
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tam

Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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tam

Development of a Xanthene-Based NIR Fluorescent Probe for Accurate and Sensitive Detection of γ-Glutamyl Transpeptidase in Cancer Diagnosis and Treatment

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01841A, Paper
Chia-Kai Lai, KUPPAN MAGESH, Sivan Velmathi, Shu-Pao Wu
γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer. High GGT levels in tumors make it a valuable cancer biomarker. Current GGT detection methods often...
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tam

Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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tam

Bigg Boss 12: 'I am not a badtameez'

'While I was leaving, Sree told me I was one of the most genuine and nicest people he had ever met.''He said, "Virat Kohli and I were more aggressive than you at this age".'




tam

Tamil poet Subramania Bharati’s English writings and songs find a voice

On his 100th death anniversary on September 11, a new book and a podcast throw light on unknown facets of the literary icon




tam

Selection of DNA aptamers for detecting metronidazole and ibuprofen: two common additives in soft drinks

Analyst, 2024, 149,5482-5490
DOI: 10.1039/D4AN01186D, Paper
Jin Wang, Xiangmei Li, Hongtao Lei, Juewen Liu
Using capture-SELEX, short aptamers for metronidazole and ibuprofen were isolated and they can be used for the detection of these drugs illicitly added to soft drinks.
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tam

Rapper Iykki Berry’s new single celebrates Tamil pride and Thanjavur

Rapper and singer-songwriter Iykki Berry’s new single is a nod to Thanjavur, her hometown




tam

‘We are for Hockey’ Club at the forefront of promoting women’s hockey in Tamil Nadu

The ‘We are for Hockey’ Trophy for schools, colleges and clubs has attracted 16 teams from different parts of the state




tam

IOC beats Odisha, secures semifinal berth; Army downs Tamil Nadu




tam

Tamil Nadu scripts a 43-0 victory over Andaman & Nicobar, enters quarterfinals




tam

‘Linguistic minority school students find Tamil difficult’




tam

Poetry 101 : from Shakespeare and Rupi Kaur to iambic pentameter and blank verse, everything you need to know about poetry / Susan Dalzell

Dalzell, Susan, author




tam

Tablet fragments / Tamar Rubin ; Clarise Foster, editor

Rubin, Tamar, 1986- author




tam

Chasing the sound barrier, Tamil Nadu skaters aim high for India

As skaters from Tamil Nadu get ready for the World Skate Games to be held in Argentina later this year, we speak to some of the talented men and women on wheels




tam

Tamil theatre’s new voice: Chennai audiences cheer for fresh ideas and new faces

Tamil contemporary theatre in the city sees a promising resurgence as new faces debut on stage with fresh scripts and creative ideas




tam

Regulating water decontamination and food safety by a reusable, nano-sized MOF@cotton@chitosan composite through nanomolar detection of the drug nitroxinil and organoarsenic feed additive p-arsanilic acid

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D4EN00066H, Paper
Subhrajyoti Ghosh, Debjit Mal, Shyam Biswas
MOF@cotton@chitosan composite for nanomolar fluorescence sensing of nitroxinil drug and p-arsanilic acid in real samples is presented.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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tam

Discovery of unregulated contaminants in drinking water [electronic resource] : evidence from PFAS and housing prices / Michelle M. Marcus, Rosie Mueller

Cambridge, MA. : National Bureau of Economic Research, 2023




tam

10 injured in stampede at Mumbai’s Bandra station

The incident occurred when passengers tried to board the Gorakhpur Antyodaya Express amid festive rush; Rahul Gandhi says incident yet another example of India’s crumbling infrastructure




tam

Rail Minister too busy with bullet train, Mumbai passengers ignored: Raut on Bandra stampede

Mr. Raut also hit out at the NDA government at the Centre over some of the railway accidents in the country during its tenure




tam

After Bandra Terminus stampede, Central Railway imposes platform ticket sale restrictions to curb crowding

In a release issued during the day, CR said the platform ticket sale restrictions will be in force in Chhatrapati Shivjai Maharaj Terminus, Dadar, Kurla LTT, Thane, Kalyan, Pune and Nagpur stations with immediate effect.




tam

Bandra stampede: Railways takes measures to curb rush

Western Railway has erected a 370 sqm. waiting area at Bandra Terminus to accommodate 600 passengers; two persons, gravely injured on Sunday, remain critical and are on oxygen support




tam

Glimpse Of Tamannaah To Brighten Yr Day

Kajol has advice... Amyra has a question... Preity has an adorable doctor...




tam

Tamannaah, Kiara Give Us Ganpati Fashion

Bollywood's divas have been giving us #FashionGoals for the Ganpati festival.





tam

Synthesis of Asp-based lactam cyclic peptides using an amide-bonded diaminodiacid to prevent aspartimide formation

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00472H, Communication
Wen-Jie Li, Jun-You Chen, Hui-Xia Zhu, Yi-Ming Li, Yang Xu
A diaminodiacid (DADA) containing an amide bond can be used in Fmoc solid-phase peptide synthesis (SPPS) of an Asp-based lactam cyclic peptide with no aspartimide formation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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tam

Expanding the scope of the successive ring expansion strategy for macrocycle and medium-sized ring synthesis: unreactive and reactive lactams

Org. Biomol. Chem., 2024, 22,2985-2991
DOI: 10.1039/D4OB00285G, Paper
Open Access
Zhongzhen Yang, Marion Arnoux, Damien Hazelard, Owen R. Hughes, Joe Nabarro, Adrian C. Whitwood, Martin A. Fascione, Christopher D. Spicer, Philippe Compain, William P. Unsworth
New Successive Ring Expansion (SuRE) protocols are described for use on unreactive lactams, as well as iminosugar derived lactams.
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tam

Tiruchi man with mpox symptoms: Sample has returned negative, says Tamil Nadu Health Minister

The man, who had returned from Sharjah on October 31, was found to have fever during screening on arriving at the Tiruchi airport.




tam

Severe staff shortage leaves Tamil Nadu’s obstetricians and gynaecologists overworked

Doctors are forced to take turns doing frequent 24-hour shifts — in some cases two to three 24-hour shifts a week. Inquiries with government OB-GYNs reveal that several health facilities have been short-staffed for years, and vacant posts remain unfilled




tam

'Katrina didn't want to do Tamil version'

'It would have made (Producer) Ramesh Taurani very happy if I taken two Bombay stars, but the reason why I kept mentally rejecting the regular sort of casting was to discover this excitement, you know, can I crack it?'




tam

Exploring the Purushottama

The Purush Festival made a case for preserving space for male performers in classical dance forms




tam

Kanak Rele was a doyenne of Mohiniyattam who redefined and reinterpreted the traditional dance form of Kerala

In her passing, Mohiniyattam has lost a crusader who widened its repertoire and gave it a new aesthetics rooted in Kerala




tam

Restore incentive for cashew exports: Tamil Nadu Cashew Processors and Exporters Association

The association also urged APEDA to exempt imported raw cashew nuts from Food Safety and Standards Authority of India (FSSAI) clearance in customs.




tam

Watch | Director Gowtam Tinnanuri: The ‘Jersey’ you saw on screen was the ninth or 10th draft

Gowtam Tinnanuri, the reticent writer-director, talks about his unlikely journey into cinema and the learnings thus far. Next up is a film starring Vijay Deverakonda 




tam

Ravi Teja, Karthik Ghattamaneni film titled ‘Eagle’, eyes Sankranti 2024 release

Actor Ravi Teja’s new Telugu film to be directed by Karthik Gattamneni is titled ‘Eagle’, targets the Sankranti 2024 festive season for theatrical release




tam

Suzy Embo : foto's = photos, 1953-1980 / textes, Ivan Alechine, Tamara Berghmans, Ann Deckers, Pieter De Reuse.

Bruxelles : CFC-Editions, [2017]




tam

Inventario : disegni di figura / Gabinetto disegni e stampe degli Uffizi ; a cura di Annamaria Petrioli Tofani.

Firenze : L.S. Olschki, [1991]-[2004]




tam

Lost enlightenment : Central Asia's golden age from the Arab conquest to Tamerlane / S. Frederick Starr.

Princeton ; Oxford : Princeton University Press, 2013.




tam

Witness through troubled times : a history of the Orthodox Church of Georgia, 1811 to the present / with contributions by Zaza Abashidze [and four others] ; edited by Tamara Grdzelidze, Martin George & Lukas Vischer.

London : Bennett & Bloom, 2006.




tam

The immanent divine : God, creation, and the human predicament / John J. Thatamanil.

Minneapolis, MN : Fortress Press, [2006]




tam

Development of Polymeric Aptamer Probes for In Vivo Continuous Precision Cancer Targeting

Mater. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QM00731J, Research Article
Silin Huang, Yu-Ting He, Xiao-Jing Zhang, Xueqiang Wang, Qiang Guo
Aptamers, despite their specific targeting capabilities and widespread applications in various research domains, face a significant hurdle in biomedical research area due to their rapid degradation by nucleases. To address...
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tam

REPL to prepare GIS-based master plan for 12 ULBs of Tamil Nadu

REPL will conduct a thorough assessment of the existing conditions and identify development trends at the regional level




tam

Tamil Nadu projects a potential for 1.4 GW in wind repowering in the near term

The Tamil Nadu government has recently introduced its Repowering, Refurbishment, and Life Extension Policy for Wind Power Projects – 2024




tam

Tamil Nadu Green Energy Corp’s request to revise solar energy slot timings faces industry backlash

Limiting solar power usage at night may deter investors from pursuing new projects, say experts




tam

Optimization of informative variables selection for quantitative analysis of heavy metal (Cu) contaminated Tegillarca granosa using laser-induced breakdown spectroscopy

J. Anal. At. Spectrom., 2024, 39,2824-2831
DOI: 10.1039/D4JA00084F, Paper
Xudong Huang, Xiaojing Chen, Guangzao Huang, Zhonghao Xie, Wen Shi, Shujat Ali, Leiming Yuan, Xi Chen
The KMRCD algorithm successfully selected 50 informative variables from the 1520 variables in the LIBS spectra.
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tam

MIT researchers make stamp-size stickers that can scan the human body

MIT professor Xuanhe Zhao said the development could open a new era of wearable imaging.




tam

Gautam Adani overtakes Ambani to become Asia’s richest person again

Adani with a net worth of $111 billion is now ranked as the eleventh richest in the world, according to the Bloomberg Billionaires Index.