Title: Does Hope Have a Dark Side?
Category: Health News
Created: 8/26/2010 10:10:00 AM
Last Editorial Review: 8/27/2010 12:00:00 AM

Title: Adding Plavix to Aspirin Doesn't Help Guard Against Second Stroke: Study
Category: Health News
Created: 8/29/2012 6:05:00 PM
Last Editorial Review: 8/30/2012 12:00:00 AM

Title: One Part of the Brain Doesn't Age, Study Suggests
Category: Health News
Created: 8/22/2014 4:36:00 PM
Last Editorial Review: 8/25/2014 12:00:00 AM

Title: Polyp Removal Doesn't Always Signal Raised Colon Cancer Risk, Study Says
Category: Health News
Created: 8/27/2014 5:36:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM

Title: MERS Virus Doesn't Seem to Spread Easily, Study Finds
Category: Health News
Created: 8/27/2014 5:36:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM

Title: Does Your Child Need Eyeglasses?
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: 'Pretend Mommy' Program Doesn't Deter Teen Pregnancy
Category: Health News
Created: 8/25/2016 12:00:00 AM
Last Editorial Review: 8/26/2016 12:00:00 AM

Title: Does Race Matter in Care 'Preemie' Babies Receive?
Category: Health News
Created: 8/28/2017 12:00:00 AM
Last Editorial Review: 8/29/2017 12:00:00 AM

Title: Oxygen Therapy Doesn't Boost Heart Attack Survival
Category: Health News
Created: 8/30/2017 12:00:00 AM
Last Editorial Review: 8/31/2017 12:00:00 AM

Title: HPV Vaccine Doesn't Put Girls' Fertility at Risk: Study
Category: Health News
Created: 8/24/2018 12:00:00 AM
Last Editorial Review: 8/27/2018 12:00:00 AM

Title: Does Remdesivir Work Against COVID-19?
Category: Health News
Created: 8/21/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM

Title: Enlarged Prostate Doesn't Raise a Man's Odds for Cancer: Study
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM

Title: What Does a Neurologist Do for a Vestibular Migraine?
Category: Diseases and Conditions
Created: 6/22/2022 12:00:00 AM
Last Editorial Review: 6/22/2022 12:00:00 AM

Title: Does Hot Chocolate Have Caffeine? Hot Chocolate vs. Coffee & Tea
Category: Health and Living
Created: 8/26/2022 12:00:00 AM
Last Editorial Review: 8/26/2022 12:00:00 AM

Title: Does Coffee Raise Cholesterol?
Category: Health News
Created: 5/11/2022 12:00:00 AM
Last Editorial Review: 5/12/2022 12:00:00 AM

Title: Does Tinnitus Ever Go Away?
Category: Diseases and Conditions
Created: 6/3/2022 12:00:00 AM
Last Editorial Review: 6/3/2022 12:00:00 AM

Title: How Does a Man Deal With Menopause?
Category: Diseases and Conditions
Created: 4/27/2022 12:00:00 AM
Last Editorial Review: 4/27/2022 12:00:00 AM

Title: Does Menopause Make You More Sensitive to Pain?
Category: Diseases and Conditions
Created: 5/11/2022 12:00:00 AM
Last Editorial Review: 5/11/2022 12:00:00 AM

Title: pseudoephedrine
Category: Medications
Created: 8/9/2022 12:00:00 AM
Last Editorial Review: 8/9/2022 12:00:00 AM

Extract

In 2021, the World Health Organization (WHO) issued recommendations for the use of artificial intelligence (AI), affirming the technology could be used instead of human readers for the interpretation of chest radiograph (CXR) images for the screening and triage of tuberculosis (TB), marking a historic precedent for a guideline on AI in health [1]. The forward-looking guidance highlights the utility of CXR in TB, despite past reluctance from WHO to use it in TB programmes [2]. Employing CXR in a diagnostic algorithm can identify people with subclinical TB who are asymptomatic but have lung pathology suggestive of TB, and refer them for testing and diagnosis [3].

Pregnane X receptor (PXR) belongs to the nuclear receptor superfamily that plays a crucial role in hepatic physiologic and pathologic conditions. Phase separation is a process in which biomacromolecules aggregate and condense into a dense phase as liquid condensates and coexist with a dilute phase, contributing to various cellular and biologic functions. Until now, whether PXR could undergo phase separation remains unclear. This study aimed to investigate whether PXR undergoes phase separation. Analysis of the intrinsically disordered regions (IDRs) using algorithm tools indicated a low propensity of PXR to undergo phase separation. Experimental assays such as hyperosmotic stress, agonist treatment, and optoDroplets assay demonstrated the absence of phase separation for PXR. OptoDroplets assay revealed the inability of the fusion protein of Cry2 with PXR to form condensates upon blue light stimulation. Moreover, phase separation of PXR did not occur even though the mRNA and protein expression levels of PXR target, cytochrome P450 3A4, changed after sorbitol treatment. In conclusion, for the first time, these findings suggested that exogenous PXR does not undergo phase separation following activation or under hyperosmotic stress in nucleus of cells.

Surprisingly little attention has been given to the impact of selfing on speciation, even though selfing reduces gene flow between populations and affects other key population genetics parameters. Here we review recent theoretical work and compile empirical data from crossing experiments and genomic and phylogenetic studies to assess the effect of mating systems on the speciation process. In accordance with theoretical predictions, we find that accumulation of hybrid incompatibilities seems to be accelerated in selfers, but there is so far limited empirical support for a predicted bias toward underdominant loci. Phylogenetic evidence is scarce and contradictory, including studies suggesting that selfing either promotes or hampers speciation rate. Further studies are therefore required, which in addition to measures of reproductive barrier strength and selfing rate should routinely include estimates of demographic history and genetic divergence as a proxy for divergence time.

The head of one of the world's largest oil companies has had it with government flip-flopping.

UPDATES: Senator Nick Xenophon said it doesn’t make sense for the agreement between the Liberal and National parties to be kept as a private secret.

Robert joins the cast again as Alex, Anna Marie, and Chris get ready for Extra Life 2020! There’s a lot of embargoed gaming going on this week, but we still manage to round up all the important news of the week for your entertainment. We’re counting down to November 7th with plenty of enthusiasm.

The post RPG Cast – Episode 559: “He Doesn’t Seem to Be Dead?” appeared first on RPGamer.

Jonathan Stringer joins us in an attempt to sell his copy of Mugen Souls. Josh is launching his Kickstarter for his new documentary, Legacy of the Bitcoins. And Chris has lost his Epic Games launcher, thanks Windows 11.

The post RPG Cast – Episode 616: “Garland Does It His Way” appeared first on RPGamer.

Chris's 3DS battery is swol. Johnathan educates us on the retro market. Kelley poopsocks like a three-legged kitten. While Josh waxes poetic about his Madden otome dating sim.

The post RPG Cast – Episode 640: “Does Your Task Bar Need Fiber?” appeared first on RPGamer.

Robert finds out what Godzilla sushi tastes like. Josh pimps his Segway. Phil has a pictomancer at home. The awards all Chris's fault, because he didn't vote. Also, PoE is to Chris, as CoH is to Phil.

The post RPG Cast – Episode 710: “Xenoblade Chronicles X Doesn’t Love You Back” appeared first on RPGamer.

The mystery surrounding Deadlock, Valve’s work-in-progress MOBA shooter, has largely evaporated. Its freely extendable invite system is about as effective at controlling player headcount as a disinterested football steward, meaning pretty much anyone with a clued-in Steam friend can get in and start poking around its secrets. And yet, being a lane-pushing wizard fighter in the Dota 2 vein, it’s already a vast tangle of interplaying abilities, items, strats, and often unspoken rules, of the kind that even experienced gankists will take hundreds of hours to learn. It’s been too much for poor Brendy, at any rate.

Still, Brendy is but one man. What if we had but four men, working in tandem to crush lanes and flatten Patrons just as Gabe intended? To find out if Deadlock is indeed more comprehensible as a team sport, Graham, Ed, Ollie, and James joined forces, promptly getting fucked up yet emerging from the warlock hospital with a deeper understanding of its workings. Or, at least, if anyone would keep playing.

Read more

In America, there’s a significant kind of public insistence that one’s “freedom” is fundamentally tied to one’s wealth.

Much of the country views America through an aspirational and transformative lens, a colorblind and bias-free utopia, wherein wealth conveys equality and acts as a panacea for social and racial ills. Once an individual achieves massive financial success, or so the message goes, he or she will “transcend” the scourge of economic and racial inequality, truly becoming “free.”

Working in parallel with this reverence for this colorblind version of the “American Dream” is the belief that economic privilege mandates patriotic gratitude. Across industries and disciplines, Americans are told to love their nation uncritically, be thankful that they are exceptional enough to live in a country that allows citizens the opportunity to reach astronomical heights of economic prosperity.

For the nation’s black citizens, there’s often an additional racialized presumption lurking under the surface of these concepts: the notion that black success and wealth demands public silence on systemic issues of inequality and oppression.

These are durable and fragile ideologies that prop up the concept of the American Dream – durable because they are encoded in the very fabric of American culture (most Americans, including African Americans, have readily embraced these ideologies as assumed facts); yet fragile because it’s all too easy to see that one’s economic privilege is a lousy barrier against both individual and systemic discrimination and oppression.

Consequently, black people have also been among the most vocal challengers of these ideologies, as we’ve seen most recently with the Colin Kaepernick and the NFL #TakeAKnee demonstrations. In a show of solidary with the free agent quarterback, professional football players – the vast majority of whom are black – have been kneeling during the National Anthem as a means of protesting racial injustice and police brutality.

WATCH: NFL players team up in defiance and solidarity

Over the past few weeks, the president of the United States has brought renewed attention to the inherent tensions that define the ideologies of the “American Dream” through his repeated public criticisms of these kneeling NFL players.

“If a player wants the privilege of making millions of dollars in the NFL, or other leagues,” Trump recently tweeted, he or she should not be allowed to kneel. Labeling the protestors actions “disrespectful” to the country, flag and anthem, President Donald Trump has called for players to be fired, encouraged a boycott of the NFL, insisted that the league pass a rule mandating that players stand for the anthem and derided the protestors as “sons of bitches.”

In a dramatic ploy more befitting of a scripted reality television show, the president gloated that he had instructed Vice President Mike Pence to walk out of an Indianapolis Colts game the moment any player kneeled. This was an orchestrated show of power and outrage, designed to send a flamboyant political message given that Trump and Pence knew in advance that on that particular day, the Colts were playing the San Francisco 49ers – the team that currently has the most protestors. The NFL’s announcement this week that the league has no plans to penalize protesting players is the most recent event to provoke the president’s fury; taking to social media during the early morning, he once again equated kneeling with “total disrespect” for our country.

As many have pointed out, the president’s moralizing outrage toward the NFL players is selective and deeply flawed – his apparent patriotic loyalty hasn’t stopped the billionaire politician from criticizing the removal of Confederate statues, or attacking a Gold Star family, or mocking Sen. John McCain’s military service.

The NFL players and their defenders have repeatedly stated that the protests are intended to highlight racial inequality and oppression. They’ve also explained that their decision to kneel emerged from a desire to protest peacefully and respectfully after a sustained conversation with military veterans.

Trump has chosen to ignore these rationales and the structural issues of inequality that motivate the protests and instead, advance a narrative exclusively concerned with overt displays of American patriotism and the “privilege” of the NFL players. As one of president’s advisors explained, by aggressively targeting the NFL players, Trump believes that he is “winning the cultural war,” having made black “millionaire sport athletes his new [Hillary Clinton].”

READ MORE: As ‘America’s sport,’ the NFL cannot escape politics

It’s a cynical statement, revealing the president’s perception of the jingoism of his base of supporters who envision him as a crusader for American values and symbols.

In casting the black protestors as the antithesis of all of this, Trump has marked the players as unpatriotic elites and enemies of the nation. For a president who has consistently fumbled his way through domestic and foreign policy since he was elected, a culture war between “hard-working” and “virtuous” working-class and middle-class white Americans and rich, ungrateful black football players is a welcome public distraction.

Trump’s attacks on the NFL protestors are rooted in those competing tensions inherent to the American Dream: that wealth equals freedom; that economic privilege demands patriotic gratitude; and most importantly, that black people’s individual economic prosperity invalidates their concerns about systemic injustice and requires their silence on racial oppression.

Among the protestors’ detractors, this has become a common line of attack, a means of disparaging the black NFL players’ activism by pointing to their apparent wealth. The fact that systemic racism is demonstrably real and that individual prosperity does not make one immune to racial discrimination appears to be lost on the protestors’ critics.

Theirs is a grievance that suggests that black athletes should be grateful to live in this country; that racism can’t exist in America since black professional athletes are allowed to play and sign contracts for considerable sums of money; that black players owe the nation their silence since America “gave” them opportunity and access; that black athletes have no moral authority on issues of race and inequality because of their individual success; and that black athletes’ success was never theirs to earn, but instead, was given to them and can just as easily be taken away.

This culture war being waged over black athletes is not new. Black athletes – and entertainers – have long been hyper-aware of their peculiar place in American society as individuals beloved for their athletic and artistic talents, yet reviled the moment they use their public platform to protest systemic racial inequality. The parallels between the #TakeAKnee protests and the protests of Muhammad Ali or John Carlos and Tommie Smith are readily apparent; so too are there important similarities to the case of Paul Robeson.

An outspoken civil rights activist, collegiate and professional football player, lawyer, opera singer and actor, Robeson had his passport revoked in 1950 because of his political activism and speech – actions that all but destroyed his career. The star athlete and entertainer, “who had exemplified American upward mobility” quickly “became public enemy number one” as institutions cancelled his concerts, the public called for his death and anti-Robeson mobs burned effigies of him.

During a 1956 congressional hearing, the chairman of the House Committee on Un-American Activities beat a familiar refrain with Robeson, challenging the entertainer’s accusations of American racism and racial oppression. He saw no sign of prejudice, he argued, since Robeson was privileged, having gone to elite universities and playing collegiate and professional football.

READ MORE: Poll: Americans divided on NFL protests

Black athletes, even the silent ones, largely understand that their economic privilege doesn’t insulate them from the realities of racial discrimination. They also understand that their wealth and success is precarious and is often dependent not only upon their athletic performance, but also upon them remaining silent on issues of racial injustice, especially those that appear to question the “American Dream” or implicate the American public by association.

It should come as no surprise then that Colin Kaepernick, whose protests turned him into a national pariah despite his on-the-field talents, has filed a grievance against the NFL, accusing the league and its teams of blackballing him because of his political beliefs. “Principled and peaceful political protest,” Kaepernick’s lawyers argued in a statement, “should not be punished and athletes should not be denied employment based on partisan political provocation by the Executive Branch of our government.” Whether the ostracized Kaepernick will win his grievance is unknown, but it is certainly telling that he and his lawyers have rooted their claims in contested definitions of freedom and the precarious economic privilege of outspoken NFL players.

For the loudest and most vocal critics of black protestors, in particular, outspokenness is tantamount to treason, grounds for the harshest of punishments. Perhaps they would benefit from a close reading of James Baldwin, who once argued: “I love America more than any other country in this world, and, exactly for this reason, I insist on the right to criticize her perpetually.”

The post Column: For black athletes, wealth doesn’t equal freedom appeared first on PBS NewsHour.

General relativity teaches us that observing a black hole is all a question of perspective – and technique, says Chanda Prescod-Weinstein

In order to figure out how something came from nothing, we first need to explore the different types of nothing

Other Democrats lambasted him. The Tufts political science department spurned him. But Moulton is raising concerns the left needs to take seriously.

Scientists have recreated the scent of the embalming fluid used to preserve a noblewoman more than 3,500 years ago — and they say it's quite lovely, indeed.

Red and processed meat, and even poultry, seem to raise the risk of developing type 2 diabetes, according to a study of nearly 2 million adults, but not everyone is convinced

Amid rising cases of mpox in Central Africa, it is important to uncover whether this virus causes symptoms even after the infection has cleared

A network of neurons in the brain seems to be larger in people with depression, which could change how we think about the condition's causes

A bird flu virus that has been circulating in dairy cattle for months has now been found in a pig in the US for the first time, raising the risk of the virus evolving to become more dangerous to people

'Gutfeld!' panelists react to President-elect Trump's choice for 'border czar.'

Researchers say tornadoes in Harvey, Sheffield areas on Friday evening were record-breaking for the province.

And the Senate shouldn’t abandon its ‘advice and consent’ role.

Following a mother and son during the the Blitz, Nazi Germany's bombing campaign on London during the Second World War, director Steve McQueen's new drama understands the war film — perhaps a bit too well.

No, but the direction of our hair whorls could teach us about human development

“Going viral” appears to be more than just a catchphrase when it comes to the rampant spread of misinformation

The U.S. Food and Drug Administration posted a video:

What happens after a drug is approved? And how and why do drug recalls happen? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

What happens after a drug is approved? And how and why do drug recalls happen? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

Prescription drugs go through many steps and phases before they’re approved by the FDA, from research to clinical trials. What does this process look like from beginning to end? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

Prescription drugs go through many steps and phases before they’re approved by the FDA, from research to clinical trials. What does this process look like from beginning to end? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).