sm Those supporting terrorism will meet fate of Afzal Guru: Amit Shah By www.thehindu.com Published On :: Thu, 26 Sep 2024 15:25:45 +0530 The Union Home Minister said, “Even generations after Rahul (Gandhi) would not be able to restore it (Article 370). Elections are being held here for the first time without Article 370 and a separate flag” Full Article Jammu and Kashmir Assembly
sm ‘Dynamite’ Daniel Dubois smashes his way into the heavyweight world title scene By www.thehindu.com Published On :: Sat, 05 Oct 2024 00:22:12 +0530 After destroying fan favourite Anthony Joshua’s redemption arc with a brutal hammering, the IBF champion’s future looks bright. He could await the winner of the Usyk-Fury fight, where the WBA, WBO and WBC belts are on the line, for an opportunity to become the undisputed champion Full Article Other Sports
sm ISKCON organises 'chariot parade' in Houston; draws criticism By www.thehindu.com Published On :: Mon, 11 Nov 2024 11:46:10 +0530 Puri Govardhan Peeth spokesperson said the event was a "conspiracy against our religion" Full Article World
sm Israel FM Smotrich seeks annexation of West Bank during Trump presidency By www.thehindu.com Published On :: Tue, 12 Nov 2024 11:25:03 +0530 The remarks came as Saudi Arabia held an extraordinary summit of Arab and Islamic leaders in Riyadh. Full Article World
sm Drones to be deployed to check sand smuggling By www.thehindu.com Published On :: Sun, 03 Nov 2024 20:17:40 +0530 The unmanned aerial vehicles will be used to check illegal sand mining, smuggling, stock-keeping, and selling sand on the black market, says Police Commissioner Full Article Andhra Pradesh
sm Chief Minister wants to create one entrepreneur in every family in A.P., says MSME Minister By www.thehindu.com Published On :: Tue, 05 Nov 2024 22:21:13 +0530 The government plans to set up incubation centres and is formulating a virtual workplace policy with incentives for people who set up workplaces, says Kondapalli Srinivas Full Article Andhra Pradesh
sm Tourism Minister releases book on Andhra Pradesh at Rajamahendravaram By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:09:47 +0530 Full Article Andhra Pradesh
sm Nellore Collector urges SIDBI to boost local MSMEs By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:54:30 +0530 The SIDBI shall provide financial assistance to all MSMEs under its various schemes, identify better marketing strategies and increase their opportunities, says O. Anand Full Article Andhra Pradesh
sm The application of a self-designed microfluidic lung chip in the assessment of different inhalable aerosols By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2111-2119DOI: 10.1039/D4AY00017J, PaperZezhi Li, Xiang Li, Boyang Feng, Junwei Zhao, Kejian Liu, Fuwei Xie, Jianping XieMicrofluidic-based assessment platforms have recently attracted considerable attention and have been widely used for evaluating in vitro toxic effects.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm A portable fluorescence detection device based on a smartphone employing carbon nanodots for Mn2+ sensing By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2101-2110DOI: 10.1039/D4AY00027G, PaperPijika Mool-am-kha, Samuch Phetduang, Kessarin Ngamdee, Chayada Surawanitkun, Xiang-Kui Ren, Wittaya NgeontaeA low-cost, portable, and low-energy consumption fluorescence reader-based smartphone device employing carbon nanodots for detection of Mn2+.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2077-2084DOI: 10.1039/D4AY00041B, PaperWenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan YangHere, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Aptamer aided plasmonic nano-urchin for reporter free surface-enhanced Raman spectroscopy analysis of cortisol By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00401A, PaperChengyu Li, Jing Hu, Nan Hu, Jianjun Zhao, Qianwen Li, Yanhui Han, Yanxiong Liu, Xufang Hu, Liyan Zheng, Qiu-E CaoCortisol is a vital glucocorticoid hormone reflecting stress levels and related disease processes. We present an aptamer functionalized plasmonic nano-urchin (α-FeOOH@Au-aptamer) aided cortisol capturing and Surface-enhanced Raman spectroscopy (SERS) analysis...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00236A, PaperGasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel DuerkopA new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm LAMP-based hydrogen ion selective electrochemical sensor for highly sensitive detection of Mycoplasma pneumoniae By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00341A, PaperHuiqing Wang, Yang Li, Lin Tian, Xinyi Li, Qian Gao, Yaru Liu, Cuiping Ma, Qing Wang, Chao ShiAn urgent need for a concise and rapid detection method for Mycoplasma pneumoniae is required due to its severe impact on human’s health. To meet such a need, this study...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D3AY02075D, PaperNatpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat PasomsubAnalytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2330-2339DOI: 10.1039/D3AY02271D, PaperHong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan LiuFatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Fe3+-induced luminescence quenching in carbon dots – mechanism unveiled By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2349-2358DOI: 10.1039/D3AY02202A, PaperVarsha Raveendran P.T., Anjali C., Renuka Neeroli KizhakayilLuminescence quenching in carbon dots with an increase in Fe3+ concentration and the quantitative variation in luminescence intensity with added ferric ions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00487F, PaperJinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang LiuSmall extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm The not-so-smart use of mobiles By www.thehindubusinessline.com Published On :: Wed, 07 Aug 2013 17:27:58 +0530 Full Article R Dinakaran
sm Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3444-3459DOI: 10.1039/D4MD00318G, Research ArticleAnuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar MaitiNiloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3460-3468DOI: 10.1039/D4MD00405A, Research ArticleXiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli BiSchematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3485-3494DOI: 10.1039/D4MD00246F, Research ArticleShouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng XuA novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024) By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3371-3394DOI: 10.1039/D4MD00384E, Review ArticleDebasis Das, Lingzhi Xie, Jian HongProspects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3616-3624DOI: 10.1039/D4MD00306C, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. SheldrakeCyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00673A, Review ArticleJuhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong JunPotential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Design, synthesis and mechanistic insights into triclosan derived dimers as potential anti-plasmodials By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00494A, Research Article Shekhar, Shefali Chowdhary, Joel Mosnier, Isabelle Fonta, Bruno Pradines, Vipan KumarIn pursuit of novel anti-plasmodial agents, a library of triclosan-based dimers both with and without a 1H-1,2,3 triazole core were designed, synthesized and evaluated in order to achieve a multitargeted approach.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00619D, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marina Perieteanu, Tayner Rodriguez Garzon, Leah M. C. McGee, Abedawn I. Khalaf, Colin J. Suckling, Rebecca Beveridge, Vicky M. Avery, Fraser J. Scott25 S-MGBs, including those bearing an amidine tail group, were investigated for their antiplasmodial, in vitro activity against 3D7 and Dd2 strains of P. falciparum. Several potent, and selective, hit compounds were identified.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Novel quinoxaline-derived derivatives: design, synthesis, bioactive evaluation, SARs and preliminary antibacterial mechanism By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00670D, Research ArticleYuting Liu, Pengju Yang, Yunyun Zhou, Zhiwen ZhouIn the current study, we have designed and prepared a series of quinoxaline-based compounds, which were derived from o-phenylenediamine. Among which, compounds 5m-p displayed good to moderate antibacterial activity with...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00553H, Research ArticleStefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro CosconatiNon-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sm Agro-tourism push needs industry-specific policies, say farmers By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:37:41 +0530 Full Article Tiruchirapalli
sm Small-scale handloom park to come up at Sengunthapuram By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:09:38 +0530 Ministers R. Gandhi and S.S. Sivashankar inspect the 13,205 sq. ft. site belonging to the Tamil Nadu Cotton Corporation at Sengunthapuram Full Article Tiruchirapalli
sm Site identified for small-scale handloom park in Karur By www.thehindu.com Published On :: Sat, 09 Nov 2024 19:30:54 +0530 Full Article Tiruchirapalli
sm 595: MedTalk Show, Plagiarism and Code Grifting, and How We’re Testing Code By shoptalkshow.com Published On :: Mon, 11 Dec 2023 09:03:30 +0000 Blood pressure, stress, and COVID highlight the MedTalk Show portion of this episode, a new "Did You Know" segment about dev tools in Chrome, 4 hour video on plagiarism and code grifters, typography, breaking out of CSS Grid, the oldest things Chris and Dave worked on, and what the testing process is like at Luro or CodePen. Full Article All Episodes css grid plagirism Testing Typography
sm Design water-smart cities By www.thehindu.com Published On :: Fri, 16 Jan 2015 17:08:47 +0530 We need an army of people who will ensure the protection of water bodies, and who will strive to create a water-literate community. Full Article Property Plus
sm Smart water solution By www.thehindu.com Published On :: Fri, 01 May 2015 16:18:06 +0530 A bunch of Chennai students are making Paani Genie, a 90-litre water container that can be rolled along. Full Article Design
sm Cold plunges, hot saunas, smoothies, and fasting By www.thehindubusinessline.com Published On :: Sun, 06 Oct 2024 21:49:00 +0530 Fitness regimen on the go Full Article Pulse
sm How radio waves can power smart cities By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 21:40:29 +0530 Practically omnipresent, thanks to human activity, radio frequency is the new area of focus for energy harvesting technology Full Article Science and Technology
sm CEA plans 613 GW RE transmission capacity By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 18:36:40 +0530 Higher generation of renewable energy challenges grid stability Full Article Clean Tech
sm Craft beer: Growth in small batches By www.thehindubusinessline.com Published On :: Sun, 10 Nov 2024 20:47:55 +0530 A favourite with millennials and GenZ for their artisanal products, microbreweries are set to expand, backed by VCs Full Article Emerging Entrepreneurs
sm Delhi riots case: HC dismisses plea by Khalid Saifi against attempt to murder charge By www.thehindu.com Published On :: Tue, 05 Nov 2024 13:00:21 +0530 Mr. Saifi submitted that once the offences under the Arms Act were dropped against him and neither any weapon was recovered nor the alleged gunshot was attributed to him, the charge of attempt to murder could not be framed Full Article Delhi
sm Delhi HC dismisses plea by Khalid Saifi against attempt to murder charge By www.thehindu.com Published On :: Wed, 06 Nov 2024 01:19:07 +0530 Full Article Delhi
sm Delhi’s air quality remains ‘very poor’, layer of smog over city for ninth day post-Diwali By www.thehindu.com Published On :: Sat, 09 Nov 2024 10:26:29 +0530 Delhi’s air quality reaches severe levels, blamed on stubble-burning, Diwali fireworks, and low wind speed Full Article Delhi
sm Cashing out of a business, smartly By www.thehindubusinessline.com Published On :: Sun, 09 May 2021 20:04:10 +0530 The book draws upon diverse experiences of entrepreneurs to highlight the need for an exit strategy Full Article Books
sm Need for climate-smart agriculture in India By www.thehindu.com Published On :: Sat, 25 Nov 2023 00:59:26 +0530 Climate-smart agriculture has the potential to assure food security, empower farmers, and protect our delicate ecosystems Full Article Lead
sm How can small-scale farmers benefit from trees on farms? By www.thehindu.com Published On :: Thu, 18 Apr 2024 05:30:00 +0530 The adoption of agroforestry at scale in India by smallholders is currently stymied by ecological and socio-economic factors Full Article Environment
sm KAU, Asia’s largest cocoa germplasm repository, ready to release six more clones By www.thehindu.com Published On :: Thu, 18 Apr 2024 19:04:14 +0530 Full Article Kerala
sm Mangrove restoration in T.N. makes a small but steady progress By www.thehindu.com Published On :: Tue, 06 Aug 2024 22:24:48 +0530 The Tamil Nadu Forest Department and non-governmental organisations are working to restore mangroves at various sites of the Ennore-Pulicat wetlands. In the meantime, the National Centre for Coastal Research has identified land available for restoration in Cuddalore, Tiruvarur, Thanjavur, Pudukkottai, Ramanathapuram, and Thoothukudi Full Article Tamil Nadu
sm ICAR team makes tool small enough to edit plant genomes By www.thehindu.com Published On :: Thu, 22 Aug 2024 05:30:00 +0530 In a genome-editing landscape low on options for plants, the new tool has scientists enthused about its applications in agriculture Full Article Science
sm Centre talks to States on new mechanism to gather crop data By www.thehindu.com Published On :: Thu, 22 Aug 2024 21:39:32 +0530 The national conference discusses the Digital General Crop Estimation Survey to enhance agricultural statistics accuracy and transparency for policy formulation and planning Full Article India