Sidewalk Labs officially pulled out of Toronto after years of controversy, hacker bribed a Roblox worker to reveal user account data, Telus’ revenue falls by nearly 20 per cent year over year.   Sidewalk Labs pulls the plug on smart city project The tug-of-war for Toronto’s infamous Sidewalk Labs’ smart city project ended yesterday when…

The meatpacking industry has slowed down due to the coronavirus outbreaks at the plants. Meatpackers warn that it could lead to meat shortages and stores limiting purchases.

Tina Fey returned to Saturday Night Live to lament the quarantine and dream about Governor Cuomo’s alleged nipple ring. The SNL alum and 30 Rock creator joined Michael Che on her old post on Weekend Update, where she famously appeared alongside Jimmy Fallon and Amy Poehler between 2000 and 2006. She joked about Zoom backgrounds, […]

The crisis has also unearthed new opportunities for investors eyeing distressed hospitality and retail assets.

The post Southeast Asia’s realty market braces for short-term instability appeared first on DealStreetAsia.

Jacqueline Fernandez has stumbled upon life-altering realisations amid the ongoing lockdown due to the coronavirus pandemic. The actress says she has realised that life is too short, and it is important to make the most of the time we have in our hands.

"Honestly, the biggest lesson has been that when it comes to humankind we are pretty irrelevant, which means that we are extremely blessed to be on this planet because the planet would go on with us or without us. So, we have to be grateful and give back. That's the realisation -- we take Earth for granted," Jacqueline said, while reflecting upon how the lockdown has been a learning period for her.

"(Another lesson is that) life is short. We need to be doing things that we enjoy doing and love. We should be spending time with the people we love because you are here one day and gone the next. We really have to make the most out of life. It is such a lesson. These are the two main things I have realised during this period," added the actress, who is spending her lockdown with superstar Salman Khan and others at his farmhouse in Panvel.

Amid the shutdown, she is making the most of her time by enjoying moments like horse-riding, basking in the sun and reading a book -- evident in her recent Instagram posts.

On the work front, she was recently seen in "Mrs. Serial Killer", which released on Netflix on May 1. "Mrs. Serial Killer" is directed by Shirish Kunder and produced by his filmmaker wife Farah Khan. The thriller is about a wife, whose husband has been framed and imprisoned for serial murders. She needs to perform a murder exactly like the serial killer, to prove that her husband is innocent.

The film hinges on the question -- how far would you go for love.

Asked how far she would go for the people she loves, Jacqueline said: "I always think that when it comes to people you love, you kind of throw logic out of the window. But I am someone who is all about making sure that you are doing the right thing.

"It has to be the right thing. I always try to put that into perspective. If I feel a right thing is being done, then I will probably go to whatever extent I need to. I would never harm anyone though for love. I would do anything for love except harm anyone," said the actress, who won Miss Sri Lanka beauty pageant in 2006.

She made her debut in the Indian film industry with 2009 film "Aladin" opposite actor Riteish Deshmukh. The film turned out to be a dud at the box office, but Jacqueline got noticed and went on to do films like "Housefull 2", "Murder 2", "Kick", "Brothers", "Dishoom" and "Judwaa 2". "Mrs. Serial Killer" also stars Manoj Bajpayee and Mohit Raina.

Recalling the experience of working on the thriller, Jacqueline said: "It was great. They were so patient, kind and very supportive. There was a beautiful sense of unity and teamwork, and you learn so much from working with such amazing actors. It was really a beautiful experience."

Now, she is looking forward to the release of the song "Tere bina" with Salman, which they have shot amid the lockdown in the farm premises itself.

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The holiday season may be a good time to eat, drink and have a ball but over indulgence can peel several years off one'

Current carbon prices are falling short of the levels needed to reduce greenhouse gas emissions driving climate change, but even moderate price increases could have a significant impact, according to new OECD research.

Current carbon prices are falling short of the levels needed to reduce greenhouse gas emissions driving climate change, but even moderate price increases could have a significant impact, according to new OECD research.

Canada has experienced solid economic growth since the global crisis, allowing it to reverse recession-induced job losses and put federal public finances on a sound footing, says the OECD. Growth is expected to accelerate from 2.5% this year to 2.7% in 2015.

Discussion on how technology helps measuring skills shortages in real time

At the turn of this century, two different models of higher education programmes prevailed in the world.

Deputy director of China's National Health Commission Li Bin said that reforms are underway to improve the country's disease prevention and control mechanisms.

Major League Baseball appears tentatively set to approve a plan that would call for an 80-game regular season beginning in early July. MLB Commissioner Rob Manfred is seen above.

Speaking to The Mirror at the NME Awards on Thursday,  the singer, 27, criticised the ceremony for making the women feel like a 'subplot' or 'warm-up act' for their male counterparts.

The model, 34, put on a very leggy display in a perilously short black mini dress with daring thigh-high slits on the side.

Amid the worldwide toilet paper shortage, Khloé Kardashian plastered her older sister Kourtney's home with the highly sought-after paper good. 

Cenk Tosun has cut short his loan to Crystal Palace and returned to Everton amid concerns he is facing six months out with an injury after rupturing knee ligaments during training.

The new National Curriculum Framework has put the child firmly at the centre of its proposals. But critics point out that it has overlooked many problems, such as the lack of infrastructure, inadequate teacher training, and continuing social biases. Some provisions have also been attacked as obscurantist. Deepa A reports.

Archives, Room Use Only - TK5115.M37 1904

Archives, Room Use Only - TK6015.R64 1904

Archives, Room Use Only - HE7669.P55 1914

Archives, Room Use Only - JX238.A7 M33 1871

Archives, Room Use Only - TK6540.S86 1950

Archives, Room Use Only - TK140.S5 E55 1953

Archives, Room Use Only - HE7669.P55 1925

Archives, Room Use Only - TK5115.S45 1934

VACB squads to conduct checks across State

Online short story contest winner announced

The COVID-19 outbreak exposed “shortcomings” in China’s public healthcare system, a top health official admitted on Saturday, saying that reforms are

Minister for Dairy Development K.T. Rajenthra Bhalaji, on Saturday, said there was no short supply of Aavin milk in any part of Chennai or Tamil Nadu.

The title tetra­nuclear copper complex, [Cu4Cl6O(C6H9N3O3)4] or [Cu4Cl6O­(MET)4] [MET is 1-(2-hy­droxy­eth­yl)-2-methyl-5-nitro-1H-imidazole or metronidazole], contains a tetra­hedral arrangement of copper(II) ions. Each copper atom is also linked to the other three copper atoms in the tetra­hedron via bridging chloride ions. A fifth coordination position on each metal atom is occupied by a nitro­gen atom of the monodentate MET ligand. The result is a distorted CuCl3NO trigonal–bipyramidal coordination polyhedron with the axial positions occupied by oxygen and nitro­gen atoms. The extended structure displays O—H⋯O hydrogen bonding, as well as unusual short O⋯N inter­actions [2.775 (4) Å] between the nitro groups of adjacent clusters that are oriented perpendicular to each other. The scattering contribution of disordered water and methanol solvent mol­ecules was removed using the SQUEEZE procedure [Spek (2015). Acta Cryst. C71, 9–16] in PLATON [Spek (2009). Acta Cryst. D65, 148–155].

The title compound [systematic name: (1R*, 8S)-2-acetamidoocta­hydro­pyrrol­izin-4-ium chloride–N-[(1R, 8S)-hexa­hydro-1H-pyrrolizin-2-yl)acetamide (1/1)], 2(C9H16N2O)·HCl or C9H17N2O+·Cl−·C9H16N2O, arose as an unexpected product when 1-exo-acetamido­pyrrolizidine (AcAP; C9H16N2O) was dissolved in CHCl3. Within the AcAP pyrrolizidine group, the unsubstituted five-membered ring is disordered over two orientations in a 0.897 (5):0.103 (5) ratio. Two AcAP mol­ecules related by a crystallographic twofold axis link to H+ and Cl− ions lying on the rotation axis, thereby forming N—H⋯N and N—H⋯Cl⋯H—N hydrogen bonds. The first of these has an unusually short N⋯N separation of 2.616 (2) Å: refinement of different models against the present data set could not distinguish between a symmetrical hydrogen bond (H atom lying on the twofold axis and equidistant from the N atoms) or static or dynamic disorder models (i.e. N—H⋯N + N⋯H—N). Computational studies suggest that the disorder model is slightly more stable, but the energy difference is very small.

Smithsonian herpetologist George Zug answers a few questions about skinks....

The post Speaking of skinks: short limbed, long tailed & prehistoric appeared first on Smithsonian Insider.

It is a simple solution to a wildlife water shortage. During the annual dry season [November through April] in a protected forest in eastern Cambodia, […]

The post This simple trick helped fix a wildlife water shortage in Cambodia appeared first on Smithsonian Insider.

Aparna Sherlekar, Gayatri Mundhe, Prachi Richa, Bipasha Dey, Swati Sharma, and Richa Rikhy

Branched actin networks driven by Arp2/3 collaborate with actomyosin filaments in processes such as cell migration. The syncytial Drosophila blastoderm embryo also shows expansion of apical caps by Arp2/3 driven actin polymerization in interphase and buckling at contact edges by MyosinII to form furrows in metaphase. Here we study the role of Syndapin (Synd), an F-BAR domain containing protein in apical cap remodelling prior to furrow extension. synd depletion showed larger apical caps. STED super-resolution and TIRF microscopy showed long apical actin protrusions in caps in interphase and short protrusions in metaphase in control embryos. synd depletion led to sustained long protrusions even in metaphase. Loss of Arp2/3 function in synd mutants partly reverted defects in apical cap expansion and protrusion remodelling. MyosinII levels were decreased in synd mutants and MyosinII mutant embryos have been previously reported to have expanded caps. We propose that Syndapin function limits branching activity during cap expansion and affects MyosinII distribution in order to shift actin remodeling from apical cap expansion to favor lateral furrow extension.

In the battle against invasive species, giant commercial ships are on the front lines. But even when they follow the rules, one of their best […]

The post Battle against invasive marine species comes up short as global shipping surges appeared first on Smithsonian Insider.

The post Short video featuring the fieldwork of Smithsonian scientists created in 2000, posted by the Smithsonian Archives appeared first on Smithsonian Insider.

An image from a teaser for Marvel Comics' 2015 "Civil War," part of crossover "Secret Wars." Could Spidey appear in the new Captain America: Civil War film now that Marvel and Sony have worked out a deal?; Credit: Marvel

Spider-Man is coming home to join the rest of the Marvel movie family (um, except for the Fantastic Four and the X-Men) in upcoming films under a new deal struck between Sony, the home for Spider-Man movies, and Disney's Marvel Studios, home of Iron Man and the Avengers

It's been a bumpy road for Spidey for almost a decade, but now he's set to be part of the largely critically and financially successful Marvel Cinematic Universe films. He's already made history, and he could make more history soon. 

Here's a brief history of cinematic Spider-Man, looking ahead to his new adventures with Marvel's large and growing stable of movie superheroes.

Coming out of the superhero dark ages

Spider-Man was one of the catalysts for the current superhero movie boom. Superhero films were seen as potentially dead following the bomb of "Batman & Robin" with George Clooney, a critical failure and a mixed bag commercially.

Marvel dipped its toes in superhero movies with 1998's "Blade," which was a big hit, followed by 2000's "X-Men," but they both tried to distance themselves from their comic book source material (and the Joel Schumacher Batman movies) by putting their heroes in black leather and grounding them as much as possible in real-life aesthetics.

Sony's first "Spider-Man" movie came out in 2002 and showed that there was still room for an optimistic comic book take. The Sam Raimi-directed film also had a huge cultural impact as one of the first big summer movies following 9/11 — an early teaser that showed Spidey trapping bad guys between the two towers had to be pulled following the disaster.

Spider-Man 9/11 trailer

The movie ended up pulling in almost $822 million at the box office, including almost $404 million domestically, helmed by genre director Raimi, who had previously been best known for the horror-comedy "Evil Dead" films.

Spider-Man trailer

Tobey Maguire surprised as the star, pulling off the nerdy, earnest Peter Parker while also being believable enough as an action star in the Spider-Man suit. Maguire starred alongside Kirsten Dunst as love interest Mary Jane and Willem Dafoe as the villainous Green Goblin, and the film included the not-yet-a-superstar James Franco as Harry Osborn and now-Oscar-nominated J.K. Simmons as Daily Bugle publisher J. Jonah Jameson.

A sequel, 2004's "Spider-Man 2," continued the success of the first, with only a slight dip in overall box office while proving that the first film's success wasn't just a flash in the pan, that there was room for a relatively bright superhero in a dark time.

Spider-Man 2 trailer

Maguire almost ducked out of filming during negotiations, complaining of back pains following injuries while filming "Seabiscuit," and Jake Gyllenhaal almost stepped into the role — but Maguire recovered and held onto his spot. The escapist entertainment of superhero movies was starting to take hold in a growing way, but the superhero train was about to come off the rails for a few years.

The twilight of Tobey Maguire

As "Spider-Man 2" was hitting theaters, 2004 also brought "The Punisher," "Blade: Trinity" and "Catwoman," none of which showed superheroes as particularly promising movie saviors.

Marvel turned out more superhero movies that weren't loved by critics, including "Elektra," "Fantastic Four" and "X-Men: The Last Stand," though the latter two still did well at the box office (all were released by 20th Century Fox). DC Comics made the critical and commercial hit "Batman Begins" in 2005, but stumbled in 2006 with the underperforming "Superman Returns."

In 2007, "Spider-Man 3" dropped, and while it did great at the box office — it was the series' most popular film worldwide, though it dipped domestically — it was slammed by fans and critics. They took that Spider-Man optimism and tried making him emo, while overstuffing the bad guys — going from one villain in the previous films and upping it to three — and turning the campy dialogue up to 11.

Spider-Man 3 trailer

Trying to be 'Amazing' in a new superhero era

While Spidey stumbled, the next year Marvel released its first film from its own studio, the groundbreaking "Iron Man." It showed that you could make a franchise from a hero who was big in the comics but didn't have the same mainstream recognition.

It revitalized Robert Downey Jr.'s career and put Marvel Studios on the map, with a post-credits sequence laying the seeds for completely tying the films together in a way that hadn't been done on this scale ever before.

While Marvel started to crank up their self-produced film, Spider-Man lay dormant. Eventually, it was decided to reboot the character with Andrew Garfield taking over the role in 2012's "The Amazing Spider-Man." It scored the lowest domestic take of the series, while still excelling overseas.

Amazing Spider-Man 2 trailer 1

Sony quickly followed up with a sequel, while announcing their own plans to ape Marvel and try to create their own cinematic universe.

Amazing Spider-Man 2 villains trailer

The second "Amazing Spider-Man" movie set up other potential villains, and holding off the payoff of what exactly happened to Peter Parker's parents as Marvel tried to stretch Spider-Man into a female-led film, one focused on the villains, a movie led by Spidey character Venom and more.

Amazing Spider-Man first 10 minutes

The sequel showed diminishing returns, though, and plans for further sequels and spinoffs began to seem up in the air.

Hacked

In the midst of the Sony hack, documents revealed that Sony and Marvel had been negotiating over Marvel using Spider-Man in its own films — despite Sony having the rights to the character in perpetuity as long as they kept producing films, a deal worked out before Marvel had the resources and the belief in their own filmmaking capabilities. Still, the documents also showed that the talks had fallen apart, and hopes for Spider-Man appearing with Iron Man, Captain America, Thor and the rest of his Marvel friends appeared dim.

Then, Monday, Marvel shocked everyone by announcing that Spider-Man was coming home and would be part of the Marvel Cinematic Universe after all. There had been reports that they'd wanted Spider-Man for the third Captain America film, and with that film set for 2016, that may still happen. They also pushed back four of their "Phase Three" movies to make room in 2017 for a new "Spider-Man" movie, with reports indicating that the movie will feature a new actor taking over and Andrew Garfield getting pushed aside.

Spider-Man comes home

Andrew Garfield will likely go down in comics movie history as the right guy at the wrong time. He was a likable lead with a strong supporting cast, but Marvel looks ready to turn the page. Those on the Marvel side have previously indicated they'd avoid doing another origin story, so we'll probably skip seeing Uncle Ben killed to inspire Peter Parker once again.

"The new relationship follows a decade of speculation among fans about whether Spider-Man – who has always been an integral and important part of the larger Marvel Universe in the comic books – could become part of the Marvel Universe on the big screen," Marvel said in the announcement of the new deal.

Fans online have been largely ecstatic over the announcement of Marvel getting control of the character. Reports indicate that Sony still gets final say over Spider-Man, but that they're letting Marvel take the creative lead. Marvel also announced the possibility that other Marvel characters could appear in future Spider-Man films.

While Sony's Amy Pascal stepped down as the motion picture head of Sony following the hacking scandal and its associated public embarrassments, she's staying on as a producer — including co-producing the next Spider-Man film with Marvel creative film leader Kevin Feige.

Some fans have also asked for an even bigger step away from the traditional Spider-Man by introducing Miles Morales, the popular half-black/half-hispanic Spider-Man from an alternate universe in the comics, but the official Marvel press release does mention Peter Parker, and Marvel executives have previously taken a strong stance against moving away from Parker as the secret identity.

Still, as Badass Digest's Devin Faraci notes, the executive who'd taken the strongest stance against Miles Morales — Avi Arad — isn't mentioned in the press release about the new film, so maybe Marvel will surprise fans once again. Also, relations have apparently been icier between Marvel and Fox, with fans speculating that Marvel is trying to ice out the X-Men and the Fantastic Four from their comics — but if the companies could work out a deal to use those heroes in a Marvel Cinematic Universe film, it could prove to be an even bigger surprise.

The new Spider-Man film is set for July 28, 2017, and he may appear in another Marvel film sooner.

This content is from Southern California Public Radio. View the original story at SCPR.org.

President Trump speaks at the White House Friday. He is replacing an official who issued a report that found testing delays and equipment shortages at hospitals.; Credit: Jim Watson/AFP via Getty Images

President Trump is moving to replace the Department of Health and Human Services watchdog whose office found severe shortages of medical supplies in hospitals as COVID-19 cases surged.

In a Friday night announcement, the White House named Jason Weida as its nominee to take the permanent inspector general post currently occupied by Christi Grimm, who's been in that role in an acting capacity since January.

A longtime staffer with Health and Human Services, Grimm was leading the inspector general's office in April when it issued a report chronicling testing delays — up to seven days in some cases — as well as severe shortages of supplies in hospitals amid the COVID-19 pandemic.

"Hospitals reported that they were unable to keep up with COVID-19 testing demands because they lacked complete kits and/or the individual components and supplies needed to complete tests," the survey of 323 hospitals found. "When patient stays were extended while awaiting test results, this strained bed availability, personal protective equipment (PPE) supplies, and staffing."

The report also recalled how one hospital had even resorted to making its own disinfectant.

Trump reacted to the report by calling its findings "wrong," asking to know the name of the inspector general and suggesting the report was politically motivated. He later took to Twitter to castigate Grimm and the report even further.

"Why didn't the I.G., who spent 8 years with the Obama Administration (Did she Report on the failed H1N1 Swine Flu debacle where 17,000 people died?), want to talk to the Admirals, Generals, V.P. & others in charge, before doing her report. Another Fake Dossier!" Trump tweeted in early April.

Grimm is a career official, not a political appointee, and began serving in the Office of the Inspector General in 1999.

The nomination of Weida — currently an assistant U.S. attorney — marks the latest replacement of a high-level watchdog by the president. A month ago, he fired the inspector general who raised concerns that eventually led to his impeachment. Days later, he removed the inspector general charged with overseeing the government's coronavirus response bill.

Sen. Patty Murray, ranking Democrat on the Health, Education, Labor and Pensions Committee, said that Trump's nominee "must not get through the Senate without ironclad commitments" to continue the agency's current investigations without political interference.

"We all know the President hasn't told people the truth about this virus or his Administration's response, and late last night, he moved to silence an independent government official who did," Murray said in a statement released on Saturday. "Anyone who demands less will be complicit in the President's clear pattern of retaliation against those who tell the truth."

Health and Human Services did not comment to NPR on Grimm's future role, but said in statement that the agency had been preparing "to assist a new Inspector General appointee over a year ago, when the previous presidentially-appointed and senate-confirmed Inspector General first announced his intention to retire from government service. We will continue to work conscientiously to support a smooth leadership transition."

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: Patrick Semansky/AP

The U.S. Supreme Court has once again punted on the question of gun rights, throwing out as moot a challenge to New York City's strict gun regulations on transporting licensed guns outside the home.

New York City, in the name of public safety, has very strict gun regulations. It allows people to have a permit for guns in their homes, but those regulations originally barred people from transporting their guns anywhere except shooting ranges within the city. The New York State Rifle & Pistol Association challenged the regulation as a violation of the Second Amendment right to bear arms and lost in the lower courts.

But, after the Supreme Court agreed to review the case, New York state and New York City changed their laws to allow gun owners to transport their guns outside the city to shooting ranges, to competitions, and to second homes. That gave the challengers exactly what they asked for in their lawsuit, and so on Monday, the court, by a 6-to-3 vote, dismissed the case as moot--in short, it no longer presented a live controversy.

The unsigned opinion was joined by Chief Justice John Roberts, the court's four liberals, and Trump appointee Brett Kavanaugh.

But Kavanaugh wrote separately to stress that while he agreed with the majority on procedural grounds, he agreed with the dissenters--Justices Samuel Alito, Clarence Thomas, and Neil Gorsuch--on one key issue.

Those three said that the lower courts were using the wrong test to evaluate gun laws, a test that is far too deferential to gun regulators. The dissenters mainly argued however, that the court essentially had been gamed on the mootness question, and that the justices should have decided the case, and decided it for the gun owners.

Gun-safety advocates breathed a sigh of relief that there was no decision adverse to gun regulations. But they worry that gains they are making in some state legislatures may be taken away by a conservative court majority.

"The reality is that the gun-safety movement is winning in state houses and at the ballot box, so the NRA is turning to the court to try to change the tide," says Eric Tirschwell, managing mirector of Everytown for Gun Safety.

Monday's decision was the first in a major gun case in 10 years, the first since a landmark set of decisions in 2008 and 2010. In those cases, a sharply divided court ruled that the Second Amendment right to bear arms is an individual right, not a right associated with the militia, as the court had previously implied. Those decisions marked a huge victory for the NRA and other gun-rights organizations.

In the decade following that decision, however, the court did not agree to hear any of the dozens of challenges to gun restrictions in cases appealed to the court. In part because the composition of the court made outcomes uncertain.

The previous big gun cases were decided by 5-to-4 votes, with Justice Anthony Kennedy casting the fifth and decisive vote. Kennedy, according to court sources, insisted, as the price of his vote, on adding limiting language that likely would have resulted in some, maybe even most, gun restrictions being upheld. With neither side of the court sure how Kennedy would vote on most regulations, neither the pro-gun, nor the pro-gun-control side wanted to risk an adverse ruling.

That changed when Kennedy retired in 2018 to be replaced by Justice Kavanaugh, who has a much more gun-friendly record than Kennedy did.

Nothing Kavanaugh said in his concurring opinion Monday would dissuade anyone from thinking he has changed his mind.

Bottom line here is that when it comes to gun control, there look to be four pretty solid votes against a lot of the measures enacted in recent years after mass shootings. Specifically, laws that bar carrying weapons in public places, and bans on assault weapons and large ammo magazines. All these, plus so called red-flag laws and other measures could be in jeopardy.

The question is where Chief Justice Roberts will be on these and other gun-control questions. To date, he has never been much of a supporter of gun-control laws, but he hasn't been an outspoken opponent, either. All we really know is that he was part of the 2008 and 2010 majority that for the first time declared that the Second Amendment is an individual right, not, as the court had previously implied, a collective right that was attached to the colonial militia.

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: Alyson Hurt/NPR

To safely phase out social distancing measures, the U.S. needs more diagnostic testing for the coronavirus, experts say. But how much more?

The Trump administration said on April 27 the U.S. will soon have enough capacity to conduct double the current amount of testing for active infections. The country has done nearly 248,000 tests daily on average in the last seven days, according to the nonprofit Covid Tracking Project. Doubling that would mean doing around 496,000 a day.

Will that be enough? What benchmark should states try to hit?

One prominent research group, Harvard's Global Health Institute, proposes that the U.S. should be doing more than 900,000 tests per day as a country. This projection, released Thursday, is a big jump from its earlier projection of testing need, which was between 500,000 and 600,000 daily.

Harvard's testing estimate increased, says Ashish Jha, director of the Global Health Institute, because the latest modeling shows that the outbreak in the U.S. is worse than projected earlier.

"Just in the last few weeks, all of the models have converged on many more people getting infected and many more people [dying]," he says.

But each state's specific need for testing varies depending on the size of its outbreak, explains Jha. The bigger the outbreak, the more testing is needed.

Thursday Jha's group at Harvard published a simulation that estimates the amount of testing needed in each state by May 15. In the graphic below, we compare these estimates with the average numbers of daily tests states are currently doing. (Jump to graphic)

Two ways to assess whether testing is adequate

To make their state-by-state estimates, the Harvard Global Health Institute group started from a model of future case counts. They calculated how much testing would be needed for a state to test all infected people and any close contacts they may have exposed the virus. (The simulation estimates testing 10 contacts on average.)

"Testing is outbreak control 101, because what testing lets you do is figure out who's infected and who's not," Jha says. "And that lets you separate out the infected people from the non infected people and bring the disease under control."

This approach is how communities can prevent outbreaks from flaring up. First, test all symptomatic people, then reach out to their close contacts and test them, and finally ask those who are infected or exposed to isolate themselves.

Our chart also shows another testing benchmark for each state: the ratio of tests conducted that come back positive. Communities that see around 10% or fewer positives among their test results are probably testing enough, the World Health Organization advises. If the rate is higher, they're likely missing a lot of active infections.

What is apparent from the data we present below is that many states are far from both the Harvard estimates and the 10% positive benchmark.

Just nine states are near or have exceeded the testing minimums estimated by Harvard; they are mostly larger, less populous states: Alaska, Hawaii, Montana, North Dakota, Oregon, Tennessee, Utah, West Virginia and Wyoming.

Several states with large outbreaks — New York, Massachusetts and Connecticut among others — are very far from the minimum testing target. Some states that are already relaxing their social-distancing restrictions, such as Georgia, Texas and Colorado, are far from the target too.

Jha offers several caveats about his group's estimates.

Estimates are directional not literal

Researchers at the Global Health Initiative at Harvard considered three different models of the U.S. coronavirus outbreak as a starting point for their testing estimates. They found that while there was significant variation in the projections of outbreak sizes, all the models tend to point in the same direction, i.e. if one model showed that a state needed significantly more testing, the others generally did too.

The model they used to create these estimates is the Youyang Gu COVID-19 Forecasts, which they say has tracked closely with what's actually happened on the ground. Still the researchers caution, these numbers are not meant to be taken literally but as a guide.

If social distancing is relaxed, testing needs may grow

The Harvard testing estimates are built on a model that assumes that states continue social distancing through May 15. And about half of states have already started lifting some of those.

Jha says, that without the right measures in place to contain spread, easing up could quickly lead to new cases.

"The moment you relax, the number of cases will start climbing. And therefore, the number of tests you need to keep your society, your state from having large outbreaks will also start climbing," warns Jha.

Testing alone is not enough

A community can't base the decision that it's safe to open up on testing data alone. States should also see a consistent decline in the number of cases, of two weeks at least, according to White House guidance. If their cases are instead increasing, they should assume the number of tests they need will increase too.

And Jha warns, testing is step one, but it won't contain an outbreak by itself. It needs to be part of "a much broader set of strategies and plans the states need to have in place" when they begin to reopen.

In fact, his group's model is built on the assumption that states are doing contact tracing and have plans to support isolation for infected or exposed people.

"I don't want anybody to just look at the number and say, we meet it and we're good to go," he says. "What this really is, is testing capacity in the context of having a really effective workforce of contact tracers."

The targets are floors not goals

States that have reached the estimated target should think of that as a starting point.

"We've always built these as the floor, the bare minimum," Jha says. More testing would be even better, allowing states to more rapidly tamp down case surges.

In fact, other experts have proposed the U.S. do even more testing. Paul Romer, a professor of economics at New York University proposed in a recent white paper that if the U.S. tested every resident, every two weeks, isolating those who test positive, it could stop the pandemic in its tracks.

Jha warns that without sufficient testing, and the infrastructure in place to trace and isolate contacts, there's a real risk that states — even those with few cases now — will see new large outbreaks. "I think what people have to remember is that the virus isn't gone. The disease isn't gone. And it's going to be with us for a while," he says.

Daniel Wood contributed to this report.

This content is from Southern California Public Radio. View the original story at SCPR.org.