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Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control

William W. Seeley
Feb 28, 2007; 27:2349-2356
BehavioralSystemsCognitive




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Il faut saisir l'occasion d'assurer une croissance durable, selon la BRI

French translation of BIS press release on the presentation of the Annual Economic Report 2018, 24 June 2018. Les responsables des politiques publiques peuvent prolonger la phase de croissance actuelle en engageant des réformes structurelles, en restaurant les marges de manoeuvre monétaires et budgétaires pour faire face aux menaces futures et en encourageant une mise en oeuvre rapide des réformes réglementaires, indique la Banque des Règlements Internationaux (BRI) dans son Rapport économique annuel. ...




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Soutenir la dynamique de croissance

French translation of speech delivered by Mr Agustín Carstens, General Manager of the BIS, on the occasion of the Bank's Annual General Meeting, Basel, 24 June 2018. Mesdames et Messieurs, j'ai le plaisir de vous présenter aujourd'hui la première édition du Rapport économique annuel de la BRI. Les trois premiers chapitres analysent les évolutions, perspectives et risques de l'économie mondiale, en s'attachant plus particulièrement à la politique monétaire et aux réformes de la réglementation financière, aux marchés et aux acteurs de l'intermédiation. Nous consacrons deux chapitres spéciaux à des enjeux actuels : une analyse des dispositifs macroprudentiels d'une part, une étude relative aux cryptomonnaies d'autre part....




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Les divergences s'accroissent sur les marchés : Rapport trimestriel de la BRI

French translation of the BIS press release about the BIS Quarterly Review, September 2018




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National Engineering Policy Centre to provide advice to government on reaching net zero emissions





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Missed our lecture on Southeast totem parks?




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Ventral Hippocampal Input to the Prelimbic Cortex Dissociates the Context from the Cue Association in Trace Fear Memory

The PFC, through its high degree of interconnectivity with cortical and subcortical brain areas, mediates cognitive and emotional processes in support of adaptive behaviors. This includes the formation of fear memories when the anticipation of threat demands learning about temporal or contextual cues, as in trace fear conditioning. In this variant of fear learning, the association of a cue and shock across an empty trace interval of several seconds requires sustained cue-elicited firing in the prelimbic cortex (PL). However, it is unknown how and when distinct PL afferents contribute to different associative components of memory. Among the prominent inputs to PL, the hippocampus shares with PL a role in both working memory and contextual processing. Here we tested the necessity of direct hippocampal input to the PL for the acquisition of trace-cued fear memory and the simultaneously acquired contextual fear association. Optogenetic silencing of ventral hippocampal (VH) terminals in the PL of adult male Long-Evans rats selectively during paired trials revealed that direct communication between the VH and PL during training is necessary for contextual fear memory, but not for trace-cued fear acquisition. The pattern of the contextual memory deficit and the disruption of local PL firing during optogenetic silencing of VH-PL suggest that the VH continuously updates the PL with the current contextual state of the animal, which, when disrupted during memory acquisition, is detrimental to the subsequent rapid retrieval of aversive contextual associations.

SIGNIFICANCE STATEMENT Learning to anticipate threat from available contextual and discrete cues is crucial for survival. The prelimbic cortex is required for forming fear memories when temporal or contextual complexity is involved, as in trace fear conditioning. However, the respective contribution of distinct prelimbic afferents to the temporal and contextual components of memory is not known. We report that direct input from the ventral hippocampus enables the formation of the contextual, but not trace-cued, fear memory necessary for the subsequent rapid expression of a fear response. This finding dissociates the contextual and working-memory contributions of prelimbic cortex to the formation of a fear memory and demonstrates the crucial role for hippocampal input in contextual fear learning.




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Nestin Selectively Facilitates the Phosphorylation of the Lissencephaly-Linked Protein Doublecortin (DCX) by cdk5/p35 to Regulate Growth Cone Morphology and Sema3a Sensitivity in Developing Neurons

Nestin, an intermediate filament protein widely used as a marker of neural progenitors, was recently found to be expressed transiently in developing cortical neurons in culture and in developing mouse cortex. In young cortical cultures, nestin regulates axonal growth cone morphology. In addition, nestin, which is known to bind the neuronal cdk5/p35 kinase, affects responses to axon guidance cues upstream of cdk5, specifically, to Sema3a. Changes in growth cone morphology require rearrangements of cytoskeletal networks, and changes in microtubules and actin filaments are well studied. In contrast, the roles of intermediate filament proteins in this process are poorly understood, even in cultured neurons. Here, we investigate the molecular mechanism by which nestin affects growth cone morphology and Sema3a sensitivity. We find that nestin selectively facilitates the phosphorylation of the lissencephaly-linked protein doublecortin (DCX) by cdk5/p35, but the phosphorylation of other cdk5 substrates is not affected by nestin. We uncover that this substrate selectivity is based on the ability of nestin to interact with DCX, but not with other cdk5 substrates. Nestin thus creates a selective scaffold for DCX with activated cdk5/p35. Last, we use cortical cultures derived from Dcx KO mice to show that the effects of nestin on growth cone morphology and on Sema3a sensitivity are DCX-dependent, thus suggesting a functional role for the DCX-nestin complex in neurons. We propose that nestin changes growth cone behavior by regulating the intracellular kinase signaling environment in developing neurons. The sex of animal subjects is unknown.

SIGNIFICANCE STATEMENT Nestin, an intermediate filament protein highly expressed in neural progenitors, was recently identified in developing neurons where it regulates growth cone morphology and responsiveness to the guidance cue Sema3a. Changes in growth cone morphology require rearrangements of cytoskeletal networks, but the roles of intermediate filaments in this process are poorly understood. We now report that nestin selectively facilitates phosphorylation of the lissencephaly-linked doublecortin (DCX) by cdk5/p35, but the phosphorylation of other cdk5 substrates is not affected. This substrate selectivity is based on preferential scaffolding of DCX, cdk5, and p35 by nestin. Additionally, we demonstrate a functional role for the DCX-nestin complex in neurons. We propose that nestin changes growth cone behavior by regulating intracellular kinase signaling in developing neurons.




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Introducing TARGET: #ZeroHunger, FAO's new podcast series on global food issues

Radio culture is gaining more and more ground as millions of listeners take to audio podcasts as a convenient and accessible way to learn new information.  Which is why FAO is stepping up into the medium to bring you insights into some of the issues concerning food and agriculture worldwide. Here are the first seven audio offerings of FAO’s new podcast [...]




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(7/18/05) Ignorance is Bliss




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Assembly OKs ‘salmon cans’: Set of policy issue statements that Boro representative will take to D.C. approved




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Holey Cow Product! Swiss Gruyère Claims Cheese Championship

This is the cheesy content readers crave




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Poo-Sniffing Peeps, Miss Ameripeep and More Emerge Victorious in #PeepYourScience 2020 Competition

Blending marshmallows with scientific rigor, the contest offers levity during a difficult time




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Murkowski: Focus is on AK issues: Not on ‘what’s coming up in November’




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Readers Respond to the March 2020 Issue

Your feedback on our coverage of women's history, wolverines and Madame C.J. Walker




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Readers Respond to the April 2020 Issue

Your feedback on our 50th anniversary issue showcasing success stories in conservation




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Eddie Joyce suing Dwight Ball, former colleagues and commissioner for defamation

Independent MHA Eddie Joyce is suing four people, including the premier, for defamation over the handling of a harassment complaint that saw him turfed from the Liberal cabinet and caucus in 2018.



  • News/Canada/Nfld. & Labrador

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Not your stereotypical missionary

From age 17, Ana Maria prayed to serve God in Switzerland. While she waited, she became a dance instructor with no idea dance would become her ministry.




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Afraid of missing out

"Since my childhood, I have been anxious about missing out. I remember not wanting to sleep whenever I heard the adults chatting in the night. I wanted to be part of it all. Later on, in high school, I said “yes” to every event and outing, which ended up crashing so many times. I couldn’t choose. I wanted to be there to celebrate all the fun moments but also share all the tears in the low moments," says Ivy. "However, this lifestyle of being afraid of missing out could not continue when I joined missions. I have had to learn how to let go when I miss out on opportunities to create precious memories with family and friends in my home country."




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Applying Tensile and Compressive Force to Xenopus Animal Cap Tissue

Over many years, the Xenopus laevis embryo has provided a powerful model system to investigate how mechanical forces regulate cellular function. Here, we describe a system to apply reproducible tensile and compressive force to X. laevis animal cap tissue explants and to simultaneously assess cellular behavior using live confocal imaging.




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Basel Committee issues progress report on banks' implementation of the "Principles for effective risk data aggregation and reporting"

BCBS Press release "Basel Committee issues progress report on banks' implementation of the 'Principles for effective risk data aggregation and reporting'", 29 April 2020




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Tissue engineering can play an important role during COVID-19 pandemic

Tissue engineering has a unique set of tools and technologies for developing preventive strategies, diagnostics, and treatments that can play an important role during the ongoing COVID-19 pandemic.




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Truro reeling as recovery effort for missing boy resumes

People in Truro, N.S., are reeling after the disappearance of three-year-old Dylan Ehler as the community tries to come to grips with another potential tragedy in the area.



  • News/Canada/Nova Scotia

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Thomas Jordan: Introductory remarks, Swiss National Bank news conference

Introductory remarks by Mr Thomas Jordan, Chairman of the Governing Board of the Swiss National Bank, at the Media News Conference of the Swiss National Bank, Berne, 25 March 2020.




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RJ Barrett providing 200,000 meals through Mississauga Food Bank

The Mississauga Food Bank says a $100,000 donation made earlier this week by New York Knicks rookie RJ Barrett will provide 200,000 meals as part of the community's fight against the COVID-19 pandemic.



  • Sports/Basketball/NBA

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Raptors' Davis would be 'devastated' if team misses opportunity for playoff run

If the NBA can't salvage the remainder of the season, Terence Davis said he won't be sad for the illustrious complete rookie year that could have been. But he would rue a missed post-season run.



  • Sports/Basketball/NBA

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Claim of unequal pay by U.S. women's soccer team dismissed by judge

A federal judge threw out the unequal pay claim by players on the U.S. women's national soccer team but allowed their allegation of discriminatory travel accommodations and medical support services to go to trial.




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Ottawa teen's 7th annual run for missing and murdered Indigenous women goes virtual

Teenager Theland Kicknosway's annual run for missing and murdered Indigenous women and girls is being turned into a virtual event this year, and he's calling on people from across North America to join him.




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Former CFL star Doug Flutie feels commissioner Ambrosie's pain

Doug Flutie can feel CFL commissioner Randy Ambrosie's pain as Ambrosie continues to discuss potential contingency plans for the 2020 CFL season in response to the COVID-19 pandemic.



  • Sports/Football/CFL

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Evacuation order and alert issued due to landslide risk in Quesnel, B.C., area

An evacuation order and alert have been issued for eight properties near Quesnel, British Columbia, due to risk of a landslide from flooding.



  • News/Canada/British Columbia

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An architect explores using his passion in missions

For years, Gustavo, an architect from Central America, felt drawn to working in the Arabian Peninsula. Then, on a short-term trip, he saw what it could be like to use his profession overseas.




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Not your stereotypical missionary

From age 17, Ana Maria prayed to serve God in Switzerland. While she waited, she became a dance instructor with no idea dance would become her ministry.




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The Governor Who Dissed New Yorkers

I just hate it when my fellow Italian-Americans squabble.




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Transcriptomics and Proteomics Methods for Xenopus Embryos and Tissues

The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements in proteomics methods have enabled quantitative studies to attain better resolution. Here we introduce methods to undertake global analyses of gene expression through RNA and protein quantification in Xenopus embryos and tissues.




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The missing link: monetary policy and the labor share

Bank of England Working Papers by Cristiano Cantore, Filippo Ferroni and Miguel León-Ledesma




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Apple sued over 2016 MacBook Pro 'stage lighting' issue



Apple has been hit with a class-action lawsuit claiming that the company concealed the so-called "stage lighting" issue experienced by some 2016 MacBook Pro owners.




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US commission faults Indian hospital's alleged religious segregation of coronavirus patients

CNA Staff, Apr 17, 2020 / 07:00 pm (CNA).- Reports of an Indian hospital's segregated wards for Hindu and Muslim coronavirus patients drew concern from the U.S. Commission on International Religious Freedom, though Indian authorities strongly disputed the allegation.

"USCIRF is concerned with reports of Hindu and Muslim patients separated into separate hospital wards in Gujarat,” the commission said on Twitter and Facebook April 15. “Such actions only help to further increase ongoing stigmatization of Muslims in India and exacerbate false rumors of Muslims spreading COVID-19.”

The bipartisan U.S. federal government commission linked to a story in the Indian Express newspaper that cites a hospital official and a patient in the city of Ahmedabad in the western coastal Indian state of Gujarat.

India's Ministry for External Affairs opposed the commission, saying it was spreading “misguided reports” and “adding religious color” that distracts from India's efforts to combat the novel coronavirus.

“No segregation is being done in civil hospitals on the basis of religion, as clarified by the Gujarat government,” the ministry said April 15.

The reports concern Ahmedabad Civil Hospital, where there are some 1,200 beds prepared for patients suffering from the novel coronavirus.

Medical Superintendent Dr. Gunvant. H. Rathod described the hospital division to the Indian Express, saying “generally, there are separate wards for male and female patients. But here, we have made separate wards for Hindu and Muslim patients.”

“It is a decision of the government and you can ask them,” he said.

Deputy Chief Minister and Health Minister Nitin Patel said he was not aware of the situation and would make inquiries. Ahmedabad's district magistrate, K.K. Nirala, also was not aware of any decision, the Indian Express reports.

However, the Indian Express cited a hospital patient who said the names of 28 men in a ward were called out, and they were moved to another ward.

“While we were not told why we were being shifted, all the names that were called out belonged to one community. We spoke to one staff member in our ward today and he said this had been done for ‘the comfort of both communities’,” the patient said.

The Gujarat Health and Family Welfare Department said the reports were “absolutely baseless.” Rather, it said, patients are treated based on symptoms and severity and “according to treating doctors' recommendations.

As of Wednesday, new known cases of coronavirus in Gujarat rose by 127 to 766, with 88 cases in Ahmedabad. The death toll there totals 33, the Times of India reports.

The Indian newspaper The Week reported that the commission had previously criticized India's Citizenship Amendment Act, which became effective in January 2020.

In December 2019 the commission expressed concern about the legislation, which enshrined a pathway to citizenship for immigrants but specifically excluded Muslims. The commission recommended U.S. sanctions on India as a possible response.

The U.S. Commission on Religious Freedom reviews alleged religious freedom violations and makes policy recommendations to the U.S. president, Secretary of State, and Congress.

The commission’s 2019 report said that religious freedom conditions in India “continued a downward trend” in 2018. It said India’s “history of religious freedom has come under attack in recent years with the growth of exclusionary extremist narratives—including, at times, the government’s allowance and encouragement of mob violence against religious minorities—that have facilitated an egregious and ongoing campaign of violence, intimidation, and harassment against non-Hindu and lower-caste Hindu minorities. Both public and private actors have engaged in this campaign.”

Mob violence against Christians by Hindus has been particularly acute.

In August 2019, six suspected members of a radical Hindu group were arrested after dozens of Catholics were attacked on a Marian pilgrimage from Karnataka to the Basilica of Our Lady of Good Health in Velankanni, a coastal town in south east India.

In September, around 500 armed Hindu extremists attacked a Jesuit mission in the Archdiocese of Ranchi. Armed with sticks, chains, iron bars, knives, and pistols, the mob beat tribal students including two who were seriously injured, and also seriously damaged the school’s facilities.

Archbishop Leo Cornelio of Bhopal has said numerous mob lynchings of Christians have occurred in which the victims are accused of eating beef or otherwise harming cattle, which are considered sacred in Hinduism.

Karnataka state suffered a wave of anti-Christian violence in 2008, when Hindu extremist groups led attacks on churches, schools and homes of Christians and physically beat hundreds of people. A 2011 independent report on the violence, known as the Saldhana Report, charged that attacks were pre-planned and backed by the state’s highest government authorities.

 



  • Asia - Pacific

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Cardinal Pell 'surprised' by Royal Commission findings

CNA Staff, May 7, 2020 / 11:00 am (CNA).- Cardinal George Pell has expressed his “surprise” at newly released findings of an Australian investigation, which concluded that the cardinal was aware of sexual abuse by clerics in the 1970s and 80s, and failed to act.

In 2017, Australia’s Royal Commission released a report on sexual abuse of minors in the country, the result of a five-year enquiry into the behavior and responsibility of institutions including the Church. Sections of the report relating to Cardinal Pell were redacted until the conclusion of criminal legal proceedings against the cardinal. 

The redacted portions were released May 6.

In the newly available material, the commission found that Pell knew about the abusive activities of two priests during his own years as a priest, and that he failed to act to stop them. 

On Thursday, Pell said through a spokesperson that the commission’s conclusions about him were “not supported by evidence.”

Pell gave evidence to the commission in 2016 via video link from Rome. During his testimony, he denied failing to act against known sexual abusers in the clergy. Pell specifically denied that while he was a priest in Ballarat in the 1970s and 80s, he had any awareness of the actions of then-Father Gerald Ridsdale, a serial abuser from the same diocese.

The Royal Commission concluded that, as a member of Bishop Ronald Mulkearns’ college of priest consulters in the diocese, Pell would have been made aware of allegations of abuse against Ridsdale during discussions about the priest’s transfers between assignments in 1977 and 1982.

But Pell told the commission that he and the other consulters had been deceived by Mulkearns and were unaware of Ridsdale’s crimes until years later.

“The Consultors who gave evidence on the meetings in 1977 and 1982 either said they did not learn of Ridsdale’s offending against children until much later or they had no recollection of what was discussed. None said they were made aware of Ridsdale’s offending at these meetings,” Pell said in a statement released through a spokesperson late Wednesday evening.

In a 2017 statement, Pell said “I would never have condoned or participated in a decision to transfer Ridsdale in the knowledge that he had abused children, and I did not do so.” 

The commission rejected Pell’s testimony, and found that it “ought to have been obvious” why Ridsdale was being transferred from one assignment to another.

“We are satisfied Bishop Mulkearns gave reasons for it being necessary to move Ridsdale. We are satisfied that he referred to homosexuality at the meeting, in the context of giving reasons for Ridsdale’s move,” the report found. “However, we are not satisfied that Bishop Mulkearns left the explanation there, as Cardinal Pell said there would have been a discussion."

“We do not accept that Bishop Mulkearns lied to his consultors.”

The commission did not delineate specific proofs for its conclusion.

The commission also said that Pell would have known about allegations of abuse made against Fr. Peter Searson, who was active as a Melbourne priest during Pell’s time as an auxiliary bishop in the Melbourne archdiocese.

In 1989, Pell held a meeting with representatives from the parish and school in Doveton, where Searson was assigned. During that meeting a number of complaints were made against Searson but, according to Pell, sexual misconduct with children was not raised, and Searson’s removal was not requested.

Following Pell’s installation as Archbishop of Melbourne in 1996, Pell placed Searson on administrative leave and removed him from parish ministry in 1997. Searson died in 2009 and was never charged by police.

A spokesman for Victoria Police, which brought charges against Pell leading to his imprisonment for more than a year before the High Court freed him last month, told the Guardian that the newly released sections of the report would be studied and police would “undertake an assessment of those findings.”

“At this time it would not be appropriate to comment further about any possible action,” The spokesman said.

Current Archbishop of Melbourne Peter Comensoli released his own statement in response to the new material from the commission, in which he repeated his previous apologies “for the failure of the Catholic Archdiocese of Melbourne to responsibly care for and protect our young people and vulnerable adults.”

“Child safety and care is not a project with an end date”, Comensoli said, but a project that “requires life-long vigilance.”

In December 2018, Pell was convicted of five counts of sexual abuse, but was acquitted by the Australian High Court last monthl. Following that decision, the redacted portions of the commission’s findings were released.



  • Asia - Pacific

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Pakistan minorities commission excludes Ahmadi religious group

CNA Staff, May 9, 2020 / 06:01 am (CNA).- Pakistan’s government has declined to include the Ahmadi religious group in its National Commission for Minorities, drawing attention to the group whose Muslim self-identification is rejected by many Muslims.

In a note seen by Reuters, Pakistan’s Ministry of Religious Affairs said Ahmadis should not be included in the commission “given the religious and historical sensitivity of the issue.” Pakistan’s constitution does not recognize the Ahmadis as Muslim.

However, Ahmadis consider themselves part of Islam. The movement was founded in 1889 in British-ruled India. They consider their founder Mirza Ghulam Ahmad a “subordinate prophet.” Other Muslims see this as a violation of the tenet that Muhammad was the last prophet.

There are about 500,000 Ahmadis in Pakistan and up to 20 million adherents worldwide. Some observers estimate the Ahmadi population in Pakistan is higher, but persecution encourages Ahmadis to hide their identity.

Pakistan’s religious freedom record has been a matter of international concern.

The 2020 report of the U.S. Commission on International Religious Freedom has said Ahmadis continue to face “severe persecution from authorities as well as societal harassment due to their beliefs.”

Both government authorities and mobs target their places of worship. In October 2019, the report said, police in Punjab partially demolished a 70-year-old Ahmadiyya mosque.

Pakistan’s National Commission for Minorities gives some status, voice, and protections to minorities in a country where over 90% of people identify as Muslim.

A Hindu has been nominated to chair the minorities commission, whose members include representatives of Christian, Kalash, Sikh, and Zoroastrian communities. Government officials and the head of Pakistan’s Council of Islamic Ideology also have commission seats.

State Minister for Parliamentary Affairs Ali Muhammad Khan, a vocal opponent of including the Ahmadis on the commission, has referred to them as agents of chaos.

“If they want to avail constitutional rights they must accept the constitution first,” he told Reuters. “The Pakistani constitution considers them non-Muslims.”

Usman Ahmad, an Ahmadi representative, told Reuters it is a “complete myth” that they did not accept the constitution. He added that many people disagree with parts of the constitution but still have rights under it.   

He said his community is used to exclusion and has never accepted classification as non-Muslim.

“We’ve never joined such commissions that require us to accept our non-Muslim status,” he said.

Minister of Information Shibli Faraz has said the rights of all people were fully respected in the handling of the commission.

“Every country has the sovereign right to make judgments according to its ground realities,” he told Reuters.

Khan, the Minister for Parliamentary Affairs, had posted to Twitter, then deleted, a comment “There is only one punishment for insulting the Prophet - chopping off the head.” He said he believed in “legal procedures and court proceedings” for those accused of blasphemy. Twitter told him to delete the post, Reuters reports.

Pakistan’s blasphemy laws impose strict punishment on those who desecrate the Quran or who defame or insult Muhammad. Although the government has never executed a person under the blasphemy laws, accusations alone have inspired mob and vigilante violence.

The laws, introduced in the 1980s, are reportedly used to settle scores or to persecute religious minorities. While non-Muslims constitute only 3 percent of the Pakistani population, 14 percent of blasphemy cases have been levied against them.

Many of those accused of blasphemy are murdered, and advocates of changing the law are also targeted by violence.

The Governor of Punjab Salman Taseer was one such critic of the law who was assassinated in January 2011.

Just months later, in March 2011, Shahbaz Bhatti, the first Federal Minister For Minorities Affairs and the only Christian in Pakistan’s cabinet, was assassinated by extremists who characterized him as a blasphemer. Bhatti had criticized the law and defended Asia Bibi, a Catholic woman sentenced to death by hanging in 2010 for blasphemy.

Bibi spent nine years on death row, but left Pakistan for Canada in 2019 at the age of 53 after her death sentence was overturned in October 2018.

The verdict and her subsequent release from prison sparked protests from Islamic hardliners who support strong blasphemy laws.

In Punjab last year, a mob attacked a Christian community after a mosque broadcast over loudspeaker a claim that the Christians had insulted Islam. In another incident in Karachi, false blasphemy accusations against four Christian women prompted mob violence that forced nearly 200 Christian families to flee their homes, the U.S. Commission on International Religious Freedom said.

The situation in Pakistan has attention from some prominent Catholics.

In a Jan. 21, 2020 letter written on behalf of Philadelphia’s Pakistani Catholic community, then-Archbishop of Philadelphia Charles J. Chaput encouraged Pakistan’s Prime Minister Imran Khan to shape a culture of religious freedom

The U.S. Commission on International Religious Freedom’s latest annual report said religious freedom conditions in Pakistan continued to deteriorate last year, citing “The systematic enforcement of blasphemy and anti-Ahmadiyya laws, and authorities’ failure to address forced conversions of religious minorities—including Hindus, Christians, and Sikhs—to Islam.”

The bipartisan federal commission advises the U.S. government on policy. Its report recommended that the U.S. government name Pakistan a country of particular concern for “systematic, ongoing, and egregious violations of religious freedom.”

In December 2018, for the first time, the U.S. State Department designated Pakistan a “Country of Particular Concern.” The designation, which can trigger sanctions under U.S. law, had been recommended by the U.S. Commission for International Religious Freedom in 2017 and 2018.

The latest commission report recommended that Pakistan be re-designated a “Country of Particular Concern,” given “systematic, ongoing, and egregious violations of religious freedom.”



  • Asia - Pacific

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‘I want to be a missionary’

OM friend and volunteer Eddie Ramamonjiarivelo, from Madagascar, is a teacher and businessman with a heart for God’s kingdom.




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Missions is for everyone

An outreach to the north of Madagascar was a new experience not only for those being reached, but for the participants and church as well.




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Media in missions

“Before Media Trek I thought: media--cool hobby, but not necessarily missional,” admitted Kotie-Alet from South Africa.




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A mission trip for the whole family

Ministry opportunities in Hungary open up the mission experience for families with younger children.




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Missing key leads to opportunity

A short-termer engages people in spiritual conversation while on tour of Israel.




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Mission trip taught her dependence on God

Marcela (Argentina) experienced the power of God working through her while on a mission trip in Israel.




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Planting churches with a missions mindset

OMer MacDonald shares how a church in rural Malawi started and has started reaching out.




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A US Pastor's Life Transformed Through Short Term Missions!

Read about how a short term missions trip to a Muslim country changed a US pastor's life! Click to read more!




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Mission Trips for the Whole Family

Getting the whole family involved in a short term missions trip is an unforgettable experience!




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Irish commission: Catholic school discriminated against atheist student

CNA Staff, May 4, 2020 / 05:01 pm (CNA).- The Republic of Ireland’s Workplace Relations Commission has decided that an atheist child was discriminated against by his Catholic school when students were rewarded for attending a religious ceremony.

The commission, an independent, quasi-judicial forum, ruled that the Yellow Furze National School in County Meath had discriminated against an atheist student.

Early in the 2019 school year, the students had been promised a homework pass if they took part in the choir during a First Communion ceremony

The boy’s mother complained, but the school defended its policy.

"Any student, regardless of his/her religion in our school who opted not to participate in this extracurricular event was not 'rewarded,'" the school said, according to the Irish Post last year.

The school added that children of any religion were able to participate in the choir, and that the claim of discrimination was thus “wholly unfounded.”

The commission said the school “does not appreciate this action had an adverse effect on students who are not of a Catholic faith,” the Irish Times reported.

His mother said that "on that day my son was the only child in the class who was not participating. He was also the only non-Catholic child in the class." She added that “he came out of school crying.”

“We are atheist and this is not a choice that is open to him,” she said.

The Irish Post reported in 2019 that the boy was one of two pupils in his class of 33 to receive homework instead of attending the choir ceremony.

According to the commission the boy’s parents were “deeply hurt and upset” by the school.

“We felt that the school had disregarded the fact that we have a different set of beliefs,” the mother told RTE News. “We felt that our child had been singled out and punished for not being a Catholic,” and she added that she hoped the ruling would “change things for children here who are not Catholic".

The mother has since enrolled her son in a different school.

The commission ordered the school to pay €5,000 and demanded the school review its policies so it complies with the Equal Status Acts. The school will also have to post a memo of its compliance in a noticeable location within the school.

The mother told RTE News she will return the €5,000 to the school, “because it will be our friends and our neighbours who will be funding it, through school fundraising. We have been vindicated, but we feel that it would be wrong to accept this money.”

Catholic schools in Ireland make up 90% of all primary schools in the country, the Irish Times reported. The ruling is likely to affect how other schools promote and organize religious events.