A single-chain, tailless Xenopus laevis H2A/H2B dimer construct (scH2BH2A) was engineered by directly fusing the C-terminus of H2B to the N-terminus of H2A without an artificial linker sequence. A high-resolution crystal structure of scH2BH2A shows that it adopts a nearly identical fold to that of nucleosomal H2A/H2B and may be useful for future structural studies of many H2A/H2B-interacting proteins.

On September 14, 2015, the Laser Interferometer Gravitational-wave Observatory (LIGO) detected gravitational waves from the merger of two black holes 29 and 36 times the […]

The post Ligo’s Twin Black Holes Might Have Been Born Inside a Single Star appeared first on Smithsonian Insider.

“Think of a lion shrunk to the size of a mouse that needs to eat every 20 minutes or so.” That is a shrew, says […]

The post New Costa Rican shrew species named from a single specimen found 44 years ago appeared first on Smithsonian Insider.

Single-wavelength X-ray anomalous diffraction (SAD) is a frequently employed technique to solve the phase problem in X-ray crystallography. The precision and accuracy of recovered anomalous differences are crucial for determining the correct phases. Continuous rotation (CR) and inverse-beam geometry (IBG) anomalous data collection methods have been performed on tetragonal lysozyme and monoclinic survivin crystals and analysis carried out of how correlated the pairs of Friedel's reflections are after scaling. A multivariate Bayesian model for estimating anomalous differences was tested, which takes into account the correlation between pairs of intensity observations and incorporates the a priori knowledge about the positivity of intensity. The CR and IBG data collection methods resulted in positive correlation between I(+) and I(−) observations, indicating that the anomalous difference dominates between these observations, rather than different levels of radiation damage. An alternative pairing method based on near simultaneously observed Bijvoet's pairs displayed lower correlation and it was unsuccessful for recovering useful anomalous differences when using the multivariate Bayesian model. In contrast, multivariate Bayesian treatment of Friedel's pairs improved the initial phasing of the two tested crystal systems and the two data collection methods.

The analytical solution of the problem of X-ray spherical-wave Laue diffraction in a single crystal with a linear change of thickness on the exit surface is derived. General equations are applied to a specific case of plane-wave Laue diffraction in a thick crystal under the conditions of the Borrmann effect.

No single approach -- technical, legal, economic, or educational -- will be sufficient to protect children from online pornography.

A single breakthrough discovery for managing citrus greening in Florida in the future is unlikely, says a new report by the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine offers guidance to the Consumer Product Safety Commission (CPSC) on how to conduct a hazard assessment of nonpolymeric, additive organohalogen flame retardants (OFRs), which are used in some consumer products.

The world's first full-scale artificial wetland designed to treat both sewage effluent and mine wastewater has been found to continuously remove high levels of pollutants, a recent study concludes. Treating both types of wastewater at the same time proved to be highly beneficial because they contain pollutants which are more easily removed when mixed together.

SASOL has adopted telepresence for collaboration between far-flung executives in Europe, North America and Africa. Running over the BT IP Connect global network it also enables federation with customers and suppliers. The solution’s earned Alec’s team a special recognition award from the CEO for bringing the company’s One SASOL philosophy and vision vibrantly to life

FREDERICKSBURG , Va. – An additional evening of work is required this week for an ongoing pin replacement on the Robert O. Norris Bridge, and...

FREDERICKSBURG , Va. – An additional evening of work is required this week for an ongoing pin replacement on the Robert O. Norris Bridge, and...

NOV. 12, 2018 UPDATE: All lanes of Route 3 over the Rappahannock River between Lancaster and Middlesex counties will remain open this evening, Nov....

Because there's no shame in being single on Valentine's Day.

Confirming a bit of conventional wisdom, a new study finds that people who fear being single often settle for less in love.

Jadav Payeng single-handedly turned a barren sandbar in northern India into a lush new forest ecosystem.

Drinking straws are one item that's days are numbered as Ikea vows to eliminate throwaway plastic products from its product range and in-store eateries.

Many countries, states and municipalities are getting serious about reducing the use of plastic bags, utensils and containers.

The dictionary's most popular word of the year has to do with waste.

Longtime eco-friendly coffee makers attempt a green solution to the waste of single servings.

Take a look at what the world's water supply would look like as a single drop - and find out what your family can do to protect it.

Forget the idea that only 10-minute bursts of activity are important. New research finds that even small moments of activity can help you meet your goal.

At a single Starbuck location, a whooping 378 people bought coffee for the person behind them.

Popular online shopping holiday produces billions of dollars in sales — and billions of boxes in the trash.

A 'living' wrapper called kombucha slime could ease the world's plastic pain.

No outlet needed for this lamp — just plug it into the nearest plant.

Whatever your intent, the statistics show you're probably only using those reusable bags once.

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Can there be one single cure for everyone or do acne cures exist only for the lucky few?

MeetNativeAmericans.com is a perfectly secure dating website that provides all singles with a unique chance to chat and bond with Native Americans.

BodybuilderSingles.com is new dating site devoted to the devotees of health and body-beautiful around the world. This new service allows bodybuilders and health enthusiasts to find each other online.

Artist & electronic music producer launches brand new inspirational-styled song

The sound of 'Indian Trap' is a blend of cultural roots of Punjabi, Bhangra and Bollywood music, infused with Hip-Hop and Trap elements.

Reality star Shawn Mr. Bigg Bullard is introducing his hot and eye catching new video "Zaddy" in conjunction with his viral "#Zaddy Challenge" on Valentine's Day with a grand prize to follow.

Soulfire Mix was produced by Dan Malsch and co-written by Cristyle.

From open concept single-story floor plans to spacious two-story flexibility that works for growing families, Cascade and Daybreak offer exceptional choices for first-time, move-up and move down buyers.

Silver Lining encourages strength when facing adversity and overcoming situations of despair - bullying, violence, abuse, trauma - reminding us to practice self love, patience, and acceptance over hate.

Company Launches Single-Sign-On (SSO)/Active Directory Integration for Cloud-Hosted Customers

The coveted, and sometimes elusive, single-story floor plan is alive and well at Pardee Homes' Cascade neighborhood in master-planned Sundance, where new home prices start in the low $300,000s.

Emmy Award Winning television company, Production Partners, Inc. and its new indie record label Cowboy Records, release new single, for singer/songwriter, Travis "Randall" Hughes, country folk song "It's On Me."

In celebration of Rapper Chef Seans new single release on July 30th, 2019 "No Name" through Sony/ The Orchard, a single release party will be held at The Pheonix in Beverly Hills, CA.