gen

Traditional healers told not to treat infants, children to prevent mortalities in Chintoor agency

The methods and ingredients used in the preparation of Ayurvedic medicine by traditional healers are to be suspected, says an official




gen

Compact Riemann surfaces [electronic resource] : an introduction to contemporary mathematics / by Jürgen Jost

Berlin ; Heidelberg : Springer-Verlag Berlin Heidelberg, 2006




gen

Uniform output regulation of nonlinear systems [electronic resource] : a convergent dynamics approach / Alexey Pavlov, Nathan van de Wouw, Henk Nijmeijer

Boston : Birkhäuser, 2006




gen

Tropical algebraic geometry [electronic resource] / Ilia Itenberg, Grigory Mikhalkin, Eugenii Shustin

Basel ; Boston : Birkhauser, 2007




gen

Riemannian geometry and geometric analysis [electronic resource] / Jurgen Jost

Berlin : Springer, 2005




gen

Postmodern analysis [electronic resource] / Jürgen Jost

Berlin : Springer, [2005]




gen

General theory of information transfer and combinatorics [electronic resource] / Rudolf Ahlswede [and others] (eds.)

Berlin ; New York : Springer, [2006]




gen

Values never go out of fashion, says Director General of ICMR

Rajiv Bahl was delivering the 32nd convocation address of MAHE on the last day of convocation.




gen

Online education: How Gen Z and millennials can leverage it for career growth

Transformative online education in India for Gen Z and millennials, driving growth and innovation, faces challenges of inclusivity and credibility.




gen

Kotigobba 2 review: A self-indulgent star vehicle




gen

Kidaari: new genre of 'Aruvaa Christie'?

It’s not a good sign when the story seems less interested in suspense than in sickles whooshing down every few minutes.




gen

Multi-step chirality transfer and racemization kinetics of pillar [5]arenes by tuning the halogen substituents on the rims

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01799D, Research Article
Lizhi Fang, Xiaowen Guan, Yanling Shen, Dayang Zhou, Long Chen, Xiaochuan Chen, Wanhua Wu, Leyong Wang, Cheng Yang
Halogen-substituted pillar[5]arenes exhibited hindered hydroquinone subunit flipping, enabling enantioseparation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Shaping cycles with light: a regiodivergent approach to tetracyclic aza-aromatic compounds

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01606H, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Clara Mañas, Belén Ibarra, Estíbaliz Merino
We present a novel visible light-promoted regiodivergent cyclization, enabling the selective synthesis of distinct azapolyaromatic regioisomers from 2-alkynlazobenzenes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Visible-light heterogeneous photocatalysis with an ionic porous organic polymer (IPOP): synthesis of β-keto sulfoxides and benzothiophene diesters by tandem radical addition–oxidation reactions

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01382D, Research Article
Ajay Kumar Sahoo, Parag Tamuly, Jarugu Narasimha Moorthy
An IPOP, constructed constructed from cyanuric chloride and the readily accessible 2,5-di(pyridin-4-yl)thiazolo[5,4-d]thiazole (BpyTzTz), is shown to exhibit excellent visible light absorption and serve as a metal-free heterogeneous photocatalyst.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Unravelling the different pathways of cyclohexene oxidation via a peroxyl radical generated from tert-butyl hydroperoxide (TBHP) by various metal salts

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01681E, Research Article
Lu-Jian Zhou, Xiao-Hui Liu, Han-Wen Zhang, Can Xue, Han-Kang Zhong, Xian-Tai Zhou
Two different mechanisms were obtained in the selective oxidation of cyclohexene catalyzed by CuCl2 and VCl3 respectively in presence of TBHP. The two opposed mechanisms are mainly caused by the roles of the t-BuOO˙ radical in catalytic oxidations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Lewis acid-controlled Pd-catalyzed chemodivergent hydrocyanation of cyclopropenes

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01609B, Research Article
Rongrong Yu, Song-Zhou Cai, Xianjie Fang
We report a Lewis acid-controlled Pd-catalyzed chemodivergent hydrocyanation of cyclopropenes. In the absence of Al Lewis acid, the reaction predominantly yields ring-opened allylic nitrile products while the addition of Lewis acid favors the formation of cyano-substituted cyclopropane products.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

General ppm-level Pd-catalysed asymmetric diarylalkyne hydrosilylation to access structurally diverse Si-stereogenic vinylsilanes

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01698J, Research Article
Heng Xu, Han-Xiao Yu, An-Jiu Wen, Fang-Ying Ling, Fei Ye, Li Li, Fuk Yee Kwong, Li-Wen Xu
The first example of enantioselective Pd-catalyzed hydrosilylation of symmetric and asymmetric diarylalkynes to access novel Si-stereogenic vinylsilanes with excellent ee and a high TON is realized under mild reaction conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Mechanistic insight into the dehydrogenation reaction catalyzed by an MLC catalyst with dual ancillary ligand sites

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01767F, Research Article
Gui-Xiang Zhou, Cheng Hou
This study reveals a mechanism in which a ruthenium complex catalyst improves catalytic efficiency and lowers the energy barrier in the dehydrogenation of benzyl alcohol by dynamically switching ligand sites.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Photocatalytic arylation/alkylation of olefins/alkynes via halogen-atom transfer mediated by NHC-BH3

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01562B, Research Article
Xinhan Li, Yao Zhong, Fengsong Tan, Yusong Fei, Xiaohan Zhao, Jianbin Xu, Baomin Fan
A versatile method for radical reductive cross-coupling of iodides and activated olefins under mild conditions, facilitated by NHC-BH3 through photocatalysis, was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Photoinduced cobaloxime catalysis for allylic mono- and diphosphinylation of alkenes with hydrogen evolution

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01638F, Research Article
Aijun Zhang, Miao-Miao Li, Lei Guo, Huaixiang Yang, Jiefei Guo, Da Xu, Wei Ding
A highly efficient allylic radical mono- and diphosphinylation of alkenes with secondary phosphine oxides is developed, via visible-light-induced cobaloxime catalysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

The reactivity of alkenyl boron reagents in catalytic reactions: recent advances and perspectives

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01703J, Review Article
Ya-Li Feng, Bo-Wen Zhang, Youzhi Xu, Shengnan Jin, Daniele Mazzarella, Zhong-Yan Cao
Recent advances focusing on novel reactivity of alkenyl boron reagents in polar or radical pathways within catalytic reactions by employing transition metal catalysis, organocatalysis have been summarized and discussed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Transition-metal-catalyzed regiodivergent sulfonylation of aziridrines for the synthesis of β-amino sulfones

Org. Chem. Front., 2024, 11,6340-6346
DOI: 10.1039/D4QO01376J, Research Article
Qinqiong Zeng, Yujia Gong, Xiaochun He, Xuemei Zhang, Zhong Lian
We developed the first transition-metal-catalyzed, regiodivergent sulfonylation of aziridines, enabling the efficient synthesis of diverse β-amino sulfones under mild conditions with broad substrate compatibility and high regioselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Phosphine-controlled divergent reactions of MBH-carbonates with azaheptafulvenes: access to o-anilinyl diene and benzazepine derivatives

Org. Chem. Front., 2024, 11,6418-6425
DOI: 10.1039/D4QO01298D, Research Article
Wei Hao, Yiwen Zhang, Xiao Han, Zhen Wang, Weijun Yao
A phosphine controlled divergent cascade reaction of MBH-carbonates with azaheptafulvenes was disclosed. PPh3 provided o-aminophenyl diene while PCy3 offered benzazepine derivative through formal [8 + 3] annulation/ring contraction cascade.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

18F-labelling of nitrogen-containing aryl boronates – anti-cancer drug melflufen as a case study

Org. Chem. Front., 2024, 11,6411-6417
DOI: 10.1039/D4QO01594K, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kevin Bajerke, Fredrik Lehmann, Gunnar Antoni, Kálmán J. Szabó
This study addresses the 18F-labelling of nitrogen-containing arenes via copper-mediated radiofluorination (CMRF). In this case study, derivatives/fragments of the anti-cancer drug melflufen were targeted.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

A general method for E-selective olefination of acylsilanes with isocyanides via silver catalysis

Org. Chem. Front., 2024, 11,6450-6458
DOI: 10.1039/D4QO01528B, Research Article
Xiu-Xia Liang, Dan-Ni Yang, Xiao-Hui Yan, Peng Wang, Man-Yi Han
A silver-catalyzed olefination reaction between acylsilanes and isocyanides is developed, resulting in E-vinylsilanes with good yields and high stereoselectivities.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Carbonate-assisted selectively deoxygenative cross-coupling reaction between aryl and aliphatic aldehydes: a straightforward route to access α-alkylated aryl ketones

Org. Chem. Front., 2024, 11,6510-6517
DOI: 10.1039/D4QO01517G, Research Article
Yu Sun, Yi Wang, Zhijun Zuo
A novel reductive cross-coupling reaction of two different aldehydes for rapidly assembling α-alkylated aryl ketones has been developed. The inexpensive carbonate served not only as a base but also as an efficient electron donor.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Charge Transfer Complex Enabled Mechanochemical Synthesis of Chalcogenoacetylenes via Alkynyl Radicals

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01827C, Research Article
Open Access
Fang Tan, Chang-Zhen Fang, Bing-Sheng Qiu, He Sheng, Yong-Liang Tu, Xiang-Yu Chen
Mechanochemistry has become an appealing strategy to enable numerous organic transformations. While significant advances have been achieved, the radical coupling reaction under mechanochemical conditions is still in its infancy. In...
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Nickel-catalyzed reductive 1,2-alkylarylation of alkenes via a 1,5-hydrogen atom transfer (HAT) cascade

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01875C, Research Article
Xi Chen, Qiang Wang, Xiao-Ping Gong, Rui-Qiang Jiao, Xue-Yuan Liu, Yong-Min Liang
A nickel-catalyzed 1,2-alkylarylation of alkenes has been developed, leveraging amidyl radical-triggered 1,5-HAT with electrophiles as functionalizing reagents.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Influence of hydrogen bonds and π-π stacking on the self-assembly of aryldipyrrolidones

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01577K, Research Article
Open Access
Pedro Ximenis, Llorenç Rubert, Heike Ehmann, Bartolome Soberats
We report on the self-assembly behaviour in solution and solid-state of two newly designed bisdendronized aryldipyrrolidones (BDP and NDP) dyes with two free N-H at the lactam positions. Interestingly, while...
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Modular dehydrogenative cross-nucleophile coupling for direct construction of tetrasubstituted carbons

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01641F, Research Article
Peng Wang, Qiang Wang, Meng Wang, Liang Wang, Lubin Xu, Xiong-Li Liu, Fangzhi Hu, Shuai-Shuai Li
An FeCl3-catalyzed cross-dehydrogenative coupling reaction for the construction of various types of C–Y (Y = C, N, O, S) bonds with air as a green oxidant.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Convergent Synthetic Approaches to Polycyclic Aromatic Dicarboximides

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01828A, Review Article
Kazutaka Shoyama, Frank Wuerthner
Polycyclic aromatic dicarboximides (PADIs) as represented by naphthalene and perylene bis(dicarboximide) are useful molecules for a variety of functional materials and remain important synthetic targets for organic chemists. In this...
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Telangana pharmaceutical industries logged 97 major fire accidents in past decade: Fire Services Director-General Y. Nagi Reddy

The new government would like to decentralise and set up pharma villages, in 10 clusters, Special Chief Secretary Jayesh Ranjan said




gen

Key agent in Cambodia job racket arrested in Delhi




gen

Eleven transgenders arrested for public nuisance in Cyberabad




gen

NewGen stars have a chance to shine as Proteas challenge awaits 

It is imperative for them to shed the tag of sidekicks and establish themselves as the first-choice players in this format.




gen

Graphene-supported organoiridium clusters catalyze N-alkylation of amines via hydrogen borrowing reaction

RSC Adv., 2024, 14,35163-35171
DOI: 10.1039/D4RA06595F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tsun-Ren Chen, Siang-Yu Chiu, Wen-Jen Lee, Yi-Siou Tsai, Yu-Sheng Huang
Graphene-supported organic iridium clusters (GSOIC) exhibit excellent N-alkylation on various substrates under green processes.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Enhanced surface functionalization of 2D molybdenum/tin chalcogenide nanostructures for effective SERS detection of Escherichia coli

RSC Adv., 2024, 14,35021-35034
DOI: 10.1039/D4RA05315J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zainab Ishfaq, Layla A. Almutairi, M. Yasir Ali, Salhah Hamed Alrefaee, Mohamed Abdelsabour Fahmy, Elsammani Ali Shokralla, Lamiaa G. Alharbe, Adnan Ali, Arslan Ashfaq, A. R. Abd-Elwahed
This study enhances MoS2/SnS2 nanoparticles for SERS, functionalizing them with L-cysteine. Successful detection of E. coli demonstrates their potential as cost-effective SERS substrates for real-world applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Correction: Sustainable polymeric adsorbents for adsorption-based water remediation and pathogen deactivation: a review

RSC Adv., 2024, 14,35104-35104
DOI: 10.1039/D4RA90129K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Huda Alkhaldi, Sarah Alharthi, Salha Alharthi, Hind A. AlGhamdi, Yasmeen M. AlZahrani, Safwat A. Mahmoud, Lamiaa Galal Amin, Nora Hamad Al-Shaalan, Waleed E. Boraie, Mohamed S. Attia, Samera Ali Al-Gahtany, Nadiah Aldaleeli, Mohamed Mohamady Ghobashy, A. I. Sharshir, Mohamed Madani, Reem Darwesh, Sana F. Abaza
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Design, synthesis, biological evaluation, and in silico studies of novel N-substituted-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamides as promising anticancer agents

RSC Adv., 2024, 14,35323-35335
DOI: 10.1039/D4RA04492D, Paper
Open Access
Navid Dastyafteh, Manica Negahdaripour, Mohammad Hosein Sayahi, Mina Emami, Younes Ghasemi, Elham Safaei, Homa Azizian, Zahra Pakrouh Jahromi, Mehdi Asadi, Mohammad Reza Mohajeri-Tehrani, Fateme Zare, Minoo Shahidi, Zahra Pooraskari, Sayed Mahmoud Sajjadi-Jazi, Bagher Larijani, Mohammad Mahdavi, Sara Ranjbar
Synthesis and cytotoxicity evaluation of novel benzimidazoles were explained. The most potent derivative was subjected to cell cycle, apoptosis, and in silico investigations. Compound 5o proved to be a promising anticancer agent.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Macroporous chitosan/alginate hydrogels crosslinked with genipin accumulate and retain glioblastoma cancer cells

RSC Adv., 2024, 14,35286-35304
DOI: 10.1039/D4RA06197G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lauriane Parès, Sahar Naasri, Lisa Delattre, Hélène Therriault, Benoît Liberelle, Gregory De Crescenzo, Marc-Antoine Lauzon, Nathalie Faucheux, Benoit Paquette, Nick Virgilio
This work demonstrates how macroporous hydrogels can be prepared with porous polylactide molds, and homogeneous solutions of sodium alginate and chitosan crosslinked with genipin, in order to accumulate glioblastoma cancer cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Advanced oxidative degradation of monoethanolamine in water using ultraviolet light and hydrogen peroxide

RSC Adv., 2024, 14,33223-33232
DOI: 10.1039/D4RA05590J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Atif Khan, Saima Yasin, Hamayoun Mahmood, Shabana Afzal, Tanveer Iqbal
Development of an eco-friendly and commercially feasible method for monoethanolamine (MEA) degradation in aqueous phase using ultraviolet/hydrogen peroxide (UV/H2O2) advanced oxidation process (AOP).
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Chronological effects of oxygen on the structural transformations of polyacrylonitrile fibers during the rapid thermal stabilization process

RSC Adv., 2024, 14,35560-35567
DOI: 10.1039/D4RA06327A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Shiyang Li, Liang Chen, Jie Liu, Yixin Li, Jian Tang, Rongchao Jiang, Xiaoxu Wang
The effects of oxygen on the structure changes of PAN fibers during the rapid thermal stabilization are chronological, including thermal-driven dehydrogenation, oxidation and cyclization in the shorter, intermediate and longer periods, respectively.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Advances in quinoxaline derivatives: synthetic routes and antiviral efficacy against respiratory pathogens

RSC Adv., 2024, 14,35400-35423
DOI: 10.1039/D4RA04292A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fateme Dehnavi, Malihe Akhavan, Ahmadreza Bekhradnia
3D lung visualization showing COVID-19 infection areas alongside respiratory pathogens. The antiviral drug structure and comparison of healthy vs. infected lungs demonstrate how the drug could restore lung health.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents

RSC Adv., 2024, 14,35239-35254
DOI: 10.1039/D4RA06704E, Paper
Open Access
Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. Goda
In response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Complexes between 2,2'-azobis(2-methylpropionamidine) dihydrochloride (AAPH) and cucurbit[n]uril hosts modulate the yield and fate of photolytically-generated AAPH radicals

RSC Adv., 2024, 14,35980-35991
DOI: 10.1039/D4RA07150F, Paper
Open Access
Angie C. Forero-Girón, Mauricio Oyarzún, Kevin Droguett, Denis Fuentealba, Soledad Gutiérrez-Oliva, Barbara Herrera, Alejandro Toro-Labbé, Eduardo Fuentes-Lemus, Michael J. Davies, Camilo López-Alarcón, Margarita E. Aliaga
AAPH-cucurbit[n]uril systems were experimentally and theoretically studied. Radical yields formed upon photolysis of AAPH were altered by complexation with CB[8] in a stoichiometry-dependent manner, however, radical yields were not changed by CB[6].
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

In silico molecular docking and ADMET prediction of biogenic zinc oxide nanoparticles: characterization, and in vitro antimicrobial and photocatalytic activity

RSC Adv., 2024, 14,36209-36225
DOI: 10.1039/D4RA06890D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hajara Akhter, Susmita Sarker Ritu, Shahariar Siddique, Fariha Chowdhury, Rehnuma Tasmiyah Chowdhury, Samina Akhter, Mahmuda Hakim
A facile green route to synthesize zinc oxide nanoparticles using watermelon rind extract with antimicrobial and photocatalytic potential.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

Applications and interventions of polymers and nanomaterials in alveolar bone regeneration and tooth dentistry

RSC Adv., 2024, 14,36226-36245
DOI: 10.1039/D4RA06092J, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Prashish Sharma, Sushmita Saurav, Zeba Tabassum, Bhawana Sood, Anil Kumar, Tabarak Malik, Anand Mohan, Madhuri Girdhar
Inflammatory diseases exert a significant influence on the periodontium, serving as a primary contributor to the development of periodontitis and alveolar bone loss.
The content of this RSS Feed (c) The Royal Society of Chemistry




gen

‘Public emergency’ in six Nagaland districts suspended

The move was to facilitate talks with the Centre on the creation of the autonomous Frontier Nagaland Territory, said the Eastern Nagaland People’s Organisation




gen

Indian GP: Yugendran leaps to a new meet record in men’s pole vault

Baranica secures the gold in women’s event; Vithya Ramraj claims the women’s 400m hurdles title; Abha bags the shot put top spot




gen

From childhood restrictions to international glory, a septuagenarian’s remarkable athletic journey