(University of Tsukuba) Researchers from the University of Tsukuba discovered that fish schools showed a significant change in behavior with varying school sizes. Using integrated information theory, they showed that a significant change in the interaction between the fish and the overall collective behavior occurred between three- and four-fish schools, including the emergence of leadership within the group. These findings help understand the dynamics of collective behavior.

Purpose: To determine the effect of smooth filter and partial volume correction (PVC) method on measured prostate-specific membrane antigen (PSMA) activity in small metastatic lesions and to determine the impact of these changes on the molecular imaging (mi) PSMA scoring. Materials & Methods: Men with biochemical recurrence of prostate cancer with negative CT and bone scintigraphy were referred for ¹⁸F-DCFPyL PET/CT. Examinations were performed on one of 2 PET/CT scanners (GE Discovery 610 or Siemens mCT40). All suspected tumor sites were manually contoured on co-registered CT and PET images, and each was assigned a miPSMA score as per the PROMISE criteria. The PVC factors were calculated for every lesion using the anatomical CT and then applied to the unsmoothed PET images. The miPSMA scores, with and without the corrections, were compared, and a simplified "rule of thumb" (RoT) correction factor (CF) was derived for lesions at various sizes (<4mm, 4-7mm, 7-9mm, 9-12mm). This was then applied to the original dataset and miPSMA scores obtained using the RoT CF were compared to those found using the actual corrections. Results: There were 75 men (median age, 69 years; median serum PSA of 3.69 ug/L) with 232 metastatic nodes < 12 mm in diameter (mean lesion volume of 313.5 ± 309.6 mm³). Mean SUV_max before and after correction was 11.0 ± 9.3 and 28.5 ± 22.8, respectively (p<0.00001). The mean CF for lesions <4mm (n = 22), 4-7mm (n = 140), 7-9mm (n = 50), 9-12 mm (n = 20) was 4 (range: 2.5-6.4), 2.8 (range: 1.6-4.9), 2.3 (range: 1.6-3.3) and 1.8 (range 1.4-2.4), respectively. Overall miPSMA scores were concordant between the corrected dataset and RoT in 205/232 lesions (88.4%). Conclusion: There is a significant effect of smooth filter and partial volume correction on measured PSMA activity in small nodal metastases, impacting the miPSMA score.

Lila Iké’s latest single, ‘ I Spy’, is flirty and playful with a sultry tone. It’s the kind of song record labels in decades past would compulsorily conflate with bubblegum pop princess images of lollipops, pigtails, ribbons, and skirts with...

BMJ Voices is a collection of readers’ experiences of working in the NHS. For this, The BMJ is seeking short audio submissions from UK listeners. These submissions will be published on thebmj.com. Patrick Keating, a GP from Enfield, is concerned that small practices are under pressure to increase list size, but aren't able to muster resources to...

For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give...

Colorado will no longer administer the full PARCC exam to students.

The Neyman-Pearson (NP) paradigm in binary classification seeks classifiers that achieve a minimal type II error while enforcing the prioritized type I error controlled under some user-specified level $alpha$. This paradigm serves naturally in applications such as severe disease diagnosis and spam detection, where people have clear priorities among the two error types. Recently, Tong, Feng, and Li (2018) proposed a nonparametric umbrella algorithm that adapts all scoring-type classification methods (e.g., logistic regression, support vector machines, random forest) to respect the given type I error (i.e., conditional probability of classifying a class $0$ observation as class $1$ under the 0-1 coding) upper bound $alpha$ with high probability, without specific distributional assumptions on the features and the responses. Universal the umbrella algorithm is, it demands an explicit minimum sample size requirement on class $0$, which is often the more scarce class, such as in rare disease diagnosis applications. In this work, we employ the parametric linear discriminant analysis (LDA) model and propose a new parametric thresholding algorithm, which does not need the minimum sample size requirements on class $0$ observations and thus is suitable for small sample applications such as rare disease diagnosis. Leveraging both the existing nonparametric and the newly proposed parametric thresholding rules, we propose four LDA-based NP classifiers, for both low- and high-dimensional settings. On the theoretical front, we prove NP oracle inequalities for one proposed classifier, where the rate for excess type II error benefits from the explicit parametric model assumption. Furthermore, as NP classifiers involve a sample splitting step of class $0$ observations, we construct a new adaptive sample splitting scheme that can be applied universally to NP classifiers, and this adaptive strategy reduces the type II error of these classifiers. The proposed NP classifiers are implemented in the R package nproc.

Si Cheng, Daniel J. Eck, Forrest W. Crawford.

Source: Statistics Surveys, Volume 14, 1--31.

Abstract:
A finite set is “hidden” if its elements are not directly enumerable or if its size cannot be ascertained via a deterministic query. In public health, epidemiology, demography, ecology and intelligence analysis, researchers have developed a wide variety of indirect statistical approaches, under different models for sampling and observation, for estimating the size of a hidden set. Some methods make use of random sampling with known or estimable sampling probabilities, and others make structural assumptions about relationships (e.g. ordering or network information) between the elements that comprise the hidden set. In this review, we describe models and methods for learning about the size of a hidden finite set, with special attention to asymptotic properties of estimators. We study the properties of these methods under two asymptotic regimes, “infill” in which the number of fixed-size samples increases, but the population size remains constant, and “outfill” in which the sample size and population size grow together. Statistical properties under these two regimes can be dramatically different.

Deep networks run with low precision operations at inference time offer power and space advantages over high precision alternatives, but need to overcome the challenge of maintaining high accuracy as precision decreases. Here, we present a method for training such networks, Learned Step Size Quantization, that achieves the highest accuracy to date on the ImageNet dataset when using models, from a variety of architectures, with weights and activations quantized to 2-, 3- or 4-bits of precision, and that can train 3-bit models that reach full precision baseline accuracy. Our approach builds upon existing methods for learning weights in quantized networks by improving how the quantizer itself is configured. Specifically, we introduce a novel means to estimate and scale the task loss gradient at each weight and activation layer's quantizer step size, such that it can be learned in conjunction with other network parameters. This approach works using different levels of precision as needed for a given system and requires only a simple modification of existing training code.

Catherine Mankiw
May 24, 2017; 37:5221-5231
Development Plasticity Repair

The cats also cross the road an average of 4.5 times in six days, putting themselves in danger

The findings further refute the outdated notion that humans' capacity for complex artistic expression evolved exclusively in Europe

SOLIDWORKS Image Quality settings have the biggest impact on file size and system performance. We always assumed that it would have an impact on overall performance also. The effect varies widely across different files, so we decided to do SOLIDWORKS

Author information

The post The Impact of Image Quality on SOLIDWORKS Performance and File Size appeared first on SOLIDWORKS Tech Blog.

New findings on a state initiative in Wisconsin suggest that to make the most out of smaller class sizes in the early grades, teachers should focus on basic skills when they have one-on-one contact with students, ask children to discuss and demonstrate what they know, and have a firm, but nurturing,

Gov. Jeb Bush has warned that Florida won't meet class-size limits without taking such steps as expanding private school vouchers, lifting restrictions on the number of charter schools, and moving to year-round schedules.

The proposed budget from the Trump administration eliminates the Title II grant program, which pays for professional development and class-size reduction efforts.

A majority of states have at least one policy that limits the number of students that may be in a general education classroom, according to the Education Commission of the States. Among states that have changed their class-size policies since 2008, all have opted to relax those constraints.

Renee Moore questions the wisdom of the the idea—raised in recent days by both Bill Gates and U.S. Secretary of Education Arne Duncan—of paying effective teachers more for taking on larger class sizes: Giving the most effective teachers larger classes is NOT a way to reward them, but it is a way to

In an opinion piece published by the The Atlanta Journal-Constitution Peter Smagorinsky, a professor of English education at the University of Georgia, questions the value of recent policy reports showing that increases in class sizes do not have a detrimental effect on student test scores. Most peo

Keeping preschool class sizes at or under 20 children, and keeping child-teacher ratios at 10 to 1, will work for most children in preschool, according to a new study.

In recent years, reducing class size has gained increased prominence as a school-improvement strategy. Some 40 states now have class-size-reduction initiatives in place, and federal money is available for such efforts as well. The teachers' unions, meanwhile, routinely tout class-size reduction as a

Class size does matter for teachers and students, but only if the instruction used in the small class size is different from those instructional practices used in a large one.

Only very large reductions in class size are likely to lead to significant long-term effects on student achievement, a new research synthesis says.

In recent years, reducing class size has gained increased prominence as a school-improvement strategy. Some 40 states now have class-size-reduction initiatives in place, and federal money is available for such efforts as well. The teachers' unions, meanwhile, routinely tout class-size reduction as a

The situation in the Clark County School District is a perfect storm that serves as a reminder of how difficult it is for school officials to plan for changing conditions

Continuing increases in K-12 enrollment, a downturn in higher education enrollment, and a rise in cyberbullying are among the trends illustrated in two new statistical publications from the U.S. Department of Education.

If class sizes aren't going to be addressed because of bottom lines, either because of a lack of teacher resources or school funding, then we are going to have to find a way to function better inside of these undesirable situations.

Size matters in nurturing the relationship between teachers and students.

Hundreds of teachers across the Sacramento Unified school district walked out of their classrooms and onto picket lines last week for the first time in 30 years, staging a one-day strike alleging unfair labor practices by the California district.

The newly formed group, which plans to challenge the Council for Accreditation of Educator Preparation for market share, wants feedback from the public on its proposed standards and processes.

Research has shown that dishware size influences self-served portion sizes and meal intake in adults. In children, larger bowls led children to request more food, but whether larger dishware affects children’s self-served portions or intake at meals is not known.

We assessed the effect of increasing dishware size on self-served portions and intake in young children. Larger plates and bowls resulted in larger self-served portions, and indirectly promoted greater intake, emphasizing the importance of age-appropriate dishware. (Read the full article)

Sibship size has been negatively associated with children’s language, cognitive, and academic outcomes. This phenomenon is often explained in terms of resource dilution, wherein more children in the home is associated with fewer parental resources allocated to each child.

The current study identifies a moderator of this relationship. Specifically, if children’s next-in-age older siblings exhibit high levels of cognitive sensitivity then sibship size is not significantly related to children’s vocabulary. (Read the full article)

The fetal origins of adult disease hypothesis proposes that suboptimal fetal development may condition the later risk of disease, particularly cardiovascular disease. However, this hypothesis has never been tested for diseases of the aging brain.

This first study of its kind provides clinical measures suggesting that small birth size, as an indicator of an adverse intrauterine environment, has lifelong consequences for brain tissue volume and cognitive function. In addition, it shows that the effects of a suboptimal intrauterine environment on late-life cognitive function were particularly present in those with lower educational levels. (Read the full article)

A majority of states have at least one policy that limits the number of students that may be in a general education classroom, according to the Education Commission of the States. Among states that have changed their class-size policies since 2008, all have opted to relax those constraints.

Students are learning how to research and write scripts, hone interviewing techniques, and edit video footage, and some teenagers are even earning certifications in media technology.

Former West Indies captain Brian Lara's cheeky dig at Suresh Raina left fans in splits on social media.

NASA's Near-Earth Object Studies Center has classified the asteroid 1998 OR2 as the 'potentially hazardous object' as it flies at regular intervals past Surface's earth. In particular, about 125 other objects were found to be potentially hazardous.

Greeting to all:

I am new in this tool, only 2 weeks. Trying to create a new Via with smaller size drill hole from exiting 13 mils size to 10 mils size. I got the message as imaged below. Any advise what to do?  Thanks in advance.

The way you need blocks of different sizes and styles to build great Lego masterpieces, a complex WSP-based design requires stitching together routing regions with multiple patterns that follow different WSSPDef periods. Let's see how you can achieve this. (read more)

A meeting of Group of Twenty energy ministers in Istanbul earlier this month affirmed a collective belief in renewable energy -- including hydroelectric power -- amongst the major economies that constitute the international forum.

Next-Generation Miniaturized Rubidium Atomic Clock Improves Performance and adds Features without Increasing Size

Microchip Expands Silicon Carbide (SiC) Family of Power Electronics to Provide System Level Improvements in Efficiency, Size and Reliability

Financial constraints are a significant barrier for India's SMEs participating in global value chains.

Export performance and firm size have a positive impact on trade participation at the intensive margin for firms of all sizes.