A bunch of asteroids near Jupiter and Neptune with orbits perpendicular to the plane of the solar system may have come here from a different star system

Yesenia Perez-Cruz started her career as a designer at Happy Cog Philadelphia. From the first day, her design gifts were unmistakable. As her career progressed, she moved from one challenging role to another. At companies like Vox Media and Shopify, and at conferences around the world, she has been a design team leader, a popular […]

The post Expressive Design Systems appeared first on Zeldman on Web & Interaction Design.

The routing ecosystem around React and React Native is quite different. One is characterized by a strong incumbent, and the other is plagued by rapid change.

React JS

No question about it, React Router (ReactTraining/react-router) is king here. They have the benefit of several years of active development, along with an active community submitting PR’s, fixes, etc. Supplement that with myriad tutorials and how-to’s and you end up with a well-supported, stable product. To be fair, React Router has suffered some major API upsets, and is nearly the poster-child for javascript fatigue but the maintainers have declared their lasting support for a few specific versions, which means you can plop down with V3 and be good to go for the next 12 to 24 months.

React Native

Ok, this is where things start to get really, really crazy. The most important thing to keep in mind is that the React Native team has produced three navigation helpers: NavigatorIOS, Navigator, and NavigatorExperimental.

• NavigatorIOS was quickly deprecated, as it was supported only by (you guessed it) IOS.
• Navigator is the currently endorsed solution for navigation, at least if you are following the official docs. However, its about to be upset by-
• NavigationExperimental. This is an updated navigator that has learned some lessons from Navigator, and has some solid integration with Redux. ‘Navigator’ is (or was!) sleighted to be deprecated in favor of NavigationExperimental at some point.

Already you have three ‘official’ navigators supported by the React Native team. The big issue with all three of these is that they are somewhat lightweight and don’t include a lot of common navigation situations out of the box, like sidebars, tab bars, headers, etc. To solve that, the community has introduced…

• React Native Router Flux (aksonov/react-native-router-flux). My personal favorite, this is router is based upon NavigationExperimental. You can imagine that the authors looked at NavigationExperimental, realized that everyone would be writing the same wrapper code around it, and so created this project.
• React Native Router (t4t5/react-native-router). Haven’t used it, but it is colossally popular.
• React Router Native (jmurzy/react-router-native). Strives for API conformity with React Router (the above mentioned one). The great approach here is that they bring in the concept of a URL in native apps, where one doesn’t otherwise exist. This is a great approach that simplifies a lot of common routing situations. Of course, there’s one more big solution that is supposedly going to become the standard:
• React Navigation (react-community/react-navigation). Seen as a solution that will soon be ‘official’ in the community, it is intended to replaced NavigationExperimental. This package is still in active development, so I expect at least a bit of API upset over the coming months. If you want to use official solutions, go with this, if you want a tried and true solution, go with React Native Router Flux.

Representational Image

Components in the mosquito saliva can trigger an unexpected and long-lasting immune responses -- up to seven days post-bite, say scientists.

The researchers found that more than 100 proteins in mosquito saliva are mediating the effects on the immune system, or may help the virus become more infectious.

Identifying these proteins could help design strategies to fight transmission of dengue fever as well as other diseases caused by viruses also transmitted by Aedes aegypti, such as Zika virus, chikungunya virus and yellow fever virus, the researchers said.

"We found that mosquito-delivered saliva induced a varied and complex immune response we were not anticipating," said Silke Paust, Assistant Professor at Baylor and Texas Children's Hospital.

"Billions of people worldwide are exposed to diseases transmitted by mosquitoes, and many of these conditions do not have effective treatments," added Rebecca Rico-Hesse, Professor at the Baylor College of Medicine in Texas, US.

For the study, appearing in the journal PLOS Neglected Tropical Diseases, the team worked with a mouse model of the human immune system.

Previously, the team demonstrated that mosquito-bite delivery and needle-injection delivery of dengue virus in these "humanised mice" led to significantly different disease developments

They found that mosquitoes are not just acting like "syringes" to merely inject viruses, but their saliva seems to contribute significantly to the development of the disease.

In the new study, the team tested the effect of virus-free mosquito saliva on humanised mice and compared the results with those obtained from humanised mice that had not been bitten by mosquitoes.

Evidence to immune responses -- up to seven days post-bite -- was found in multiple tissue types, including blood, skin and bone marrow, the researchers said.

"For instance, both the immune cell responses and the cytokine levels were affected. We saw activation of T helper cells 1, which generally contribute to antiviral immunity, as well as activation of T helper cells 2, which have been linked to allergic responses," Paust said.

"The diversity of the immune response was most striking to me. This is surprising given that no actual infection with any type of infectious agent occurred," he noted.

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates

A fire broke out in an apartment on the sixth floor of the Atlas building on Napean Sea Road on Tuesday morning. While the occupants managed to rush down to safety, two women on the upper floors got stuck and were rescued by the fire brigade personnel.

The Mumbai Fire Brigade said the fire was reported at 4.41 am and they reached the site at 4.55 am with three fire engines, four jumbo tankers and one turntable ladder. However, they faced hurdles as the road leading to the building was packed because of parking.

"The team reached on time, but there several vehicles were parked on the road, blocking fire fighting vehicles' way to the building," said local corporator Jyotsna Mehta.

The firemen then went to the opposite building and were able to douse the flames after almost four hours. Deputy Fire Officer A J Mishra also pointed out that the parking was one of the major hurdle in the operation. "There was a strong wind too," he said. "We got a water connection and started operation from the opposite building to stop the vertical spread of the fire. So the major casualty averted," he said, adding that the fire was brought under control around 8.40 am.

A fireman said, "The residents left all the doors of the flat open. So it was difficult to search the origin of the fire. Besides, there wasn't a fire fighting system inside the building that is more than 30 years old."

The cause of the fire is not known.

Catch up on all the latest Mumbai news, crime news, current affairs, and a complete guide from food to things to do and events across Mumbai. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

Token system has been introduced for the purchase of alcohol from liquor stores in Pune, said Divisional Commissioner Deepak Mhaisekar on Tuesday. He said there will be an implementation of a token system at these stores and without a token, no liquor can be purchased.

On Tuesday, Pune Police registered cases against nine liquor stores for not following the COVID-19 health guidelines.

The move comes as liquor stores witnessed huge rush across the country after the relaxation of lockdown norms by several state governments over the past few days.

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

The Minerals Council of Australia has published a report it says confirms that the country's high company tax rate is damaging mining firms' ability to compete internationally for capital investment.

Meeting on May 4, 2018, India's GST Council approved plans to simplify GST filing obligations.

The European Commission and the Swiss Federal Council have each approved proposals to link their emissions trading systems, meaning formal signature of a new agreement could take place by the end of the year.

The Swiss Federal Council is consulting on proposed changes to the CO2 Ordinance, which would link the Swiss and EU emissions trading systems.

Switzerland and the EU are to link their emissions trading systems from next year, after the Swiss Federal Council approved revisions to the country's Ordinance on the Reduction of CO2 Emissions.

The South African Revenue Service announced on October 30 that it had paid over ZAR120bn (USD8.4bn) in refunds across all tax types in the last seven months, from the beginning of April of the tax season to date.

The Consumers Association of Penang (CAP) has called on the Malaysian Government to reintroduce inheritance tax in the Budget 2018.

Highights: Mussels help in treating myocardial infarction (MI) A protein from mussels and stem cells help t

The European Commission has released a paper recommending improvements to France's "inefficient" value-added tax system, including that the country do away with broadly applying reduced VAT rates.

Switzerland and the EU are to link their emissions trading systems from next year, after the Swiss Federal Council approved revisions to the country's Ordinance on the Reduction of CO2 Emissions.

The advisory board tasked with reporting on the state of Switzerland's financial center has recommended that the country overhaul its withholding tax system to improve its capital market offering.

The Dutch Government has launched a consultation exercise on plans to review the country's tax treaty policy and to draw up a list of low-tax jurisdictions for the purposes of enforcing incoming controlled foreign company rules.

In a new study with mice, high-salt diet was associated with bacterial infections. In human volunteers who consumed an additional six grams of salt per day also showed pronounced immune deficiencies.

Supplementation of micronutrients and omega-3 fatty acids is a safe, effective, and low-cost strategy for an optimal immune function to fight against

Dental stem cells extracted from baby teeth can help in the regeneration of dental tissues, reports a new study. The findings of the study are published

17th January 2014 – Colombo, Sri Lanka – His Excellency Mahinda Rajapaksa, President of the Democratic Socialist Republic of Sri Lanka, has officially launched a new, hi-tech information system that promises to enhance water management in the South Asian country. Download the full media release

2nd February 2014 – Colombo, Sri Lanka Agriculture and wetlands should be managed in unison in order to conserve vital ecosystems and support the livelihoods of millions of people, according to a new report published to coincide with World Wetlands Day, today. Download the full media release Download the report

Experts meet in Delhi to discuss how South Asian countries could adopt the new drought monitoring system to better prepare and mitigate drought risks

Research conducted in Bangladesh could have dramatic implications both for poor households and the entire wastewater value chain.

The International Rice Research Institute (IRRI) South Asia Office in India, convened a multi-sectoral panel discussion on - “Creating Sustainable Value Chains for Transforming Food Systems” on 4 Feb 2020, at the National Agricultural Science Complex in Delhi.

The Pyawt Ywar pump irrigation scheme, on which the project focused, was established in 2004 by Myanmar’s Irrigation and Water Utilisation Management Department. Designed to increase agricultural production and achieve food

"In the water sector we always say 'Don't waste a good crisis'," said Inga Jacobs-Mata, the South African representative from non-profit research group the International Water Management Institute (IWMI).

“In the water sector we always say 'Don't waste a good crisis'," said Inga Jacobs-Mata, the South African representative from non-profit research group the International Water Management Institute (IWMI).

IRRI, WorldFish and IWMI have signed a 5-year agreement that provides the framework for cooperative research.

New study developed a novel way to make blood stem cells present in the umbilical cord 'more transplantable' that could improve the treatment of a wide range of blood diseases in kids and adults.

New unique immunotherapy delivery system kills cold tumors by binding to the tumors' collagen, using interleukin 12 (IL-12) protein to inflame the tumor.

On International Women’s Day, Deepa Joshi shares a lesson from South Africa to demonstrate why delivering gender equality demands far-reaching systems change.

"In the water sector we always say 'Don't waste a good crisis'," said Inga Jacobs-Mata, the South African representative from non-profit research group the International Water Management Institute (IWMI).

“In the water sector we always say 'Don't waste a good crisis'," said Inga Jacobs-Mata, the South African representative from non-profit research group the International Water Management Institute (IWMI).

Pluripotent stem cells research provides insight into how Huntington's Disease (HD) develops and may help pave the way for identifying pathways for future treatments.

Stem cell therapy aids a 26-year-old Duchenne Muscular Dystrophy (DMD) patient in UP to survive. Children suffering from DMD usually die of cardio-respiratory failure.

Healthy donor stem cells that produce normal collagen in Osteogenesis imperfecta (OI) patients have the potential to improve bone mass and correct the mutant collagen matrix, reports a new study.

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) were found to display unlimited proliferative potential in culture, which

There is no link between oral infections and the risk of stem cell transplantation patients dying of or getting a serious infection within six months of the procedure, found new study.

Researchers discovered a polymer sheet that functions as an artificial muscle as it transforms stem cells into bones. Stem cells are known for their

Human stem cells can provide long lasting pain relief without producing any side effects, in a single treatment, according to a study done on mice. The

A new study in mice has revealed administering stem cell or enzyme therapy in utero paves path to alleviating some congenital diseases that often result in losing a pregnancy.

Specific nutrients were found to directly influence the stem cell development, revealed Biomedical scientists from KU Leuven and Harvard University published these results in Nature.

A novel approach to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation has been discovered by Mount Sinai researchers.

Youthful strength can be regained after the existing muscle stem cells are subjected to the rejuvenating protein treatment, and transplanted back into our bodies, reports a new study.

Blood-forming stem cells' stiffness was found to facilitate mobilization procedures used for stem cell-based transplants, said Winship Cancer Institute

Introduction of a soft opt (and) #8208;out system of consent significantly boosted organ donation consent though the impact was not immediate, reports a new study.

Nursing has evolved into a modern medical profession and nurses have become an indispensable part of the country's health care system, says President Pranab Mukherjee.

Stem cells are able to postpone their own death in order to respond to an injury that needs their attention. "Planarian stem cells, even when challenged