In the Columbus City Schools, Ohio's largest school district, 62% of students have the required technology to learn online. The district is not alone. Schools around the state are on the hunt for online resources to close the gap -- and turning to corporate America and the public for help.

CapitaSearch browser hijacker removal instructions

What is CapitaSearch?

CapitaSearch is a piece of software, classified as a browser hijacker. Following successful infiltration, it modifies browser settings in order to promote search.capita.space - a fake search engine. Additionally, CapitaSearch adds the "Managed by your organization" feature to Google Chrome browsers. Most browser hijackers spy on browsing activity. Since most users download/install CapitaSearch unintentionally, it is also considered to be a PUA (Potentially Unwanted Application). One of the dubious methods used to distribute CapitaSearch is via illegal software activation ("cracking") tools. It is noteworthy that these tools are often used to proliferate malicious content as well (e.g. ransomware, trojans and other malware).

From a friend: Please explain to me your enthusiasm for controlled digital lending. Please let me know what you think...

Hibiscus tea mixed with tequila, lime, jalapeno, and pineapple makes this one delicious cocktail!

craving more? check out TasteSpotting

With Internet marketing and Search engine optimization, crucial components to owning a company site, most web designers are adding SEO to their arsenal of capabilities. The concern is that most of these designers neglect to understand the whole picture of… Continue Reading →

Chronic pancreatitis (CP) is considered an irreversible fibroinflammatory pancreatic disease. Despite numerous animal model studies, questions remain about local immune characteristics in human CP. We profiled pancreatic immune cell characteristics in control organ donors and CP patients including those with hereditary and idiopathic CP undergoing total pancreatectomy with islet autotransplantation. Flow cytometric analysis revealed a significant increase in the frequency of CD68+ macrophages in idiopathic CP. In contrast, hereditary CP samples showed a significant increase in CD3+ T cell frequency, which prompted us to investigate the T cell receptor β (TCRβ) repertoire in the CP and control groups. TCRβ sequencing revealed a significant increase in TCRβ repertoire diversity and reduced clonality in both CP groups versus controls. Interestingly, we observed differences in Vβ-Jβ gene family usage between hereditary and idiopathic CP and a positive correlation of TCRβ rearrangements with disease severity scores. Immunophenotyping analyses in hereditary and idiopathic CP pancreases indicate differences in innate and adaptive immune responses, which highlights differences in immunopathogenic mechanisms of disease among subtypes of CP. TCR repertoire analysis further suggests a role for specific T cell responses in hereditary versus idiopathic CP pathogenesis, providing insights into immune responses associated with human CP.

Fibroblasts are key effector cells in tissue remodeling. They remain persistently activated in fibrotic diseases, resulting in progressive deposition of extracellular matrix. Although fibroblast activation may be initiated by external factors, prolonged activation can induce an “autonomous,” self-maintaining profibrotic phenotype in fibroblasts. Accumulating evidence suggests that epigenetic alterations play a central role in establishing this persistently activated pathologic phenotype of fibroblasts. We demonstrated that in fibrotic skin of patients with systemic sclerosis (SSc), a prototypical idiopathic fibrotic disease, TGF-β induced the expression of DNA methyltransferase 3A (DNMT3A) and DNMT1 in fibroblasts in a SMAD-dependent manner to silence the expression of suppressor of cytokine signaling 3 (SOCS3) by promoter hypermethylation. Downregulation of SOCS3 facilitated activation of STAT3 to promote fibroblast-to-myofibroblast transition, collagen release, and fibrosis in vitro and in vivo. Reestablishment of the epigenetic control of STAT3 signaling by genetic or pharmacological inactivation of DNMT3A reversed the activated phenotype of SSc fibroblasts in tissue culture, inhibited TGF-β–dependent fibroblast activation, and ameliorated experimental fibrosis in murine models. These findings identify a pathway of epigenetic imprinting of fibroblasts in fibrotic disease with translational implications for the development of targeted therapies in fibrotic diseases.

Seizures often herald the clinical appearance of gliomas or appear at later stages. Dissecting their precise evolution and cellular pathogenesis in brain malignancies could inform the development of staged therapies for these highly pharmaco-resistant epilepsies. Studies in immunodeficient xenograft models have identified local interneuron loss and excess glial glutamate release as chief contributors to network disinhibition, but how hyperexcitability in the peritumoral microenvironment evolves in an immunocompetent brain is unclear. We generated gliomas in WT mice via in utero deletion of key tumor suppressor genes and serially monitored cortical epileptogenesis during tumor infiltration with in vivo electrophysiology and GCAMP7 calcium imaging, revealing a reproducible progression from hyperexcitability to convulsive seizures. Long before seizures, coincident with loss of inhibitory cells and their protective scaffolding, gain of glial glutamate antiporter xCT expression, and reactive astrocytosis, we detected local Iba1+ microglial inflammation that intensified and later extended far beyond tumor boundaries. Hitherto unrecognized episodes of cortical spreading depolarization that arose frequently from the peritumoral region may provide a mechanism for transient neurological deficits. Early blockade of glial xCT activity inhibited later seizures, and genomic reduction of host brain excitability by deleting MapT suppressed molecular markers of epileptogenesis and seizures. Our studies confirmed xenograft tumor–driven pathobiology and revealed early and late components of tumor-related epileptogenesis in a genetically tractable, immunocompetent mouse model of glioma, allowing the complex dissection of tumor versus host pathogenic seizure mechanisms.

Erowid Exp113948

"And you know, we have to stop looking beyond this election cycle and see that this corporate driven ideology, you know, this commodification of the culture, this constant extracting of blood from us as citizens to pay what in essence were private debts of the banks which engaged in casino capitalism, has political consequences. History has taught us that. And Hillary Clinton is only going to further that process." Continue reading →

The DNC is a one big capitalistic gangbang of Democrats and corporate donors and lobbyists. Guess who is getting screwed? Continue reading →

NITA STRAUSS в недавней беседе с Heavy New York рассказала о том, как продвигается работа над новым диском, выход которого намечен на этот год:

«Я бы не сказала, что новая пластинка будет принципиально отличаться от прошлого релиза. Это будет всё такой же инструментальный альбом, только я в неё вложила много разных граней своей личности, которых и так было не мало на "Controlled Chaos", но здесь они ярче и в плане агрессивной стороны, и в плане светлой и весёлой сторон, и более мирной и спокойной... Я буквально на прошлой неделе закончила работу над балладой, и я очень горжусь тем, какой она получилась. Так что тут определённо будет большой спектр самых разных эмоций. И самым большим вызовом для меня будет приглашение одного или даже двух вокалистов для нескольких тем. Так что это и будет самым большим отличием от первой работы». #Nita_Strauss #NitaStrauss

IBM today announced that Faurecia, one of the world’s leading automotive suppliers, has selected IBM Cloud as a support of a major business transformation designed to accelerate digital manufacturing.

Pets at Home, the UK’s leading pet specialist retailer and IBM today announced the launch of Sales Assist, an IBM MobileFirst for iOS app for iPad which will be used across 440 stores nationwide to make it easier and simpler for customers to purchase the products they need.

Today IBM and Eurobank announced the first cloud-based digital platform for online international commercial trading. Using IBM's industry-leading Digital Experience software, with advanced cloud capabilities and social offerings, Eurobank is uniting exporters and importers from around the globe to enhance international trade operations and increase transactions.

IBM today announced the opening of IBM Studio Groningen, where IBM design, digital and industry experts will work with clients to help them engage with their customers using big data, mobile, cloud and social innovations.

why am I helping to pay so much for the U.S. Military? I don't own anything.

[Image: An example of gravitational lens effects, via Wikipedia.] Over at WIRED, Daniel Oberhaus, author of the recent book Extraterrestrial Languages, takes a look at some proposals from NASA’s Innovative Advanced Concept (NIAC) program. “Among this year’s NIAC grants,” Oberhaus writes, “are proposals to turn a lunar crater into a giant radio dish, to develop … Continue reading "Gravitational Lensing, Interstellar Cinematography, and the Future of Magical Warfare in Space"

[Image: From a project called “Slice” by HANNAH, as featured in FABRICATE 2020.] The Bartlett School of Architecture recently put out two new books, freely available for download, FABRICATE 2020 and Design Transactions. Check them both out, as each is filled with incredibly interesting and innovative work. Purely in the interests of time—by all means, … Continue reading "Building Digital with Timber, Mud, and Ice"

IBM today announced its intention to acquire Vivant Digital business (Vivant), a boutique digital and innovation agency based here. This acquisition extends the strategy and design expertise of IBM iX, one of the world’s largest digital agencies and global business design partners, with Vivant talent and expertise to accelerate clients’ digital transformations.

As businesses increasingly recognize the opportunity to increase productivity, improve customer experiences and deliver new products and services through intelligent automation, Blue Prism and IBM have joined forces to deliver a secure, scalable and easy-to-use Digital Workforce for enterprises worldwide, such as Walgreens.

IBM Watson Health™ today published its 100 Top Hospitals® annual study identifying top–performing hospitals in the U.S. based on overall organizational performance. Formerly known as the Truven Health Analytics® 100 Top Hospitals, this study spotlights the best–performing hospitals in the U.S. based on a balanced scorecard of publicly available clinical, operational, and patient satisfaction metrics and data. It has been conducted annually since 1993.

IBM today announced it has completed the acquisition of Vivant Digital business (Vivant), a boutique digital and innovation agency based in Australia, to join IBM iX. Financial details were not disclosed.

El actual entorno tecnológico impulsa a las empresas a transformar sus modelos de negocio en un escenario en donde, según la Organización para la Cooperación y el Desarrollo Económicos (OCDE), el 25% de la economía mundial será digital en los próximos cinco años. De esta forma, el uso de nuevas tecnologías se vuelve la pieza clave para asegurar tanto competitividad, como su alto desempeño.

Como parte de su compromiso por contribuir con la tecnología más innovadora a la resolución de los desafíos y retos que enfrenta el mundo, IBM dio a conocer que seleccionó a CUCEA (Centro Universitario de Ciencias Económico y Administrativas) de la Universidad de Guadalajara (UdeG); a fin de poner en marcha en México la implementación del Programa IBM Skills Academy, con foco en competencias de tecnología de Nube.

IBM today announced that Westpac New Zealand, part of one of the world’s largest financial services institutions, has selected IBM’s private cloud technology to support its goal to be New Zealand’s leading digital bank. The new five year agreement is part of an extensive services and technology contract which includes Westpac migrating some of its business critical IT systems into IBM’s state-of-the-art Auckland data centre, enabling enhanced customer service.

At the Smarter Cities Forum in Shanghai today, IBM announced a collaboration with South China's largest hospital, Guang Dong Hospital of Traditional Chinese Medicine, to apply new analytics technology to help doctors uncover trends and new knowledge about disease treatment from thousands of anonymous Electronic Medical Records (EMR)The tool will also enable clinicians to perform empirical studies on the efficacy of certain traditional Chinese treatments.

Diltex -empresa mexicana propietaria de las marcas Ilusión y Fiorentina, socios de Vanity Fair Brands y franquiciatarios de David's Bridal en México- e IBM, anunciaron que la compañía dedicada a la industria de la moda está mejorando la experiencia del cliente y fortaleciendo su producción, distribución y comercialización a través de su transformación digital.

Unitec today announced that the number of people employed in two Delivery Centres at its Mount Albert campus now exceeds 500, and continue to drive benefits for Unitec students and the Auckland economy.

CEMEX, S.A.B. de C.V. (BMV: CEMEXCPO), una de las compañías de materiales para la industria de la construcción líder en el mundo, e IBM (NYSE: IBM) anunciaron hoy que CEMEX llevará a cabo una importante transformación tecnológica diseñada para optimizar sus operaciones, mejorar notablemente la experiencia de sus clientes y aumentar la eficiencia del negocio.

La progresiva digitalización de nuestra sociedad está provocando en las empresas la necesidad de transformarse para sacar el máximo partido de este fenómeno. Esta digitalización procede, principalmente, de la popularización de los dispositivos móviles inteligentes, las redes sociales y el Internet de las Cosas, que generan cada día 2,500 millones de gigabytes de datos. Dentro de toda esta información se esconde un inmenso valor para las organizaciones.

Durante la cumbre Business Connect 2017 en la Ciudad de México, IBM presentó a la Transformación Digital como una de las áreas de mayor crecimiento para los negocios en 2017 y mostró cómo las soluciones cognitivas (de analítica avanzada, de nube, de engagement), están transformando la forma en la que trabajamos y vivimos.

Habilita IBM el Crecimiento de las Organizaciones en una Era más Inteligente

El Tecnológico de Monterrey e IBM en México abrieron hoy el Innovation & Digital Marketing Center en el Campus Santa Fe de esta institución, un espacio único en su tipo en Latinoamérica que ofrecerá a la comunidad universitaria y a los emprendedores herramientas de Analítica y Smarter Marketing.

Vodafone New Zealand, a leading telecommunications services provider, and IBM (NYSE: IBM) today announced a partnership to deliver the Digital Vodafone 2021 program in New Zealand. The vision for Digital Vodafone 2021 is to create the most engaging digital customer experience by adopting agile as a way of working, embracing new technologies and simplifying business models. The program is supported by IBM iX, one of the world’s largest digital agencies and global business design partners.

A l’occasion du CES de Las Vegas, IBM annonce le lancement d’Advertising Accelerator with Watson, une solution unique de prédiction d’audiences pour annonceurs.

IBM, rejoint par plus de 100 partenaires commerciaux, lance le réseau IBM Digital Marketing dans le cloud et aide les directeurs marketing (CMO) et leurs équipes à intégrer plus rapidement et plus facilement de nouveaux services marketing, afin de mesurer et d’améliorer leur efficacité en temps réel.

Tasmania’s St Virgil’s College has signed a two-year agreement with IBM to equip staff and students with Apple iPads and Mobile Device Management (MDM) software as part of its digital education delivery commitment.

Customer transaction and processing time reduced with the new digital engagement

IBM (NYSE: IBM) today announced its intention to acquire Vivant Digital business (Vivant), a boutique digital and innovation agency based here. This acquisition extends the strategy and design expertise of IBM iX, one of the world’s largest digital agencies and global business design partners, with Vivant talent and expertise to accelerate clients’ digital transformations.

IBM (NYSE: IBM) today announced a new collaboration with Thiess, one of the world’s largest contract miners, to use Big Data to improve machine availability and operational productivity utilizing predictive analytics and modeling technologies. This initial collaboration focuses on Thiess’ Mining haul trucks and excavators, and will help unify asset management and business operations.

IBM (NYSE: IBM) today announced that Digital Alchemy, a leading Australian database marketing service provider, has extended its commitment to IBM’s Enterprise Marketing Management (EMM) software to more quickly and easily enable cross-channel interactive campaigns for its clients.

Все знают, коллектив MusicAeterna и его художественный руководитель Теодор Курентзис с декабря 2019 года активно работают над проектом культурно-образовательного центра Р. А. Д. И. О. в Санкт-Петербургском Доме Радио. Но карантин вносит в эту работу свои коррективы, и в конце апреля было объявлено об открытии digital platform — виртуальной творческой резиденции MusicAeterna. В скором времени на ней будет доступна онлайн-версия перформанса Алексея Ретинского «Слышать», посвященный Людвигу ван Бетховену. Анонсируем это событие статьей Анны Самсоненко, побывавшей на единственном представлении в феврале.

1. Covid-19 Delhi latest figures- 224 new cases take capital’s total to 8,630, India tally at 59,662  Hindustan Times
2. Confusion over Delhi's Covid-19 toll as govt data, figures from hospitals don't match  Times of India
3. 3 More Private Hospitals To Treat COVID-19 Patients In Delhi  NDTV
4. Delhi Covid-19 tally tops 6,000 with 338 new cases in last 24 hours  Livemint
5. 100 rooms in Delhi's five-star hotels now hospitals  Times of India
6. View Full coverage on Google News

Seven Sketches in Compositionality: An Invitation to Applied Category Theory

2018 by Brendan Fong and David I. Spivak

Category theory is becoming a central hub for all of pure mathematics. It is unmatched in its ability to organize and layer abstractions, to find commonalities between structures of all sorts, and to facilitate communication between different mathematical communities. But it has also been branching out into science, informatics, and industry. We believe that it has the potential to be a major cohesive force in the world, building rigorous bridges between disparate worlds, both theoretical and practical. The motto at MIT is mens et manus, Latin for mind and hand. We believe that category theory—and pure math in general—has stayed in the realm of mind for too long; it is ripe to be brought to hand.