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Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film and method of forming pattern

Provided is an actinic-ray- or radiation-sensitive resin composition including (A) a compound that when exposed to actinic rays or radiation, generates an acid, (B) a resin that when acted on by an acid, increases its rate of dissolution in an alkali developer, and (C) a hydrophobic resin, wherein the hydrophobic resin (C) contains a repeating unit derived from any of monomers of general formula (1) below.




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Photosensitive composition comprising an acrylate compound

The present invention relates to a photosensitive composition including an acrylate-based compound having an adamantyl structure. It is possible to manufacture an organic thin film that is easily stripped without decreasing the strength of the thin film by using the photosensitive composition.




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Positive photosensitive resin composition, photosensitive resin film prepared by using the same, and semiconductor device including the photosensitive resin film

Disclosed is a positive photosensitive resin composition that includes (A) an alkali soluble resin prepared by a phosphorous-containing diamine represented by the following Chemical Formula 1, (B) a photosensitive diazoquinone compound, and (C) a solvent. A photosensitive resin film prepared using the same and a semiconductor device including the photosensitive resin film are also disclosed. In Chemical Formula 1, each substituent is the same as defined in the detailed description.




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Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member

Provided are an electrophotographic photosensitive member in which leakage doesn't easily occur, a process cartridge and an electrophotographic apparatus each including the electrophotographic photosensitive member, and a method of manufacturing the electrophotographic photosensitive member. The electrophotographic photosensitive member includes a conductive layer including titanium oxide particle coated with tin oxide doped with a hetero element. When an absolute value of a maximum current amount flowing through the conductive layer in a case of performing a test of applying −1.0 kV including DC voltage to the conductive layer is defined as Ia, and an absolute value of a current amount flowing through the conductive layer in a case where a decrease ratio of a current amount per minute reaches 1% or less for the first time is defined as Ib, the relations of Ia≦6000 and 10≦Ib are satisfied. A volume resistivity of the conductive layer before the test is 1.0×108 Ω·cm to 5.0×1012 Ω·cm.




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Solution of gallium phthalocyanine method for preparing the same method for producing gallium phthalocyanine crystal method for purifying composition containing gallium phthalocyanine and method for producing electrophotographic photosensitive member

A solution of a gallium phthalocyanine contains a compound of formula (1) and a gallium phthalocyanine of formula (2), H2N—CH2—R1—CH2—NH2 (1) wherein R1 represents a single bond, or a substituted or unsubstituted alkylene group having 1 to 10 main-chain carbon atoms, a substituent of the substituted alkylene group is an alkyl group having 1 to 3 carbon atoms, an alkyl group having 1 to 3 carbon atoms and being substituted with an amino group, or a hydroxy group, one of the carbon atoms in the main chain of the alkylene group may be replaced with an oxygen atom, a sulfur atom, or a bivalent group represented by the formula —NR2—, and R2 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an alkyl group having 1 to 3 carbon atoms and being substituted with an amino group, and wherein X1 represents a chlorine atom or hydroxy group.




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Radiation-sensitive resin composition, method for forming resist pattern, and polymer and compound

A radiation-sensitive resin composition that provides a resist coating film in a liquid immersion lithography process is provided, the radiation-sensitive resin composition being capable of exhibiting a great dynamic contact angle during exposure, whereby the surface of the resist coating film can exhibit a superior water draining property, and the radiation-sensitive resin composition being capable of leading to a significant decrease in the dynamic contact angle during development, whereby generation of development defects can be inhibited, and further shortening of a time period required for change in a dynamic contact angle is enabled. A radiation-sensitive resin composition including (A) a fluorine-containing polymer having a structural unit (I) that includes a group represented by the following formula (1), and (B) a radiation-sensitive acid generator.




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Method for forming patterns of semiconductor device by using mixed assist feature system

A method for forming patterns of a semiconductor device includes providing a photomask that includes an array of contact holes in an active region, a plurality of first dummy contact holes for restricting pattern distortion of the contact holes in an area outside of the array of the contact holes, a plurality of first assist features for restricting pattern distortion of the first dummy contact holes disposed inside a corresponding one of the first dummy contact holes, and an array of second assist features for additionally restricting pattern distortion of the first dummy contact holes. The array of second assist features is disposed outside of the first dummy contact holes. The method also includes forming an array of contact holes and first dummy contact holes on a wafer by using the photomask as an exposure mask.




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Method of producing gallium phthalocyanine crystal and method of producing electrophotographic photosensitive member using the method of producing gallium phthalocyanine crystal

Provided is a method of producing an electrophotographic photosensitive member having improved sensitivity and capable of outputting an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The method of producing a gallium phthalocyanine crystal includes subjecting a gallium phthalocyanine and a specific amine compound, which are added to a solvent, to a milling treatment to perform crystal transformation of the gallium phthalocyanine. In addition, the gallium phthalocyanine crystal is used in the photosensitive layer of the electrophotographic photosensitive member.




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Mask blank, transfer mask, method of manufacturing a transfer mask, and method of manufacturing a semiconductor device

A mask blank for use in the manufacture of a binary mask adapted to be applied with ArF excimer laser exposure light has, on a transparent substrate, a light-shielding film for forming a transfer pattern. The light-shielding film has a laminated structure of a lower layer and an upper layer and has an optical density of 2.8 or more for exposure light and a thickness of 45 nm or less. The lower layer is made of a material in which the total content of a transition metal and silicon is 90 at % or more, and has a thickness of 30 nm or more. The upper layer has a thickness of 3 nm or more and 6 nm or less. The phase difference between exposure light transmitted through the light-shielding film and exposure light transmitted in air for a distance equal to the thickness of the light-shielding film is 30 degrees or less.




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Quick-release cymeal mounting fastener

A fastener for quick-mounting a cymbal to an upright cymbal support rod comprising a pair of half-round sleeve members arranged in face-to-face relationship forming a cylindrical surface therebetween for grasping the cymbal mounting rod; a tab extending upward from each sleeve member including means for pivoting said members near said tabs so that, by squeezing said tabs together, said sleeve members are pivoted away from each other; a pair of split flange members, one attached to the lower end of each sleeve member, spaced apart from said tab, arranged in co-planar alignment when said members are in adjacent contact to form a planar compression surface for pressing toward a cymbal placed on the cymbal mounting rod; and, means for biasing said sleeve members into full contact about the cymbal mounting rod threaded end to hold the cymbal on the rod.




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Method and apparatus for representing musical information

A method for electronically processing and storing musical information involves separating the musical information into a plurality of segments, each representing some portion of a measure, and assigning a sequential time dimension value to each segment. The musical information is also separated into plurality of channels, with each channel representing a sound source and having a sound dimension value assigned to it. The musical information for a given channel and segment is stored in a memory array by associating the musical information corresponding to a given channel and segment with the memory array node specified by the time dimension value and sound dimension value assigned to the given channel and segment.




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Structure of rotary valve assembly used in wind instrument

A rotary valve assembly incorporated in a brass instrument for changing a pitch of a tone comprises a rotary valve housed in a valve casing having two groups of aeroports, and the rotary valve is provided with two air passages, one of which interconnects the aeroports in the first group and the other of which interconnects one aeroport of the first group and one aeroport of the second group, so that various arrangements are possible for the aeroports.




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Keyboard with multiple indicia sets

The present invention discloses a method for displaying individually on a plurality of keys of a keyboard or keypad two or more indicia representing two or more functions performed by each key. The keys are characterized in that each of the two or more indicia is provided on the key in a plurality of separated portions. The portions being positioned in a spaced positioned relationship with one another, so as not to be physically closely juxtaposed. When viewed at a predetermined angle all parts of the indicia are optically juxtaposed to create the entire indicia.




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Pedal assembly for musical instruments

A pedal assembly for a bass drum or high hat cymbals. A flat base plate has a resilient pedal board clamped to it with the pedal board inclined to receive a foot. A beater stick is connected with the toe end of the pedal board by a linkage that drives the beater stick against a bass drum when the pedal is depressed. The resiliency of the pedal board returns it to its normal position when foot pressure is withdrawn. The material of which the pedal board is constructed has a modulus of elasticity between about one million and about six million. A striker pad limits the depression of the pedal board to limit the force that the beater stick can apply to the drum.




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Method for performing handover, user equipment, base station, and radio communication system

Provided is a method for performing a handover from a first base station to a second base station by a user equipment that is performing a radio communication over a communication channel formed by aggregating a plurality of component carriers. The method includes a step of transmitting a handover command for a component carrier for which a handover has been approved by the second base station among the plurality of component carriers from the first base station to the user equipment and a step of trying to make an access from the user equipment to the second base station for each component carrier in response to the handover command.




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System and method for mode-based social networking

A mode-based method of social networking comprising storing in a database profile information for a plurality of users, event information for a plurality of events and a mode associated with each event, receiving by a plurality of computerized user devices a selection of a mode and one or more geographic proximity parameter selections from a each of plurality of users, displaying, event information for an event having a same mode as the first user, profile information for one or more other users among the plurality of users having selected the same mode as the first user and located within a geographic proximity parameter selected by the first user, and a density of a plurality of users located within the geographic proximity parameter selected by the first user wherein the density is represented by a color corresponding to the mode.




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Network connection segment monitoring

An example method transmits a path message to an egress node, via intermediate nodes, that configures OAM monitoring of an entire connection between an ingress node and the egress node and also configures OAM monitoring of at least one segment of the connection shorter than the entire connection by at least one intermediate node. The path message comprises a LSP attributes object and an ERO. The LSP object comprises technology-specific attributes defining descriptors for configuring the egress node in accordance with a communication protocol utilized for the connection; and technology-independent OAM parameters that, irrespective of the communication protocol, define an OAM type to be used by the egress node, and define desired monitoring actions for the egress node to perform. The ERO comprises a respective HOP Attributes sub-object for configuring each of the at least one intermediate nodes. Each HOP Attributes sub-object also comprises technology-specific attributes and technology-independent OAM parameters.




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Distributed management with embedded agents in enterprise apps

Distributed mobile device management including a plurality of management agents is disclosed. Management-related information may be retrieved from a storage location accessible to a plurality of management agents. The management-related information may have been provided to the storage location from a management agent associated with a managed application. And at least one operation may be performed based at least in part on the management-related information.




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System and method for protecting data in an enterprise environment

Provided are a system and method for protecting data in an electronic communications environment. An interested entity establishes one or more controls for a received unit of data. At a source device in the electronic communications network, the unit of data is encapsulated with self-protection security data that includes the one or more controls. The encapsulated unit of data is delivered from the source device to a destination device in the electronic communications network. A data broker facilitates the delivery of the data to the destination device according to the controls. Facilitating the delivery of the data includes: identifying for the receiving device a collection of services corresponding to the controls independently of the network.




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System for streaming using mobile devices and servers

A method and apparatus in which multiple Internet Protocol (IP) based wireless data transmissions are simultaneously provided between a wireless device and a server, including providing multiple antennas, multiple T/R units, multiple processors and multiple I/O ports on the wireless device. The method includes receiving multiple IP data packets on the I/O ports at substantially the same time, and sending multiple data packets from the wireless device to the server, whereby the transmission rate between the wireless device and the server is increased.




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MU-MIMO-OFDMA systems and methods for servicing overlapping co-scheduled users

Methods and systems for conveying or transmitting to any given user in an OFDMA-MU-MIMO system scheduling information of other co-scheduled users to permit the user to perform error-correction on received data and/or interference reduction on its received signals. The scheduling information can include resource block assignment, modulation constellations employed, coding rates employed, power levels utilized and precoder matrix indices used. Further, the scheduling information can be conveyed in part through dedicated reference symbol layers or pilot streams. Moreover, a base station may transmit a preliminary estimate of the total number of users the base station expects to schedule, or an upper-bound on the total number of users, to the MU-MIMO users to permit the MU-MIMO users to determine preferred precoder matrix indices and indications of channel quality indices.




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Quality of service application controller and user equipment application profiler

Various topologies of a quality of service application controller and related techniques to optimize the communications performance an application executing on a device participating in a communications environment are disclosed. The communications environment may include a cellular network, an unlicensed spectrum network, or a combination of the two. The quality of service application controller observes one or more key performance indicators of the communications network, and retrieves a policy from a policy store specific to the application. The quality of service application controller then modifies the execution of the application and/or the configurable aspects of the communications environment to optimize the communications performance of the application. For example, the application's data throughput may be increased, the power draw of the application may be minimized, data requested by the application may be minimized, or the apparent response time of the application's response to a web service may be minimized.




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Mobile user terminal, mobile communication system, base station, and communication method

A mobile user terminal, which communicates with a base station in an intermittent fashion, the mobile user terminal includes a radio transmitter which transmits downlink channel quality information indicating downlink channel quality and an uplink pilot signal to a base station in an intermittent fashion; and a transmit time controller which synchronizes transmit time of the downlink quality information and transmit time of the uplink pilot signal relative to each other, such that the downlink quality information and the uplink pilot signal are sent in adjacent different timings in a period corresponding to a state of intermittent communicate.




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Treadle-drive eccentric wheel transmission wheel series with periodically varied speed ratio and having inward packing auxiliary wheel

In the present invention, one or both of an active wheel or a passive wheel is composed of an eccentric transmission wheel and is combined with a synchronous transmission belt for forming an eccentric wheel transmission wheel series, so that when the feet input forces at different angles from the treadle shafts of the treadles to an active wheel shaft combined on the active wheel through cranks, the active wheel forms different transmission speed ratios relative to the passive wheel according to the treadle angle, and random inward packing is performed to the transmission belt (100) of the engage end of the eccentric passive wheel (413) during the transmission for stabling the operation.




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Seal arrangement and hinge of a chain with the seal arrangement

A sealing arrangement used to create a seal between a first part of a chain and a second part of the chain, wherein the second part can at least be pivoted in relation to the first part, includes a sealing ring with an annular sealing lip for sealing a lubricant area between parts which can be pivoted towards each other, and an elastic ring which is adapted to be fixed to one of the parts and which is adapted to exert pressure in the sealing ring. In addition, a supporting ring is arranged between the sealing ring and the elastic ring.




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Utility vehicle with a continuously variable transmission having a system for selectively establishing a fixed maximum transmission ratio

A continuously variable transmission for a vehicle comprises a primary pulley, a secondary pulley, and a belt entrained around both pulleys in an opposite manner between the fixed and movable sheaves thereof. One pulley carries a selectively deployable stop that may be placed into position to mechanically limit the range of motion between the fixed and movable sheaves. This establishes an actual maximum transmission ratio that is larger than the nominal minimum transmission ratio but smaller than the nominal maximum transmission ratio achievable by the transmission during normal operation thereof. When such a transmission is used on a utility vehicle attached to a substance dispensing applicator operatively driven by the vehicle's engine, the application rate stays substantially constant despite changes in engine speed when the user keeps the transmission upshifted to the actual maximum transmission ratio set by the position of the deployed stop.




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Bicycle sprocket for use with a multi-gear rear cassette

A rear bicycle sprocket for use with a multi-gear rear cassette is provided. The sprocket includes a chain engaging portion and a mounting portion having generally annular shape about a central axis and a plurality of support arms, integrally formed with the chain engaging portion and with the mounting portion. The sprocket further includes a plurality of space maintaining protrusions, each space maintaining protrusion extending axially forwardly from an axially forward surface of a corresponding support arm and integrally formed therewith. A multi-gear rear cassette having a plurality of sprockets coaxially mounted together wherein the plurality of sprockets includes the rear bicycle sprocket mounted axially rearmost and a bicycle including the multi-gear rear cassette are further provided.




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Arrangement for lube oil supply a chain drive driving a transmission oil pump arranged offset the axis of a torque converter

An arrangement for supplying oil to a chain drive which drives a transmission oil pump that is axially offset relative to a torque converter and embedded in an intermediate plate in a vehicle having a torque converter. The driven sprocket of the chain drive is supported by a converter neck mounted in a centering plate. A seal is provided between the converter neck and the sprocket and is arranged adjacent the sliding fit between the converter neck and the sprocket. To compensate for the suppression of lubrication of the seal, the neck bearing and the chain drive, a valve is integrated in the intermediate plate, and a duct is provided in the plane, in which the centering plate is screwed to the intermediate plate, such that excess oil flowing from the valve is selectively directed to the seal, the neck bearing and the chain drive.




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Hydraulic damping mechanism and use for belt tensioning

A hydraulic damper for providing fluid damping to a tensioner in a drive system that includes a damper cup, which is mounted to the tensioner and configured to rotate about a central axle in tandem with the tensioner, an end plate having an outer face and an inner face, which is attached to the damper cup forming a fluid chamber, a peg attached to the end plate and extending away from the inner face and toward the damping cup, a damping fluid, which is contained within the fluid chamber, a plurality of shear plates housed within the fluid chamber comprising alternating fixed plates engaged with a fixed component of the tensioner and rotatable plates engaged with a rotatable component of the tensioner where the peg extends through openings in each of the shear plates allowing for rotation of the rotatable plate with the rotation of the peg.




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Recirculating ball screw assembly

Ball screws are described that may be incorporated into other devices such as a pulley assembly or a differential device. The ball screws include a threaded shaft defining a central longitudinal axis with a threaded nut threadedly coupled thereto to define at least one track in between them. Each track forms a continuous loop around an infield protrusion and is filled with a plurality of rolling elements filling. Each rolling element has the same radius from the central longitudinal axis such that the nut can rotate at higher speeds without the rolling elements locking up as a result of centripetal force.




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Secondary assembly drive of an internal combustion engine and method for operating same

A secondary assembly drive of an internal combustion engine and a method for operating same are provided. The secondary assembly drive includes: a first drive wheel (1) which can be rotatably connected to a crank shaft (CR) of the internal combustion engine, an electric machine which can be operated either as a generator (AL) of as a motor (M) and a second drive wheel (2) which can be rotatably connected to the electric machine (AL, M), an air-conditioning compressor (A/C) and a third drive wheel (3) which can be rotatably connected to the air-conditioning compressor, a traction element (4) which rotates infinitely and which wraps around the drive wheels, and an actuable clutch (7) for disconnecting the drive of the electric machine and of the air-conditioning compressor from the crankshaft when necessary. In addition, the air-conditioning compressor is designed for operation in both rotational directions, and a reversal of the rotational direction between the generator operating mode and the motor operating mode of the electric machine is provided.




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Method for electronically controlling a bicycle gearshift and electronically servo-assisted bicycle gearshift

A method for electronically controlling a bicycle gearshift comprising at least one derailleur is disclosed, comprising the sequential steps of: a) imparting a movement on the derailleur of the gearshift until the derailleur is in an intended position;b) waiting for a predetermined time period,c) performing a check whether the derailleur is in the intended position, within a possible predetermined tolerance,d) in case said check has a negative outcome, imparting a movement on the derailleur of the gearshift until the derailleur is in the intended position. A derailleur and an electronically servo-assisted bicycle gearshift comprising control electronics comprising modules adapted to carry out the method outlined above are also disclosed.




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Secondary assembly drive of an internal combustion engine and method for operating same

A secondary assembly drive of an internal combustion engine and a method for operating same are provided. The secondary assembly drive includes, in two drive planes, an assembly drive (2) and a starter drive (12) and permits, in addition to a normal operating mode, the following operating modes: —starting of the internal combustion engine, —boosting of the internal combustion engine, —air-conditioning, and —deactivation of the assembly drive (2).




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Treadle-drive eccentric wheel transmission wheel series with periodically varied speed ratio

The present invention is structured by using one or both of an active wheel and a passive wheel being composed of an eccentric transmission wheel and being combined with a synchronous transmission belt for forming an eccentric wheel transmission wheel series, so that in the reciprocal treadle performed by the human's feet, when the feet input forces at different angles from the treadle shafts of the treadles to an active wheel shaft combined on the active wheel through cranks, the active wheel forms different transmission speed ratios relative to the passive wheel according to the treadle angle.




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Plants and seeds of corn variety CV052803

According to the invention, there is provided seed and plants of the corn variety designated CV052803. The invention thus relates to the plants, seeds and tissue cultures of the variety CV052803, and to methods for producing a corn plant produced by crossing a corn plant of variety CV052803 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV052803 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV052803.




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Modalities for the treatment of degenerative diseases of the retina

This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.




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Nonhuman mammal whose mtDNA is from a nonhuman mammal resistant to a selected disease or disorder and whose nDNA is from a nonhuman donor mammal more susceptible to the selected disease or disorder

Provided herein are mitochondrial-nuclear exchanged cells and animals comprising mitochondrial DNA (mtDNA) from one subject and nuclear DNA (nDNA) from a different subject. Methods for producing a mitochondrial-nuclear exchanged animal and animals made by the methods are provided. Also provided are methods of screening for agents useful for treating a disease or disorder using mitochondrial-nuclear exchanged animals or cells, tissues or organs thereof.




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Method for modifying plant architecture and enhancing plant biomass and/or sucrose yield

The present invention relates to methodology and constructs for modifying plant architecture and enhancing plant biomass and/or sucrose yield.




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Plants and seeds of canola variety SCV435009

In an embodiment, the invention relates to the seeds, plants, and plant parts of canola variety SCV435009 and to methods for producing a canola plant produced by crossing canola variety SCV435009 with itself or with another canola variety. The invention also relates to methods for producing a canola plant containing in its genetic material one or more transgenes and to the transgenic canola plants and plant parts produced by those methods. This invention also relates to canola varieties or breeding lines and plant parts derived from canola variety SCV435009, to methods for producing other canola varieties, lines or plant parts derived from canola variety SCV435009 and to the canola plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid canola seeds, plants and plant parts produced by crossing the variety SCV435009 with another canola variety.




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Plants and seeds of hybrid corn variety CH715413

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH715413. The invention thus relates to the plants, seeds and tissue cultures of the variety CH715413, and to methods for producing a corn plant produced by crossing a corn plant of variety CH715413 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH715413.




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Non-glycosylated transferrin expressed in monocots

Disclosed are compositions and methods of making non-glycosylated transferrin protein in transgenic monocot plants.




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Mixing device for creating an output mixture by mixing a first material and a second material

A mixing device for mixing a first and second material together to create an output mixture. The device includes a first chamber containing the first material coupled to a mixing chamber defined between a rotor and a stator. The rotor is disposed inside the stator and rotates therein about an axis of rotation. The first chamber houses an internal pump configured to pump the first material from the first chamber into the mixing chamber. The pump may be configured to impart a circumferential velocity into the first material before it enters the mixing chamber. At least one of the rotor and stator have a plurality of through-holes through which the second material is provided to the mixing chamber. Optionally, a second chamber is coupled to the mixing chamber. The second chamber may house an internal pump configured to pump the output material from the mixing chamber into the second chamber.




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Sequential start clutch for a material mixing machine

A mixer system includes a mixing chamber with a drive panel, open top, discharge opening in a side of the mixing chamber, and door configured to open and close the discharge opening. A first mixing auger is disposed inside the mixing chamber, and a first auger drive is disposed on another side of the drive panel and connected to the first auger through the drive panel and connected to a driveline. A second mixing auger is disposed inside the mixing chamber on the first side of the drive panel, and another auger drive is connected to the second auger through the drive panel. A clutch is connected between the second auger drive and the driveline and configured to mechanically connect and disconnect the second auger drive from the driveline based on an input. A method of sequentially starting different augers within a mixing chamber is provided.




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Cell culture and mixing vessel

A mixing vessel (10) for containing a liquid, comprises a chamber having a lower chamber portion and an upper chamber portion wider than the lower portion, gas inlet means (14) for supplying gas to the lower portion and means for redirecting rising gas (24), such that, in use, rising gas in the form of bubbles, initially rises substantially vertically and is redirected in a substantially horizontal direction by the means for redirecting rising gas.




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Eddy current minimizing flow plug for use in flow conditioning and flow metering

An eddy-current-minimizing flow plug has an outer radial wall with open flow channels formed between the plug's inlet and outlet. The plug has a central region coupled to the inner surface of the outer radial wall. Each open flow channel includes (i) a first portion originating at the inlet and converging to a location in the plug where convergence is contributed to by changes in thickness of the outer radial wall and divergence of the central region, and (ii) a second portion originating in the plug and diverging to the outlet where divergence is contributed to by changes in thickness of the outer radial wall and convergence of the central region. For at least a portion of the open flow channels, a central axis passing through the first and second portions is non-parallel with respect to the given direction of the flow.




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Apparatus for mixing and controlling the temperature of laboratory vessel contents

The present invention relates to an apparatus for mixing and controlling the temperature of laboratory vessel contents with an accommodating device in detachable connection with an exchangeable block for accommodating and controlling the temperature of laboratory vessels and with a drive by which the accommodating device can be set in a mixing motion, and with a temperature control device with a heat source or sink in heat-conducting connection with the exchangeable block at least through in each case at least one adjoining contact face firstly on the accommodating device and secondly on the exchangeable block, which is characterized in that the detachable connection is maintained by a spring element which, by virtue of its spring force, horizontally clamps together a first undercut between the accommodating device and the exchangeable block in at least one first direction.




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Seal ring

A seal ring is provided which allows the interior of a cylinder 1 of a screw extruder to be maintained at elevated temperature and elevated pressure, thus suppressing a variation in the pressure in the cylinder 1. In a special seal ring 300 attached to a screw shaft 7 in the cylinder of the screw extruder so as to be rotatable integrally with the screw shaft 7, thus restraining a material to be treated from being fed from upstream to downstream in the cylinder, a lead groove 317 extending in an axial direction of the shaft 7 is formed in an outer circumferential surface 316 opposing with a predetermined gap to an inner circumferential surface 1a of the cylinder. The lead groove 317 serves to disturb the flow of the material to be treated passing between the outer circumferential surface 316 and the inner wall surface 1a of the cylinder 1 to complex the flow. This stabilizes feeding resistance to suppress a variation in the pressure in the cylinder 1.




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Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use

This disclosure is directed to pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder. The compounds may bind to and antagonize receptor α2B, α1B or α2A. The compounds may find use in therapy, e.g., to (i) reduce blood pressure and/or (ii) promote renal blood flow and/or (iii) decrease or inhibit sodium reabsorption, or to regulate blood glucose level, increase insulin secretion and treat diseases or conditions that are, or are expected to be, responsive to an increase in insulin production. The compounds may also be used to treat diseases or conditions that are expected to be responsive to a decrease in blood pressure. Use of the compounds to treat cardiovascular, renal disorders or type 2 diabetes is particularly described.




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Dihydroethidine analogues and uses thereof

Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.




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Synthesis of MSE-framework type molecular sieves

A method of synthesizing a crystalline molecular sieve having an MSE framework type comprises crystallizing a reaction mixture comprising a source of water, a source of an oxide of a tetravalent element, Y, selected from at least one of silicon, tin, titanium, vanadium, and germanium, optionally a source of a trivalent element, X, a source of an alkali or alkaline earth metal, M, and a source of organic dications, Q, such as 3-hydroxy-1-(4-(1-methylpiperidin-1-ium-1-yl)butyl)quinuclidin-1-ium, 3-hydroxy-1-(5-(1-methylpiperidin-1-ium-1-yl)pentyl)quinuclidin-1-ium, 1,1'-(butane-1,4-diyl)bis(1-methylpiperidin-1-ium), 1,1'-(pentane-1,5-diyl)bis(1-methylpiperidin-1-ium), 1,1'-(hexane-1,6-diyl)bis(1-methylpiperidin-1-ium), and 1,1'-((3as,6as)-octahydropentalene-2,5-diyl)bis(1-methylpiperidin-1-ium).