ana

Detection of Free DNA Based on Metal-Enhanced Fluorescence Triggered by CRISPR-Cas12a and Colorimetric Analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00149D, Paper
Ming-Qiu Zheng, Yuyao Li, Liling Zhang, Cheng-Yu Li, Menghan Liu, Hongwu Tang
The CRISPR-Cas system has been found to be extremely sensitive and there is an urgent demand to extend its potential in bioassay. Herein, we developed a novel nanobiosensor to detect...
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ana

Paper-based sensors: affordable, versatile, and emerging analyte detection platforms

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02258G, Critical Review
Open Access
Sumit Malik, Joginder Singh, Kajal Saini, Vivek Chaudhary, Ahmad Umar, Ahmed A. Ibrahim, Sheikh Akbar, Sotirios Baskoutas
The schematic representation of distance based paper sensor to identify lead in food samples.
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Electroanalysis overview: additive manufactured biosensors using fused filament fabrication

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00278D, Minireview
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Robert D. Crapnell, Craig E. Banks
Additive manufacturing (3D-printing), in particular fused filament fabrication, presents a paradigm shift in the way electrochemical based biosensing platforms are produced, giving rise to a new generation of personalized and on-demand biosensors.
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ana

Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00487F, Paper
Jinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang Liu
Small extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...
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Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00246F, Paper
Bingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo He
In order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.
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ana

​Heartland murmurs: On the Haryana Assembly elections

Haryana may throw up surprises after the realignments




ana

​Flipping scripts: On the Haryana and J&K election results  

BJP and INDIA bloc emerge clear winners in Haryana and Jammu & Kashmir




ana

​Against the odds: On the 2024 Haryana Assembly elections

The Congress could not counter the caste polarisation in Haryana 




ana

Canadian frostbite: On the India-Canada diplomatic war

India must consider the impact of its next steps on its diplomacy and image




ana

​Complicit: On India and the U.S and Canada cases

India must come clean on its stance on transnational killings 




ana

Ananya-Suhana Party Together

Ananya Panday celebrated her birthday with family and the media, but she really wasn't done yet.




ana

A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker

RSC Med. Chem., 2024, 15,3444-3459
DOI: 10.1039/D4MD00318G, Research Article
Anuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar Maiti
Niloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.
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ana

Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00594E, Research Article
Nagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza Elrayess
One benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.
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ana

Continuous flow synthesis of N,N-dimethyltryptamine (DMT) analogues with therapeutic potential

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00562G, Research Article
Open Access
Andreas Simoens, Andreas Dejaegere, Marthe Vandevelde, Christian V. Stevens
Flow chemistry allows for the rapid and clean synthesis of therapeutically relevant tryptamines in good yields, including the large scale drug rizatriptan.
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ana

A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00632A, Review Article
Ashish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Mahendra Pratap Singh, Abhay M. Gaidhane, Sorabh Lakhanpal, K. Nagendra Prasad, Bhupinder Kumar
The present review is a concerted effort to cover drugs bearing pyridine rings approved in the last decade, and it provides thorough discussion and commentary on their pharmacokinetics and pharmacodynamics together with in-depth structural analysis.
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ana

Synthesis, in silico and bio-evaluation studies of new isothiocyanate derivatives with respect to COX inhibition and H2S release profiles

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00495G, Research Article
Yakup Berkay Yilmaz, Tuğba Güngör, Serhat Dönmez, Hazal Nazlıcan Atalay, Pınar Siyah, Serdar Durdağı, Mehmet Ay, Tugba Boyunegmez Tumer
New isothiocyanate derivatives (I1–3 and I1a–e) were synthesized and screened for their anti-inflammatory activities and H2S-releasing capacities. Compounds I1 and I1c demonstrated the most potent and selective COX-2 inhibition.
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ana

Heavy weed growth at Kasi Viswanathar Temple tank prevents replenishing of underground water table, say Tiruchi residents




ana

Live Cricket Scores, Cricket News, Analysis, Results & More | The Hindu




ana

561: Web Perf News, Web Sommelier, Data Analytics, and Passkeys

Topics for this one include how do you learn about web performance news? Do you need a web components sommelier? Our thoughts on Syntax going to Sentry, and being able to focus on the things you want to focus on. Passkeys, Arc split screen, and vibe driven development.




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597: How Many VS Code Plugins, Poor Charlie’s Almanack, and Where to Start in 2024?

We're closing in on episode 600 and need your help to celebrate! Listen in to learn how to contribute to the episode. We're also talking GitHub desktop apps and code editors, how many VS Code plugins are needed, reading long form like Poor Charlie's Almanack, InVision shutting down, and answering our first Q of the year: how would you approach learning web development in 2024?




ana

The management of sludge

There is a need for building bye-laws to insist on a range of on-plot sanitation as mandatory, depending on the location and the groundwater table.




ana

Flat organisation believers: Can you imagine a world without managers?

What does a manager do that we keep hiring new ones or keep promoting more of them? Which managerial layer is the most important?




ana

Haryana Congress to move court over ‘violations’ by BJP during Assembly poll

Panel to gather information from party’s candidates about various violations




ana

Stubble burning in Punjab, Haryana | Caught in the cross (farm) fire

Despite the reduction in stubble burning over the years, farmers say the lack of incentive, plus the high cost of machines, pushes them to set fields on fire after harvesting paddy at the start of every winter.  The Hindu reports on the practice in Punjab and Haryana that causes smoke to drift across north India’s Gangetic plain




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Issue of infiltration in Santhal Pargana was raised, Hemant did not listen: Champai Soren

The longtime JMM-loyalist, who has now switched to the BJP, adds that decisions he had taken as CM — on tribal language education, PESA implementation, and jump-starting state recruitments — have been put on hold now




ana

Man stabs mother in Delhi’s Badarpur for not ‘allowing him’ to migrate to Canada




ana

Security upped outside Canadian High Commission due to protest against temple attack

The Hindu Sikh Global Forum members are marching towards the High Commission in the Chanakyapuri area




ana

Pranab’s Presidential years

A matter-of-fact, yet reflective, memoir of a veteran politician




ana

The rise and fall of Rana Kapoor

The book sheds light on the journey of value creation and callous destruction by YES Bank’s promoter




ana

In love with operations management

The author brings aesthetics into a field obsessed with quantification




ana

DGCA approves Drone Academy at Telangana Agri University

It offers six-week training to ryots, agri-graduates, rural youth in drone piloting




ana

Eyebrows raised as Central team visits Anantapur to assess rabi drought during rainy kharif

The team choosing mandals like Vidapanakallu and Vajrakarur which received excessive rain in June, draws flak from farmers and district officials alike; farmers worry as to how to present their drought woes to the officials who are visiting their fields which are now rain-fed and green




ana

Watch: What is Makhana and why is it in high demand?

The people who harvest the seeds of the high-protein crop say the government offers them little support, and they now want a minimum support price to ensure that the crop is sustainable for cultivation




ana

Anantapur Collector urges farmers to adopt natural practices

V. Vinod Kumar visits several watershed structures in the district implemented by Accion Fraterna Ecology Centre with funding from NABARD




ana

Home cooks in Thiruvananthapuram are championing artificial additive-free jams, preserves, juice, ethnic eats and more

Four home cooks in Thiruvananthapuram are turning fruits into value-added products without using artificial flavours or preservatives




ana

The certainty trap [electronic resource] : why we need to question ourselves more--and how we can judge others less / Ilana Redstone ; foreword by Joe Walsh.

Durham, North Carolina : Pitchstone Publishing, [2024]




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Domestic investment bankers outpace global brands in managing IPOs

The list of top 10 investment banks this year includes only one foreign entity.




ana

Local investment banks edge out global brands in managing IPOs

Domestic banks win on consistency, efficiency; HSBC is only foreign bank on top-10 list




ana

Hindu Tamil Thisai journalist Kalyanasundaram dies at 50




ana

Kamal Haasan tells people, fans to not address him as ‘Ulaganayagan’

The star also requested his fans, members of the film fraternity, media, party cadres and ‘fellow Indians’ to refer to him ‘simply as Kamal Haasan or Kamal or KH’




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Crocodile Conservation Centre to come up at Anaikarai

The Centre is to be established at a cost of ₹2.5 crore based on a detailed proposal sent by the Principal Chief Conservator of Forests and Chief Wildlife Warden, Chennai




ana

Samayamoorthy is HRM Secretary, Atul Anand is MSME Secretary




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Drop deformation in a planar elongational flow: impact of surfactant dynamics

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00642A, Paper
Julian Wailliez, Paul Regazzi, Anniina Salonen, Paul G. Chen, Marc Jaeger, Marc Leonetti, Emmanuelle Rio
We measure the deformation of a drop under an extensional flow. The drop is less deformed than for a pure liquid because of the depletion of surfactants at the tips, which we attribute to the adsorption/desorption dynamics of the surfactants.
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Bubbles and drops between circular frames: shape, force and stability analysis

Soft Matter, 2024, 20,8420-8435
DOI: 10.1039/D4SM00919C, Paper
Open Access
Friedrich Walzel, Jonathan Dijoux, Leandro Jacomine, Élodie Harle, Pierre Muller, Thierry Charitat, Wiebke Drenckhan
Combining experiments, simulations and theory, we provide a complete shape analysis of two bubbles held by circular frames in the parameter space of different frame radii, distances between frames and contact angle between bubbles (0°, 60° and 90°).
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Banana DNA derivatives as homeotropic alignment layers in optical devices

Soft Matter, 2024, 20,8561-8569
DOI: 10.1039/D4SM00322E, Paper
Rafał Węgłowski, Anna Spadło, Dorota Węgłowska
In this study, DNA extracted from bananas was functionalized and used as a homeotropic alignment layer for liquid crystals.
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Effects of Hydration Water on Bioresponsiveness of Polymer Interfaces Revealed by Analysis of Linear and Cyclic Polymer–Grafted Substrates

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00977K, Paper
Open Access
Shin-nosuke Nishimura, Naoya Kurahashi, Shohei Shiomoto, Yoshihisa Harada, Masaru Tanaka
Given that the hydration water of polymer matrices may differ from that of outermost polymer surfaces, processes at biomaterial–biofluid interfaces and role of hydration water therein cannot be adequately examined...
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Editorial. Churn in Haryana

BJP defends its 10-year rule against a resurgent Congress




ana

Editorial. BJP’s remarkable show in Haryana; NC wrests J&K  

BJP wins in Haryana for third successive time




ana

Bank unions push back against government ‘micromanagement’ in employee performance reviews

More than 1 lakh bank employees likely to be affected by DFS instruction to banks, says AIBEA General Secretary Venkatachalam



  • Money & Banking

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Canara Bank beats estimate, reports 11% growth in net profit to ₹4,014 crore in Q2FY24

Global deposits were ₹13,47,347 crore, up by 9.34 percent, while gross advances reached ₹10,11,997 crore growing by 9.53%



  • Money & Banking