cat Some guy complained this fishing game only caters to queer players, so the dev added a "straight" title - it costs $9999 By www.rockpapershotgun.com Published On :: Thu, 07 Nov 2024 15:36:16 +0000 When multiplayer fishing game Webfishing came out last month, it offered a relaxing hangout zone for cats and dogs. Everything revolves around catching, selling, and collecting the fish that gather in the rivers of a small island. It also lets you customise your character with clothing. Mostly simple hats and shorts, but some options let players celebrate their sexuality, such as a rainbow-adorned t-shirts, or titles that hang above your character which simply say "Trans" or "Bi". All this led one player to complain there was no "Straight" title. So, the developer added one. It costs 10 grand. Read more Full Article lamedeveloper Indie Sports PC Social Sandbox Webfishing
cat VED: Purification is a free prologue to the full hand-drawn RPG, complete with Stetson hats and Evil Dead trees By www.rockpapershotgun.com Published On :: Thu, 07 Nov 2024 15:47:45 +0000 Got an email about this. Looks cool. Is free. “I’ll write about that,” I thought. “I’ll write about that for Rock Paper Shotgun, a place that semi-regularly posts articles about cool and free games.” So here we are. If you’re waiting for the other shoe to drop, assuming the only reason I’d open an article in a superfluous and straightforward manner is because I’m about to deliver some sort of third sentence twist, you’re completely wrong! There’s no twist at all. I’m simply going to deliver some information about the game in a neutral tone. You can find VED: Purification, a free prologue demo to RPG VED, here. Read more Full Article RPG PC Free games VED: Purification
cat Escaping Harvey Weinstein was a ‘cat-and-mouse game,’ says Katherine Kendall By www.pbs.org Published On :: Wed, 18 Oct 2017 22:15:13 +0000 Watch Video | Listen to the AudioHARI SREENIVASAN: Let’s turn to the continuing fallout and reaction to the Harvey Weinstein story. Yesterday, Weinstein resigned from the board of his production company following numerous revelations of sexual harassment and several allegations of assault. More than three dozen women have said Weinstein harassed them. While Weinstein has admitted to behaving inappropriately, he has said he didn’t physically assault anyone. One of those women is Katherine Kendall. She was a 23-year-old actress who met Weinstein in 1993. She alleges that he invited her to his apartment in New York, where, she says, he took off his clothes and asked for a massage. As other actresses began coming forward about their painful experiences, she also went public with her own story. She joins me now from Los Angeles. First, thanks for joining us. And I don’t want to relive something that’s painful for you, but you are taking a public stance on it. For people who don’t know your story, what happened? KATHERINE KENDALL, Actress/ Photographer: Well, I was you know, a young actress, and I had had a formal meeting at the Miramax office earlier that day. And then, at the end of the meeting, which I thought went really well, he invited me to come to screenings. He said: “Welcome to the Miramax family. You know, come to premieres, screenings, et cetera. In fact, there’s one this afternoon. Would you like to come?” And I said, “Sure.” And I ended up going to see a movie with him. It ended up just being a movie, not a screening, but the film “Red Rock West.” And, you know, that’s right when I had this sort of sinking feeling that something wasn’t going right. And then, after the movie, we walked for a few blocks. And he said he needed to go up to his apartment to get something, and would I just come with him real quick? And I sort of said no, and we went back and forth on that for a minute. It was sort of a negotiation with him always, trying to sort of stand my ground, but then be convinced it was OK. I did go into his apartment. Once there, we talked for a long time about art and movies. And I felt like he was treating me like an intellect. And I felt like the meeting was going really well, and sort of continued. I didn’t feel unsafe once I was in there. And, at one point, then, he got up to go to the bathroom. And he came back in a robe and asked me to give him a massage. And I was extremely uncomfortable. And I was like, oh, God, no, I’m not comfortable with that. And we went back and forth on that. And then he went back to the bathroom again, and came back this time completely naked. And, you know, that changed it entirely for me, too. It just took it to the next place. It was completely disorienting. And I was scared, you know? I was really scared. And then it became sort of a cat-and-mouse game of, like, how am I going to get out of there? And I’m — it’s hard to make sense of what someone is trying to do to you when they’re fully naked, and they’re… HARI SREENIVASAN: Yes. KATHERINE KENDALL: You know, I’m 105 pounds. He’s a large man standing between me and the door. And, I mean, I felt very resolute, like, I will definitely get out of here somehow. But I’m not — I’m not sure — I’m not sure what’s going to happen here. You know, a lot was going through my head. And he said, well, if you won’t give me a massage, will you at least show me your breasts? And it was just — you know, it was, all in all, an extremely humiliating experience for me. And even though I got away, I felt like something had still — like something horrible had just happened to me. HARI SREENIVASAN: You know, in the immediate aftermath, did you tell someone about it? Because you have said before that you felt ashamed… KATHERINE KENDALL: I did. HARI SREENIVASAN: … even though you were the victim. KATHERINE KENDALL: I did. It’s really interesting how that happens. And I think — you know, I’m older now, and I have done some work on myself. And I have learned that a lot of people feel that way. It’s — it’s not — it wasn’t just me. But the just me feeling that this is my fault, this must have only happened to me, there’s something wrong with me, is so common when someone perpetrates against you. HARI SREENIVASAN: What were the… KATHERINE KENDALL: And I did. I told my mom. And I told some good friends. But, you know, one of the things that happened was, I didn’t want them to tell anybody. You know, people wanted to help me, but they didn’t know how, and I didn’t want them to try too hard, because I didn’t want it to backlash. I was scared. And I think that it’s important to remember that we don’t really come from a culture that supports women in talking about sexual harassment, in my — in my experience, that is. And, you know, I just haven’t felt like it was something I was going to get support on… HARI SREENIVASAN: You know, how long… KATHERINE KENDALL: … in the bigger picture. HARI SREENIVASAN: Yes. How long did this feeling last? Or, I guess, what are the longer-term ripple effects here? Did it shake your confidence in your abilities? KATHERINE KENDALL: I think it did. I think it did. I think it did. I think it made me feel like, wow, you know, that was a wash. He wasn’t interested at all in what I had to say, or, you know, he didn’t see any talent there or intellect there. He was assessing the situation the whole time for something else. And I think that — that did hurt. You know, I wish it didn’t. HARI SREENIVASAN: Yes. KATHERINE KENDALL: But he had produced so many movies that I thought were wonderful. And it was — it’s hard when someone has made art that you love, and how do you stay attached to liking their art, but feeling conflicted about them? And, yes, I think it does have long-term effects. I think you tuck it away. And then, for me, also, I realized that it came back when I would see his name or see him in person. I would start to sort of tremble all over again. I mean, I wouldn’t think about him on a daily basis or anything for years, and then I would see him, and I would think, oh, I don’t feel well. I got to get out of here. HARI SREENIVASAN: Right. KATHERINE KENDALL: You know, it would bring up so much emotion. And the most recent one was the woman in New York, the Italian model. I felt so, so enraged when I saw what happened there, and that they sort of — the police had him, and that then he got away. And then she was being dragged through the press as somebody who just, you know, wanted a payout, et cetera. HARI SREENIVASAN: You know, in the wake of that, there was — a friend of yours had tweeted, “At some point, all the women who have been afraid to speak out about Harvey Weinstein are going to have to hold hands and jump.” This was back in 2015. And from your Twitter account, you said, “Agreed.” It seemed like you almost had the opportunity to come forward. What made you want to come forward now? Has this become a turning point in the industry? KATHERINE KENDALL: This is a turning point. It’s a turning point. There are so many times when I thought about it, and then felt like — there were times when I thought about it and said, well, I have nothing to lose, I will just do it. And then I thought, I — I just didn’t have the strength or the courage yet. And I think somebody like Jodi Kantor doing the story for The New York Times, the fact that she thought it was a story at all was startling to me and made me feel like, wow, something is going to be done. And I knew she had told me — I mean, they were looking for women that this had happened to, because they’d been hearing rumors for so long that it happened to so many people. And she had told me other people were coming out. And I thought, I can’t — when I watched Rose McGowan or any of the other actresses come forward, I just — or Ashley Judd — I just thought, they look strong to me, and I don’t want to be the one that stays silent. HARI SREENIVASAN: Well, Katherine Kendall… KATHERINE KENDALL: I want to stand beside them. HARI SREENIVASAN: Katherine Kendall, thank you very much for speaking with us. And, hopefully, there are other people that are empowered by you coming forward. KATHERINE KENDALL: I hope so. Thank you. The post Escaping Harvey Weinstein was a ‘cat-and-mouse game,’ says Katherine Kendall appeared first on PBS NewsHour. Full Article harvey weinstein hollywood Katherine Kendall sexual harrasment
cat How Star Trek-style replicators could lead to a food revolution By www.newscientist.com Published On :: Wed, 11 Sep 2024 19:00:00 +0100 Our Future Chronicles column explores an imagined history of inventions and developments yet to come. This time, Rowan Hooper takes us to the early 2030s, when a technological step change enabled us to produce all the food we needed without the use of animals Full Article
cat Are we really ready for genuine communication with animals through AI? By www.newscientist.com Published On :: Wed, 30 Oct 2024 18:00:00 +0000 Thanks to artificial intelligence, understanding animals may be closer than we think. But we may not like what they are going to tell us, says RSPCA chief executive Chris Sherwood Full Article
cat House Republicans demand Biden Cabinet members preserve all documents, communications By www.washingtontimes.com Published On :: Tue, 12 Nov 2024 16:35:23 -0500 House Republicans on Tuesday demanded that each member of President Biden's cabinet preserve all relevant documents and communications, a move that signals future investigations into the Biden administration. Full Article
cat British Athletics want 'open' category for transgender women to compete with men By www.telegraph.co.uk Published On :: Fri, 03 Feb 2023 14:09:41 GMT Full Article topics:organisations/uk-athletics structure:sport storytype:standard
cat Is the BlackCat/AlphV ransomware gang self-destructing? By www.itbusiness.ca Published On :: Tue, 05 Mar 2024 01:36:27 +0000 The ongoing saga of the BlackCat/AlphV ransomware gang continues, with a news report that the crew has shut down its servers after a controversial hack of an American healthcare services provider. Bleeping Computer says the gang’s data leak blog shut on Friday and the sites it uses to negotiate ransom payments closed today. This comes […] The post Is the BlackCat/AlphV ransomware gang self-destructing? first appeared on ITBusiness.ca. Full Article Security alphv blackcat ransomware security strategies Top Story
cat How a new kind of vaccine could lead to the eradication of Alzheimer’s By www.newscientist.com Published On :: Tue, 27 Aug 2024 17:00:00 +0100 Promising new vaccines are designed to be given to patients at risk of developing Alzheimer's disease. If they perform well in clinical trials, they have the potential to one day rid society of dementia Full Article
cat We will one day be able to slow, halt and even eradicate Alzheimer's By www.newscientist.com Published On :: Wed, 28 Aug 2024 19:00:00 +0100 Despite the limitations of Alzheimer's drugs like lecanemab, this new class of treatments and a group of experimental vaccines are paving the way to a world without dementia Full Article
cat The complicated role loneliness plays in 26 common health conditions By www.newscientist.com Published On :: Mon, 16 Sep 2024 17:00:05 +0100 Loneliness was long thought to cause health conditions ranging from diabetes to cardiovascular disease, but new research paints a more nuanced picture Full Article
cat Children with cancer may benefit from having a cat or dog 'pen pal' By www.newscientist.com Published On :: Mon, 23 Sep 2024 19:00:32 +0100 Interacting with animals seems to provide emotional support to young people with a serious illness, even when the contact is via letters and not face to face Full Article
cat Betsy DeVos joins Trump’s call to 'disband' the Department of Education and 're-empower' families By www.foxnews.com Published On :: Tue, 12 Nov 2024 20:40:40 -0500 Former Education Secretary Betsy DeVos discusses what a second Trump term could mean for U.S. education on "The Story with Martha MacCallum." Full Article 2426f898-56cb-51b3-9650-47f0ef4cf50e fnc Fox News fox-news/media fox-news/topic/fox-news-flash fox-news/us/education/dept-of-education fox-news/politics/elections/presidential/trump-transition fox-news/shows/v-full-ep-the-story fox-news/media article
cat Comment on Case Study: Premature Baby Overcomes Life-Threatening Complications by Blue Techker By www.thehealthsite.com Published On :: Thu, 07 Nov 2024 14:49:56 +0000 <a href="https://bluetechker.com/" rel="nofollow ugc">Blue Techker</a> Nice post. I learn something totally new and challenging on websites Full Article
cat Comment on Numbness In The Arm, Face, And Leg Could Indicate A Stroke: Warning Signs To Watch Out For by 먹튀검증사이트 By www.thehealthsite.com Published On :: Mon, 11 Nov 2024 01:11:08 +0000 <a href="https://offhd.com/" rel="nofollow ugc">먹튀검증커뮤니티</a> 전문가들이 꼼꼼하게 검증한 안전한 토토사이트를 소개합니다. 안심하고 베팅하세요. 먹튀오프: https://offhd.com/ Full Article
cat Dem Rep. Torres: Biden Showed 'Incompetence' on Immigration Because He Catered to 'Far-Left Elites' By www.breitbart.com Published On :: Wed, 13 Nov 2024 02:59:00 +0000 On Tuesday’s broadcast of MSNBC’s “Morning Joe,” Rep. Ritchie Torres (D-NY) stated that “the Biden administration demonstrated incompetence in managing the migrant crisis,” President Joe Biden “had the unilateral ability to issue an executive order restricting migration at the border, and he waited two-and-a-half years,” because the order “was unpopular among far-left elites who have outsized power over the policymaking and messaging of the Democratic Party.” Torres said, “[O]n the subject of immigration, there was genuine political malpractice. Since 2022, there has been an unprecedented wave of migration, whose impact was felt, not only at the border, but in cities like New York, where the shelter system and our municipal finances were completely overwhelmed. … Despite clear signs of popular discontent, it took the Biden administration two-and-a-half years to issue an executive order restricting migration at the border, and by then it was too late. The Republicans had won the issue, had weaponized it against us. And when the President issued the executive order, polling revealed that it was popular among the American people, among people from every racial category, blacks and whites, Latinos and Asians. So, if it was effective at reducing migration at the border and if it was The post Dem Rep. Torres: Biden Showed ‘Incompetence’ on Immigration Because He Catered to ‘Far-Left Elites’ appeared first on Breitbart. Full Article Clips Immigration Politics border Joe Biden Ritchie Torres
cat Rays' Wander Franco charged with illegally carrying a gun in the altercation that led to his arrest By www.cbc.ca Published On :: Mon, 11 Nov 2024 12:43:50 EST Tampa Bay Rays shortstop Wander Franco was charged with illegally carrying a gun in his vehicle during the altercation in a parking lot that led to his arrest in the Dominican Republic over the weekend, prosecutors said Tuesday. Full Article Sports/Baseball/MLB
cat Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More By toucharcade.com Published On :: Thu, 22 Aug 2024 08:09:15 +0000 Following yesterday’s big Disney Dreamlight Valley update on Apple Arcade and other platforms, a few more notable games on Apple’s … Continue reading "Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More" Full Article Apple Arcade Featured Games iPad Games iPhone games News Universal
cat Out Now: ‘Punch Club 2: Fast Forward’, ‘Labyrinth: The Wizard’s Cat’, ‘TENSEI’, ‘Vampire: The Masquerade – Shadows of New York’, ‘Auto Pirates: Captains Cup’, ‘Jenny LeClue – Detectivu’ and More By toucharcade.com Published On :: Thu, 22 Aug 2024 18:18:17 +0000 Each and every day new mobile games are hitting the App Store, and so each week we put together a … Continue reading "Out Now: ‘Punch Club 2: Fast Forward’, ‘Labyrinth: The Wizard’s Cat’, ‘TENSEI’, ‘Vampire: The Masquerade – Shadows of New York’, ‘Auto Pirates: Captains Cup’, ‘Jenny LeClue – Detectivu’ and More" Full Article Featured News
cat TouchArcade Game of the Week: ‘Labyrinth: The Wizard’s Cat’ By toucharcade.com Published On :: Sat, 24 Aug 2024 01:42:57 +0000 I’m a simple man. Give me an old-school first-person dungeon crawler and I’m a pretty happy guy. Make one centered … Continue reading "TouchArcade Game of the Week: ‘Labyrinth: The Wizard’s Cat’" Full Article Featured Game of the Week News
cat Young relying on porn for 'sex education'... By www.news.com.au Published On :: 2024-11-13T06:19:36Z Young relying on porn for 'sex education'... (First column, 16th story, link) Full Article
cat Innovation Works opens grant application for hardware startups By www.bizjournals.com Published On :: Tue, 12 Nov 2024 22:52:28 +0000 The grant program provides hardware startups with reimbursement for working with local manufacturers. Full Article
cat Be Careful What You Say — Your Cat May Be Listening By www.discovermagazine.com Published On :: Mon, 11 Nov 2024 19:00:00 GMT Research suggests that cats can learn words, sometimes faster than a human baby. Full Article Planet Earth
cat What Education Looked Like for These 5 Ancient Societies By www.discovermagazine.com Published On :: Tue, 12 Nov 2024 16:00:00 GMT There is not a ton of evidence of what education looked like in ancient society, but we do know it existed - although not for everyone. Full Article The Sciences
cat Trump Faces Catch-22 in Manhattan Case By www.nationalreview.com Published On :: Tue, 12 Nov 2024 19:26:35 +0000 He has a good chance of getting the case reversed on appeal — but he can’t appeal until after Judge Merchan sentences him. Full Article
cat This Shin Megami Tensei board game features 72 intricate demon figurines By www.engadget.com Published On :: Mon, 11 Nov 2024 16:32:42 +0000 The popular Shin Megami Tensei video game series is getting a physical board game. A Japanese company called Icrea is behind the effort and is launching a Kickstarter on November 12 to raise funds for the project. SHIN MEGAMI TENSEI THE BOARD GAME (the company asked us to use all caps) is a “full-scale board game project” complete with 72 “high quality and detailed demon figures.” Collecting demons and adding them to your party is a major part of the game, so these figurines should help with immersion. It’ll also help with getting random demon figurines lost in the couch. Icrea/Atlus There’s a board with various locations from the franchise and plenty of series-specific cards to rifle through. The company says a game should take anywhere from three to four hours. The title has already generated a fair amount of excitement at both Gen Con and the most recent Tokyo Game Show. We don’t know exactly when this will be available for purchase. You know how Kickstarter timelines work. There are going to be a bunch of stretch goals, however, should the company reach the initial financial threshold. It’s a Shin Megami Tensei board game with dozens of cool-looking demon figurines. It shouldn’t have any trouble finding financial backers. For the uninitiated, Shin Megami Tensei first came out in 1992 for the Super Famicom in Japan. There have been plenty of sequels throughout the years. Shin Megami Tensei V came out back in 2021, but has since received a full-featured refresh called Shin Megami Tensei V: Vengeance. The Persona series is also a spinoff of the franchise. This leads to a very serious question. Persona board game when? I want to wander around a fake high school and eat ramen with a motley crew of characters.This article originally appeared on Engadget at https://www.engadget.com/gaming/this-shin-megami-tensei-board-game-features-72-intricate-demon-figurines-163242838.html?src=rss Full Article Video Games site|engadget provider_name|Engadget region|US language|en-US author_name|Lawrence Bonk
cat Channel 4 in the UK now has a dedicated app for Apple Vision Pro By www.engadget.com Published On :: Tue, 12 Nov 2024 20:00:28 +0000 The initial buzz for Apple’s mixed-reality headset has died down, but new apps and experiences are still arriving for consumers who plunked down $3,500. The UK broadcaster Channel 4 just dropped a dedicated streaming app for the headset, which lets users watch stuff in “ground-breaking cinema-style.” Channel 4 is the first UK broadcaster to take this step. The app leverages the tech inside the headset to overlay streaming content on the real world, which allows for a “full-screen viewing experience” of stuff like The Great British Bake Off and Taskmaster, in addition to multi-screen view. Speaking of Taskmaster, the broadcaster also announced an environment based on the comedy game show. Environments on the AVP transform the world around the user, so people can watch Taskmaster while sitting in a room inspired by Taskmaster (cue that Xzibit Yo Dawg meme.) Other streaming apps have their own environments. Paramount+ offers one based on SpongeBob Squarepants and Disney+ now includes one set in Iceland. This app doesn’t feature access to the recently-released Taskmaster VR experience. That one’s still tied to Steam VR and Meta Quest. By most accounts, it’s a pretty bad game, so the Vision Pro isn’t missing much.This article originally appeared on Engadget at https://www.engadget.com/ar-vr/channel-4-in-the-uk-now-has-a-dedicated-app-for-apple-vision-pro-200027166.html?src=rss Full Article Software Media Technology & Electronics Arts & Entertainment site|engadget provider_name|Engadget region|US language|en-US author_name|Lawrence Bonk
cat 27 000$ dérobés à Hydro-Québec: un avocat de Laval a volé de l’électricité pendant 14 ans By www.journaldemontreal.com Published On :: Tue, 12 Nov 2024 19:00:00 EST Un avocat de Laval épinglé pour son compteur d’Hydro-Québec trafiqué qui lui a fait économiser près de 27 000$ d’électricité devra payer une amende. Full Article
cat La caricature d’Ygreck en vidéo: Trump et Musk s'occuperont de la démocratie By www.journaldemontreal.com Published On :: Tue, 12 Nov 2024 11:30:00 EST Découvrez ci-dessous comment notre caricaturiste Ygreck a imagé son dessin. Full Article
cat Lockout at Port of Montreal could be 'catastrophic' for economy, port authority says By www.cbc.ca Published On :: Mon, 11 Nov 2024 08:48:11 EST A lockout at the Port of Montreal began Sunday night. The CEO of the Montreal Port Authority says if the dispute between dockworkers and the Maritime Employers Association drags on, it will have disastrous consequences for the economy. Full Article News/Canada/Montreal
cat Big picture show catches on By www.weeklytimesnow.com.au Published On :: Sun, 19 Jun 2016 14:00:00 GMT A RUSH is on to convert the nation’s mothballed wheat silos into the world’s biggest art gallery. Full Article
cat Polecats show no mercy to Beavers By www.dailytelegraph.com.au Published On :: Mon, 30 May 2016 05:27:00 GMT THE mercy rule was applied as table toppers Norwest Polecats posted a 54-4 victory over Cumberland Beavers in their NSW Tertiary Rugby League game at Kellyville on Saturday. Full Article
cat DoP rejects Aristo Pharma's review application for its multivitamin tablets By www.pharmabiz.com Published On :: Friday, November 8, 2024 08:00 IST The Department of Pharmaceuticals (DoP) has upheld the retail price fixation of National Pharmaceutical Pricing Authority (NPPA) for Mumbai─based Aristo Pharmaceuticals for its multivitamin tablets with Full Article
cat National online certificate course for pathologists on cervical cancer screening to begin from November 25 By www.pharmabiz.com Published On :: Saturday, November 9, 2024 08:00 IST The Indian Council of Medical Research─National Institute of Cancer Prevention and Research (ICMR─NICPR) is set to launch its first─ever DHR─funded National NICPR─ECHO online certificate course on cervical Full Article
cat Oversimplification about integration of traditional & modern treatment systems creates confusion: Dr Kotecha By www.pharmabiz.com Published On :: Tuesday, November 12, 2024 08:00 IST Oversimplification about integration of traditional and modern treatment systems often creates confusion among the stakeholders, and nobody understands the reality of the integration and what it is meant for, said Dr. Full Article
cat The role of surface preparation in the application of hydrophilic and hydrophobic coatings By www.medicalplasticsnews.com Published On :: Thu, 07 Nov 2024 16:30:00 -0000 Joe Anderson, product and promotional marketing manager at Harland, explores the role of surface preparation in the application of hydrophilic and hydrophobic coatings. Full Article
cat Catastrophic Floods in Spain Kill at Least 95 People By www.scientificamerican.com Published On :: Thu, 31 Oct 2024 16:00:00 +0000 Torrential rain, made worse by climate change, has lashed Spain, with Valencia bearing the brunt of the floodwaters Full Article
cat How the 2024 Election Could Change Access to Education in the U.S. and Influence Global Climate Change Decisions By www.scientificamerican.com Published On :: Mon, 04 Nov 2024 11:00:00 +0000 The outcome of the 2024 U.S. presidential election could set the climate agenda, reshape public education and shift the dynamics of global science collaboration. Full Article
cat FTC Revised Health Breach Notification Rule Goes into Effect By cohealthcom.org Published On :: Mon, 29 Jul 2024 14:43:12 +0000 Agencies with healthcare clients in pharmaceuticals, healthcare services, digital health apps, or health-related connected devices such as wearables should take note that the Federal Trade Commission (FTC) final rule updating its Health Breach Notification Rule (HBNR) that took effect on July 29, 2024. The FTC considers a breach to include a covered entity’s unauthorized disclosure […] Full Article Regulatory/FDA Federal Trade Commission final rule FTC Good Rx HBRN Jim Potter PHI privacy
cat NPRA Malaysia trials new timelines for variation applications By www.gabionline.net Published On :: Tue, 05 Nov 2024 09:13:55 +0000 <p>In May 2024, Malaysia’s National Pharmaceutical Regulatory Agency (NPRA) announced that it will trial new timelines for variation applications of registered pharmaceutical products and natural health supplements (TMHS).</p> Full Article
cat Government 'miscommunicated' PPE stock levels to pharmacies during first COVID-19 wave, MPs told By www.pharmaceutical-journal.com Published On :: Wed, 10 Feb 2021 12:17 GMT The government implied wholesalers had more personal protective equipment in stock than was the case during the first wave of the COVID-19 pandemic, the Healthcare Distribution Association has said. Full Article
cat NHS England lowers threshold for COVID-19 vaccination site applications By www.pharmaceutical-journal.com Published On :: Wed, 17 Feb 2021 12:13 GMT Community pharmacies able to administer up to 400 COVID-19 vaccines per week can now apply to become designated vaccination sites, NHS England has said. Full Article
cat These Words Have (Temporarily) Relocated By www.placebocontrol.com Published On :: Tue, 18 Mar 2014 14:17:00 +0000 Near the end of last year, I had the bright idea of starting a second blog, Placebo Lead-In, to capture a lot of smaller items that I found interesting but wasn't going to work up into a full-blown, 1000 word post. According to Murphy’s Law, or the Law of Unintended Consequences, or the Law of Biting Off More Than You Can Chew, or some such similar iron rule of the universe, what happened next should have been predictable. First, my team at CAHG Trials launched a new blog, First Patient In. FPI is dedicated to an open discussion of patient recruitment ideas, and I’m extremely proud of what we've published so far. Next, I was invited to be a guest blogger for the upcoming Partnerships in Clinical Trials Conference. Suddenly, I've gone from 1 blog to 4. And while my writing output appears to have increased, it definitely hasn't quadrupled. So this blog has been quiet for a bit too long as a result. The good news is that the situation is temporary - Partnerships will actually happen at the end of this month. (If you’re going: drop me a line and let’s meet. If you’re not: you really should come and join us!) My contributions to FPI will settle into a monthly post, as I have a fascinating and clever team to handle most of the content. In case you've missed it, then, here is a brief summary of my posts elsewhere over the past 2 months. First Patient In How to Catalyze a Clinical Trial - My inaugural post introducing the blog and its purpose Video: Predicting Referral Conversion in Clinical Trial Advertising - A somewhat technical but very important topic, how to visualize and model the “real time” results of recruitment advertising at the sites. The Crystal Ball is on the Fritz - What to do with a broken enrollment feasibility process, and how asking will never be as good as measuring Partnerships in Clinical Trials The New Breed of Clinical Trial Matchmakers - A (hopefully pretty complete, thanks to knowledgeable commenters) listing of services looking to match interested patients to clinical trials Rethinking Patient Enrollment, in One Graphic - The perils of predictability in site-based enrollment Seize the Data! Will Big Data Save Us from Ourselves? - My take on what I consider to be the large and serious obstacles in the way of “Big Data” solutions for patient recruitment Please take a look, and I will see you back here soon. [Photo credit: detour sign via Flikr user crossley] Full Article Big Data metrics patient engagement patient recruitment site relationship management
cat Cat's Eye Camera Can See Through Camouflage By spectrum.ieee.org Published On :: Thu, 19 Sep 2024 14:30:06 +0000 Did that rock move, or is it a squirrel crossing the road? Tracking objects that look a lot like their surroundings is a big problem for many autonomous vision systems. AI algorithms can solve this camouflage problem, but they take time and computing power. A new camera designed by researchers in South Korea provides a faster solution. The camera takes inspiration from the eyes of a cat, using two modifications that let it distinguish objects from their background, even at night. “In the future … a variety of intelligent robots will require the development of vision systems that are best suited for their specific visual tasks,” says Young Min Song, a professor of electrical engineering and computer science at Gwangju Institute of Science and Technology and one of the camera’s designers. Song’s recent research has been focused on using the “perfectly adapted” eyes of animals to enhance camera hardware, allowing for specialized cameras for different jobs. For example, fish eyes have wider fields of view as a consequence of their curved retinas. Cats may be common and easy to overlook, he says, but their eyes actually offer a lot of inspiration.This particular camera copied two adaptations from cats’ eyes: their vertical pupils and a reflective structure behind their retinas. Combined, these allowed the camera to be 10 percent more accurate at distinguishing camouflaged objects from their backgrounds and 52 percent more efficient at absorbing incoming light.Using a vertical pupil to narrow focus While conventional cameras can clearly see the foreground and background of an image, the slitted pupils of a cat focus directly on a target, preventing it from blending in with its surroundings. Kim et al./Science AdvancesIn conventional camera systems, when there is adequate light, the aperture—the camera’s version of a pupil—is small and circular. This structure allows for a large depth of field (the distance between the closest and farthest objects in focus), clearly seeing both the foreground and the background. By contrast, cat eyes narrow to a vertical pupil during the day. This shifts the focus to a target, distinguishing it more clearly from the background.The researchers 3D printed a vertical slit to use as an aperture for their camera. They tested the vertical slit using seven computer vision algorithms designed to track moving objects. The vertical slit increased contrast between a target object and its background, even if they were visually similar. It beat the conventional camera on five of the seven tests. For the two tests it performed worse than the conventional camera, the accuracies of the two cameras were within 10 percent of each other. Using a reflector to gather additional light Cats can see more clearly at night than conventional cameras due to reflectors in their eyes that bring extra light to their retinas.Kim et al./Science AdvancesCat eyes have an in-built reflector, called a tapetum lucidum, which sits behind the retina. It reflects light that passes through the retina back at it, so it can process both the incoming light and reflected light, giving felines superior night vision. You can see this biological adaptation yourself by looking at a cat’s eyes at night: they will glow.The researchers created an artificial version of this biological structure by placing a silver reflector under each photodiode in the camera. Photodiodes without a reflector generated current when more than 1.39 watts per square meter of light fell on them, while photodiodes with a reflector activated with 0.007 W/m2 of light. That means the photodiode could generate an image with about 1/200th the light. Each photodiode was placed above a reflector and joined by metal electrodes to create a curved image sensor.Kim et al./Science AdvancesTo decrease visual aberrations (imperfections in the way the lens of the camera focuses light), Song and his team opted to create a curved image sensor, like the back of the human eye. In such a setup, a standard image sensor chip won’t work, because it’s rigid and flat. Instead it often relies on many individual photodiodes arranged on a curved substrate. A common problem with such curved sensors is that they require ultrathin silicon photodiodes, which inherently absorb less light than a standard imager’s pixels. But reflectors behind each photodiode in the artificial cat’s eye compensated for this, enabling the researchers to create a curved imager without sacrificing light absorption. Together, vertical slits and reflectors led to a camera that could see more clearly in the dark and isn’t fooled by camouflage. “Applying these two characteristics to autonomous vehicles or intelligent robots could naturally improve their ability to see objects more clearly at night and to identify specific targets more accurately,” says Song. He foresees this camera being used for self-driving cars or drones in complex urban environments.Song’s lab is continuing to work on using biological solutions to solve artificial vision problems. Currently, they are developing devices that mimic how brains process images, hoping to one day combine them with their biologically-inspired cameras. The goal, says Song, is to “mimic the neural systems of nature.”Song and his colleague’s work was published this week in the journal Science Advances.This article appears in the November 2024 print issue. Full Article Image sensors Biomimicry Night vision Cameras
cat Medications for Opioid Use Disorder Improve Patient Outcomes By www.pewtrusts.org Published On :: Thu, 17 Dec 2020 12:43:00 -0500 In 2018, opioid overdoses in the United States caused one death every 11 minutes, resulting in nearly 47,000 fatalities. The most effective treatments for opioid use disorder (OUD) are three medications approved by the Food and Drug Administration (FDA): methadone, buprenorphine, and naltrexone. Full Article
cat En Banc: Federal Circuit Provides Guidance on Application of On-Sale Bar to Contract Manufacturers By www.lifescienceslawblog.com Published On :: Fri, 15 Jul 2016 16:04:54 +0000 Pharmaceutical and biotech companies breathed a sigh of relief Monday when the Federal Circuit unanimously ruled in a precedential opinion that the mere sale of manufacturing services to create embodiments of a patented product is not a “commercial sale” of the invention that triggers the on-sale bar of 35 U.S.C. § 102(b) (pre-AIA).[1] The en banc opinion...… Continue Reading Full Article Intellectual Property Ben Venue Laboratories CMO MedCo On-Sale Bar
cat Pain Management in Crisis: Why Hospitals Are Limiting Pain Medications and What This Means for Patients By worldofdtcmarketing.com Published On :: Fri, 01 Nov 2024 12:45:01 +0000 Hospitals across the U.S. have significantly restricted the use of pain medications containing narcotics. This shift comes amid […] The post Pain Management in Crisis: Why Hospitals Are Limiting Pain Medications and What This Means for Patients appeared first on World of DTC Marketing. Full Article Bad practices Focus on patients Pain Medication
cat Thai drama under fire for drugging cat for real in death scene, allegedly causing it seizures By www.asiaone.com Published On :: Tue, 12 Nov 2024 17:56:00 +0800 The quest for realism in Thai drama The Empress of Ayodhaya went too far when a cat was reportedly drugged in a poisoning scene. In episode five of the show, the character Indravedi (Fern Nopjira Lerkkajornnamkul) suspects her drink has been drugged, so she asks nanny Thongdee (Ja Molywon Phantara) to test it out on the black feline. The cat can be seen convulsing and retching, and the camera moves to show Indravedi looking concerned, while Thongdee declares that it is dead. The scene caused public outrage with fears that the cat had actually been killed, and calls to ban the period drama were trending on X. On Nov 7, a now-deleted X account reportedly belonging to Ja posted: "The cat didn't actually die. We put it under anaesthesia, but while filming, the cat retched and seized." She and Fern initially thought the cat had actually died while filming and their faces "turned pale", she added. Full Article
cat Education, Research, and Innovation in Africa: Forging Strategic Linkages for Economic Transformation By www.belfercenter.org Published On :: Feb 8, 2016 Feb 8, 2016 Africa is a youthful continent: nearly 41% of its population is under the age of 18. To address the unique challenges of this demographic structure, the African Union (AU) hopes to reposition the continent as a strategic player in the global economy through improved education and application of science and technology in development. The paper proposes the creation of “Innovation Universities” that combine research, teaching, community service and commercialization in their missions and operations. They would depart from the common practice where teaching is carried out in universities that do little research, and where research is done in national research institutes that do not undertake teaching. Under this model, there is little connection with productive sectors. The idea therefore is not just to create linkages between those activities but to pursue them in a coordinated way under the same university structure. Innovation universities can be created in diverse fields such as agriculture, health, industry, services, and environment to advance sustainable development and inclusive growth. Full Article