These flying reptiles patrolled the African skies some 100 million years ago

The children's book author and illustrator purchased the repurposed World War II vessel in 1967

The Archaeological Institute of America launched its Build Your Own Monument challenge early to inspire families quarantining at home

Currently in the works, the new monument will honor her contributions and legacy with a contemplative space

In 1847, the Choctaw Nation sent $170—more than $5,000 today—to victims of the Irish potato famine

A century ago, Susan Pringle Frost tirelessly campaigned to save these South Carolina buildings from destruction

A museum director looks to the past to explain why 'Aloha' is as necessary as ever

In a new twist on oral history, University of Alberta paleontologists have discovered that an Argentinian reptile from 95 million years ago developed a type of tooth enamel that is common in humans and other mammals but rare among reptiles.

The Best Museum Experience of All Things Washington, D.C. Experience the stories behind the people and events of the Nation's Capital.

OM’s team in Bar, Montenegro, has been praying to expand the outreach work in the country. Their prayers have finally been answered.

The world’s largest floating book fair welcomes its five millionth visitor as the tour of Asia comes to a conclusion.

Global carbon emissions from energy are expected to fall by almost 8% in 2020 in the biggest drop in history as a result of the pandemic, experts said.

“Scotland”, declared a young Alex Salmond in May 1975, “knows from bitter experience what treatment is in store for a powerless region of a common market.”

Infantile hypertrophic pyloric stenosis incidence varies over different regions and time periods. Recently, a decline was reported in the United States, Sweden (concurrent with a decline in sudden infant death syndrome), Scotland, and Denmark. The etiology remains unclear; therefore, epidemiologic data are valuable.

A decline in the incidence of infantile hypertrophic pyloric stenosis in Germany from 2000 to 2008 was noted but with wide regional variations. The regional distribution of infantile hypertrophic pyloric stenosis was different from that of sudden infant death syndrome. (Read the full article)

Pyloric stenosis is the most common condition requiring surgery in infants. It is typically not present at birth but develops within the first weeks after birth. The etiology is largely unknown, but bottle-feeding has been suggested as a risk factor.

This study demonstrated that bottle-fed infants had a 4.6-fold increased risk of developing pyloric stenosis compared with infants who were not bottle-fed. The result adds to the evidence supporting the advantage of exclusive breastfeeding in the first months after birth. (Read the full article)

Exposure to oral erythromycin in the first few weeks of life has been associated with the development of pyloric stenosis. Although azithromycin has become an acceptable alternative, little is known on whether this medication increases the risk of pyloric stenosis.

Exposure to oral azithromycin in the newborn period increases the risk of developing pyloric stenosis. Although this risk is highest if the exposure occurred in the first 2 weeks of life, the risk extends out to 6 weeks of age. (Read the full article)

Background. CLSI and EUCAST susceptibility breakpoints for voriconazole and C. albicans differ by one dilution (≤0.125 and ≤0.06 mg/l, respectively) whereas the epidemiological cutoff values (ECOFF/ECV) with both methodologies are the same (0.03 mg/L). We therefore determined the pharmacokinetic-pharmacodynamic (PK/PD) breakpoints of voriconazole against C. albicans for both methodologies with an in vitro PK/PD model, which was validated using existing animal PK/PD data.

Methods. Four clinical wild-type and non-wild-type C. albicans isolates (voriconazole MICs 0.008-0.125 mg/l) were tested in an in vitro PK/PD model. For validation purposes, mouse PK were simulated and in vitro PD were compared with in vivo outcome. Human PK were simulated and the exposure-effect relationship fAUC_0-24/MIC was described for EUCAST and CLSI24/48h methods. PK/PD breakpoints were determined using the fAUC_0-24/MIC associated with half-maximal activity (EI₅₀) and Monte Carlo simulation analysis.

Results. The in vitro 24h-PD EI₅₀ of voriconazole against C. albicans were 2.5-5 (1.5-17) fAUC/MIC. However, the 72h-PD were higher, 133 (51-347) fAUC/MIC for EUCAST and 94 (35-252) fAUC/MIC for CLSI. The mean (95% confidence interval) probability of target attainment (PTA) was 100(95-100)%, 97(72-100)%, 83(35-99)%, and 49(8-91)% and 100(97-100)%, 99(85-100)%, 91(52-100)% and 68(17-96)% for EUCAST and CLSI MICs 0.03, 0.06, 0.125, and 0.25 mg/L, respectively. Significantly, >95% PTAs were found for EUCAST/CLSI MICs ≤0.03 mg/ll. For MICs 0.06-0.125 mg/l trough levels 1-4 mg/ll would be required.

Conclusion. A PK/PD breakpoint of C. albicans voriconazole at the ECOFF/ECV of 0.03 mg/L was determined for both EUCAST/CLSI methods, indicating the need for breakpoint harmonization for the reference methodologies.

Penn State Abington faculty are using the current situation as an opportunity to enrich students academically and support them personally during this period of remote learning. "What may be most inspiring of all is the deep-seated concern for our students that faculty efforts expose,” said Friederike Baer, division head for Arts and Humanities.

Halloween programs, 18th century trades and William Penn Day among the events to be presented.

18th Century Market Fair, candle making and music of World War I among the events to be presented.

WILMINGTON, Del. – On Wednesday, November 1, Governor John Carney will host roundtable discussions with leaders in Delaware’s arts & culture, and historic preservation communities. The discussions are part of Governor Carney’s efforts to showcase Delaware as an attractive home for businesses and their employees. Follow Governor Carney’s discussions using the hashtag #OptionsInDE, and learn […]

Eight holiday-themed activities among the programs to be offered.

Museums closed Christmas Eve, Christmas Day, New Year’s Eve and New Year’s Day.

Highlights include activities celebrating Martin Luther King, Jr. Day, and programs on E.R. Johnson’s yacht the Caroline and buccaneers in the Delaware Bay.

Accreditation is the highest recognition afforded to museums in the United States.

Highlights include Buena Vista’s First Annual Spring Open House, The Old State House's Coffee-Hour Lecture Series and programs on Delaware's Dutch heritage.

Improvements slated to begin in the spring of 2018.

Highlights include Dover Days programs, A Day in Old New Castle and “A Sailor’s Life for Me,” the Zwaanendael Museum’s 7th Annual Maritime Celebration.

Programs on Delaware heroes of the War of 1812, dyeing fabrics 18th-century style, and Separation Day in New Castle to be featured.

Carlton Hall, a cultural preservation specialist and historian with the Delaware State Historic Preservation Office (SHPO), earned a place on the inaugural “40 Under 40” list recently unveiled by the National Trust for Historic Preservation.

Partner site of the First State National Historical Park to host summer 2018 events

Programs on quill-pen writing, Alexander Hamilton and a murder mystery to be featured.

Accreditation is the highest recognition afforded to museums in the United States.

Film screenings, and programs on Sherlock Holmes, and George M. Cohan and Irving Berlin to be featured.

Native-American programming, Chautauqua shows and surviving the London Blitz among activities to be presented.

Working to preserve Delaware’s heritage for the future, the plan outlines six broad goals for the next five years.

Early 1900s music education, the life of Delaware patriot Caesar Rodney and walking tours of St. Peter’s cemetery in Lewes among topics to be explored.

The event will include scholarly presentations on My Lord’s Gift, a 17th century archaeological site in Queenstown, Md.; and the Coleman Farm, Reedy Island and Fort Casimir sites in Delaware.

Changes to American society in the early 20th century, grave sites of notable New Castle veterans, and candle-making among topics to be explored.

Ten holiday-themed activities among the programs to be offered.

Highlights include activities celebrating Martin Luther King, Jr. Day, early jazz and the Avery’s Rest archaeological site.

Highlights include programs on the artist who created "His Master's Voice," the bombardment of Lewes and a festival at Fort Christina.

Dover Days, A Day in Old New Castle and the Zwaanendael Maritime Festival among programs to be offered.

Separation Day, Black Music Month Celebration and a historic preservation symposium among programs to be offered.

Sessions will explore disaster preparedness, issues regarding elevating historic properties in flood-prone areas and National Register nominations.

Programs on Independence Day, baseball Hall-of-Famer William “Judy” Johnson and campfires at the John Dickinson Plantation to be featured.

Sherlock Holmes comes to Delaware, a screening of “How to Train Your Dragon—The Hidden World” and the history of women's suffrage in the First State to be featured.

Chautauqua tent shows, Native-American programming and a historical play on Caesar Rodney among the activities to be presented.

Historical play about the Delaware patriot by museum historic-site interpreter David Price.

Programs on America's maritime heritage; Enrico Caruso; and Shakespeare, Poe and Fiends to be featured.