Laurent Robert wooed the Geordie public between 2001 and 2005 - now he wants his son Thomas to experience the same

Sunderland's move to write off £20.5m loan as an exceptional operating expense will have a big impact, according to a football finance expert

PROSPECT 100 has launched a global online music talent competition to help singers, producers, instrumentalists, and other musicians 21 and under, work towards their artistic goals during the … more

The wait is over. After MLB Pipeline unveiled its Top 10 Position lists over the past two weeks, it's time to dive into the Top 100 Prospects, the best of the best.

Hong Kong has been embroiled in increasingly violent social unrest since June, 2019. We examined the associated population mental health burden, risk factors, and health-care needs.

Chet Culver really should have known better.

Iowa’s former Democratic governor wrote a letter to current Republican Gov. Kim Reynolds decrying her administration’s declaration that workers who refuse to return to jobs amid COVID-19 fears would be denied unemployment benefits. He was among many who questioned whether Reynolds’ policy is even lawful, considering that unemployment rules allow Iowans to claim benefits for unsafe, intolerable or detrimental working conditions.

“Any such ill-conceived scheme that deprives them of choice and forces those hardworking, yet vulnerable, employees to report to unsafe workplace environments, while the positive incidences of COVID-19 infection are on the rise, is not merely penny-wise and pound-foolish — it is just plain wrong,” Culver argued.

But Culver should have known any overture for the rights of workers during the pandemic would fall on deaf ears. We learned Tuesday that more than 1,600 workers at four meatpacking plants tested positive for the virus. Reynolds continues insisting companies such as Tyson, with more than 1,300 cases at three facilities, are doing all they can to protect workers. In one Tyson facility at Perry, 58 percent of its employees contracted the virus.

Culver lost in 2010 to the Branstad-Reynolds ticket, a team that would go on to gut collective bargaining for public employees and make it far more difficult for injured workers to get compensation, among other greatest hits composed by its big business allies.

And Culver was bounced from office after issuing bonded debt to help Iowa communities, including Cedar Rapids, recover from natural disasters of 2008. Republicans dubbed him “Big Debt Chet” and decried his mismanagement of a crisis.

Strong management, apparently, is Reynolds’ decision to partially reopen 77 counties even as COVID-19 case numbers grow and deaths mount, and before ramped up testing and modeling provide critical information on the scope of the virus.

On Monday Reynolds received a lofty “A” grade from FreedomWorks and the Committee to Unleash Prosperity. Reynolds appeared on a conference call sponsored by the groups to talk about her strategy for reopening Iowa.

FreedomWorks and the Committee to Unleash Prosperity are conservative groups playing a key role in organizing “liberation” protests in Wisconsin, Oklahoma and elsewhere. FreedomWorks, with roots in the Tea Party movement, has been mobilizing local protesters and organizing events, according to The New York Times. It’s also conducting tracking polls in swing congressional districts and sharing data with presidential advisers and congressional staff.

“This isn’t political, and it shouldn’t be for anybody,” Reynolds told reporters this week when asked about her virus response.

FreedomWorks is among 24 groups who sent a letter to the president in April urging him to waive the Renewable Fuel Standard for the rest of the year due to pandemic concerns, potentially freeing Iowa farmers from more of their already scarce income.

So step aside Big Debt Chet. We’re unleashing prosperity. Even if workers get trampled.

(319) 398-8262; todd.dorman@thegazette.com

At this point in our locked-down lives, it’s entirely possible many of us have exhausted our Netflix queue, completed every puzzle in our houses and perfected our sourdough loaves. OK, probably not.…

Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C4-C8 polyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.

A procedure and system for determining and placing spinal implants or prostheses includes measuring a change in position of vertebrae at an affected level of a patient's spine from a first position where the patient reports greatest pain at the affected level, to a second position where the patient reports least pain at the affected level. Spinal implants or prostheses are selected so as to urge the affected level of the spine toward the second position and away from the first position when the implants are placed at the affected level. In one embodiment, an implant device is formed by one or more inflatable balloons that are placed at determined locations inside a disc space at the affected level. When the balloons are inflated, vertebrae above and below the balloons are urged toward the second position and away from the first position at the affected level.

Endoprothesis delivery systems and methods for making an using the same. An example medical endoprosthesis delivery system may include an inner member. An outer member may at least partially surround the inner member. The inner member and the outer member may be configured so that an implantable medical endoprosthesis can be disposed therebetween. A coupling device may be coupled to a portion of the outer member so that, when there is substantially no slack in the coupling device, as the coupling device moves in a proximal direction the portion of the outer member moves in the proximal direction. An adjustable stop may be coupled to the coupling device so that, when there is slack in the coupling device, as the adjustable stop is moved in the proximal direction, the amount of slack in the coupling device can be reduced.

Devices and methods for implantation at a native mitral valve. One embodiment of the device includes a valve support having a first region and a second region, and anchoring member having a longitudinal dimension with a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion transverse to the longitudinal dimension between the first portion and the second portion. The anchoring member and the valve support are configured to move from a low-profile configuration to an expanded configuration in which the first portion of the anchoring member at least partially adapts to the non-circular annulus of the native mitral valve and a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member.

A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has an annulus section with a relatively small cross-section, and an aortic section with a relatively large cross-section. The valve assembly, including a cuff and a plurality of leaflets, is secured to the stent in the annulus section such that the valve assembly can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section is held by the delivery device in a manner that allows for resheathing. The configuration of the prosthetic valve is such that the valve leaflets can fully coapt and the valve can function properly even when the stent and/or valve assembly become distorted upon deployment or use.

The present invention relates to an image-based, patient-specific medical spinal surgery technique and to a spinal prosthesis used in the surgery, and particularly, to an image-based, patient-specific medical spinal surgery technique and to a spinal prosthesis which are intended to solve a problem of damage to a spine caused by installing a spinal prosthesis used in spinal surgery, by introducing an image of a patient to manufacture an insertable spinal prosthesis that is customized for a shape of a spine of an individual patient in a polymer-based material.

The intervertebral disc prosthesis comprises first and second plates (3, 4) designed to be attached on one of the two vertebrae adjacent to the intervertebral disc to be replaced, and a compression pad arranged between the first and second plates. Each plate comprises first attaching means including two attaching portions (14a, 14b) positioned symmetrically on either side of the anteroposterior median plane of said plate, second attaching means including two attaching portions (15a, 15b) positioned symmetrically on either side of a first plane inclined by an angle comprised between 50° and 70° relative to the anteroposterior median plane of said plate, and third attaching means opposite the second attaching means relative to the anteroposterior median plane and including two attaching portions (16a, 16b) positioned symmetrically on either side of a second plane inclined by an angle of approximately 90°, relative to the anteroposterior median plane of said plate.

A modular, adjustable, prosthetic hip/shoulder spacer adapted to being implanted in the hip or shoulder joint; the spacer comprises a frame that supports a rotatable cylinder from which a neck extends with the ball element of the joint attached to its end, and rotating the cylinder reposition the ball in the socket; the stem is connected to the base of the frame and is implanted in the long bone (femur or humerus); the stem may be modified to include a system for delivering medication to the implantation site following surgery. The stem leg and stem base may be modified to form a modular unit to adjust the relation between a center line of the stem leg and a center line of the frame and position of the neck and ball.

The invention comprises a method for treating a prostate to alleviate prostate cancer, benign prostatic hyperplasia (BPH), and other conditions. The method involves inserting a tool to create a small self-sealing puncture site through tissue to gain access to a portion of a prostate, inserting a probe though the puncture site into the prostate, activating the probe to treat the prostate, withdrawing the probe and inspecting a surgical site for a flow of urine or semen to determine whether a sufficient amount of prostate tissue has been treated, and inspecting for hemostasis. The method may also include delivering a luminally protective sheath before inserting any instruments, using a template to guide insertion of the probe, and delivery of tamponading balloons to assist with attainment of hemostasis after the coring procedure.

Methods and devices for ophthalmic tissue closure and fixation of ophthalmic prostheses are provided. In accordance with some embodiments, devices for both grasping and clipping a plurality of ocular tissue and ocular prostheses are provided. Various device embodiments are provided for both malleable clips and delivery of normally closed clips (i.e. shape memory). The device may accommodate a plurality of clips which include, but are not limited to: malleable metals, absorbable, shape memory, drug-eluting, and adhesive dispensing. The clips may be pigmented to match the colors of associated tissue (cornea, iris, conjunctiva, sclera, retina) to serve to camouflage fixation clips for healing duration or permanently. According to one aspect, shallow angle access to anatomy may be provided by specialized angulation of device shaft and closure jaws that are intended to access the eye through a small self-healing cornea incision and/or any ocular tissue.

A prosthetic inserter includes an inserter head having at least first and second bosses, at least one of the bosses movable from a first position to a second position, that couple the inserter to a femoral provisional component via a pair of corresponding apertures, such as drill holes, within the articulating surfaces of a selected one of a series of femoral provisional components. Each provisional component of the series is capable of having different aperture distances measured between a respective pair of apertures. The bosses of the inserter are biased into an engagement position in which the inserter can be secured to a femoral provisional component to eliminate the need for an external engagement force to be supplied to the inserter.

There is provided a moveable power seat slide device assembly comprising a movable seat cushion and seat rail including upper rails secured to the seat cushion and lower rails secured to the body of the golf cart, a motor for driving each movable seat and a current control circuit. The prostate golf cart seat protects the prostate area from continuous bouncing. The seat has two 8 inch stationary end cushions. The center would consist of two 8 inch cushions moving along a rail which allows riders to automatically close the 7 inch seat gap to 3 inches from the stationary end cushion. The center air space between each rider and seat would have a depth 1½ inches.

This invention provides new above knee (AK) and below the knee (BK) prosthetic sockets and implements specific manufacturing processes for the production of prosthetic sockets through the automated, computer controlled bi-axial and tri-axial braiding of sockets, over a mold or mandrel made of carved foam, plaster material or wax that is a replica of the patient's truncated limb, and is created by a Computer Aided Design (CAD) file controlling a Numerically Controlled (CNC) machine tool. This method of manufacture using aerospace fibers such as graphite or Kevlar, and high performance resins, is used to create a socket which is stronger and lighter weight than conventionally manufactured sockets. Braiding also allows incorporation of woven cloth, tapes and other reinforcements into the braiding process for added strength at selected areas. The method dramatically decreases the production time and cost of the prosthetic relative to conventional methods.

Provided herein are methods for the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient. In particular, gene expression levels of GCOM1, MEX3D, TRPM4, ATPAF1, PTRF, GLYATL1, FLNA, OBSCN, STRA13, WHSCl, ARFGAP3, KDM2A, FAM83H, CLDN7, CNOT6, and B3GNT9 are measured. Kits containing means for the measurement of gene expression as described herein and methods for treatment of prostate cancer are also provided.

This disclosure relates to methods, computer products, computer-implemented methods, and systems for predicting the probability or risk of prostate cancer recurrence and tumor aggressiveness in a patient. The method is based, in part, on the patient's risk profile that includes the presence/degree of specific copy number variations and predictive clinical factors. The methods and systems can be used to aid in treatment selection.

Root canal abutment devices and methods which facilitate the adjustment or removal of an oral appliance, e.g., a crown or bridge, from a reconfigurable abutment assembly are described. The adjustable abutment assembly may be secured within a pulp chamber of a pre-existing tooth. The abutment assembly has a projecting abutment portion with one or more shape memory alloy sleeves or plates or elements extending along the abutment. Each of the sleeves has a length with at least one curved or arcuate portion. Energy may be applied to the elements such that the arcuate portion flattens to allow for the oral appliance to be placed thereupon while removal of the energy allows the elements to reconfigure into its curved configuration thereby locking the oral appliance to the abutment. Removal of the oral appliance may be effected by reapplication of energy to the elements.

Custom dental prosthesis or implants each individually designed and manufactured to replace nonfunctional natural teeth positioned in a jawbone of a specific pre-identified patient are provided. An example dental prosthesis/implant includes a dental implant body having a prosthesis interface formed therein to receive an occlusally-facing dental prosthesis component. The prosthesis interface has a custom three-dimensional surface shape positioned and formed to create a form locking fit with respect to the occlusally-facing dental prosthesis component when positioned thereon.

A method to detect prostate cancer comprising contacting a sample of prostate cells from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in prostate tumor tissue, PIN (intra-epithelial neoplasia), histologically benign tissue and benign prostatic hyperplasia (BPH); a method to combine immunofluorescence and FISH (IF-FISH) to facilitate the assessment of chromosomal abnormalities; a set of probes; and a kit comprising the set of probes and instructions for diagnosing prostate cancer in a patient.

TWO HAMPSHIRE based, community football teams will soon be facing off in a charity game analysed by top ex-professionals.

The letter by the prosecutor marked the second time businesses in town were contacted by authorities for being in violation of Gov. Ducey's order.

St. Louis' first black prosecutor, Kim Gardner, has sued the city, its police union and five others for what she calls a racist effort to block her reform agenda. "Gardner was elected in 2016 on a promise to redress the scourge of historical inequality and rebuild trust in the criminal justice system among communities of color," reads the lawsuit filed Monday in federal court. "Unfortunately, entrenched interests in St. Louis ... have mobilized to thwart these efforts through a broad campaign of collusive conduct" to protect the status quo and remove Gardner from office. Jacob Long, a spokesman for Mayor Lyda Krewson, said the city "vehemently denied what it considers to be meritless allegations levied against it" and expected to be "fully vindicated." Jeff Roorda, a police union official named in the suit, called it "the last act of a desperate woman." The suit has its roots in the 2018 prosecution of then-Missouri Gov. Eric Greitens. Gardner hired an outside investigator to look into

Abandoning the case is the latest step in a pattern of dismantling the work of the Russia investigators. A former prosecutor likened it to eating the department from the inside out.

A question I sometimes get asked in my Mailchimp classes is how Mailchimp may be used in the sales funnel. Mailchimp can be used effectively in various parts of the sales funnel and in this video I show how prospects may be differentiated from leads in a Mailchimp Audience. In summary, email marketing is an […]

This article appeared first at ❤ OrganicWeb - Mailchimp training, consulting & integration experts.

Oregon produced the top pick from the Pac-12 in the 2020 NFL Draft and is the heavy favorite to produce the Pac-12’s top pick in the 2021 NFL Draft.

The four players sure seemed thrilled to be playing some tennis with some prize money (amount undisclosed) at stake amid the coronavirus pandemic — even if the court was near the backyard swimming pool at someone’s mansion and there were zero ATP rankings points on the line, zero locker rooms, zero spectators, zero ball kids […]

The lawsuit echoed allegations made by other former employees claiming Mark Roe spoke and acted inappropriately while serving as the county’s top prosecutor from 2009 until his retirement in 2018.

Oregon produced the top pick from the Pac-12 in the 2020 NFL Draft and is the heavy favorite to produce the Pac-12’s top pick in the 2021 NFL Draft.

The four players sure seemed thrilled to be playing some tennis with some prize money (amount undisclosed) at stake amid the coronavirus pandemic — even if the court was near the backyard swimming pool at someone’s mansion and there were zero ATP rankings points on the line, zero locker rooms, zero spectators, zero ball kids […]

Rumor has it that college basketball is in trouble. Google the name Jalen Green and you'll surely be shown a story hinting at NCAA hoops' inevitable decline. Columnist Matt Calkins thinks the college game is going to be just fine.

Oregon produced the top pick from the Pac-12 in the 2020 NFL Draft and is the heavy favorite to produce the Pac-12’s top pick in the 2021 NFL Draft.

Oregon produced the top pick from the Pac-12 in the 2020 NFL Draft and is the heavy favorite to produce the Pac-12’s top pick in the 2021 NFL Draft.

The four players sure seemed thrilled to be playing some tennis with some prize money (amount undisclosed) at stake amid the coronavirus pandemic — even if the court was near the backyard swimming pool at someone’s mansion and there were zero ATP rankings points on the line, zero locker rooms, zero spectators, zero ball kids […]

Police spent months investigating allegations by a 16-year-old girl who said she was sexually assaulted in 2018 by four Eastside Catholic High School football players, but prosecutors said they didn't have enough evidence to prosecute. Lawyers for the players' say they are innocent.

The New Zealand Prime Minister Jacinda Ardern will join the Australian National Cabinet Meeting via video link tomorrow to talk about the way through the COVID-19 pandemic.

Not long ago, Aboriginal people in Cherbourg were ruled by a government-appointed "protector". Now the elders are involved in running the courts.

A man with a disability was strip searched and prosecuted after a false claim he was photographing children at a beachside suburb, leading to calls for an apology from WA Police.

Got a metal detector? This outback town is setting up a prospecting lease for tourists who want to try their hand at landing a gold nugget.

Locals describe it as the "worst drought in living memory" but things are about to get worse in the Queensland town of Stanthorpe with its water supply just weeks from drying up.

The shire's mayor says with more than 500,000 people from the Gold Coast having their beaches closed and all descending on the Tweed, it is a "pretty frightening prospect for our community".

When a former Australian solider saw a video of a colleague who'd lost three limbs in a landmine blast it sparked a new purpose in his life.

Prosecutors argue George Pell's victim was a "witness of truth" as they contend the disgraced Cardinal's child sex abuse convictions are "unimpeachable" and should be upheld.

This specialist nurse teaches thousands of prostate cancer survivors how to revitalise their sex life after diagnosis, but she is the only one of her kind in an area spanning 48,000 square kilometres.