Harris has been criticized for not doing more media interviews

Southern States’ concerns need to be addressed by the Finance panel

Shop dabu-printed apparel, upcycled decor, and natural stone jewellery at this ongoing pop-up in the city

The second edition of Sondham features trendy koodais, handloom saris, and contemporary silhouettes in cotton

Even though the country is witnessing a growth in indigenous design, designers continue to find it difficult to break through. Stores like At-tin and Paper Boat Collective are coming up with ways to help them, says Sujatha Shankar Kumar

Factors encouraging their growth in India

Las marcas como Juul liberan una forma de nicotina menos agresiva al inhalarse que la nicotina en forma básica.

Brands like Juul deliver a form of nicotine that is less harsh to inhale than free-base nicotine

Adding enzyme to engineered yeast boosts production of thebaine, a key morphine intermediate

Ninja Van's country head Eric Saputra talks about the challenges and opportunities of operating in Indonesia.

The post Ninja Van sets its sights on Indonesia’s mom-and-pop e-commerce plays appeared first on DealStreetAsia.

Crowd wisdom tends to favor the most popular information, not necessarily the most correct — mass ignorance can cancel out a knowledgeable minority, resulting in the wrong answer becoming the most accepted. To improve wisdom-of-crowds surveys, Princeton University and the Massachusetts Institute of Technology researchers have developed what they call the "surprisingly popular" algorithm, wherein the correct answer is that which is more popular than people predict.

In many species, mating comes at the steep price of an organism's life, an evolutionary process intended to regulate reproductive competition. But Princeton University researchers report that males of the roundworm species Caenorhabditis elegans have doubled down with two methods of checking out after reproducing — a lethal gene activated after mating, and pheromones released by other males. The findings provide insight into how aging, longevity and population are naturally regulated for different species and sexes.

The former Palm Beach, Fla., home of John Lennon and Yoko Ono is for sale at $47.5 million.

Charlotte Web writes: Since 2001 the TIOBE Index has been ranking top results for the search query +"<language> programming" on the top 25 search engines. "This month, C moved up past Java and entered the number one position," reports JAXenter. "There's a new number one. (Or, should we say an old number one?)" "Java and C were already very close in April, but this month C surpasses Java again," explains Paul Jansen CEO TIOBE Software. He also points out that the last time C was number one was back in 2015, suggesting that today embedded software languages like C and C++ "are gaining popularity because these are used in software for medical devices." "On another note, it is also worth mentioning that Rust is really getting close to the top 20 now (from #27 to #21 within one month)." "Perl, on the other hand, might be on its way off of the charts," argues JAXenter, "if it continues its downward trend. This month it saw a rate of change of -0.51%. It is currently number 18 on the list, but in May 2019 it was number 13." Python also passed C++ to take the #3 spot, while C# overtook Visual Basic for the #5 spot. ("Classic Visual Basic" also lost the #16 spot to PL/SQL). Even PHP rose a notch, pushing past SQL to take the #8 spot, and Scratch also moved up one, overtaking Objective C for the #19 position.

Read more of this story at Slashdot.

Emacs "predates Linux, and was once far more popular," writes LWN.net, while adding that the text editor "has fallen into relative obscurity over the years." Then it reports on a "mega-thread" on the emacs-devel mailing list about how to make Emacs more appealing and attractive to users: The discussion started with a post from "ndame" asking why Emacs is "so square"; the appearance of things like buttons could be improved with rounded corners, they said. Richard Stallman, one of the original authors of Emacs, seemed somewhat dismissive in his reply: "Perhaps we should implement a mode that puts cosmetics on Emacs so it will appeal to those who judge by the surface of things." But Stefan Kangas thought there was more to it than that: I think it's unfortunate if we assume that this is all bells and whistles. Graphical design elements can also improve usability. I also don't know that it's helpful to assume that the rest of the world will take the enlightened stance.... He wondered if there was "any reason not to improve the default look". Stallman said that there are some technical barriers in finding someone interested in and capable of doing the work needed, but there is an overarching problem that needs to be addressed first: The code to interface Emacs to X-based GUIs needs rewriting by an expert, and has needed it for decades. Until it gets that rewrite, changes in it are likely to break something. Stallman did agree that the graphical design could improve usability, "but I have a feeling that the changes that would help are deeper issues than the shape of corners". It was a long and interesting discussion, touching on the popularity of both Vim and Visual Studio Code, while another post questioned whether Emacs should even be prioritizing its menu bar and tool bar. One post suggested "starter kits" to make the text editor more friendly to newcomers, another suggested making Cntrl-C cut-and-paste the default key binding, and one asked whether it was Emacs' terminology and keyboard shortcuts that might be confusing to users coming from Microsoft Word. "You are basically making a commitment to being or becoming a power user..." argued another post. "If you just want to do 'casual' text editing emacs is a very weird choice in 2020."

Read more of this story at Slashdot.

Although a robust inflammatory response is needed to combat infection, this response must ultimately be terminated to prevent chronic inflammation. One mechanism that terminates inflammatory signaling is the production of alternative mRNA splice forms in the Toll-like receptor (TLR) signaling pathway. Whereas most genes in the TLR pathway encode positive mediators of inflammatory signaling, several, including that encoding the MyD88 signaling adaptor, also produce alternative spliced mRNA isoforms that encode dominant-negative inhibitors of the response. Production of these negatively acting alternatively spliced isoforms is induced by stimulation with the TLR4 agonist lipopolysaccharide (LPS); thus, this alternative pre-mRNA splicing represents a negative feedback loop that terminates TLR signaling and prevents chronic inflammation. In the current study, we investigated the mechanisms regulating the LPS-induced alternative pre-mRNA splicing of the MyD88 transcript in murine macrophages. We found that 1) the induction of the alternatively spliced MyD88 form is due to alternative pre-mRNA splicing and not caused by another RNA regulatory mechanism, 2) MyD88 splicing is regulated by both the MyD88- and TRIF-dependent arms of the TLR signaling pathway, 3) MyD88 splicing is regulated by the NF-κB transcription factor, and 4) NF-κB likely regulates MyD88 alternative pre-mRNA splicing per se rather than regulating splicing indirectly by altering MyD88 transcription. We conclude that alternative splicing of MyD88 may provide a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restoration of normal tissue homeostasis once an infection is controlled.

In 1964, Millie Small made one of only two or three trips back to her homeland, Jamaica, and it is an occasion that is engraved in singer Dennis Alcapone’s heart. He was fortunate enough to have actually seen the sensational My Boy Lollipop singer...

The Nova Scotia government is going ahead with its annual lottery for moose hunting licences after the latest survey found Cape Breton moose numbers have rebounded from a low of 1,300 last year.

The Government of Hong Kong is increasing its efforts to attract foreign talent, including the mainland China’s professionals, as working population of the city is supposed to get shrink in the year 2018.The Immigration Director, Chan Kwok-ki said…

In West Virginia, where workers have harvested coal seams for centuries, Pope Francis’ new warning about the risks of fossil fuels will find skepticism even among the faithful.

Pope Francis turned a keen eye toward the environment and the problem of climate change with his encyclical,“Laudato Si” (“Praised Be”). As a clean energy advocate, I’m heartened that Pope Francis recognizes the need to transform our energy system.

As editors we delight in learning which of the stories that we wrote or commissioned were most popular with our readers. That’s why at the end of each calendar year, we pull reports that tell us which stories we posted got the most shares, the most views, the most comments, etc. We also look at which videos were watched the most. Often, we post articles that we know will be a big hit: like explanations of controversial solar legislation. But other times you surprise us, readers, by taking great interest in articles that we felt were solid but not necessarily ground-breaking.

In West Virginia, where workers have harvested coal seams for centuries, Pope Francis’ new warning about the risks of fossil fuels will find skepticism even among the faithful.

The Rivers State Police Command has rescued a Lebanese, Bilal Nosser from a kidnappers’ den in Ndashi forest, Etche Local Government Area of the state. Bilal, popularly known as Mister Bee is said to be a renowned Nollywood actor, who was kidnapped in the early hours of Friday in Imo State and taken to a […]

Police rescue popular Nollywood actor from kidnappers’ den

Governor Nasir El-rufai of kaduna state has reportedly demolished a popular beer joint located opposite command secondary schools in kaduna south local government. Eyewitness and security man who spoke to Nigerian pilot under anonymity said government official led by four Hilux loaded with security operatives were responsible for the demolition which occurred around 4pm on […]

The post Breaking: El-rufai demolish kaduna popular beer joint appeared first on Nigerian Pilot News.

Almost 500 possible breaches of level-3 rules have been reported to police this weekend, as many Kiwis prepare for what they hope will be a move to level 2 this week.People flocked to beach suburbs and took waterfront walks in cities...

Popov may have been first but he didn’t patent his inventions or try to commercialize them

Provincial health officials will open a second centre to test for COVID-19 in the southern Alberta city of Brooks, as an outbreak connected to a nearby slaughterhouse continues to grow.