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Officials Probe Deadly Plane Crash

[VOA] The Somali government is promising a thorough investigation into the crash of a Kenyan supply plane Monday that killed six people amid suspicions it may have been shot down.




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Amisom Welcomes the Decision By the Governments of Somalia, Kenya and Ethiopia to Investigate Plane Crash Incident in Bardale

[Dalsan Radio] The African Union Mission in Somalia, AMISOM, expresses its heartfelt condolences to the families of those who perished in the plane crash of 4th May, 2020. The aircraft which left Baidoa, had six people on board and was approaching Bardale, south of Somalia and 300km northwest of the capital Mogadishu when it crashed.




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AU, UN Hail Investigation Into Cargo Plane Crash in Somalia

[Shabelle] The African Union and the UN have welcomed the decision by leaders from Somalia, Kenya, and Ethiopia to investigate Monday's plane crash in southwest Somalia which killed six people on board.




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Thirty cars crash on the D10 close to Březina near Mladá Boleslav

Prague Daily Monitor

The details are still unclear but early Saturday evening a car crash involving multiple vehicles was reported on the D10 close to Březina near Mladá Boleslav. Firefighters reported 27 cars involved. Micheala Fliegerova, the spokesperson for the police reported over 30 participants were involved in the crash.

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IAF MiG-29 jet crashes in Jalandhar

NEW DELHI: A MiG-29 multirole fighter jet of the Indian Air Force crashed during a training mission near Punjab’s Jalandhar Friday. The pilot ejected safely. He was soon taken away in a rescue helicopter, the IAF said in a statement. "The aircraft had developed a technical snag and the...




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IAF MiG-29 jet crashes in Jalandhar

NEW DELHI: A MiG-29 multirole fighter jet of the Indian Air Force crashed during a training mission near Punjab's Jalandhar Friday.The pilot ejected safely. He was soon taken away in a rescue helicopter, the IAF said in a statement."The aircraft had developed a technical snag and the pilot...




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IAF MiG-29 jet crashes in Jalandhar

NEW DELHI: A MiG-29 multirole fighter jet of the Indian Air Force crashed during a training mission near Punjab's Jalandhar Friday.The pilot ejected safely. He was soon taken away in a rescue helicopter, the IAF said in a statement. "The aircraft had developed a technical snag and the pilot...




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Drop in Drunk Driving Crashes May Have Boosted U.S. Economy

Title: Drop in Drunk Driving Crashes May Have Boosted U.S. Economy
Category: Health News
Created: 4/30/2015 12:00:00 AM
Last Editorial Review: 4/30/2015 12:00:00 AM




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Many Car Crash Deaths Involve Alcohol Levels Below Legal Limit: Study

Title: Many Car Crash Deaths Involve Alcohol Levels Below Legal Limit: Study
Category: Health News
Created: 3/16/2020 12:00:00 AM
Last Editorial Review: 3/17/2020 12:00:00 AM




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Ride-Sharing Services Tied to Rise in Car Crashes

Title: Ride-Sharing Services Tied to Rise in Car Crashes
Category: Health News
Created: 4/7/2020 12:00:00 AM
Last Editorial Review: 4/8/2020 12:00:00 AM




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Spring Time Change Tied to More Fatal Car Crashes

Title: Spring Time Change Tied to More Fatal Car Crashes
Category: Health News
Created: 1/30/2020 12:00:00 AM
Last Editorial Review: 1/31/2020 12:00:00 AM




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A Sustained Immune Response Supports Long-Term Antiviral Immune Priming in the Pacific Oyster, Crassostrea gigas

ABSTRACT

Over the last decade, innate immune priming has been evidenced in many invertebrate phyla. If mechanistic models have been proposed, molecular studies aiming to substantiate these models have remained scarce. We reveal here the transcriptional signature associated with immune priming in the oyster Crassostrea gigas. Oysters were fully protected against Ostreid herpesvirus 1 (OsHV-1), a major oyster pathogen, after priming with poly(I·C), which mimics viral double-stranded RNA. Global analysis through RNA sequencing of oyster and viral genes after immune priming and viral infection revealed that poly(I·C) induces a strong antiviral response that impairs OsHV-1 replication. Protection is based on a sustained upregulation of immune genes, notably genes involved in the interferon pathway and apoptosis, which control subsequent viral infection. This persistent antiviral alert state remains active over 4 months and supports antiviral protection in the long term. This acquired resistance mechanism reinforces the molecular foundations of the sustained response model of immune priming. It further opens the way to applications (pseudovaccination) to cope with a recurrent disease that causes dramatic economic losses in the shellfish farming industry worldwide.

IMPORTANCE In the last decade, important discoveries have shown that resistance to reinfection can be achieved without a functional adaptive immune system, introducing the concept of innate immune memory in invertebrates. However, this field has been constrained by the limited number of molecular mechanisms evidenced to support these phenomena. Taking advantage of an invertebrate species, the Pacific oyster (Crassostrea gigas), in which we evidenced one of the longest and most effective periods of protection against viral infection observed in an invertebrate, we provide the first comprehensive transcriptomic analysis of antiviral innate immune priming. We show that priming with poly(I·C) induced a massive upregulation of immune-related genes, which control subsequent viral infection, and it was maintained for over 4 months after priming. This acquired resistant mechanism reinforces the molecular foundations of the sustained response model of immune priming. It opens the way to pseudovaccination to prevent the recurrent diseases that currently afflict economically or ecologically important invertebrates.




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US pedestrian deaths from vehicle crashes increasing in 30 states

Pedestrian fatalities from vehicle impacts in 2019 were the highest in the U.S. in over three decades, a February report finds.




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Crashing Out of a Career

This article is meant as a personal reflection on my unexpected retirement, and includes memories and thoughts about my career with the Indian Health Service near the border with Mexico, serving the Tohono O’odham tribe.




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MIG 29 Crash: पंजाब में भारतीय वायुसेना का विमान दुर्घटनाग्रस्त, पायलट सुरक्षित

अधिकारी ने बताया कि एक हेलीकॉप्टर से पायलट को बचाया गया और दुर्घटना की वजह पता लगाने के लिए कोर्ट ऑफ इंक्वायरी के आदेश दिए गए हैं।




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Kobe Bryant's widow files claim against LA County Sheriff's Department over crash-scene photos

Vanessa Bryant, the widow of late NBA star Kobe Bryant, filed a legal claim Friday against the Los Angeles County Sheriff’s Department over graphic photos that deputies allegedly took and shared of the helicopter crash scene where her husband, 13-year-old daughter, Gigi, and seven others were killed in late January.



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Compton crash: Cyclist in his 40s killed in collision with van

A cyclist has died after being involved in a collision with a van.




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South Norwood crash: Pedestrian killed 'in hit and run' as he crossed road in south London

A pedestrian has died after being hit by a black BMW as he crossed a road in south London.




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M11 closed near Chigwell after serious crash following police pursuit

Government advice continues to state that only journeys which are absolutely essential should be undertaken, and anyone travelling in the area should expect disruption and a longer journey time, with the road expected to remain closed for some time.




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New Russian plane crash footage shows passengers fleeing blaze that killed 41 people

New video footage released by Russian authorities shows the moment a plane's emergency landing resulted in a crash which killed 41 people in Moscow in 2019.




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Lower Clapton crash: Motorcyclist dies after crash on busy road in north-east London

A motorcyclist has died after a crash on a busy road in north-east London.




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Man charged with murder after woman killed in Barnet crash




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Motorcyclist, 35, dies after crash in Hackney

A 35-year-old motorcyclist has died after a crash in east London.




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Family members of four people killed in Kobe Bryant crash sue helicopter company

The families allege that the two helicopter companies were careless and negligent




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Alleged road rage killer Robert Barrow in court after woman run over in A406 crash row

An Essex man has appeared in court accused of fatally running over a woman after a row about a minor collision.




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Bombshell virus blow to economy with calls for path out of lockdown as output fall 'worse than 2008 crash'

Record falls in output accompanied by unprecedented jobs threat




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Crash near Harry Dunn collision site being probed by US airbase

The US military base near to where the crash which claimed Harry Dunn's life is "looking into" claims a staff member also drove on the wrong side of the road before hitting into a stone wall.




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Brent crash: Motorcyclist dies after collision in north London

A man has died after his motorbike crashed into the central reservation of a major London road.




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Grant Shapps denies coronavirus test website crashed as essential workes applied for screenings

But speaking at the daily Covid-19 Downing Street press conference, Mr Shapps revealed that there was popular demand for the test slots with 16,000 people registering on Friday morning alone. Around 5,000 also got home test kits. While around 46,000 had tried to apply through the site.




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Streatham crash: Woman in her 80s fighting for life after being hit by van in front of shocked witnesses

A woman in her 80s is fighting for her life after she was hit by a van in front of shocked onlookers on a major south London road.




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Mile-wide asteroid to pass Earth today at 19,000mph as NASA sets sights on crashing spacecraft into smaller one

Nasa plans to test potentially lifesaving technology by crashing a spacecraft into a smaller asteroid in 2021




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Dagenham crash: Police seek witnesses after man killed in hit-and-run




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Dagenham crash: Police release photo of man wanted after fleeing from fatal hit-and-run




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One police officer killed and another critically injured after Texas helicopter crash

A police helicopter has crashed in Texas, killing one of the two officers on board and critically injuring the other.




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Pedestrian rushed to major trauma centre after being 'trapped' between two cars during crash in north london




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Man pulls daughter, 7, to safety before 'horrific' crash leaves husband trapped between two vehicles

A man has told how he pulled his young daughter to safety before a "horrific" crash that left his husband trapped between two vehicles in north London.




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Streatham crash: Cyclist, 16, fighting for life after 'double hit-and-run' in south London






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Canadian Forces determining how to raise helicopter that crashed

The Canadian military is still determining how to raise the wreckage of a military helicopter that crashed into the Mediterranean Sea last week, Defence Minister Harjit Sajjan said Thursday.




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Big Night In: Coronation Street's Liz McDonald crashes EastEnders sketch

Liz McDonald crashed the Queen Vic's virtual pub quiz




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Jimmy Fallon's daughter gatecrashed her father's video interview with Jon Hamm

Mad Men actor played along as Winnie Fallon showed him her new colouring book




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Tracy Morgan's car crash recovery gives Tiffany Haddish hope for her mother

Tiffany Haddish's mother suffered severe brain damage following her crash.




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One Dead and 5 Missing After Canadian Military Helicopter Crashes off Greece

The Cyclone helicopter was participating in a NATO training exercise. A Nova Scotia native died, and two others from the province were missing.




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Cannabis employees are in high demand during economic crash

The industry is looking for thousands of workers across the country.




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Sydney news: NSW sexual consent laws strengthened, man stabbed after car crash in West Hoxton

MORNING BRIEFING: A proposal to bring NSW sexual consent laws in line with Victoria and Tasmania is introduced, while a man is rushed to hospital with multiple stab wounds after a two-vehicle crash.




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Sydney news: Sydney air quality reach 'hazardous' level due to smoke haze, traffic delays on M1 after multi-truck crash

MORNING BRIEFING: Eastern suburb residents are particularly at risk after smoke haze blankets Sydney, and a north-bound lane on M1 remains closed after four trucks caught fire after a collision




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Report says Ashley ‘Ms. Minnie’ Ross At Fault in Fatal Crash



She lost control of her car and swerved lanes, report says




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Lilly's World Comes Crashing Down



Donald's secret is out in the open.




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BGT's furious David Walliams threatens to sue Simon Cowell after backstage crash

The Britain's Got Talent judges come crashing into tonight's auditions when Simon can't work the breaks - leaving David to claim he has whiplash