1 Danish Krone = 0.5338 United Arab Emirates Dirham

1 Fiji Dollar = 1.6303 United Arab Emirates Dirham

1 New Zealand Dollar = 2.2546 United Arab Emirates Dirham

1 Croatian Kuna = 0.5294 United Arab Emirates Dirham

1 Peruvian Nuevo Sol = 1.0806 United Arab Emirates Dirham

1 Dominican Peso = 0.0667 United Arab Emirates Dirham

1 Papua New Guinean Kina = 1.0708 United Arab Emirates Dirham

1 Brunei Dollar = 2.5991 United Arab Emirates Dirham

Do you have a set of Bluetooth earbuds yet? If not, you will. The iPhone was the first to kill the ubiquitous 3.5mm headphone jack, but many other manufacturers have quietly followed. Of course,...

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visit News18 Urdu for latest news, breaking news, news headlines and updates from Barabanki on politics, sports, entertainment, cricket, crime and more.

Saudi Arabia, the world’s biggest oil exporter, is poised to start generating wind power within three years as part of an effort to harness renewable energy to cut local demand for fossil fuels.

Saudi Arabia, the world’s biggest oil exporter, is poised to start generating wind power within three years as part of an effort to harness renewable energy to cut local demand for fossil fuels.

Saudi Arabia, the world’s biggest oil exporter, is poised to start generating wind power within three years as part of an effort to harness renewable energy to cut local demand for fossil fuels.

Saudi Arabia, the world’s biggest oil exporter, is poised to start generating wind power within three years as part of an effort to harness renewable energy to cut local demand for fossil fuels.

Introduction to Abu Dhabi Global Market – Employment Regulations In 2013 the Abu Dhabi Global Market (“ADGM”) was established as a financial free zone in Abu Dhabi, UAE. Since then, the ADGM has implemented its own rules and regul...

UAE employers be aware - new UAE employment requirementsThree new Ministerial Decrees came into effect on 1 January 2016. These Decrees, issued by the Ministry of Labour (“MOL”), impact upon the way job offers are made and have implicati...

Ministry of Labour makes numerous labour law changes The Ministry of Labour made a number of changes to labour law with effect from 18 October 2015. Amongst other things, the amendments cover disciplinary procedures, training, Saudization privileges...

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

On 20 June 2019, the UK Court of Appeal ruled that the UK Government’s decision to continue licensing exports of military equipment to Saudi Arabia for possible use in the conflict in Yemen was unlawful. The judgment comes amidst global concer...

Background On 9 January 2020, REPDO invited developers to prequalify via a request for qualifications (“RfQ”) for the third round of the NREP in the Kingdom of Saudi Arabia. Third round of the NREP There will be four photovoltaic (&ldquo...

The U.S. is pulling two Patriot missile batteries and some fighter aircraft out of Saudi Arabia, an American official said on May 7, amid tensions between the kingdom and the Trump administration over oil production.

From exotic animals to spectacles and chandeliers, Michael Laver’s “The Dutch East India Company in Early Modern Japan” shows how well-placed gifts were essential in ...

A weekly selection of opinions and analyses from the Arab media around the world.

The country's Interior Ministry also announced a new round of hefty fines for quarantine violators.

The Pentagon is set to pull Patriot missile defense systems from Saudi Arabia amid internal pressure to transfer military assets to counter China.

WASHINGTON: The US is pulling out four of its powerful Patriot missile systems from Saudi Arabia, after determining the threat from Iran that sparked an arms buildup in the region last year had waned, a Defense Department official said Thursday. Two of the anti-missile batteries deployed following...

WASHINGTON: The US is pulling out four of its powerful Patriot missile systems from Saudi Arabia, after determining the threat from Iran that sparked an arms buildup in the region last year had waned, a Defence Department official said late on Thursday.Two of the anti-missile batteries deployed...

Human Rights Watch (HRW) said on Saturday that Saudi Arabian authorities recently detained and are holding incommunicado Prince Faisal bin Abdullah, who had previously been netted in an anti-corruption drive and released in late 2017.

The US-based rights group, citing a source with ties to the royal family, said Prince Faisal bin Abdullah, a son of late monarch King Abdullah, was detained by security forces on March 27 while self-isolating due to the coronavirus pandemic at a family compound northeast of the capital Riyadh.

Reuters could not immediately independently verify the detention. The Saudi government media office did not immediately respond to a detailed Reuters request for comment.

Earlier in March, authorities had detained King Salman’s brother, Prince Ahmed bin Abdulaziz, and former crown prince Mohammed bin Nayef, who was replaced in a 2017 palace coup and placed under house arrest, sources had told Reuters.

Sources with royal connections said at the time that the move was a preemptive effort to ensure compliance within the ruling Al Saud family ahead of an eventual succession to the throne by Crown Prince Mohammed bin Salman upon the king’s death or abdication.

It was not clear if the reported detention of Prince Faisal was related to those in early March, which also saw Ahmed’s son Nayef and Mohammed bin Nayef’s brother Nawaf detained.

Saudi authorities have not commented on those detentions, which follow crackdowns on dissent in which clerics, intellectuals and rights activists have been arrested, and an anti-corruption drive launched in 2017 that netted scores of royals, ministers and businessmen.

Critics have said the campaigns were part of moves by Crown Prince Mohammed, the king’s son and the kingdom’s de facto ruler, to consolidate his grip on power.

“Now we have to add Prince Faisal to the hundreds detained in Saudi Arabia without a clear legal basis,” said Michael Page, deputy Middle East director at HRW.

The kingdom has regularly denied allegations of unfair detention.

Authorities said last year the government was winding down the anti-corruption campaign after 15 months, but would continue to go after graft.

HRW said Prince Faisal’s whereabouts or status are not known.

“The source said that Prince Faisal has not publicly criticised authorities since his December 2017 arrest and that family members are concerned about his health as he has a heart condition,” it added.

In late December 2017, a senior Saudi official said Prince Faisal and another royal, Prince Meshaal bin Abdullah, were released from Riyadh’s Ritz-Carlton hotel, where people nabbed in the anti-corruption drive were being held, after reaching an undisclosed financial settlement with the government.

The number of coronavirus cases in Saudi Arabia exceeded 35,000 on Friday as the kingdom struggles to get to grips with rising numbers of new infections.

President Donald Trump and Saudi Arabia's King Salman spoke by phone Friday and "reaffirmed the strong United States-Saudi defense partnership," the White House said, amid tensions over Saudi's oil output.

Genetic analysis suggests all Arabica coffee plants are descended from a single common ancestor, and this lack of genetic diversity makes them vulnerable to extinction

Human Rights Watch (HRW) said on Saturday that Saudi Arabian authorities recently detained and are holding incommunicado Prince Faisal bin Abdullah, who had previously been netted in an anti-corruption drive and released in late 2017.

Title: Vyxeos (daunorubicin and cytarabine)
Category: Medications
Created: 4/24/2020 12:00:00 AM
Last Editorial Review: 4/24/2020 12:00:00 AM

In plants, water use efficiency (WUE) is a complex trait arising from numerous physiological and developmental characteristics. Here, we investigated the involvement of circadian regulation in long-term WUE in Arabidopsis (Arabidopsis thaliana) under light and dark conditions. Circadian rhythms are generated by the circadian oscillator, which provides a cellular measure of the time of day. In plants, the circadian oscillator contributes to the regulation of many aspects of physiology, including stomatal opening, rate of photosynthesis, carbohydrate metabolism, and developmental processes such as the initiation of flowering. We investigated the impact of the misregulation of numerous genes encoding various components of the circadian oscillator on whole plant, long-term WUE. From this analysis, we identified a role for the circadian oscillator in WUE. It appears that the circadian clock contributes to the control of transpiration and biomass accumulation. We also established that the circadian oscillator within guard cells can contribute to long-term WUE. Our experiments indicate that knowledge of circadian regulation will be important for developing crops with improved WUE.

The selection and firing of DNA replication origins play key roles in ensuring that eukaryotes accurately replicate their genomes. This process is not well documented in plants due in large measure to difficulties in working with plant systems. We developed a new functional assay to label and map very early replicating loci that must, by definition, include at least a subset of replication origins. Arabidopsis (Arabidopsis thaliana) cells were briefly labeled with 5-ethynyl-2'-deoxy-uridine, and nuclei were subjected to two-parameter flow sorting. We identified more than 5500 loci as initiation regions (IRs), the first regions to replicate in very early S phase. These were classified as strong or weak IRs based on the strength of their replication signals. Strong initiation regions were evenly spaced along chromosomal arms and depleted in centromeres, while weak initiation regions were enriched in centromeric regions. IRs are AT-rich sequences flanked by more GC-rich regions and located predominantly in intergenic regions. Nuclease sensitivity assays indicated that IRs are associated with accessible chromatin. Based on these observations, initiation of plant DNA replication shows some similarity to, but is also distinct from, initiation in other well-studied eukaryotic systems.

Photorespiration is an essential process in oxygenic photosynthetic organisms triggered by the oxygenase activity of Rubisco. In peroxisomes, photorespiratory HYDROXYPYRUVATE REDUCTASE1 (HPR1) catalyzes the conversion of hydroxypyruvate to glycerate together with the oxidation of a pyridine nucleotide cofactor. HPR1 regulation remains poorly understood; however, HPR1 phosphorylation at T335 has been reported. By comparing the kinetic properties of phosphomimetic (T335D), nonphosphorylatable (T335A), and wild-type recombinant Arabidopsis (Arabidopsis thaliana) HPR1, it was found that HPR1-T335D exhibits reduced NADH-dependent hydroxypyruvate reductase activity while showing improved NADPH-dependent activity. Complementation of the Arabidopsis hpr1-1 mutant by either wild-type HPR1 or HPR1-T335A fully complemented the photorespiratory growth phenotype of hpr1-1 in ambient air, whereas HPR1-T335D-containing hpr1-1 plants remained smaller and had lower photosynthetic CO₂ assimilation rates. Metabolite analyses indicated that these phenotypes were associated with subtle perturbations in the photorespiratory cycle of HPR1-T335D-complemented hpr1-1 rosettes compared to all other HPR1-containing lines. Therefore, T335 phosphorylation may play a role in the regulation of HPR1 activity in planta, although it was not required for growth under ambient air controlled conditions. Furthermore, improved NADP-dependent HPR1 activities in peroxisomes could not compensate for the reduced NADH-dependent HPR1 activity.

Phosphatidylcholine and phosphatidylethanolamine are two major phospholipid classes in eukaryotes. Each biosynthesis pathway starts with the phosphorylation of choline (Cho) or ethanolamine (Etn) catalyzed by either choline or ethanolamine kinase (CEK). Arabidopsis contains four CEK isoforms, but their isozyme-specific roles in metabolism and development are poorly described. Here, we showed that these four CEKs have distinct substrate specificities in vitro. While CEK1 and CEK2 showed substrate preference for Cho over Etn, CEK3 and CEK4 had clear substrate specificity for Cho and Etn, respectively. In vivo, CEK1, CEK2, and CEK3 exhibited kinase activity for Cho but not Etn, although the latter two isoforms showed rather minor contributions to total Cho kinase activity in both shoots and roots. The knockout mutants of CEK2 and CEK3 both affected root growth, and these isoforms had nonoverlapping cell-type-specific expression patterns in the root meristematic zone. In-depth phenotype analysis, as well as chemical and genetic complementation, revealed that CEK3, a Cho-specific kinase, is involved in cell elongation during root development. Phylogenetic analysis of CEK orthologs in Brassicaceae species showed evolutionary divergence between Etn kinases and Cho kinases. Collectively, our results demonstrate the distinct roles of the four CEK isoforms in Cho/Etn metabolism and plant development.

In plant–pathogen relations, disease symptoms arise from the interaction of the host and pathogen genomes. Host–pathogen functional gene interactions are well described, whereas little is known about how the pathogen genetic variation modulates both organisms’ transcriptomes. To model and generate hypotheses on a generalist pathogen control of gene expression regulation, we used the Arabidopsis thaliana–Botrytis cinerea pathosystem and the genetic diversity of a collection of 96 B. cinerea isolates. We performed expression-based genome-wide association (eGWA) for each of 23,947 measurable transcripts in Arabidopsis (host), and 9267 measurable transcripts in B. cinerea (pathogen). Unlike other eGWA studies, we detected a relative absence of locally acting expression quantitative trait loci (cis-eQTL), partly caused by structural variants and allelic heterogeneity hindering their identification. This study identified several distantly acting trans-eQTL linked to eQTL hotspots dispersed across Botrytis genome that altered only Botrytis transcripts, only Arabidopsis transcripts, or transcripts from both species. Gene membership in the trans-eQTL hotspots suggests links between gene expression regulation and both known and novel virulence mechanisms in this pathosystem. Genes annotated to these hotspots provide potential targets for blocking manipulation of the host response by this ubiquitous generalist necrotrophic pathogen.

The most fundamental genetic program of an annual plant defines when to grow and reproduce and when to remain dormant in the soil as a seed. With the right timing, plants can even live in hostile regions with only a few months of growth-favorable abundant rains and mild temperatures. To...

In Arabidopsis, LTR retrotransposons are activated by mutations in the chromatin gene DECREASE in DNA METHYLATION 1 (DDM1), giving rise to 21- to 22-nt epigenetically activated siRNA (easiRNA) that depend on RNA DEPENDENT RNA POLYMERASE 6 (RDR6). We purified virus-like particles (VLPs) from ddm1 and ddm1rdr6 mutants in which genomic RNA is reverse transcribed into complementary DNA. High-throughput short-read and long-read sequencing of VLP DNA (VLP DNA-seq) revealed a comprehensive catalog of active LTR retrotransposons without the need for mapping transposition, as well as independent of genomic copy number. Linear replication intermediates of the functionally intact COPIA element EVADE revealed multiple central polypurine tracts (cPPTs), a feature shared with HIV in which cPPTs promote nuclear localization. For one member of the ATCOPIA52 subfamily (SISYPHUS), cPPT intermediates were not observed, but abundant circular DNA indicated transposon "suicide" by auto-integration within the VLP. easiRNA targeted EVADE genomic RNA, polysome association of GYPSY (ATHILA) subgenomic RNA, and transcription via histone H3 lysine-9 dimethylation. VLP DNA-seq provides a comprehensive landscape of LTR retrotransposons and their control at transcriptional, post-transcriptional, and reverse transcriptional levels.

An exceptionally well-preserved specimen of the articulated rhodophyte Permocalculus, compared with P. tenellus sensu Elliott, 1955, is described from fine-grained Upper Permian limestones of the Khuff Formation of Saudi Arabia. Longitudinal medullary and sheaf-like cortical filaments extend through the uniserial series of elongate-globular, concave- and convex-terminating, interlocking segments for which they are interpreted to have functioned in articulation. The filaments tend to splay and branch laterally into the cortex where they terminate at the pores. At the terminal aperture, the filaments extend as bifurcating and possibly trifurcating branches and may serve as the origin of a new segment. Numerous elongate-globular chambers, up to five in each row and intimately involved with the filaments, are developed in the outer medulla and are considered to represent reproductive sporangia. The specimen is considered to have occupied predominantly low-energy, normal to slightly elevated salinity, shallow conditions within the subtidal regime of a lagoon.

Your weekly selection of awesome robot videos

Tributes have been paid to Ken and Betty Hill, who were together for more than 40 years

A huge blaze broke out at a 48-storey skyscraper in the United Arab Emirates city of Sharjah.

Sahirr Sethhi’s short film 'Zoya' spotlights wildlife conservation and man's disconnect with nature

Not once, but twice