1. Hallo kroket! Mike De Decker vermorzelt Michael Smith en treft Luke Littler in Grand Slam of Darts  Gazet van Antwerpen
2. Sterke Van den Bergh en De Decker stoten door in Grand Slam of Darts, onverwachte exit Van Gerwen  sporza.be
3. VIDEO. Hallo kroket! Mike De Decker vermorzelt Michael Smith en treft Luke Littler in 1/8ste finale Grand Slam of Darts  Het Nieuwsblad
4. VIDEO. Dimitri Van den Bergh flitst naar 1/8ste finales Grand Slam of Darts, met dank aan een muntje: “Ik ga iets uit mijn achterzak pakken...”  Gazet van Antwerpen
5. Mike De Decker bij laatste 16 op Grand Slam of Darts  RTV

Twitter has been my main internet stomping ground since 2009, but I've been withdrawing my labo(u)r from it since October, when it became much more volatile for some reason. 

The New York Times Spelling Bee has been my morning-coffee activity for some of those years, and since November 2020 I've been jokingly tweeting the BrE words that it hasn't accepted. These go in a thread of posts that always start: 

Perfectly Common BrE Words the @NYTimesGames Spelling Bee Has Denied Me: An Occasional Series

Twitter has really degraded this week, which is making me feel a bit sad that perhaps that thread will have to die. (I'm also sad that the thread has frayed along the way—it's very difficult to read it all the way to the beginning because it splits here and there.) So as a clearly procrastinatory measure, I'm putting the list of "perfectly common BrE words" here, with a little more explanation than they tended to get on Twitter.

For those who don't know the Bee: it's an anagram game where one must use the middle letter. The twist—and what makes it a superior anagram game—is that you can use any of the letters as many times as you like. Here's what it looked like on the 5th of April when I hadn't yet got to Genius level.  (My goal every day is 'make it to Genius before breakfast'. It's nice to be called 'Genius' before you've started work.) 

The game, of course, has its own word list, which is suitably American for its New York Times home. Still, some not-usually-AmE words are playable, like FLATMATE, LORRY and PRAM. But many words that are part of my everyday vocabulary in England are not playable. And non-AmE spellings are generally not playable. 

There's been a lot of attention to AmE words that (orig. AmE) stump non-American players in Wordle. (Here's Cambridge Dictionary's 2022 Word of the Year post, which covers some—and includes a video in which I talk about why HOMER was a great choice for Word of the Year.) Not as much attention has been paid to the Spelling Bee, which you need to subscribe to. I'm sure British players have their own (mental) lists of American words they've had to learn in order to get "Queen Bee" status (finding all the day's words) in the game. If you're one of them, do use the comments to tell us about those weird words.

So, after all that preamble, here are the "Perfectly Common BrE Words the @NYTimesGames Spelling Bee Has Denied Me" words in alphabetical order, with translations or links to other blog posts. But first, a bit more preamble. The disclaimers! 

• Words in the puzzle must be at least four letters long, so some of these are suffixed forms for which the three-letter base word was unplayable. If there's an -ED form but not an -ING form (etc.), that'll be because the other one's letters weren't in the puzzle. 
• Some of these would not have been allowable—regardless of their dialectal provenance—on the basis that they are "naughty" words. I include them anyway. 
• I have checked questionable cases against the GloWbE corpus to ensure that the word really is more common in BrE than AmE.
• Some are Irish or Australian by origin, but they are still more common in BrE than in AmE.
• Sometimes my spelling is a bit liberal here. If I could find one British dictionary that allowed me the word with the given spelling, I included it.  
• Also the phrase "perfectly common" is not meant to be taken too seriously!
• These words were not playable at the time when I tried to play them. The word list may have changed and some of them may be playable now. 
• Red ones are ones that have been unsuccessfully played/tweeted about since I first started this blog list. Green ones have been added to the blog since the original post, but were tweeted-about earlier than that—I just missed them in the tangled Twitter threads when I was writing the blog post. 

AGGRO aggression, aggressive behavio[u]r

AITCH  the letter. Less need to spell it as a word in AmE. See this old post.

ANAEMIA / ANAEMIC  AmE anemia/anemic

ANNEXE  minority spelling in BrE; usually, as in AmE, it's annex

APNOEA  AmE apnea

APPAL   AmE appall; old post on double Ls

ARDOUR   old post on -or/-our

ARMOUR    -or/-our

BALLACHE   something annoying or tedious (usually hyphenated, but some dictionaries include the closed-up version)

BIBBED  I don't know why this shows up more in BrE data, but it does, just meaning 'wearing a bib'

BINMAN / BINMEN  AmE garbage man (among other terms); old post on bin

BINT  derogatory term for a woman

BITTY having lots of unconnected parts, often leaving one feeling unsatisfied; for example, this blog post is a bit bitty

BLAG covered in this old post

BLUB / BLUBBING to sob (= general English blubbering)

BOAK retch, vomit, throw up a bit in the mouth. That was gross. Sorry.

BOBBLY having bobbles 

BOBBY  I think this one might be playable now. Informal term for police officer. In AmE, found in bobby pins. 

BODGE / BODGED make or fix something badly

BOFFIN  see this old post

BOLLOCK / BOLLOCKED  reprimand severely

BOLLOX  This one's more common in Irish English than BrE. To screw something up.

BOKE   see BOAK 

BONCE  the head (informal)

BOYO a boy/man (Welsh informal)

BRILL  short for brilliant, meaning 'excellent'; also a kind of European flatfish

BROLLY  umbrella (informal)

BUNG / BUNGING to put (something) (somewhere) quickly/carelessly. People cooking on television are always bunging things in the oven. 

BUTTY  see this old post

CAFF  a café, but typically used of the kind that is analogous to an AmE diner (that is to say a café is not as fancy in BrE as it would be in AmE)

CAWL  a soupy Welsh dish (recipe); also a kind of basket

CEILIDH  a Scottish social dance (event)

CHANNELLED   post on double Ls

CHAPPIE  a chap (man)

CHAV / CHAVVY  see this old post and/or this one

CHICANE  a road arrangement meant to slow drivers down; see this old post

CHILLI  see this old post

CHIMENEA / CHIMINEA the 'e' spelling is considered etymologically "correct" but the 'i' spelling seems to be more common in UK; I think these kinds of outdoor fireplaces are just more trendy in UK than in US?

CHIPPIE alternative spelling of chippy, informal for a (fish and) chip shop

CHOLLA  a spelling of challah (the bread) 

CLAG  mud; more common is claggy for 'having a mud-like consistency'

COLOUR    -or/-our

CONNEXION this is a very outdated spelling of connection. Not actually used in UK these days, but wouldn't it be nice to be able to play it?

COOTCH  a hiding place, a shed or similar (from Welsh cwtch)

COUNCILLOR  post on double Ls

CRAIC it's really an Irish one (a 'good time'), but it qualifies here because it's used more in BrE than AmE (and understood pretty universally in UK)

CRIM  criminal

CUTTY  short (in some UK dialects)

DADO  as in dado rail, what's often called a chair rail in AmE (here's a picture)

DEFENCE  AmE defense

DEMOB /DEMOBBED  de-mobilize(d); that is, released from the (BrE) armed forces / (AmE) military

DENE  a valley (esp. a narrow, wooded one) or a low sand dune near the sea (regional)

DEVILLED  post on double Ls

DIALLING  post on double Ls

DIDDY    small (dialectal); see this old post

DOBBED / DOBBING  actually Australian, dob = to inform on someone; see this old post on the BrE equivalent grass (someone) up

DODDLE  it's a doddle  = (orig. AmE) it's a piece of cake (very easy)

DOOLALLY  out of one's mind

EQUALLED   post on double Ls

FAFF / FAFFING  one of the most useful BrE words. See this old post. 

FARL  a kind of (AmE) quick bread, usually cut into triangles; can be made of various things, but here's a recipe for a common kind, the potato farl

FAVOUR   -or/-our

FILMIC cinematic, relating to film

FITMENT = AmE fixture, i.e. a furnishing that is fit(ted) in place

FLANNELETTE = AmE flannel  old post on flannels

FLAVOUR   -or/-our

FLAVOURFUL   -or/-our

FOETAL AmE (and BrE medical) fetal

FOOTMAN a servant or (formerly soldier (of a particular rank)

FUELLED  post on double Ls

FULFIL   post on double Ls

GADGIE / GADGE guy, man, boy (regional)

GAMMON  this post covers the meat meaning, but lately it's also used as an insult for Brexiteers and their political similars

GAMMY  (of a body part) not working well; e.g., I have a gammy knee

GANNET a type of sea bird, but also BrE slang for a greedy person

GAOL  now less common spelling for jail

GIBBET  gallows; to hang (a person) [not really in current use]

GIGGED / GIGGING  to perform at a gig  [playable as of May 2023]

GILET   covered at this clothing post and also at this pronunciation post

GIPPING form of gip, a synonym of BOAK (see above)

GITE French, but used in English for a type of holiday/vacation cottage

GOBBED / GOBBING  form of gob, which as a noun means 'mouth', but as a verb means 'spit'

GOBBIN waste material from a mine

GOBBY mouthy

GOOLY (more often GOOLIE, GOOLEY) a testicle (informal, see GDoS)

GURN / GURNING  see this old post

HAITCH  = AITCH, but pronounced differently See this old post.

HALLO old-fashioned hello 

HENCH strong, fit (like a weightlifter)

HOLDALL  a duffel bag or similar heavy-duty bag; often spelled with a hyphen (hold-all), but at least some places don't. 

HOOPOE a kind of bird (mostly African), which sometimes makes it to England

HOGMANAY it is a proper noun, but I wanted to include it anyway

HOICK / HOIK  to lift/pull abruptly

HOTCHPOTCH  AmE hodgepodge

INNIT invariant tag question: isn't it? 

INVIGILATING AmE proctoring; old post

JAMMY  lucky; old post 

KIRK  church (Scotland)

KIPPING  form of kip, to take a nap

LAIRY  (esp. of a person) unpleasantly loud, garish 

LAMBING  form of to lamb, give birth to lambs. Often heard in lambing time or lambing season

LAMPED  form of to lamp, to hit a person very hard

LARKING  form of to lark,  'to behave in a silly way for fun'

LAYBY  AmE turnout (and other synonyms/regional terms); a place where a car can move out of the flow of traffic (usually has a hyphen lay-by, but I found one dictionary that doesn't require it)

LIDO an outdoor public swimming pool; there's some debate about how to pronounce it 

LILO  a blow-up mattress for floating on in a pool

LINO  short for linoleum

LOLLY  lollipop or (AmE) popsicle (especially in ice lolly)

LOVAGE  a(n) herb that Americans don't see very often  [has been added! Played successfully on 3 May 2023]

LUPIN  AmE lupine, a flower

LURGI / LURGY  see this old post

MEDIAEVAL  the less common spelling of medieval

MILLIARD  (no longer really used) a thousand million, i.e. a billion 

MILORD address term for a nobleman

MINGE  a woman's pubic hair/area (not flattering) 

MINGING  foul, bad smelling, ugly (rhymes with singing!)

MODELLED  post on double Ls

MOGGY  a cat (informal)

MOOB  man boob

MOULT    AmE molt (related to  -or/-our)

MOZZIE  mosquito

MUPPET in its lower-case BrE sense: 'idiot; incompetent person'

NAFF  this has come up in posts about 'untranslatables' and about a study that identified common BrE words Americans don't know

NAPPY AmE diaper

NAVVY  a manual labo(u)rer (old-fashioned)

NEEP  Scottish English for what the English call a swede and what Americans call a rutabaga (old post on the latter two)

NELLY in the BrE phrase not on your nelly (= AmE not on your life)

NIFFY unpleasant-smelling

NOBBLE  to unfairly influence an outcome; steal 

NOBBLY  alternative spelling of knobbly (which is more common in both AmE & BrE)

NONCY  adjective related to nonce (sex offender, p[a]edophile) 

NOWT  nothing (dialectal)

ODOUR    -or/-our

OFFENCE  AmE offense

OFFIE  short for BrE off-licence; AmE liquor store  (discussed a little in this old post) 

ORACY  the speaking version of literacy; in US education, it's called orality

PACY  having a good or exciting pace (e.g. a pacy whodunnit)

PAEDO  short for pa(e)dophile

PANTO see this post

PAPPED / PAPPING  from pap, to take paparazzi pictures

PARLOUR    -or/-our

PARP  a honking noise

PEDALLED   post on double Ls

PELMET  another one from the study that identified common BrE words Americans don't know

PENG  slang for 'excellent' 

PIEMAN / PIEMEN this one is usually two words (pie man), but I was able to find a dictionary that allowed it as a single word, so I added it to the list

PIPPED / PIPPING  pip = to defeat by a small amount; often heard in to be pipped at the post 

PITTA another spelling for pita, more in line with the BrE pronunciation of the word

PLAICE another one from the study that identified common BrE words Americans don't know

PLUMMY  see this post

PODGY  chubby

POMMY another Australian one, but English people know it because it's an insult directed at them, often in the phrase pommy bastard

PONCE / PONCY  see this post

PONGING horrible-smelling

POOED / POOING  see this post for the poo versus poop story

POOTLE to travel along at a leisurely speed

POPPADOM / POPPADUM anything to do with Indian food is going to be found more in UK than US

PORRIDGY  like porridge, which in AmE is oatmeal

PUFFA full form: puffa jacket; a kind of quilted jacket; it is a trademark, but used broadly; I did find it in one dictionary with a lower-case p

PUNNET  see this old post

RAILCARD  you buy one and it gives you discounts on train tickets

RANCOUR    -or/-our

RUMOUR     -or/-our

TANNOY  AmE loudspeaker, public address system  (originally a trademark, but now used generically)

TARTY dressed (etc.) in a provocative manner

TELLY  (orig.) AmE tv

TENCH a Eurasian fish

THALI  another Indian menu word 

THICKO  stupid person

TIDDY  small (dialectal) 

TIFFIN  usually referring to chocolate tiffin (recipe)

TINNING  AmE canning

TITBIT see this post

TITCH  a small person 

TIZZ = tizzy (to be in a tizz[y])

TOFF  an upper-class person (not a compliment)

TOMBOLA  see this post

TOTTED / TOTTING  see this post 

TOTTY  an objectifying term for (usually) a woman

TRUG  a kind of basket; these days, often a handled rubber container  

TUPPENCE  two pence

UNEQUALLED   post on double Ls

UNVETTED related to my 2008 Word of the Year 

VALOUR   -or/-our

VIVA  an oral exam (short for viva voce)

WANK / WANKING  my original Word of the Year (2006!)

WEEING  AmE peeing

WELLIE  / WELLY  a (BrE) wellington boot / (AmE) rubber boot

WHIN a plant (=furze, gorse)

WHINGE  AmE whine (complain)

WILLIE / WILLY  penis

WOAD a plant used to make blue dye

WOLD a clear, upland area (mostly in place names now)

WOOLLEN   post on double Ls

YOBBO / YOBBY  hooligan / hooliganish

YODELLED   post on double Ls

Halloween is creeping up on us. The rush is on to find the perfect pumpkin, the spookiest costume, and the best candy for trick-or-treaters. However, along with all this excitement comes potential fire hazards related to seasonal decor and costumes. Fortunately, fire risks can be avoided by following the National Fire Protection Association’s (NFPA) Halloween safety precautions.

CATL , the world's top battery maker, will consider building a U.S. plant if President-elect Donald Trump opens the door to Chinese investment in the electric-vehicle supply chain, the company's founder and chairman, Robin Zeng, told Reuters.

In This Article: NINGDE, China (Reuters) - CATL, the world's top battery maker, will consider building a U.S. plant if President-elect Donald Trump opens the door to Chinese investment in the electric-vehicle supply chain, the company's founder and chairman, Robin Zeng, told Reuters. "Originally,…

China battery giant CATL would build US plant if Trump allows it, chairman says Trump wants to block Chinese EV, battery imports but open to US plants with American workers Contemporary Amperex Technology (CATL), the world’s top battery maker, will consider building a US plant if president-elect…

Mika’s beloved tale comes to Xbox for the first time, with updated graphics and a new photo mode. Explore Kaltenbach, bond with Windstorm, and uncover hidden secrets. Embark on a journey like no other as Windstorm: Start of a Great Friendship – Remastered gallops onto Xbox for the first time! Dive into the captivating world […]

The post Windstorm: Start of a Great Friendship – Remastered Gallops onto Xbox appeared first on Xbox Wire.

Carry Smith wrote her PhD thesis on the Voting Rights Act and challenges to the right to vote in Georgia. Now dig this: Smith, the expert on challenges to voting rights, lost her vote because a Republican vigilante challenged her registration—along with 900 other Savannah voters—until she was forced to... READ MORE

A misspelling of former President Donald Trump's name occurred on an optional ballot review screen in Virginia, prompting an unfounded claim on social media of "election fraud." The error was a typo that appeared only on the ballot review screen, not on actual ballots, and would not affect any votes, election officials said.

The post Typo in Trump’s Name on Ballot Review Screen Is Not ‘Election Fraud’ appeared first on FactCheck.org.

From Variety:

Join us for a conversation with two of the nation’s leading election scholars about the county line, preserving free and fair elections in New Jersey, and the future of elections in the United States.

This time of the year there is an urge for holidays and amusement. Halloween is one of those best occasions to take a break from your daily routine and to fully enjoy this very special night of the year. We sincerely wish you a Happy Halloween and a great holiday season. Have fun and stay […]

The post Happy Halloween! appeared first on RSSground.com.

We are welcoming this holiday season! And they are coming for you. Our spooky scary-good updates are lurking out there, but there is no need to fear because we are always working to enhance your online experience. We have just added: IFTTT integration – ability to automate posting to many more destinations and collect more targeted […]

The post Happy Halloween! appeared first on RSSground.com.

A look at the latest gear to cross our desks.
( Photos: 18, Comments: 88 )

Holidaymakers hit in the pocket will visit somewhere else, warned Steve Heapy

Aston Martin technical director Dan Fallows leaves his role with the Formula 1 team.

The American Civil Liberties Union wanted to keep “finding” more ballots for the election in Arizona ad infinitum, but the state’s Supreme Court finally denied their demands. The deadline for accepting more ballots in Arizona is already an absurd Nov. 10, five full days after Election Day. But the AZ ACLU wanted to keep miraculously […]

The post Court Denies Arizona ACLU’s Bid to Keep Counting More Ballots appeared first on The Lid.

The main protease (3CL Mpro) from SARS–CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL Mpro possesses an unusual catalytic dyad composed of Cys145 and His41 residues. A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active-site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus. Here, we present the room-temperature neutron structure of 3CL Mpro, which allowed direct determination of hydrogen atom positions and, hence, protonation states in the protease. We observe that the catalytic site natively adopts a zwitterionic reactive form in which Cys145 is in the negatively charged thiolate state and His41 is doubly protonated and positively charged, instead of the neutral unreactive state usually envisaged. The neutron structure also identified the protonation states, and thus electrical charges, of all other amino acid residues and revealed intricate hydrogen-bonding networks in the active-site cavity and at the dimer interface. The fine atomic details present in this structure were made possible by the unique scattering properties of the neutron, which is an ideal probe for locating hydrogen positions and experimentally determining protonation states at near-physiological temperature. Our observations provide critical information for structure-assisted and computational drug design, allowing precise tailoring of inhibitors to the enzyme's electrostatic environment.

G protein–coupled receptors (GPCRs) initiate signaling cascades via G-proteins and beta-arrestins (βarr). βarr-dependent actions begin with recruitment of βarr to the phosphorylated receptor tail and are followed by engagement with the receptor core. βarrs are known to act as adaptor proteins binding receptors and various effectors, but it is unclear whether in addition to the scaffolding role βarrs can allosterically activate their downstream targets. Here we demonstrate the direct allosteric activation of proto-oncogene kinase Src by GPCR–βarr complexes in vitro and establish the conformational basis of the activation. Whereas free βarr1 had no effect on Src activity, βarr1 in complex with M2 muscarinic or β2-adrenergic receptors reconstituted in lipid nanodiscs activate Src by reducing the lag phase in Src autophosphorylation. Interestingly, receptor–βarr1 complexes formed with a βarr1 mutant, in which the finger-loop, required to interact with the receptor core, has been deleted, fully retain the ability to activate Src. Similarly, βarr1 in complex with only a phosphorylated C-terminal tail of the vasopressin 2 receptor activates Src as efficiently as GPCR–βarr complexes. In contrast, βarr1 and chimeric M2 receptor with nonphosphorylated C-terminal tail failed to activate Src. Taken together, these data demonstrate that the phosphorylated GPCR tail interaction with βarr1 is necessary and sufficient to empower it to allosterically activate Src. Our findings may have implications for understanding more broadly the mechanisms of allosteric activation of downstream targets by βarrs.

Mammalian circadian clocks are driven by transcription/translation feedback loops composed of positive transcriptional activators (BMAL1 and CLOCK) and negative repressors (CRYPTOCHROMEs (CRYs) and PERIODs (PERs)). CRYs, in complex with PERs, bind to the BMAL1/CLOCK complex and repress E-box–driven transcription of clock-associated genes. There are two individual CRYs, with CRY1 exhibiting higher affinity to the BMAL1/CLOCK complex than CRY2. It is known that this differential binding is regulated by a dynamic serine-rich loop adjacent to the secondary pocket of both CRYs, but the underlying features controlling loop dynamics are not known. Here we report that allosteric regulation of the serine-rich loop is mediated by Arg-293 of CRY1, identified as a rare CRY1 SNP in the Ensembl and 1000 Genomes databases. The p.Arg293His CRY1 variant caused a shortened circadian period in a Cry1−/−Cry2−/− double knockout mouse embryonic fibroblast cell line. Moreover, the variant displayed reduced repressor activity on BMAL1/CLOCK driven transcription, which is explained by reduced affinity to BMAL1/CLOCK in the absence of PER2 compared with CRY1. Molecular dynamics simulations revealed that the p.Arg293His CRY1 variant altered a communication pathway between Arg-293 and the serine loop by reducing its dynamicity. Collectively, this study provides direct evidence that allosterism in CRY1 is critical for the regulation of circadian rhythm.

Phospholipase Cε (PLCε) is activated downstream of G protein–coupled receptors and receptor tyrosine kinases through direct interactions with small GTPases, including Rap1A and Ras. Although Ras has been reported to allosterically activate the lipase, it is not known whether Rap1A has the same ability or what its molecular mechanism might be. Rap1A activates PLCε in response to the stimulation of β-adrenergic receptors, translocating the complex to the perinuclear membrane. Because the C-terminal Ras association (RA2) domain of PLCε was proposed to the primary binding site for Rap1A, we first confirmed using purified proteins that the RA2 domain is indeed essential for activation by Rap1A. However, we also showed that the PLCε pleckstrin homology (PH) domain and first two EF hands (EF1/2) are required for Rap1A activation and identified hydrophobic residues on the surface of the RA2 domain that are also necessary. Small-angle X-ray scattering showed that Rap1A binding induces and stabilizes discrete conformational states in PLCε variants that can be activated by the GTPase. These data, together with the recent structure of a catalytically active fragment of PLCε, provide the first evidence that Rap1A, and by extension Ras, allosterically activate the lipase by promoting and stabilizing interactions between the RA2 domain and the PLCε core.