Honda and Alpine are fined by governing body the FIA after being found guilty of breaching Formula 1's cost-cap rules for engine manufacturers in 2023.

The Renault-owned Alpine team will use Mercedes engines in Formula 1 from the 2026 season.

The University of KwaZulu-Natal will share R2 million in research funding from the UK government to improve 3D-printing techniques for rocket engine components.

Platform engineering is the latest buzzword in IT operations. And like all other buzzwords, it’s in danger of becoming meaningless—in danger of meaning whatever some company with a “platform engineering” product wants to sell. We’ve seen that happen to too many useful concepts: Edge computing meant everything from caches at a cloud provider’s data center […]

Ignat V. Shilov
Sep 1, 2007; 6:1638-1655
Technology

DNA polymerases are today used throughout scientific research, biotechnology, and medicine, in part for their ability to interact with unnatural forms of DNA created by synthetic biologists. Here especially, natural DNA polymerases often do not have the “performance specifications” needed for transformative technologies. This creates a need for science-guided rational (or semi-rational) engineering to identify variants that replicate unnatural base pairs (UBPs), unnatural backbones, tags, or other evolutionarily novel features of unnatural DNA. In this review, we provide a brief overview of the chemistry and properties of replicative DNA polymerases and their evolved variants, focusing on the Klenow fragment of Taq DNA polymerase (Klentaq). We describe comparative structural, enzymatic, and molecular dynamics studies of WT and Klentaq variants, complexed with natural or noncanonical substrates. Combining these methods provides insight into how specific amino acid substitutions distant from the active site in a Klentaq DNA polymerase variant (ZP Klentaq) contribute to its ability to replicate UBPs with improved efficiency compared with Klentaq. This approach can therefore serve to guide any future rational engineering of replicative DNA polymerases.

Decades of obsolete and unpatched hardware and software endanger us all

You might receive a Segmentation Violation when opening a database table in SAS. The SAS Log contains the error and traceback:

A Qantas airlines flight made an emergency landing at Sydney Airport on Friday afternoon after suffering engine failure shortly after takeoff, the company said.

This is a Remote Eligible open rank research software engineer position. The OIT (Office of Information Technology) department, Home | Office of Information Technology (oit.gatech.edu) at the Georgia Institute of Technology in Atlanta, Georgia invites applications for Partnership for Advanced Computing Environment (PACE) (pace.gatech.edu). This is a research faculty position, applications will be considered at all ranks. We seek a highly skilled and innovative Research Scientist to join our research software engineer team. The successful candidate will lead software lifecycle management with security and compliance efforts in PACE, in collaboration with other researchers, play a key role in supporting sensitive/regulated research projects while ensuring compliance with applicable regulations and security requirements. This position will also be responsible for the PACE software vulnerability management program. This role will closely work with the Research Facilitation and Cyberinfrastructure Teams to bring support to GT faculty on regulated research projects and evaluate underlying technologies. This role requires strong software engineering expertise, excellent communication skills, and the ability to bring innovative solutions to researchers’ projects and implement them to deliverable. Responsibilities • Define and implement standard operating procedures to incorporate software vulnerability management • Coordinate with other cyber security and research security personnel to satisfy software audit and compliance requirements • Software Bill of Materials (SBOM) management, identify and address software vulnerability for the PACE software stack • Take responsibility for the audit and compliance of restricted software/code (e.g. RSICC/NASA) • Provide domain expertise on CUI (Controlled Unclassified Information) and regulated software • Provide support on commercial/licensed software in the regulated environment • Work in partnership with other GT Colleges’ IT groups to support the deployment of HPC scientific applications and workflows for researchers on PACE systems • Closely work with other internal PACE units, including the Research Computing Facilitation (RCF) and Cyberinfrastructure (CI) teams, to address researchers’ needs • Coordinate review and software access processes with other research cyber security personnel • Implement best practices around research computing software vulnerability management • Research and evaluate any new technologies in software vulnerability and closely monitor NIST regulations • Author and publish scientific papers, reports, and presentations to communicate research results and findings to internal and external audiences

SANTA CLARA, Calif., Oct. 25, 2024 — ServiceNow has announced that enterprise software industry veteran Amit Zavery will join the company as president, chief product officer (CPO), and chief operating officer […]

The post Google Cloud and Oracle Veteran Amit Zavery to Spearhead Product and Engineering at ServiceNow appeared first on HPCwire.

Noritaka Hoshi, Senior Manager, AI Platform Division, talks about the impetus for and challenges within the development of SX-Aurora TSUBASA or a massive SIMD, created to handle enormous computing and […]

The post Advance Science, Technology and Sophistication with SX-Aurora TSUBASA or Vector Processor or Vector Engine (VE) appeared first on HPCwire.

Raghunandan Mathur, Senior Systems Engineer, NEC, discusses now with modern day programming frameworks designed around the paradigms of scalar architectures and vector-like extensions, many present-day programmers expect a major learning […]

The post Ease of programming on NEC’s Vector Engine or SX-Aurora TSUBASA appeared first on HPCwire.

How can manufacturers apply lessons learned from the dawn of the “Exascale Era” to Computer-Aided Engineering to achieve results like never before? Join Addison Snell, CEO, Intersect360 Research, Bill Mannel, VP, High Performance […]

The post Leveraging Exascale Era Technology for Advanced Computer-Aided Engineering appeared first on HPCwire.

Stimulating the sleeping brain may ease suffering from memory loss, stroke or mental health problems

NASA engineers fired the engines on the X-59 research aircraft in advance of planned test flights to determine if the aircraft can reduce sonic booms and make supersonic flight over land quieter.

Mary Jackson's story is among those depicted in the book "Hidden Figures," which focused on the lives of black women who worked as mathematicians and engineers for NASA during the Space Race. Before landing there, Jackson worked as a math teacher in Maryland.

Tessa E.S. Charlesworth
Sep 11, 2019; 39:7228-7243
Viewpoints

In a new book, a curator at England's Natural History Museum describes rare and interesting nests and eggs—from the house sparrow to the village weaver—and the lessons they hold for avian conservation

Human beings and chimps share as much as 98 percent of their DNA. If our species are so similar, can chimps be genetically engineered to be more like us?

Smithsonian Secretary Wayne Clough offers personal insights on the realities of climate change and the best ways for society to adapt

Control Engineering Recognizes SolidWorks® 2009 for Design Simulation

Free SolidWorks 3D CAD Software, Training, and Certification will Build Valuable New Skills Employers Need

Displaced Workers Get Free SolidWorks CAD Software,Learn It, and Obtain New Jobs

Intuitive 3D CAD Software, Used So Often by Professionals, Prepares EUSS Students for Success

‘Let’s Go Design’ TV Debuts Today

SolidWorks Education Edition 2010-2011 Equips Students for Sustainable Design Careers

Formula SAE and Formula Student teams increasingly demand SolidWorks software for its ease of use and integrated design analysis

U.K.

University

SolidWorks provides the industry's most comprehensive list of partner product solutions

#1 3D CAD software is first in industry to be highlighted in popular series renowned for clarity, humor, and gentleness

M G Bennett & Associates designs machine to help test U.K. 's oldest major suspension bridge

Software's assembly features and interoperability with 2D files

World's #1 mainstream analysis software adds 100-plus new features that put powerful design validation in easy-to-use packages

Students cut 20 percent out of initial project development time with SolidWorks 3D modeling and COSMOS design analysis software

COSMOS wins readers' nod in software and information integration category

First-ever combination helps engineers find the information they need to create better designs faster

Names SolidWorks Corporation's suite of COSMOS design analysis software one of the top innovations of 2004

Besser Company has significantly compressed its mold design cycle

Aarhus purchases 500 licenses of SolidWorks 3D CAD and COSMOS design analysis software to teach students engineering fundamentals

U.K. firm designs smaller scale, more affordable custom test rigs for companies like Rolls Royce to help meet new regulations

Monorail and plant automation company uses SolidWorks software to work faster and smarter, and detect collisions earlier

Students will begin learning 3D mechanical design as early as seventh grade

Top-placing teams cite software's short learning curve and focus on designing better products

SOLIDWORKS design and COSMOS analysis software and technical support bring engineering fun, 3D CAD understanding to contests

COSMOS enables engineers to catch and correct errors early in the design process, encouraging innovation and better product design