express

Variable protein expression in marine-derived filamentous fungus Penicillium chrysogenum in response to varying copper concentrations and salinity

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00316A, Paper
Nikita Lotlikar, Samir Damare, Ram Murti Meena, Saranya Jayachandran
Copper is one of the essential trace dietary minerals for all living organisms, but is potentially toxic at higher concentrations, mainly due to the redox reactions in its transition state.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




express

Gene expression in mouse muscle over time after nickel pellet implantation

Metallomics, 2020, 12,528-538
DOI: 10.1039/C9MT00289H, Paper
Desmond I. Bannon, Wenjun Bao, Stephen D. Turner, Wilfred C. McCain, William Dennis, Russ Wolfinger, Ed Perkins, Roger Abounader
Implanted nickel becomes toxic when it exceeds homeostasis, initiating a range of global gene effects over time, including oxidative phosphorylation and immune responses, which are impacted in opposite directions.
The content of this RSS Feed (c) The Royal Society of Chemistry




express

Science Podcast - Noisy gene expression, the Tohoku-oki fault, and snake venom as a healer (6 Dec 2013)

Discussing the origin of transcriptional noise with Alvaro Sanchez; examining results from a drilling expedition at the Tohoku-oki fault; and looking at the potential benefits of snake venom with Kai Kupferschmidt.




express

Government looking into possibility of building smart cities along Delhi-Mumbai Expressway: Nitin Gadkari

"The government is looking if NHAI can plan a township along the highway (Delhi-Mumbai Expressway) ... a Cabinet note has been floated for this," Road Transport, Highways and MSME Minister Gadkari said during an interaction with real estate body NAREDCO via a video conference.




express

Delhi-Amritsar-Katra Expressway to pass through Amritsar: Harsimrat Kaur Badal

Food processing industries minister Harsimrat Kaur Badal on Thursday said that one section of the Delhi-Amritsar-Katra Expressway would pass through Amritsar after being split into two at Kartarpur even as the other section would go through Gurdaspur to Katra.




express

[ASAP] Discovering New Lipidomic Features Using Cell Type Specific Fluorophore Expression to Provide Spatial and Biological Specificity in a Multimodal Workflow with MALDI Imaging Mass Spectrometry

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00446




express

Fire in Dibrugarh-Delhi Rajdhani Express pantry car, no casualties reported

At around 4.30 am, a fire broke out in the kitchen and engulfed the train.




express

JSJ 311: Securing Express Apps with Helmet.js with Evan Hahn

Panel:

  • Charles Max Wood

Special Guests: Evan Hahn

In this episode, the JavaScript Jabber panelists discuss securing Express apps with Helmet.js with Evan Hahn. Evan is a developer at Airtable, which is a company that builds spreadsheet applications that are powerful enough that you can make applications with. He has also worked at Braintree, which does payment processing for companies. They talk about what Helmet.js is, when you would want to use it, and why it can help secure your Express apps. They also touch on when you wouldn’t want to use Helmet and the biggest thing that it saves you from in your code.

In particular, we dive pretty deep on:

  • Evan intro
  • JavaScript
  • What is Helmet.js?
  • Node and Express
  • Why would you use the approach of Middleware?
  • Helmet is not the only solution
  • Http headers
  • Current maintainer of Helmet.js
  • npm
  • Has added a lot to the project, but is not the original creator
  • Outbound HTTP response headers
  • Helmet doesn’t fully secure your app but it does help secure it
  • How does using Helmet work?
  • Are there instances when you wouldn’t want to use Helmet?
  • No cash middleware
  • Where do you set the configuration options?
  • Top level Helmet module
  • 12 modules
  • What is the biggest thing that Helmet saves you from?
  • Content security policy code
  • And much, much more!

Links:

Picks:

Charles

Evan




express

A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression

RSC Adv., 2020, 10,17561-17570
DOI: 10.1039/D0RA02686G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Leroy Shervington, Oliver Ingham, Amal Shervington
The standard of care treatment for patients diagnosed with glioblastoma multiforme (GBM) is temozolomide (TMZ).
The content of this RSS Feed (c) The Royal Society of Chemistry




express

Better float containment in IE using CSS expressions

Research into improving the cross-browser consistency of both the “clearfix” and “overflow:hidden” methods of containing floats. The aim is to work around several bugs in IE6 and IE7.

This article introduces a new hack (with caveats) that can benefit the “clearfix” methods and the new block formatting context (NBFC) methods (e.g. using overflow:hidden) of containing floats. It’s one outcome of a collaboration between Nicolas Gallagher (that’s me) and Jonathan Neal.

If you are not familiar with the history and underlying principles behind methods of containing floats, I recommend that you have a read of Easy clearing (2004), Everything you know about clearfix is wrong (2010), and Clearfix reloaded and overflow:hidden demystified (2010).

Consistent float containment methods

The code is show below and documented in this GitHub gist. Found an improvement or flaw? Please fork the gist or leave a comment.

Micro clearfix hack: Firefox 3.5+, Safari 4+, Chrome, Opera 9+, IE 6+

.cf {
  /* for IE 6/7 */
  *zoom: expression(this.runtimeStyle.zoom="1", this.appendChild(document.createElement("br")).style.cssText="clear:both;font:0/0 serif");
  /* non-JS fallback */
  *zoom: 1;
}

.cf:before,
.cf:after {
  content: "";
  display: table;
}

.cf:after {
  clear: both;
}

Overflow hack (NBFC): Firefox 2+, Safari 2+, Chrome, Opera 9+, IE 6+

.nbfc {
  overflow: hidden;
  /* for IE 6/7 */
  *zoom: expression(this.runtimeStyle.zoom="1", this.appendChild(document.createElement("br")).style.cssText="clear:both;font:0/0 serif");
  /* non-JS fallback */
  *zoom: 1;
}

The GitHub gist also contains another variant of the clearfix method for modern browsers (based on Thierry Koblentz’s work). It provides greater visual consistency (avoiding edge-case bugs) for even older versions of Firefox.

The only difference from existing float-containment methods is the inclusion of a CSS expression that inserts a clearing line-break in IE 6 and IE 7. Jonathan and I found that it helps to resolve some of the visual rendering differences that exist between these browsers and more modern ones. First I’ll explain what some of those differences are and when they occur.

Containing floats in IE 6/7

In IE 6 and IE 7, the most common and robust method of containing floats within an element is to give it “layout” (find out more: On having Layout). Triggering “layout” on an element in IE 6/7 creates a new block formatting context (NBFC). However, certain IE bugs mean that previous float containment methods don’t result in cross-browser consistency. Specifically, this is what to expect in IE 6/7 when creating a NBFC:

  1. The top- and bottom-margins of non-floated child elements are contained within the ancestor element that has been given “layout”. (Also expected in other browsers when creating a NBFC)
  2. The bottom-margins of any right-floated descendants are contained within the ancestor. (Also expected in other browsers when creating a NBFC)
  3. The bottom-margins of any left-floated children are not contained within the ancestor. The margin has no effect on the height of the ancestor and is truncated, having no affect outside of the ancestor either. (IE 6/7 bug)
  4. In IE 6, if the right edge of the margin-box of a left-floated child is within 2px of the left edge of the content-box of its NBFC ancestor, the float’s bottom margin reappears and is contained within the parent. (IE 6 bug)
  5. Unwanted white-space can appear at the bottom of a float-container. (IE 6/7 bug)

There is a lack of consistency between IE 6/7 and other browsers, and between IE 6 and IE 7. Thanks to Matthew Lein for his comment that directed me to this IE 6/7 behaviour. It was also recently mentioned by “Suzy” in a comment on Perishable Press.

IE 6/7’s truncation of the bottom-margin of left-floats is not exposed in many of the test-cases used to demonstrate CSS float containment techniques. Using an IE-only CSS expression helps to correct this bug.

The CSS expression

Including the much maligned <br style="clear:both"> at the bottom of the float-container, as well as creating a NBFC, resolved all these inconsistencies in IE 6/7. Doing so prevents those browsers from collapsing (or truncating) top- and bottom-margins of descendant elements.

Jonathan suggested inserting the clearing line-break in IE 6/7 only, using CSS expressions applied to fictional CSS properties. The CSS expression is the result of many iterations, tests, and suggestions. It runs only once, the first time an element receives the associated classname.

*zoom: expression(this.runtimeStyle.zoom="1", this.appendChild(document.createElement("br")).style.cssText="clear:both;font:0/0 serif");

It is applied to zoom, which is already being used to help contain floats in IE 6/7, and the use of the runtimeStyle object ensures that the expression is replaced once it has been run. The addition of font:0/0 serif prevents the occasional appearance of white-space at the bottom of a float-container. And the * hack ensures that only IE 6 and IE 7 parse the rule.

It’s worth noting that IE 6 and IE 7 parse almost any string used as CSS property. An earlier iteration used the entirely fictitious properties “-ms-inject” or “-ie-x” property to exploit this IE behaviour.

*-ie-x: expression(this.x||(this.innerHTML+='&lt;br style="clear:both;font:0/0">',this.x=1));

However, this expression is evaluated over and over again. Using runtimeStyle instead avoids this. Sergey Chikuyonok also pointed out that using innerHTML destroys existing HTML elements that may event handlers attached to them. By using document.createElement and appendChild you can insert the new element without removing all the events attached to other descendant elements.

Containing floats in more modern browsers

There are two popular methods to contain floats in modern browsers. Creating a new block formatting context (as is done in IE 6/7 when hasLayout is triggered) or using a variant of the “clearfix” hack.

Creating a NBFC results in an element containing any floated children, and will prevent top- and bottom-margin collapse of non-floated children. When combined with the enhanced IE 6/7 containment method, it results in consistent cross-browser float containment.

The other method, known as “clearfix”, traditionally used a single :after pseudo-element to clear floats in a similar fashion to a structural, clearing HTML line-break. However, to prevent the top-margins of non-floats from collapsing into the margins of their float-containing ancestor, you also need to use the :before pseudo-element. This is the approach taken in Thierry Koblentz’s “clearfix reloaded”. In contemporary browsers, the micro clearfix hack is also suitable.

The method presented in this article should help improve the results of cross-browser float containment, whether you predominantly use “clearfix” or the NBFC method. The specific limitations of both the “clearfix” and various NBFC methods (as outlined in Thierry’s articles) remain.

Problems

Using a CSS expression to change the DOM in IE 6/7 creates problems of its own. Obviously, the DOM in IE 6/7 is now different to the DOM in other browsers. This affects any JavaScript DOM manipulation that may depend on :last-child or appending new children.

This is still an experimental work-in-progress that is primarily research-driven rather than seeking to become a practical snippet of production code. Any feedback, further testing, and further experimentation from others would be much appreciated.

Thanks to these people for contributing improvements: Jonathan Neal, Mathias Bynens, Sergey Chikuyonok, and Thierry Koblentz.




express

[ASAP] HMW-GS at <italic toggle="yes">Glu-B1</italic> Locus Affects Gluten Quality Possibly Regulated by the Expression of Nitrogen Metabolism Enzymes and Glutenin-Related Genes in Wheat

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.0c00820




express

[ASAP] Changes in microRNAs Expression Profile of Mimetic Aging Mice Treated with Melanin from <italic toggle="yes">Sepiella japonica</italic> Ink

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.0c00291




express

[ASAP] New Findings in the Amino Acid Profile and Gene Expression in Contrasting Durum Wheat Gluten Strength Genotypes during Grain Filling

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.9b07842




express

Trauma and expressive arts therapy [electronic resource] : brain, body, and imagination in the healing process / Cathy A. Malchiodi.

New York : The Guilford Press, [2020]




express

Cloning, expression and comparison of the properties of Scy p 9, a Scylla paramamosain allergen

Food Funct., 2020, 11,3006-3019
DOI: 10.1039/D0FO00004C, Paper
Xin-Rong He, Yi-Meng Cheng, Yang Yang, Jie-Jing Xie, Ka-Hou Chu, Yong-Xia Zhang, Gui-Xia Chen, Hong Liu, Min-Jie Cao, Guang-Ming Liu
This study investigated the properties of Scy p 9 in mud crab (Scylla paramamosain).
The content of this RSS Feed (c) The Royal Society of Chemistry




express

The impact of oligosaccharide content, glycosidic linkages and lactose content of galacto-oligosaccharides (GOS) on the expression of mucus-related genes in goblet cells

Food Funct., 2020, 11,3506-3515
DOI: 10.1039/D0FO00064G, Paper
Susana Figueroa-Lozano, Chengcheng Ren, Huifang Yin, Hien Pham, Sander van Leeuwen, Lubbert Dijkhuizen, Paul de Vos
Galacto-oligosaccharides (GOS) are molecules known to impact goblet cell function and mucus composition. Our results show that their molecular structure have a direct effect on goblet cells and impact mucus synthesis-related genes.
The content of this RSS Feed (c) The Royal Society of Chemistry




express

Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




express

[ASAP] Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01022




express

From single to a dual-gene delivery nanosystem: coordinated expression matters for boosting the neovascularization in vivo

Biomater. Sci., 2020, 8,2318-2328
DOI: 10.1039/C9BM02000D, Paper
Bin Gao, Xiaoyu Wang, Meiyu Wang, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang, Yakai Feng
A dual-gene delivery system with coordinated expression function boosted the neovascularization.
The content of this RSS Feed (c) The Royal Society of Chemistry




express

Betty in coat and hat, standing with doll in wagon marked "press" (express?) outside house with brick porch




express

Florida East Coast Railroad, Key West Extension, Key West Express entering Long Key Viaduct, Florida




express

Detection and quantification of Karenia brevis using carbon fixation gene expression analysis




express

Cloning, expression, and sequence analysis of camelysin, a zinc metalloprotease from bacillus anthracis and b. cereus




express

Role of stat3 in regulating hif-1alpha expression and tumor angiogenesis




express

The effect of conducting gesture on expressive-interpretive performance of college music majors




express

Use of random subspace ensembles on gene expression profiles to enhance the accuracy of survival prediction for colon cancer patients




express

Gene expression profiles and clinical parameters for survival prediction in stage II and III colorectal cancer




express

Electrogenetherapy of established B16 murine melanoma by using an expression plasmid for HIV-1 viral protein R




express

The use of microarrays in the detection of the gene expression of ribulose- 1,5- bisphosphate carboxylase/oxygenase in the marine environment




express

BRCA1 185delAG mutant protein, BRAt, amplifies caspase-mediated apoptosis and maspin expression in ovarian cells




express

Relationship of anger trait and anger expression to c-reactive protein in post-menopausal women




express

Florida expressways and the public works career of Congressman William C. Cramer




express

Influence of temporary inactivation of the prefrontal cortex of hippocampus during stress on the subsequent expression of anxiety and memory




express

Characterization of cannabinoid receptor 2 transcript expression in b cells




express

Microexpression spotting in video using optical strain




express

Enhancing gene expression signatures in cancer prediction models :




express

Gender and cocaine use influence the expression of urinary markers of inflammation and oxidative stress




express

Analysis of ahr expression and stability in a recombinant yeast model system




express

A Fruit Growers Express railroad car out west




express

[A Florida Highway Express, Inc. truck]




express

[A Florida Highway Express, Inc. truck getting fueled]




express

Economic and mobility impacts of the Orlando Orange County Expressway Authority




express

Status review and future role of the Tampa-Hillsborough County Expressway Authority




express

Population abundance, sexual expression, and gender ratios of Marchantia sp. along an elevational gradient in Monteverde, Costa Rica




express

The development of a method to measure microbial gene expression in the marine water-column environment




express

Diel rhythms in rubisco gene expression in cyanophytic and chromophytic clades of cultured and natural populations of phytoplankton




express

Corneal Neo-vascularization and VEGF Expression in Pinnipeds




express

Buffalo Bill's saddle sharps; or, The pledged pards of the Pony Express




express

Young Klondike's ice boat express, or, The golden cave on the glacier




express

Young Wild West's pony express, or, Getting the mail through on time