You can publicly commit yourself to diversity in the workplace, put it in writing on social media, hire diversity officers, and shuttle tens of thousands of dollars into “diversity initiatives,” but if you don’t understand the complexities of creating an inclusive workplace, you’re not going to get any return on your investment. That’s probably not […]

The post Diversity initiatives are leaving Black women behind appeared first on DiversityJobs.com.

We’ve all seen the quotes from Wells Fargo’s CEO in a June memo in which he blamed the bank’s failure in reaching diversity goals on a lack of qualified minority talent. “While it might sound like an excuse, the unfortunate reality is that there is a very limited pool of black talent to recruit from,” […]

The post What employers can learn from Wells Fargo’s failure to recruit and retain Black talent appeared first on DiversityJobs.com.

Can’t wait until Black Friday to start your holiday shop or score a killer deal on a gadget you’ve been eyeing? You may not have to. Although Black Friday isn’t until November 29th, Best Buy, Walmart, and Target have begun rolling out their holiday discounts, many of which are available elsewhere.…

Shopping for clothing is one of my favorite past times — and with all the early Black Friday apparel sales happening now, it's starting to feel like Christmas morning! Apparel and shoes are seeing some of the biggest markdowns with popular brands like Lululemon, Nike, Adidas, Patagonia and more…

Free is Killing the Internet This is because of fake accounts on Facebook, Google, Pinterest, LinkedIn, Twitter and blogs which are the main source of the problem. These company’s should join Google and Bing by creating structured data. We will not even get into the scams and spammers coming from fake e-mail accounts on Yahoo! […]

In this article, we derive the gravitational time dilation factor in a new manner, which allows us to identify the mathematical cause of Schwarzschild radius, to give a theoretical way to avoid it and to compute properties of black hole. General relativity effects are computed as simple as in special relativity. Observability of black hole...

For Newtonian mechanics The Schwarzschild radius is the radius of the event horizon of a black hole. Amazingly, we can compute it with Newtonian mechanics, which is explained below. Consider a big mass M which creates the gravitational acceleration a for a small mass m at the distance r from M, see figure 1 and...

Carry Smith wrote her PhD thesis on the Voting Rights Act and challenges to the right to vote in Georgia. Now dig this: Smith, the expert on challenges to voting rights, lost her vote because a Republican vigilante challenged her registration—along with 900 other Savannah voters—until she was forced to... READ MORE

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There’s no better time to upgrade your sleep setup than Black Friday and Cyber Monday — two of the biggest sale events of the year. As usual, there are tons of great deals on top-rated mattresses, from trusted names like Tempur-Pedic and Mattress Firm to direct-to-consumer favorites like Purple and Naturepedic. We recommend taking advantage of all these sleep brands impressive sales, especially since a majority of them have already started. Yup, weeks ahead of schedule! READ MORE...

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The Advocacy Project works with older people and other groups across Glasgow and Lanarkshire to ensure their voice is heard, their needs met and their legal rights safeguarded. The organisation identified a low take up of their own service by older people from BME communities, which was generally held to reflect the wider picture in Glasgow in relation to health and social work services. This report was commissioned by them to examine barriers to access to services specifically for older people from BME communities in Glasgow South, where there is a high concentration of people from BME communities.

Thomas Taverner published this remarkable problem in the Dubuque Chess Journal in 1889. White is to mate in two moves.

In this episode I'm joined by Sam Dean to talk about Mikel Arteta signing a new contract, with discussion of the timing of the announcement, and what this next

cycle will demand of the Arsenal boss. Then we turn our attention to the injury-filled Interlull, paying close attention to the Martin Odegaard injury, and trying to figure out what Arteta is going to do without his captain – a player who is fundamental to the way the Gunners play.

Then, I catch up with Tayo Popoola, a contributor to the new book Black Arsenal by Clive Chijioke Nwonka and Matthew Harle. We chat about the significance of this publication, before Tayo catches up with Femi Koleoso - Drummer from Ezra Collective; Eddie Otchere - Photographer; and Amy Lawrence to go more in depth on the book and its themes.

Music – "Don Gargan Talk” by SPMC : “Cry Tuff Dub” by Tayo

Black Arsenal is available in all good bookshops now – please consider ordering from your local independent bookstore, rather than giving any tax-dodging corporation money they don't need.

Get extra bonus content and help support Arseblog by becoming an Arseblog Member on Patreon: https://www.patreon.com/arseblog

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Prime Day sees some pretty tempting deals and discounts on science gifts, but is it worth waiting for Black Friday to potentially save even more?

The post Black and White Portraits of Country Girls by Oleg Videnin appeared first on English Russia.

Two NASA telescopes helped an international team of astrophysicists peer far enough back in time to gain new insight on how black holes form.

Scientists have long known that magnetic fields probably extract energy from spinning black holes — they just didn’t know how.

“Chigumadzi argues that within the liberal international order, it is “reasonable” and “workable” to struggle to end apartheid and racial segregation, while it is “unreasonable” and “unworkable” to struggle to end settler colonialism and indigenous land dispossession. In arguing that apartheid is overrepresented in the International Left’s racial discourse and historiography, Chigumadzi draws from generations of Black South African political activists, philosophers, and historians—most notably from the Pan Africanist-Black Consciousness Tradition. These traditions critique apartheid’s relatively short 54 years of institutionalized racial segregation as the paradigmatic historical framework for analyzing South Africa’s three centuries of settler colonialism and land dispossession. Drawing from this black radical critique, Chigumadzi rejects the liberal notion that apartheid’s end is the object of liberation struggle, and, instead asserts the centrality of the struggle for the return of indigenous lands.” Dr. Panashe Chigumadzi is an award-winning writer and Assistant Professor of African History at Brandeis University. Chigumadzi holds a doctorate from Harvard University’s Department of African and African American Studies, and a masters in African Literature from the University of the Witwatersrand, Johannesburg, South Africa.

We are taking this opportunity to say Thank You! We can’t express how much we appreciate you being a part of RSS Ground family. We hope our unique tools will continue to be useful to you for years to come. We usually never do this, but this time we would like to show our token […]

The post Happy Thanksgiving and Black Friday Deal appeared first on RSSground.com.

Not everything that crosses a supermassive black hole’s accretion disc gets spaghettified, astrophysicists say.

The Event Horizon Telescope team has captured the first image of Sagittarius A*, the black hole at the center of the Milky Way.

The absolute number of Black men enrolled at Historically Black Colleges and Universities is the lowest it's been since 1976.

teaser here

The following article, Will Black Men Tolerate This Insult from Kamala Harris?, was first published on The Black Sphere.

Who is running the Harris-Walz campaign? Because if I had to guess, I'd say a 13 year-old white girl. Kamala Harris' campaign is watching voters jump ship reminiscent of the Titanic.

Continue reading Will Black Men Tolerate This Insult from Kamala Harris? ...

Blind comedian Chris McCausland and his dance partner performed part of the routine with the lights off.

How cheese has become so valuable that it's being stolen to order

Denzel Washington may have let slip that director Ryan Coogler is working on a third "Black Panther" film, which Marvel has not yet announced.

Ergatta's Black Friday deals are live now, giving shoppers a chance to save up to $850 on its smart rowers, including free shipping.

The best early Black Friday MacBook deals include all-time low prices on the latest MacBook Air models.

Black Friday is weeks away, but Amazon already has several great deals you can find now. Here are the best Amazon early Black Friday deals.

The collaboration comes amid skyrocketing demand for Nvidia chips, as companies scramble to secure supplies.

I met two debut authors at a summer conference and was taken with their warmth and earnestness. Their book, Black Boy, Black Boy, is an affirmation that celebrates both past accomplishments by Black men and the limitless possibilities for a child’s future. Their book is sure to encourage discussion with children and families, whether they are Black or not. Both authors graciously agreed to a blog interview.

Many fans of Huawei on Friday were disappointed that its much-anticipated phone, Mate XT - more than twice the price of the iPhone 16 Pro Max - was not available for walk-in customers.

The Springboks will continue to evolve their attack, but they must do so within the framework of what has made them so successful, says attack coach Tony Brown.

Celebrating Black History Month at Chatham House 24 October 2024 — 6:00PM TO 8:00PM Anonymous (not verified) 2 October 2024 Chatham House

Join us for the ‘Beyond expectations: The impact and legacy of migration exhibition 2024’ exhibition and drinks reception.

About the Photographer  

Neil Kenlock, a photographer and media professional, has lived in London since arriving from Jamaica in 1963 to join his parents. He spent the early years of his career as a professional photographer, specialising in fashion, beauty, celebrities, and the cultural lifestyles of Black people in the UK. In the late 1960s and 1970s, he captured images of the UK Black Panther movement and documented demonstrations and anti-racism protests across the country.

“Neil Kenlock helps us to better understand the story of London’s Black communities and to appreciate the huge artistic and cultural impact they have had on all our lives. He is a significant photographer whose work documents a key chapter in London’s post-war history.” — Mike Seaborne, former curator of photographs at the Museum of London.

About the exhibition

This exhibition unveils a collection of photographs by Neil Kenlock, capturing Black British individuals who migrated from their homelands and settled in the UK. Curated by his daughter Emelia Kenlock, the series explores the theme of ‘expectations’ and its enduring legacy, featuring African and Caribbean subjects who brought their skills, passions, and dreams—contributions that have profoundly shaped British culture today.

Reflecting on the work, Kenlock stated: “Over 50 years since the concept of ‘black excellence’ first manifested, and more than 70 years since the Windrush, I truly hope this exhibition will add to the national cultural narrative and resonate with new audiences.” 

HIV Type 1 (HIV-1) and simian immunodeficiency virus (SIV) display differential replication kinetics in macrophages. This is because high expression levels of the active host deoxynucleotide triphosphohydrolase sterile α motif domain and histidine-aspartate domain–containing protein 1 (SAMHD1) deplete intracellular dNTPs, which restrict HIV-1 reverse transcription, and result in a restrictive infection in this myeloid cell type. Some SIVs overcome SAMHD1 restriction using viral protein X (Vpx), a viral accessory protein that induces proteasomal degradation of SAMHD1, increasing cellular dNTP concentrations and enabling efficient proviral DNA synthesis. We previously reported that SAMHD1-noncounteracting lentiviruses may have evolved to harbor RT proteins that efficiently polymerize DNA, even at low dNTP concentrations, to circumvent SAMHD1 restriction. Here we investigated whether RTs from SIVmac239 virus lacking a Vpx protein evolve during in vivo infection to more efficiently synthesize DNA at the low dNTP concentrations found in macrophages. Sequence analysis of RTs cloned from Vpx (+) and Vpx (−) SIVmac239–infected animals revealed that Vpx (−) RTs contained more extensive mutations than Vpx (+) RTs. Although the amino acid substitutions were dispersed indiscriminately across the protein, steady-state and pre-steady-state analysis demonstrated that selected SIVmac239 Vpx (−) RTs are characterized by higher catalytic efficiency and incorporation efficiency values than RTs cloned from SIVmac239 Vpx (+) infections. Overall, this study supports the possibility that the loss of Vpx may generate in vivo SIVmac239 RT variants that can counteract the limited availability of dNTP substrate in macrophages.

G20's lack of progress highlights challenge for COP26 Expert comment NCapeling 1 November 2021

A positive outcome from the G20 summit was committing to end international financing for coal projects but, on other issues, the communique was ultimately weak.

Success at Glasgow depends on bridging fault lines

Renata Dwan

The G20 summit’s lack of progress on climate highlights the scale of the challenge – and the stakes – for COP26.  The countries responsible for 80 per cent of global emissions recognized but failed to agree concrete action to limit global warming to 1.5C.

The leaders’ gathering reveals multilateralism’s fault lines. One is the tension between domestic politics and international priorities, reflected in the lack of ambition to reduce coal dependency.  The second is the tension between industrialized and developing states over responsibility for delivering global goods.

The G20 failed to endorse the G7’s pledge to achieve net zero emissions by 2050 or to accelerate the mobilization of previously agreed climate financing. Success at Glasgow – and beyond – will depend on the extent to which these fault lines can be bridged.

Communique’s language was weak

Professor Tim Benton

A positive outcome on climate from the G20 summit was the commitment to end international financing for coal projects by the end of 2021. This is a win for the climate and for the G20-host, Italy.

The references to 1.5 degrees and the commitment to taking further action this decade were also important, and help lay the groundwork for COP26. On the downside, the communique’s language on phasing out fossil fuel subsidies and coal domestically was very weak.

The G20 summit should be regarded as the next step – it is crucial world leaders accelerate their efforts at COP26 in Glasgow to avert climate catastrophe and keep 1.5 degrees alive.

Platitudes and vague plans on pandemic preparedness

Robert Yates

As G20 leaders head to Glasgow to tackle the evolving climate crisis, they leave Rome having failed, yet again, to take serious action to end the ongoing COVID-19 crisis.

Despite the obvious urgency to achieve universal vaccine coverage, their communique contains little more than platitudes and vague plans to prepare better for future pandemics. It is not as if they had not been briefed. 

In the run up to the G20, the leaders of the WHO, WTO, IMF, World Bank, former world leaders, Nobel laureates and the Pope, all highlighted the costs of ongoing vaccine inequity: five million deaths next year and $5.3 trillion dollars in lost economic output by 2026.

The ask was also straightforward: launch a massive airlift of unneeded vaccines from rich countries through COVAX, ramp up financing of the multilateral response and accelerate technology transfers to developing countries.

But on all these issues the wording of the communique is weak, with no numbers on vaccines or funding, no hard timescales and no urgency. This does not augur well for the COP-26 summit.

G20 communique is a launching pad

Dr Leslie Vinjamuri

The G20 might seem disappointing to some, but a lot will depend on expectations. If your starting point is a pandemic that has so far taken five million lives and driven a global economic crisis, and that both these crises are marked by deep inequality, then the measures adopted are bound to look insufficient. But if your starting point is 16 years of democracy in decline, rampant disinformation on issues of climate and public health, four years of failed international leadership during the Donald Trump presidency and, especially today, heightened tensions between the US and China, the world’s two greatest powers, then the fact that the G20 communique achieved as much as it has is remarkable.

Any written document that requires agreement between the US, UK, China, Russia, India, Saudi Arabia and the EU is necessarily going to be watered down.

But the principles are in the document, and mostly everyone turned up – if some by video. That is a good outcome for this kind of multilateralism in 2021. The G20 communique is a floor not a ceiling, and it’s a launching pad for activism and mobilisation by individual states, but also by corporates, civil society, and subnational actors. 

Now we need to hope that those on the right side of progress, whether on climate, health, or development, will use this language to drive forward concrete actions towards net zero, climate finance, vaccine distribution, and debt relief.

Specifics are for the most part missing

Creon Butler

This year’s G20 leaders’ summit marks a stark contrast with the past four years when much of the group’s energy was exhausted simply trying to maintain a consensus – in the face of opposition by a President Trump-led United States – on such issues as the importance of tackling climate change, the benefits of the rules-based multilateral trade system and the centrality of the International Monetary Fund (IMF) in the global financial safety net. 

By contrast, today’s G20 Rome Leaders’ declaration early on underlines ‘the crucial role of multilateralism in finding shared, effective solutions’. In two critical areas for the world economy – the global boost to liquidity from the general allocation of $650bn in Special Drawing Rights and the global tax deal focused on addressing challenges arising from digitalisation – this outlook has been translated into very substantial and concrete achievements announced earlier in the year.

Algorithms can be very useful, but lately, with so much data being created and shared, and with the increase in their use in critical areas such as hiring, credit, and health care, algorithms are under intense scrutiny about their fairness. People experience the effects of an algorithm's conclusion, but the data and steps that form the basis for that conclusion are frequently hidden from them (as if inside a black box). Cathy O'Neil talks about the unfairness of most predictive algorithms.

When a scuba diver comes up from the deep too quickly, the rapid decrease in pressure can give them a case of "the bends" or decompression sickness. It is caused by bubbles of gas building up in the body, causing pain. It can also be fatal....

Mouse embryonic stem cells (mESCs) display unique mechanical properties, including low cellular stiffness in contrast to differentiated cells, which are stiffer. We have previously shown that mESCs lacking the clathrin heavy chain (Cltc), an essential component for clathrin-mediated endocytosis (CME), display a loss of pluripotency and an enhanced expression of differentiation markers. However, it is not known whether physical properties such as cellular stiffness also change upon loss of Cltc, similar to what is seen in differentiated cells, and if so, how these altered properties specifically impact pluripotency. Using atomic force microscopy (AFM), we demonstrate that mESCs lacking Cltc display higher Young's modulus, indicative of greater cellular stiffness, compared with WT mESCs. The increase in stiffness was accompanied by the presence of actin stress fibers and accumulation of the inactive, phosphorylated, actin-binding protein cofilin. Treatment of Cltc knockdown mESCs with actin polymerization inhibitors resulted in a decrease in the Young's modulus to values similar to those obtained with WT mESCs. However, a rescue in the expression profile of pluripotency factors was not obtained. Additionally, whereas WT mouse embryonic fibroblasts could be reprogrammed to a state of pluripotency, this was inhibited in the absence of Cltc. This indicates that the presence of active CME is essential for the pluripotency of embryonic stem cells. Additionally, whereas physical properties may serve as a simple readout of the cellular state, they may not always faithfully recapitulate the underlying molecular fate.

Aloïs Dusuel
Dec 9, 2020; 0:jlr.RA120000704v1-jlr.RA120000704
Research Articles

In SAS Retail Space Management, it should be possible to click on any location object, then Show Properties, and change the location fill color. This can be done on the gray-filled objects. However, w

Bacterial lipopolysaccharides (LPSs or endotoxins) can bind most proteins of the lipid transfer/LPS-binding protein (LT/LBP) family in host organisms. The LPS-bound LT/LBP proteins then trigger either an LPS-induced proinflammatory cascade or LPS binding to lipoproteins that are involved in endotoxin inactivation and detoxification. Cholesteryl ester transfer protein (CETP) is an LT/LBP member, but its impact on LPS metabolism and sepsis outcome is unclear. Here, we performed fluorescent LPS transfer assays to assess the ability of CETP to bind and transfer LPS. The effects of intravenous (iv) infusion of purified LPS or polymicrobial infection (cecal ligation and puncture [CLP]) were compared in transgenic mice expressing human CETP and wild-type mice naturally having no CETP activity. CETP displayed no LPS transfer activity in vitro, but it tended to reduce biliary excretion of LPS in vivo. The CETP expression in mice was associated with significantly lower basal plasma lipid levels and with higher mortality rates in both models of endotoxemia and sepsis. Furthermore, CETPTg plasma modified cytokine production of macrophages in vitro. In conclusion, despite having no direct LPS binding and transfer property, human CETP worsens sepsis outcomes in mice by altering the protective effects of plasma lipoproteins against endotoxemia, inflammation, and infection.