The deep penetrations suggest that the feline was pressing its claws into the clay, a behavior sometimes known as "making biscuits"

Born October 30 to parents Gloria and Otto at the Edinburgh Zoo in Scotland, the hippo is already gaining popularity, following in the footsteps of viral sensation Moo Deng

New Brunswick’s Court of Appeal has reserved judgment in the case of a man found guilty of criminal negligence in the death of Fredericton teenager in 2018.

This will be the first Remembrance Day celebrated at the new Royal Canadian Legion in Sault Ste. Marie. Branch 25 recently opened a new complex in the northern Ontario city, complete with a 108-unit apartment tower.

Details remain scarce surrounding the death of a Canada Border Services Agency (CBSA) officer at the Ambassador Bridge on Saturday. The border authority and union said an employee died by suicide while on the job on the Windsor, Ont., side of the border. 

Interactive 3D manuals increase customer appreciation and satisfaction

Here's a new angle on GDPR, likely one of many angles people haven't yet considered: Does web session recording count as collecting PII?

By aligning outreach efforts at the Positively Dover African American Festival, DPH and DST aim to improve health outcomes statewide. DOVER, DEL. (June 20, 2024) – The Delaware Division of Public Health (DPH) Cancer Prevention and Control (CPC) Bureau and the Community Health Mobile Unit are partnering with the Dover Alumnae Chapter of Delta Sigma […]

Google's Gmail update went live this week. Here's what marketers need to know

One of the wonderful aspects about my client-facing role at SAS is the breadth of audiences that I get to work with. No matter where you fall on this list: Data engineer. Business or marketing analyst. Citizen data scientist. Data scientist. Statistician. Executive. One topic is certain: We all love [...]

SAS Customer Intelligence 360: Automated explanation and supervised segmentation was published on Customer Intelligence Blog.

A remarkable result in probability theory is the "three-sigma rule," which is a generic name for theorems that bound the probability that a univariate random variable will appear near the center of its distribution. This article discusses the familiar three-sigma rule for the normal distribution, a less-familiar rule for unimodal [...]

The post The three-sigma rule appeared first on The DO Loop.

Sitaram Yechury, the fifth general secretary of the CPM, died on September 12, 2024, after a prolonged illness. He was admitted for days at Delhi's All-India Institute of Medical Sciences after he had contracted a lung infection.

In the era of Artificial Intelligence, front-end designers need a magical key to empower them with technology that enables fully optimized RTL for implementation handoff and provides RTL designers with capabilities to accurately assist in the implementation convergence process.

The magic lies with Cadence Joules RTL Design Studio, an expert system that leverages generative AI for RTL design exploration, triages possible causes of violations, and additional insights that empower designers to understand how to address issues in their RTL, leading to smarter and more efficient chip design.

This unlocks the immense debugging and design analysis capabilities from a single, unified cockpit, enabling fully optimized RTL design prior to implementation handoff for the front-end designers and addresses all aspects of physical design by adding visibility into power, performance, area, and congestion (PPAC)

One critical component is the clock tree, which distributes the clock signal to all sequential elements, such as flip-flops and latches. Designers need the right techniques in the beginning stage to optimize the clock tree structure, ensuring that their designs meet the required timing specifications, reduce power consumption, maintain signal integrity, and increase reliability.

 This incredible feature is part of the Joules RTL Design Studio.

How do you efficiently explore the clock tree structure to optimize the results using Joules RTL Design Studio?

Joules Studio allows viewing a simplified version of the clock structure. This feature is primarily designed to help display clock frequency scaling through clock dividers. You can customize colors, symbols, and design elements using an input file. Additionally, you can cross-probe the custom clock tree structure to other widgets and the main schematic view in Joules Studio.

Moreover, with the clock tree preference features of the ideal clock tree wizard in Joules Studio GUI, you can highlight clock path, generate clocks and master clock, set case analysis, fold and unfold instances, undo and redo, set sense and disable timing, color preference, etc.

You can binge on these features through the channel videos posted on the support portal, which covers the Joules RTL Design Studio GUI Clock Tree Structure and Features of Ideal Clock Tree Wizard.

You can refer to the videos on Cadence Online Support (Cadence login required).

​Video Links:
Viewing Custom Clock Tree Structure in Joules RTL Design Studio (Video) 

Exploring Clock Tree Preference Widget of Ideal Clock Tree Wizard in Joules RTL Design Studio (Video) 

Want to learn more?

Explore the one-stop solution Joules RTL Design Studio Product Page on Cadence Online Support (Cadence login required).

Related Resources 

Related Training Bytes:

Understanding Prototype Design Flow in Joules RTL Design Studio (Video)

Running Prototype Implementation Flow in Joules RTL Design Studio (Video)

Understanding Analyze Timing By Hierarchy In Joules RTL Design Studio (Video)

Related Courses:

• Joules Power Calculator

Want to Enroll in this Course?

We organize this training for you as a "Blended" or "Live" training. Please reach out to Cadence Training for further information.

Please don't forget to obtain your Digital Badge after completing the training.

Related Blogs:

Let's Discover the Secret to Enhance Design's PPAC in a Single Cockpit! - Digital Design - Cadence Blogs - Cadence Community

Joules RTL Design Studio: Accelerating Fully Optimized RTL - Digital Design - Cadence Blogs - Cadence Community

Let's Replay the Process of Power Estimation with the Power of 'x'! - Digital Design - Cadence Blogs - Cadence Community

Is Design Power Estimation Lowering Your Power? Delegate and Relax! - Digital Design - Cadence Blogs - Cadence Community

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.

This event is expected to draw around 25,000 attendees, leading to significant delays on key routes across the island

Information manipulation and misinformation are not new phenomena, but they have taken on exaggerated importance, especially with the massive use of social media. Hostile and stigmatizing narratives against civil society and civic activism, whether intentional or not, especially when propagated by authorities, create undue restrictions and hinder the exercise of the rights to freedom of […]

The project will reduce trans-boundary animal diseases (TAD), food safety and zoonotic disease risks and strengthen livestock value chains and COVID-19 responses through investments in infrastructure, capacity building and policy support. The project will have the following outcome: health, value chains, and formal trade of livestock and livestock products improved. The project will be aligned with the following impact: GMS vision as a leading supplier of safe and environmentally friendly agriculture products realized.

A 15-kilometre-long mass of lava has formed underneath the Reykjanes peninsula in Iceland and could erupt at any time

In Iceland, scientists are planning to drill two boreholes to a reservoir of liquid rock. One will give us our first direct measurements of magma – the other could supercharge geothermal power

As a 15-kilometre crack formed ahead of the recent eruptions, magma flowed into it at the highest rate observed anywhere in the world

Five years ago, a fossil found in the Philippines was determined to be from a new species of hominin called Homo luzonensis. Since then, we’ve learned a bit more about the newest member of the human family

Around 3000 years ago, several empires and kingdoms in the Mediterranean collapsed, with a group of sea-faring warriors implicated as the culprit. But new evidence shows that many of our ideas about this turbulent time need completely rethinking

Title: Eye Pigment May Help Vision in Hazy Conditions
Category: Health News
Created: 8/28/2014 9:35:00 AM
Last Editorial Review: 8/28/2014 12:00:00 AM

ABSTRACTWe document the effort over the last 30 years to respond to the call by women advocates at the International Conference on Population and Development for more woman-initiated single or dual-purpose contraceptive methods by developing the Caya contoured diaphragm, an innovative diaphragm designed to meet the needs of women and their partners and expand options for nonhormonal barrier contraception. We describe the complex and interrelated set of activities undertaken to develop the product using a human-centered design process and how we are working to create a corollary sustainable market. This review includes the evidence generated around improved acceptability among couples in low- and middle-income countries and depicts challenges and practical actions on how to dispel misconceptions about diaphragm use. Importantly, we share programmatic lessons learned on increasing universal access to this new sexual and reproductive health technology. Following our new model for increasing access to new and underutilized methods, Caya is now registered and being marketed in nearly 40 countries worldwide.

Previous studies demonstrated that sigma receptor (R) antagonists alone fail to alter cocaine self-administration despite blocking various other effects of cocaine. However, R antagonists when combined with dopamine transporter (DAT) inhibitors substantially decrease cocaine self-administration. To better understand the effects of this combination, the present study examined the effects of R antagonist and DAT inhibitor combinations in male rats discriminating cocaine (10 mg/kg, i.p.) from saline injections. The DAT inhibitors alone [(–)-2-β-carbomethoxy-3-β-(4-fluorophenyl)tropane 1,5-naphthalenedisulfonate monohydrate (WIN 35,428) and methylphenidate] at low (0.1-mg/kg) doses that were minimally active failed to shift the dose-effect function for discriminative-stimulus effects of cocaine to the left more than 2-fold. At 0.32 mg/kg the DAT inhibitors alone shifted the cocaine dose-effect function leftward 24- or 6.6-fold, respectively. The R antagonists (BD1008, BD1047, and BD1063) failed to fully substitute for cocaine, although BD1008 and BD1047 substituted partially. At 10 mg/kg, BD1008, BD1047, or BD1063 alone shifted the cocaine dose-effect function leftward less than 6.0-fold. In combination with 0.1 mg/kg WIN 35,428, the 10 mg/kg doses of R antagonists shifted the cocaine dose-effect function from 12.3- to 36.7-fold leftward, and with 0.32 mg/kg WIN 35,428 from 14.3- to 440-fold leftward. In combination with 0.1 mg/kg methylphenidate, those R antagonist doses shifted the cocaine dose-effect function from 5.5- to 55.0-fold leftward, and with 0.32 mg/kg methylphenidate from 10.5- to 48.1-fold leftward. The present results suggest that dual DAT/R inhibition produces agonist-like subjective effects that may promote decreases in self-administration obtained in previous studies.

BACKGROUND AND PURPOSE:

Percutaneous cement augmentation has been reported as an effective salvage procedure for frail patients with spinal instrumentation failure, such as screw loosening, hardware breakage, cage subsidence, and fractures within or adjacent to stabilized segments. Favorable results were reported during a median follow-up period of 16 months in a retrospective analysis of 31 consecutive procedures performed in 29 patients. In the present study, the long-term effectiveness of this treatment in avoiding or postponing revision surgery is reported.

Approximately 8.5%–16.2% of childhood cancers are associated with a pathogenic/likely pathogenic germline variant—a prevalence that is likely to rise with improvements in phenotype recognition, sequencing, and variant validation. One highly informative, classical hereditary cancer predisposition syndrome is Li–Fraumeni syndrome (LFS), associated with germline variants in the TP53 tumor suppressor gene, and a >90% cumulative lifetime cancer risk. In seeking to improve outcomes for young LFS patients, we must improve the specificity and sensitivity of existing cancer surveillance programs and explore how to complement early detection strategies with pharmacology-based risk-reduction interventions. Here, we describe novel precision screening technologies and clinical strategies for cancer risk reduction. In particular, we summarize the biomarkers for early diagnosis and risk stratification of LFS patients from birth, noninvasive and machine learning–based cancer screening, and drugs that have shown the potential to be repurposed for cancer prevention.

The inaugural Red Lorry Film Festival in 2024 saw over 100 international films across various categories and languages

Un défenseur bélarusse au potentiel incalculable réalise bien malgré lui les défis quotidiens qui accompagnent son physique hors-norme.

Sydney, Australia (SPX) Nov 04, 2024
In a recent study led by Professor Xin Li and Dr. Yanlong Guo of the Institute of Tibetan Plateau Research, Chinese Academy of Sciences, researchers analyze how scientific research is evolving through the power of big data and artificial intelligence (AI). The paper discusses how the traditional "correlation supersedes causation" model is being increasingly challenged by new "data-intensive scie

Dunia perjudian daring telah menyaksikan kemunculan penyedia perangkat lunak yang menghebohkan, dan di antara mereka, Pragmatic Play telah berhasil menarik perhatian para pemain dengan berbagai slot online unggulan. Dalam artikel…

The post Menjelajahi Dunia Keajaiban Slot Online Pragmatic Play appeared first on Biosimilarnews.

Jul 28, 2024

The Africa in Focus series is a forum for the intellectual and critical analysis of processes and policies from the continent and its engagement with the international community. Through thoughtful and dynamic programming, Africa in Focus brings greater African perspectives into broader policy conversations at HKS.

Stag�s Leap Wine Cellars celebrates the 40th anniversary of The Judgment of Paris, which helped to elevate the esteem of American wine worldwide

CCFA Partners is an innovative network where patients and researchers work together. Become a part of groundbreaking research: www.ccfapartners.org.

Studio based in Osaka, Tokyo to focus on AAA action games

Tolerability

While often perceived as a women's disease, breast cancer affects men as well. Stigma, however, can delay diagnosis and treatment, potentially worsening outcomes.

The medlinkLGBTQ/medlink individuals experience less stigma than anticipated, while people with mental health conditions continue to encounter greater

The Groundwater Management Information System (GMIS) can help in developing water policies and better water management practices.

The post IWMI tackles water scarcity in Punjab with groundbreaking GMIS first appeared on International Water Management Institute (IWMI).

Nearly 15.23 lakh people living with HIV are being provided with free antiretroviral (ARV) medicines through 687 ART centers and 1261 link ART centers

medlinkAugmented reality/medlink (AR) is poised to dramatically change healthcare, particularly in surgical procedures. By overlaying digital information

Pre-exposure prophylaxis (PrEP) reduces the risk of sexually transmitted HIV infection by up to 99%. The uptake of medlinkPrEP/medlink seems to be

Driving workforce participation, support for small businesses and much needed investment in infrastructure make this a pragmatic budget.

1. Swiggy Share Price Live Updates: Stock makes a positive debut, opens with 7.69% premium at ₹420 on NSE; check GMP | Stock Market News  Mint
2. Swiggy shares list at 8% premium over IPO price  The Economic Times
3. ‘You and I…’: Zomato welcomes Swiggy on Dalal Street after stock market listing  India Today
4. Swiggy’s reclusive CEO Sriharsha Majety makes rare public appearance at IPO listing ceremony  Hindustan Times
5. Swiggy shares list at ₹420 on NSE, opening 7.7% above IPO price in a highly anticipated debut  Mint