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Traffic Safety News – Cell Phone in One Hand, Ticket in the Other

Distracted Driving. Many of us are guilty of it. Did you know that drivers who use hand-held devices are 4 times more likely to get into crashes serious enough to injure themselves? But there is more to Distracted Driving than just talking on a cell phone and texting.




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Traffic Safety News – Cell Phone in One Hand, Ticket in the Other.

For some, using a cell phone, smart phone, or other electronic device is part of daily life. We depend on this technology for a variety of reasons that make it difficult to put the phone down. But did you know that in 2012, 13,000 citations were issued statewide to people using a hand-held cell phone? Read more for the risks involved with being distracted while you are behind the wheel.




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Traffic Safety News – Cell Phone in One Hand, Ticket in the Other

Did you know that motorists who use hand-held devices while driving are 4 times more likely to get into crashes serious enough to injure themselves? It has become a common occurrence to see others talking on their hand-held cell phone or checking their smartphone while driving. You may even do it yourself. But there is more to Distracted Driving than just talking on a cell phone and texting.




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The cells that stoke the imaginations of Stanford Medicine scientists

Our researchers picked cells from all over the human body — cells of all shapes, sizes and abilities. From the brain to the heart to the intestines.

The post The cells that stoke the imaginations of Stanford Medicine scientists appeared first on Scope.




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Non-fullerene organic solar cells show speedy charge separation

Mapping the charge transport in new absorber material combinations points scientists on a different path towards efficient carbon-based solar cells.




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Gary Harris excelled at the ‘little things’ for Magic

Gary Harris’ impact on the Orlando Magic could be easy to overlook but he brought multiple "little things" to the team on and off the floor.




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Gary Harris excelled at the ‘little things’ for Magic

Gary Harris’ impact on the Orlando Magic could be easy to overlook but he brought multiple "little things" to the team on and off the floor.




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[ K.114 (08/22) ] - Electromagnetic compatibility requirements and measurement methods for digital cellular mobile communication base station equipment

Electromagnetic compatibility requirements and measurement methods for digital cellular mobile communication base station equipment




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[ E.807 (02/14) ] - Definitions, associated measurement methods and guidance targets of user-centric parameters for call handling in cellular mobile voice service

Definitions, associated measurement methods and guidance targets of user-centric parameters for call handling in cellular mobile voice service




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GSTP-CSS - The composite source signal as a measuring signal and a summary of various investigations on speech echo cancellers

GSTP-CSS - The composite source signal as a measuring signal and a summary of various investigations on speech echo cancellers




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[ G.993.5 (02/19) ] - Self-FEXT cancellation (vectoring) for use with VDSL2 transceivers

Self-FEXT cancellation (vectoring) for use with VDSL2 transceivers




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[ V.152 (2005) Amendment 1 (03/09) ] - New Annex B - Use of data signal detection and silence insertion in voiceband data, and new Annex C on use of V.21 preamble for echo canceller control in a V.152 gateway

New Annex B - Use of data signal detection and silence insertion in voiceband data, and new Annex C on use of V.21 preamble for echo canceller control in a V.152 gateway







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MRCA Seeks Nominees for Naphis Mitchell Reyes Excellence in Safety Award

Help honor a safety professional in the roofing industry by nominating them for the MRCA's 2024 Naphis Mitchell Reyes Excellence in Safety Award.




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Joan Balcells, la vida sin patillas del héroe de la primera Davis española: "Me rapé obligado, los años pasan"

El ex jugador, ahora entrenador en Badalona, repasa su carrera, de su victoria ante Federer a sus años de fama con un look marcado Leer




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FDA discourages use of laparoscopic power morcellation for hysterectomies

Dr. Jessica Shepherd, Assistant Professor of Clinical Obstetrics and Gynecology at the University of Illinois College of Medicine explains why the FDA discourages use of a laparoscopic surgery for hysterectomies and removal of uterine fibroids.




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Dakota and Truckfile named as Finalists in the ‘Fleet Innovation of the Year’ category at the Supply Chain Excellence Awards 2023

Real-time data capture, printing, mobility and voice-directed solutions specialist Dakota, alongside partners Truckfile, the UK provider of web-based fleet and workshop management, drivers check and compliance systems, have been selected as finalists in the ‘Fleet Innovation of the Year’ Category at the Supply Chain Excellence Awards 2023.




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Make UK comments on speech by the Chancellor

Commenting on the speech by the Chancellor of the Exchequer, Stephen Phipson, Chief Executive of Make UK, said: “Industry will welcome the Chancellor’s commitment to a vision for the economy which has a long-term industrial strategy at its heart.





cell

Körber drives the efficiency of cell and gene therapy manufacturing and logistics

The international technology group Körber is driving the integration of supply chain and data orchestration platforms into its Werum PAS-X Manufacturing Execution System (MES).




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Automotive and aerospace quality excellence being transferred to other manufacturing sectors

Manufacturers in the rail, marine, defence and household good sectors can now benefit from more than 25 years of automotive and aerospace quality excellence as G&P is undergoing a proactive diversification drive across adjacent sectors.




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New awards to celebrate marketing excellence in manufacturing

A new awards event has been launched to reward excellence in marketing the application of STEM skills in the manufacturing sector. The STEM Marketing Awards will champion the work of organisations operating in STEM-related industries across the UK, with companies working in relevant sectors now invited to enter. 




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Rhenus Warehousing Solutions UK wins the UKWA Award for Excellence in Infrastructure

Rhenus Warehousing Solutions UK was crowned the winner in the Infrastructure category at the UKWA Annual Lunch & Awards in London.




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Federal Executive Forum Chief Data Officers Profiles in Excellence in Government 2024: Data Analytics & Artificial Intelligence Trends

What strategies and technology are driving data strategy in government?

The post Federal Executive Forum Chief Data Officers Profiles in Excellence in Government 2024: Data Analytics & Artificial Intelligence Trends first appeared on Federal News Network.




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While Not as Cute as Dogs, Giant Rats Are Excellent at Sniffing Out Illicit Goods

Rodents could be used to find illicit goods at airports and harbors in places where dogs can’t easily access.




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Mitochondria and Cell Death

Location: Electronic Resource- 




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Regenerative Medicine - from Protocol to Patient 2. Stem Cell Science and Technology

Location: Electronic Resource- 




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Autophagy at the Cell, Tissue and Organismal Level

Location: Electronic Resource- 




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Cell Reprogramming Methods and Protocols

Location: Electronic Resource- 




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Embryonic Stem Cell Protocols

Location: Electronic Resource- 




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Patient-Specific Induced Pluripotent Stem Cell Models Generation and Characterization

Location: Electronic Resource- 




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Induced Pluripotent Stem (iPS) Cells Methods and Protocols

Location: Electronic Resource- 




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Programmed Cell Death Methods and Protocols

Location: Electronic Resource- 




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Hydrocarbon and Lipid Microbiology Protocols Single-Cell and Single-Molecule Methods

Location: Electronic Resource- 




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Design and deployment of small cell networks

Location: Engineering Library- TK5103.2.D47 2016




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Navigating the ins and Outs of Ryanair Cancellation Policy

Navigating The Ins And Outs Of Ryanair Cancellation Policy

John Alex...




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CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients

CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients

In the first-ever (sanctioned) investigational use of multiple edits to the human genome, a study found that cells edited in three specific ways and then removed from patients and brought back into the lab setting were able to kill cancer months after their original manufacturing and infusion.

This is the first U.S. clinical trial to test the gene editing approach in humans, and the publication of this new data today follows on the initial report last year that researchers were able to use CRISPR/Cas9 technology to successfully edit three cancer patients' immune cells. The ongoing study is a cooperative between Tmunity Therapeutics, the Parker Institute for Cancer Immunotherapy, and the University of Pennsylvania. 

Patients on this trial were treated by Edward A. Stadtmauer, MD, section chief of Hematologic Malignancies at Penn, co-lead author on the study. The approach in this study is closely related to CAR T cell therapy, in which patient immune cells are engineered to fight cancer, but it has some key differences. Just like CAR T, researchers in this study began by collecting a patient's T cells from blood. However, instead of arming these cells with a receptor against a protein such as CD19, the team first used CRISPR/Cas9 editing to remove three genes. The first two edits removed a T cell's natural receptors so they can be reprogrammed to express a synthetic T cell receptor, allowing these cells to seek out and destroy tumors. The third edit removed PD-1, a natural checkpoint that sometimes blocks T cells from doing their job. 

Once the three genes are knocked out, a fourth genetic modification was accomplished using a lentivirus to insert the cancer-specific synthetic T cell receptor, which tells the edited T cells to target an antigen called NY-ESO-1. Previously published data show these cells typically survive for less than a week, but this new analysis shows the edited cells used in this study persisted, with the longest follow up at nine months. 

Several months after the infusion, researchers drew more blood and isolated the CRISPR-edited cells for study. When brought back into the lab setting, the cells were still able to kill tumors. 

The CRISPR-edited T cells used in this study are not active on their own like CAR T cells. Instead, they require the cooperation of a molecule known as HLA-A*02:01, which is only expressed in a subset of patients. This means that patients had to be screened ahead of time to make sure they were a match for the approach. Participants who met the requirements received other clinically-indicated therapy as needed while they waited for their cells to be manufactured. Once that process was completed, all three patients received the gene-edited cells in a single infusion after a short course of chemotherapy. Analysis of blood samples revealed that all three participants had the CRISPR-edited T cells take root and thrive in the patients. While none responded to the therapy, there were no treatment-related serious adverse events. 

CRISPR technology has not previously been tested in humans in the U.S. so the research team had to move through a comprehensive and rigorous series of institutional and federal regulatory approval steps, including approval by the National Institutes of Health's Recombinant DNA Research Advisory Committee and review by the U.S. Food and Drug Administration, as well as Penn's institutional review board and institutional biosafety committee. The entire process required more than two years.

 Researchers say these new data will open the door to later stage studies to investigate and extend this approach to a broader field beyond cancer, several of which are already planned at Penn.

sb admin Thu, 02/06/2020 - 14:52
Categories




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L.A. Times, Washington Post see subscription cancellations over not endorsing in presidential race

The Washington Post has lost about 8% of its readers and the L.A. Times 1.8%. But some argue to stay with the newspapers for their roles in reality checking Donald Trump.




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Newly Found Fat Cell Uses a Different Approach to Heat the Body  

Single-cell sequencing unpacked 10 varieties of fat cells, including one that uses an alternative heat-regulating strategy that protects against weight gain.



  • News & Opinion
  • News

cell

Introducing iQue®'s 2nd Edition High-Throughput Cytometry Handbook: Fast. Simple. Discover the Future of Cell Analysis!

This handbook is designed to empower both new and seasoned flow cytometry users who are curious about the unique capabilities of HTS cytometry.




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Transforming 3D biology using AI: Tomocube’s HT-X1™ Plus accelerates cellular and organoids label-free analysis

This new system raises the bar in high-resolution, high-throughput 3D imaging for cells and organoids, providing researchers with faster, more detailed, and more accurate insights into biological processes.




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Optimizing Stem Cell Media for Cultivated Meat Production

In this webinar, Alex Rimmer, Samuel East, and Catriona Jamieson will discuss how they developed low-cost, animal-free culture media for cellular agriculture.




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Live Imaging Intracellular Parasites Reveals Changes to Host Metabolism

Researchers found that Toxoplasma gondii increased the host cell’s metabolic activity, offering insights into potential treatment strategies. 



  • News
  • News & Opinion

cell

A Fungal Messenger Impairs Immune Cell Function

Farnesol, a fungal signaling molecule, alters lipid synthesis in dendritic cells, causing mitochondrial dysfunction and decreased inflammatory responding.



  • News
  • News & Opinion

cell

How Stem Cells Stay Young

Bone marrow stem cells defy typical aging, and it may be because they express the right proteins.



  • News
  • News & Opinion

cell

New collection: Anti-Cellulite Mid-thigh Firm Control

A new collection of pantyhose
by Hanes. Visibly reduces the appearance of cellulite.





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Christmas is cancelled

Andy Munro issues a pre-festive plea.