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Nanotechnology-based delivery of therapeutics through the intranasal pathway and the blood–brain barrier for Alzheimer's disease treatment

Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article
Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Applications of hydrogels in tissue-engineered repairing of temporomandibular joint diseases

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM01687K, Review Article
Xuan Wang, Fushuang Liu, Tianyi Wang, Yikai He, Yongwen Guo
Epidemiological studies reveal that symptoms of TMD occur in 60-70% of adults. The inflammatory damage caused by TMD can easily lead to defects in the articular disc, condylar cartilage, subchondral...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Beyond Nanoparticle-based Oral Drug Delivery: Transporter-mediated Absorption and Disease Targeting

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00313F, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hana Cho, Kang Moo Huh, Hyun Ji Cho, Bogeon Kim, Min Suk Shim, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Young Jik Kwon, Han Chang Kang
Various strategies in the microscale/nanoscale have been developed to improve oral absorption of therapeutics. Among them, gastrointestinal (GI)-transporter/receptor-mediated nanosized drug delivery systems (NDDSs) have drawn attention due to their many...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Asus Vivobook S15 review: Ready to rise?

Slim, Snapdragon-powered and raring to go — but hold the games!




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Lenovo launches business and enterprise line-up

Unveils ultra-light ThinkPad laptops at Lenovo Innovation World 2024




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The need to differentiate between entrepreneurship education and enterprise education

How is enterprise education different from entrepreneurship education? Why do students need both?




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Aca Sports Counselling in Hyderabad integrates sports and academics, providing personalised guidance to athletes

Padmavathi Devarakonda’s Aca Sports Counselling in Hyderabad blends the spirit of sports with academic guidance to help aspiring athletes achieve their dreams




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UPSC aspirants club inaugurated in Tirunelveli; CoP calls students to utilise the opportunity




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NAMAHA Marathon to be organised in Visakhapatnam on November 10




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Chhath Puja to be organised at RK Beach in Visakhapatnam on November 7




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Competitions for schoolchildren to raise awareness on eye problems




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ENC conducts anti-hijack exercise at Visakhapatnam Airport to test response procedures




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SIDAR organises discussion with intellectuals at Dr L Bullayya College in Visakhapatnam




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Naval Officer trains A.P. Marine Police and lighthouse personnel for Exercise Sea Vigil 2024




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‘Punya nadhi harathi’ to be organised at Sri Varaha Pushkarini in Visakhapatnam on November 15




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10 students of private junior college in Visakhapatnam hospitalised due to suspected food poisoning

The District Medical & Health Officer visits the private hospital where the affected students are currently being treated as well as the college hospital; all students are out of danger, informs Collector




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Oakridge International School organises Model United Nations in Visakhapatnam

The objective of the programme is to enable school students to step into the roles of country delegates to debate, negotiate and collaborate on real-world problems




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The Rise Of The Mid-Range Movie Hit

While super hits like Jawaan are missing this year, it has been filled with a range of medium-range hits such as Crew, Teri Baaton Ne Uljhaa Diya and Guntur Kaaram, observes Vanita Kohli-Khandekar.




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The Failed Promise of Indian 2

Kamal Haasan is right where he left off from the first film but there is only so much he can do to salvage an already lost cause, observes Arjun Menon.




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Block printing & book illustration in Japan / by Louise Norton Brown ; with forty-three plates (eighteen in colours). and copious indexes of titles and artists.

London : George Routledge & Sons, Ltd. ; New York : E. P. Dutton & Co., 1924.




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Bacon is Shake-speare, by Sir Edwin Durning-Lawrence, bt. Together with a reprint of Bacon's Promus of formularies and elegancies collated, with the original MS. by the late F. B. Bickley and revised by F. A. Herbert, of the British Musuem.

London : Gay & Hancock, Ltd., 12 & 13, Henrietta Street, Covent Garden, W.C., and New York, MCMX. [1910]




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I disegni di Leonardo da Vinci e della sua cerchia nelle collezioni della Gran Bretagna / ordinati e presentati da Martin Kemp e Juliana Barone.

[Firenze] : Giunti, 2010.




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Dyson Airstrait review: The straightener, now launched in India, promises no heat damage. Does it deliver?

Dyson returns to India with its latest no-heat damage hair styler and dryer, the Airstrait, in Delhi. Does it deliver on its promise?




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Mumbai| The Wedding Collective promises the A to Z of the wedding planning experience, under one roof

A three day exhibition, The Wedding Collective brings together over 100 different brands in fashion, jewellery, gifting, wedding design and more at the Jio World Convention Centre from August 23 to 25



  • Life & Style

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Head over heels: Behind Christian Louboutin’s Miss Z launch at Paris Fashion Week with synchronised Olympic swimmers

In Mumbai to launch The Diwali Edit, Christian Louboutin, the inimitable shoe designer talks about getting the French Olympic artistic swimming team to perform underwater in spiky stilettos




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‘Shocking’: Ananya Panday, Sonam Kapoor, Manish Malhotra, mourn demise of fashion designer Rohit Bal

From Bollywood actors to designer Manish Malhotra, many took to social media to pay their respects to Rohit Bal, affectionately known as 'Gudda' by his admirers




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Design should be localised

For the sake of insulation and ventilation, structures should be built in tune with the prevailing climatic conditions. By Sathya Prakash Varanashi




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Approvals for high-rises

G. Shyam Sundar lists mandatory norms for constructing multi-storeyed buildings in Tamil Nadu




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Budget 2024: Prudent as expected with promise of bigger things

The government stuck to the theme as it raised the capex outlay for the coming financial year to Rs.11.11 lakh crore, an increase of 11%




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Budget 2024 | The pace of fiscal consolidation took everyone by surprise

‘The underlying theme was clearly fiscal consolidation with an ability to maintain the infrastructure spends at the existing run rate’




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Death in Gujarat Refinery fire rises to 2; IOCL constitutes team to investigate

The fire that began on Monday afternoon with a blast in a benzene storage tank of the refinery later spread to two other adjoining tanks, Jawahar Nagar police station inspector A B Mori said




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Bank Nifty Prediction Today – November 12, 2024: Bearish. Go short now and on a rise

Bank Nifty November Futures can fall to 51,500 and even 51,250




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Urban gardening company Ugaoo raises ₹47 crores in Series A funding led by V3 Ventures

The company plans to use the funds to expand its regional presence across the top 10 Indian cities and open 80 retail stores by FY 2030




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Zydus Lifesciences reports 13.7 per cent rise in Q2 net

The revenues rose 20 per cent to ₹5,237 crore for the period




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New flights to Uzbekistan, Vietnam on cards as govt revises air service agreement

This move follows a revision in air services agreement between India and the two countries at an International Civil Aviation Organisation gathering in Malaysia last month




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Apple drops plan to raise iPhone output on faltering demand

Demand for Apple’s higher-priced iPhone 14 Pro models is stronger than for entry-level versions: Sources



  • Mobiles & Tablets

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Govt may soon standardise mobile screen guards to protect domestic manufacturing

The Centre losses crores of rupees due to unorganised screen guard imports from China



  • Mobiles & Tablets

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Apple's iPhone seen gaining market share in India as Pro model demand rises

The company is projected to account for 7 per cent of all smartphone sales in the country from July to December, up from 5 per cent in the first half of 2023



  • Mobiles & Tablets

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Apple apologises for iPad Pro 'Crush' ad, Ad Age says

The advertisement titled "Crush" has over a million views on Apple's YouTube channel




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Trump’s win sparks surprise rally in Indian IT stocks

Swiggy IPO sees slow start amid US election buzz




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Prices of flowers go up in the morning, stabilise and come down in the evening




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Public Information Officers sensitised to respond within time limit as per laws, says RTI Commissioner




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A slew of welfare schemes available for marginalised women, say Minister and officials at an outreach programme

200 beneficiaries selected by the Tamil Nadu Widows and Destitute Women Welfare Board will receive ₹50,000 each to establish self-employment ventures




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Google Pixel 9 Pro Fold Review | Blends software expertise with AI in a new form factor

The Pixel 9 Pro Fold not only marks Google’s foray into the foldable market in India, but also aims to redefine user expectations




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Shimron Hetmyer of Rajasthan Royals fined for breaching IPL Code of Conduct after losing to Sunrisers Hyderabad

IPL’s organisers did not specify why RR’s Shimron Hetmyer was fined; SRH won Qualifier 2 against RR by 36 runs yesterday




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IPL’s business value rises to $16.4 billion in 2024, CSK most valuable franchise

The report highlights the league’s global appeal, strategic initiatives, and engagement with fans




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MPL parent M-League’s revenue rises 22% to $130 million in FY24

Gaming company also recorded FY24 adjusted EBITDA of $0.2 million




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Accessorise your garden

Plant coriander in your shoe, hang a fern from your window, throw in a duck or two, and there’s your unique green space.




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Recognise the water warriors

Many groups have been working for water access to all as a human right, especially for the poor




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Is high-rise a solution?

Are high-rise residential blocks really eco-friendly as they claim? How do they fare in comparison to low-rise houses? By SATHYA PRAKASH VARANASHI