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The quasi-irreversible inactivation of cytochrome P450 enzymes by paroxetine: a computational approach

Org. Biomol. Chem., 2020, 18,3334-3345
DOI: 10.1039/D0OB00529K, Paper
Emadeldin M. Kamel, Al Mokhtar Lamsabhi
The potency of paroxetine as a P450 inhibitor is mainly attributed to the availability of two active sites on its structure, its compatibility with P450's active site and the ease of its tight coordination to heme iron.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A domino annulation approach to 3,4-diacylpyrrolo[1,2-a]pyrazines: decoration of pyrazine units

Org. Biomol. Chem., 2020, 18,3324-3333
DOI: 10.1039/D0OB00444H, Paper
Anuradha Dagar, Yohan Seo, Wan Namkung, Ikyon Kim
A new one-pot, sequential three-component access to 3,4-diacylpyrrolo[1,2-a]pyrazine was achieved from the reaction of an α-haloketone, azide, and N-substituted pyrrole-2-carboxaldehyde under mild reaction conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A base-promoted tandem approach to bicyclic 8-membered ring ketones

Org. Biomol. Chem., 2020, 18,3249-3253
DOI: 10.1039/D0OB00618A, Communication
Emerson E. F. dos Santos, Gabriela F. P. de Souza, Deborah A. Simoni, Airton G. Salles
A base-promoted tandem route toward unprecedented bicyclic furan/8-membered ring ketones is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Dipyrazolodioxadiazocines as shelf-stable “ready-to-use” precursors for an in situ generation of enolate-iminium 1,4-dipoles: a straightforward atom-economical approach to pyrazolo[5,1-d][1,3,5]dioxazines

Org. Biomol. Chem., 2020, 18,3382-3391
DOI: 10.1039/D0OB00451K, Paper
Vladimir E. Zhulanov, Valeria A. Vigovskaya, Maksim V. Dmitriev, Pavel S. Silaichev, Andrey N. Maslivets, Michael Rubin
Generation of cyclic enolate-iminium 1,4-dipoles via thermolysis of dipyrazolodioxadiazocines in the presence of ketones allowed for efficient preparation of pyrazolo[5,1-d][1,3,5]dioxazines.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Late-stage synthesis and application of photoreactive probes derived from direct benzoylation of heteroaromatic C–H bonds

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00336K, Communication
Kevin D. Hesp, Jun Xiao, Graham M. West
A synthetically-driven, late-stage C–H benzoylation strategy for the expedited preparation and evaluation of heterocyclic alternatives to more classical benzophenone photoreactive probes is reported.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Spiroconyone A, a new phytosterol with a spiro [5,6] ring system from Conyza japonica

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00666A, Paper
Long-Gao Xiao, Yu Zhang, Hong-Li Zhang, Ding Li, Qiong Gu, Gui-Hua Tang, Qian Yu, Lin-Kun An
The first rearranged phytosterol (spiroconyone A) with an unusual spiro [5,6] ring system and two new TDP1 inhibitors 7 and 10 showing a strong synergistic effect with topotecan were isolated from Conyza japonica.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fire arm, opening an eatery: get licence application forms online

Now, getting a licence for a fire-arm or operating an eatery will be easy with Delhi Police on Tuesday launching a dedicated website for its Licencing Branch.




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A strong and vibrant India is important for peace and stability in Asia: K Shanmugam, Singapore's foreign minister

Singapore is one of India's closest partners in Asia. In his first visit to meet PM Narendra Modi after the formation of the NDA government, K Shanmugam, Singapore's foreign minister, tells Indrani Bagchi they would build some of India's new smart cities and involve themselves in skill development programmes in India.




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Singapore appoints Sikh as Army chief

Singapore has appointed Brigadier General Ravinder Singh as its next army chief, the first Sikh in nearly 30 years to be given the force's baton.




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Indian girl raped, murdered and stuffed inside suitcase in Australia

24-year-old Tosha Thakkar was last seen alive on March 9 in Sydney. Her alleged attacker, Daniel Stani-Reginald, has been denied bail.




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Indians safe in Japan, some 30-40 Indians leave for India

The Indians, who were safely brought to a hotel in Tokyo from various rehabilitation centres in Sendai, have left for India.




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Indian dentists caught in UK red tape

Several dentists from India and other non-EU countries have been caught in bureaucratic wrangles between professional governing bodies in Britain, a leading migrants campaign group said today.




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Indians in Singapore produce movie

A group of Indian professionals in Singapore has produced a film, 'Mausams', which captures the tensed personal moments and challenges of working a city.




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Indian teachers in demand in Singapore

Indian teachers are most sought after in Singapore schools with increasing number of teachers being recruited to teach not only Indian languages but also other subjects.




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Yogi launches app to collect data of migrants




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Delhi construction workers told to use Aarogya app

Amid the debate over privacy concerns, Delhi government has issued orders to make Aarogya Setu mobile application popular among factory and construction workers returning to work after six weeks of lockdown.




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Delhi traders appeal for passes to check stock

Traders in commercial markets and shopping complexes have requested the government to issue passes so that they can open their shops for two-three days and check their stock.




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Coronavirus Pandemic: WhatsApp limits forwarding to one chat at a time to curb fake news

WhatsApp is also working directly with NGOs and governments, including the WHO and over 20 national health ministries, to help connect people with accurate information.




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Fact Check: Fake news regarding WhatsApp ticks, govt action on messages being circulated

The fake message was fact-checked by the PIB which said in a tweet that the "Government is doing no such thing."




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Google and Apple partner up to defeat COVID-19 outbreak, tech giants to jointly develop technology for contact tracing

The multinational companies, which hold the largest market shares in the sphere of technology, have decided to put their joint efforts in developing technology that will help world governments to cut the spread of the virus and save lives




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Apple announces new iPhone SE 2020, to come with minimum 64 GB storage

It has the same iPhone 8 design, but the camera and processor are new.




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USGS releases first comprehensive geological map of moon using Apollo data

The new map explains the 4.5-billion-year-old history of our neighbour in space.




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NASA's Hubble captures breakup of comet ATLAS into more than two dozen pieces

Hubble identified about 30 fragments on April 20, and 25 pieces on April 23.




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WhatsApp may soon allow you to use it on multiple devices simultaneously

The feature been under testing for some time.









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'Never thought of him as Sunny Deol; he's always Papa'

'Since my dad is the director and producer of the film, the environment at home is quiet, nervous, excited and honestly, I just want it over with. Then I can relax and move on with my life.'





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'Only Arjun Kapoor could play this role'

'Kriti Sanon is a superb actress, she looks Maharashtrian, and has not done a historical either.''Sanjay Dutt has gone to another level of persona. He hasn't done a historical either.'





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Is it okay to slap a woman?

'I know rapes haven't stopped after PINK, but now the topic of 'No means No' has become a table discussion at every home. And this is a big thing.''Thappad will at least start a discussion.'




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Irrfan: 'I'm happy to be back'

'The past two years have been dramatic, rather then traumatic.''I had bigger challenges that I have ever faced.'





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[ASAP] Modifying the Electrocatalyst–Ionomer Interface via Sulfonated Poly(ionic liquid) Block Copolymers to Enable High-Performance Polymer Electrolyte Fuel Cells

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00532




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[ASAP] Controlling Surface Phase Transition and Chemical Reactivity of O3-Layered Metal Oxide Cathodes for High-Performance Na-Ion Batteries

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00700




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[ASAP] A Self-Mediating Redox Flow Battery: High-Capacity Polychalcogenide-Based Redox Flow Battery Mediated by Inherently Present Redox Shuttles

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00611




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[ASAP] Highly Air-Stable Tin-Based Perovskite Solar Cells through Grain-Surface Protection by Gallic Acid

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00526




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[ASAP] Effect of Chelation on Iron–Chromium Redox Flow Batteries

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00761




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[ASAP] Detecting the Onset of Lithium Plating and Monitoring Fast Charging Performance with Voltage Relaxation

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00831




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[ASAP] An Extremely Fast Charging Li<sub>3</sub>V<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub> Cathode at a 4.8 V Cutoff Voltage for Li-Ion Batteries

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00702




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[ASAP] Toward Efficient Triple-Junction Polymer Solar Cells through Rational Selection of Middle Cells

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00857




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Novel fabric adapts to keeps you comfortable in all weathers

When conditions are warm and moist, such as those near a sweating body, the fabric allows heat to pass through. When conditions become cooler and drier, the fabric reduces the heat that escapes, researchers said.




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Self-consolidating concrete: applying what we know / Joseph A. Daczko

Barker Library - TA442.5.D33 2012




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A fracture approach for FRP-concrete structures 2012: held at the ACI 2012 Spring Convention ACI SP 286, Dallas, Texas, USA, 18-22 March 2012 / editors: Maria Lopez, Christian Carloni

Barker Library - TA444.F73 2012




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Bio-aggregate-based building materials: applications to hemp concretes / edited by Sofiane Amziane, Laurent Arnaud

Barker Library - TA441.B56 2013




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Understanding the tensile properties of concrete / edited by Jaap Weerheijm

Barker Library - TA440.U534 2013




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Progress in polymers in concrete: selected, peer reviewed papers from the 14th International Congress on Polymers in Concrete (ICPIC 2013), April 17-20, 2013, Shanghai, China / edited by Ru Wang and Zhenghong Yang

Barker Library - TA443.P58 I57 2013