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Student jailed for attempted rape in east London after CCTV operator spotted crime by chance

A student who was caught on CCTV trying to sexually assault a woman at an east London bus stop has been jailed for four years.




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From “Our Rape Blog”: Shooting the Moon

[caption id="" align="alignnone" width="324"] From ‘The Red Tree’ by Shaun Tan[/caption] Have you ever played Hearts? It’s a card game. For our purposes, the important part is this: every card in the heart suit is worth points, and (just like golf) players want to avoid those points. I played a lot of Hearts as a [...]




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Kate Garraway says husband Derek Draper is 'still very ill' in intensive care as she speaks of 'torture' over 'horrific virus'

"I am very aware that I'm not the only one going through this torture" Read our live coronavirus updates HERE




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Kate Garraway says husband Derek Draper is still in a 'deeply critical condition' in hospital

Draper is one of the thousands of people in the UK to have been diagnosed with coronavirus




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Kate Garraway shares update on husband Derek Draper's health as he remains in intensive care

"Where there is life, there is hope," Garraway wrote in her emotional post




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Kate Garraway praises 'amazing' NHS as she shares update on husband Derek Draper's 'battle' with coronavirus

Coronavirus: the symptoms




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Ben Shephard shares update on Kate Garraway's husband Derek Draper as presenter turns 53

Garraway's husband remains in hospital with coronavirus




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Kate Garraway says celebrating birthday while husband Derek Draper is in hospital was 'tough'

Draper has been in hospital with Covid-19 since late March




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Former NIH chief favored as Trump’s ‘therapeutics czar’

Zerhouni is thought to be the favorite, said two people, and one person said that Azar personally prefers Zerhouni for the role.




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Alleged Sydney rape victim of Chinese actor Yunxiang Gao 'begged' to be freed, court hears

A jury hears how a woman who was allegedly gang raped by prominent Chinese actor Yunxiang Gao, and a producer, in a Sydney hotel room begged the men to let her go.




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Strippers ‘drugged, assaulted and raped’

AN EXOTIC dancer claims she was abused and “drugged into near unconsciousness” for not going along with a club’s scheme. WARNING: Graphic.




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Daw committed to stand trial over alleged rape

North Melbourne footballer Majak Daw has been committed to stand trial over the alleged rape of a teenage girl in 2007.




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Lyra Therapeutics IPO Raises $56M for Tests of Tech for Runny Noses

Lyra Therapeutics, a biotech company developing a new way to treat your persistently runny nose, has raised $56 million in its public markets debut. Late Thursday, Lyra offered 3.5 million shares priced at $16 apiece, which was the high end of its projected $14 to $16 price range. Those shares are expected to begin trading […]




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PTC Therapeutics to Acquire Censa Pharma for Mid-Stage Rare Disease Drug

PTC Therapeutics has reached an agreement to acquire Censa Pharmaceuticals and its lead asset, an experimental metabolic disorder therapy that is now being prepared for a pivotal study. The deal, announced after the market close Wednesday, will bring South Plainfield, NJ-based PTC (NASDAQ: PTCT) another compound for its pipeline of rare disease drugs. Wellesley, MA-based […]




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Disarm Therapeutics hires Dr Alvin Shih as new President and CEO

Massachusetts-based biotech Disarm Therapeutics has hired Dr Alvin Shih as their new President and CEO.

The Cambridge, Mass.-based firm has set itself the task of creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central drive of neurological disease.

Dr Shih brings to the role a range of experiences. Having graduated with a biology degree from Vanderbilt University in 1996, Shih joined management consultancy McKinsey where he worked as a business analyst for two years.

read more




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Seres Therapeutics appoints Dr Lisa von Moltke as new Chief Medical Officer

Dr Lisa von Moltke has left Aklermes and has joined Seres Therapeutics as its new Chief Medical Officer.

Chief Executive Officer at Seres, Eric Shaff, said Seres will benefit from von Moltke’s “extensive experience directing successful development programs, leading clinical teams, and interacting with regulatory agencies across multiple areas of medicine.”

read more




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Novartis acquires digital therapeutics specialist Amblyotech

The pharmaceutical firm has purchased the company, which specializes in advancing treatments and diagnostics for ocular disorders.



  • Markets & Regulations

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Express Scripts + Prime Therapeutics: Our Four Takeaways From This Market Changing Deal (rerun)

This week, I’m rerunning some popular posts while I prepare for this Friday’s video webinar: Industry Update and COVID-19 Impact: PBMs & Payers.

I suspect this deal will remain profitable for the participating companies even as COVID-19 alters the US. prescription payer mix. Click here to see the original post and comments from January 2020. National market shares for the largest PBMs in 2019 appears as Exhibit 88 of our 2020 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers.

P.S. Sorry that today's meme is one day too late for Star Wars day.



Just before the holidays, Cigna’s Express Scripts business announced a market-changing deal with Prime Therapeutics. Click here to read the press release.

There's been very little written about this transaction, though it has potentially major implications. Below, I share my thoughts on the following topics arising from the deal:
  • Implications for manufacturers and pharmacies
  • The role of the secretive Ascent Health Services
  • What this all means for Walgreens
  • Why the Federal Trade Commission won’t challenge the deal
A few weeks ago, I explained why integrated insurer / PBM / specialty pharmacy / provider organizations are poised to restructure U.S. drug channels. The Express Scripts / Prime deal signals that the channel will continue its amazing pace of reinvention.

The scale, scope, and interconnectedness of today’s market participants make the system increasingly resistant to massive disruption from either external players like Amazon or a government takeover. Like it or not, the channel will continue to gain power and extract profit. Read on and see if you agree.
Read more »
        




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Oligonucleotide Therapeutics and Delivery Conference 2020

16 - 17 September 2020, London, UK.
Oligonucleotide therapeutics - the emerging medicine class - are harnessing the therapeutic benefit of targeting genetic material via antisense, mRNA, RNAi, saRNA and siRNA. Their market growth: CAGR of 13.7% projected to reach USD 8.2 billion by 2024 is driven by their potential to provide more efficacious and less toxic alternatives to small molecules.




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PTC Therapeutics to acquire Censa Pharmaceutical

In another strategic M&A deal announced so far this month, PTC Therapeutics has entered into an agreement…



  • Biotechnology/Censa Pharmaceuticals/Companies
  • mergers and acquisitions/Metabolics/PTC Therapeutics/Rare diseases/sepiapterin/USA

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FBI Arrests Jordanian Citizen for Attempting to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi, 19, has been arrested and charged in a federal criminal complaint with attempting to use a weapon of mass destruction.



  • OPA Press Releases

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Man Admits Attempting to Use a Weapon of Mass Destruction to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi pleaded guilty today before U.S. District Judge Barbara M. G. Lynn to a felony offense related to his attempted bombing of a downtown Dallas skyscraper in September 2009.



  • OPA Press Releases

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Man Sentenced to 24 Years in Prison for Attempting to Use a Weapon of Mass Destruction to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi was sentenced today by U.S. District Court Judge Barbara M. G. Lynn to 24 years in prison for his attempted bombing of a downtown Dallas skyscraper in September 2009.



  • OPA Press Releases

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Justice Department Releases Proposed Rule in Accordance with the Prison Rape Elimination Act

The Justice Department today released a proposed rule that aims to prevent and respond to sexual abuse in incarceration settings, in accordance with the Prison Rape Elimination Act.



  • OPA Press Releases

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Attorney General Eric Holder Announces Revisions to the Uniform Crime Report’s Definition of Rape

Attorney General Eric Holder today announced revisions to the Uniform Crime Report’s (UCR) definition of rape, which will lead to a more comprehensive statistical reporting of rape nationwide. The new definition is more inclusive, better reflects state criminal codes and focuses on the various forms of sexual penetration understood to be rape.



  • OPA Press Releases

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Justice Department Releases Final Rule to Prevent, Detect and Respond to Prison Rape

The Justice Department today released a final rule to prevent, detect and respond to sexual abuse in confinement facilities, in accordance with the Prison Rape Elimination Act of 2003 (PREA).



  • OPA Press Releases

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Justice Department Releases Updated Protocol to Improve Standards for Responding to Rape and Sexual Assault

Attorney General Eric Holder today announced a revised version of the National Protocol for Sexual Assault Medical Forensic Examinations (SAFE Protocol, 2d.) The SAFE Protocol is a voluntary best practices guide to conducting sexual assault medical forensic examinations protocols.



  • OPA Press Releases

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Department of Justice Announces 48 States and Territories Have Committed to Ending Prison Rape

Deputy Attorney General James M. Cole and Principal Deputy Assistant Attorney General for Justice Programs Mary Lou Leary announced today that the vast majority of U.S. states and territories have informed the Department of Justice that they intend to take steps to reduce sexual assaults in prisons, in accordance with federal law.



  • OPA Press Releases

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Deputy Attorney General James Cole Speaks at Press Conference Updating States’ Efforts to Comply with Prison Rape Elimination Act

"These [PREA] standards, like the law mandating them, are intended to address a serious public safety, public health and human rights problem – the incidence of sexual violence in our nation’s confinement facilities."




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Principal Deputy Assistant Attorney General Mary Lou Leary Speaks at Press Conference Updating States’ Efforts to Comply with Prison Rape Elimination Act

"It’s clear that our nation will no longer tolerate sexual violence in our prisons, jails and juvenile detention centers – and that’s something we should all be proud of."




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Axsome Therapeutics (AXSM) Advances To Cross $100-Mark

Axsome Therapeutics Inc.'s (AXSM) phase II/III trial of investigational drug AXS-05 in Alzheimer's disease agitation has met the primary endpoint.




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Relmada Therapeutics (RLMD): Sending The Right Signals?

Shares of Relmada Therapeutics Inc. (RLMD) have gained 19 percent so far this year and trade around $37.




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The Promise Of Precision Neuroscience And Launch Of Arkuda Therapeutics

Neuroscience has had a tough run of news lately. With Amgen deprioritizing neuro this year, Pfizer doing the same last year, and others like BMS, GSK, and AZ cutting back on CNS a few years earlier, it would seem dark

The post The Promise Of Precision Neuroscience And Launch Of Arkuda Therapeutics appeared first on LifeSciVC.




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Thinking Boldly: Alkermes Acquires Rodin Therapeutics

Today Alkermes announced its acquisition of Rodin Therapeutics, a leader in the field of synaptic dysfunction and neuronal epigenetics. Alkermes extensive experience in CNS diseases made them an ideal partner for Rodin, and this acquisition helps expand Alkermes’ efforts into

The post Thinking Boldly: Alkermes Acquires Rodin Therapeutics appeared first on LifeSciVC.




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PTC Therapeutics nabs 'phase 3 ready' biotech Censa for just $10M upfront plus stock

PTC Therapeutics is adding to its rare disease pipeline with a midstage biotech buyout with a low upfront payment tied in with stock and biobucks.




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After Alexion buyout, ex-Achillion nephrology lead jumps ship to Gemini Therapeutics

Just a few months after Alexion snapped up complement inhibitor biotech Achillion, Gemini Therapeutics has nabbed one of its key R&D execs as its new chief medical officer.




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Orchard Therapeutics cuts 25% of staffers, rethinks pipeline, closes California site

Tough times at Orchard Therapeutics as it swings the ax across staffers and facilities, phases in new pipeline advances and reduces interest in others.




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Therapeutic efficacy of Pudilan Xiaoyan Oral Liquid (PDL) for COVID-19 in vitro and in vivo




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Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma




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The nuclear oncoprotein Fra-1: a transcription factor knocking on therapeutic applications’ door




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PARP inhibitors as a new therapeutic option in metastatic prostate cancer: a systematic review




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RNAi against therapeutic targets with short interfering ribonucleic neutrals (siRNNs)

siRNNs could enable RNAi knockdown of therapeutic targets in a broader range of cells and tissue types than siRNA.




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Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor

Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives.




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Nuclear receptor crosstalk — defining the mechanisms for therapeutic innovation




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Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke




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Parkinson disease and the immune system — associations, mechanisms and therapeutics




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Surgeon’s protection during ophthalmic surgery in the Covid-19 era: a novel fitted drape for ophthalmic operating microscopes




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Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo




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The skyscraper and the shack: What slum policy should not be about


After decades of neglect, Latin American governments are increasingly focusing on urban slums. What often spurs their policy interventions is a desire to counter violent criminality leaking out from the poor marginalized slums controlled by gangs into the city centers the better-off residents want to keep safe. But tackling the socioeconomic dynamics of slums -- the trap of poverty, discrimination, lack of public goods and social services, and rule by nonstate actors -- is not only complex, but also costly. Governments, elites, and middle classes tend not to want to spend resources on slums. Effective policies have to be sustained for decades, and political will and tax revenues for such complex state-building are frequently scarce.

Focusing on a discreet intervention – providing low-cost housing – becomes tempting. Rarely is it sufficient. The condition of the buildings alone is not what makes a slum a slum. Moving residents from slums to better low-cost housing has encountered systematic challenges not just in Latin America, but also in other places where it has been tried, such as Kenya. Instead, policies need to focus on broader community dynamics, including public safety, legal job creation with sufficient income, human capital development, and robust connectivity of slums to economically-thriving areas, something residents of the latter often don’t want.

Paradoxically, real estate dynamics can have pernicious effects. If broader pacification does take hold and public safety in slums increases, some slum areas can become desirable real estate with vast development possibilities. Developers may well seek to buy the land by offering “better” low-cost housing to slum residents to get them to move. Since many slum residents do not have title to their residences, forced displacement also occurs, albeit under the cloak of being nice to the poor.

Instead of being limited to the provision of alternative residences, policies to address slums need to be about inclusion, economic growth, safety, and connectivity of slums with the thriving city parts, and accountability of city-governance authorities.

This commentary was originally published by the Inter-American Dialogue’s Latin America Advisor. 

Publication: Inter-American Dialogue
Image Source: © Eddie Keogh / Reuters
     
 
 




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Vincent Callebaut Designs "Bionic Arch"- A Green Skyscraper For Taiwan

When Jerry wrote about Vincent Callebaut's proposed vertical farm for New York City, he called it a Locavore Wet Dream; I called it one of the silliest, most overwrought jump-the-shark vertical farm ideas ever