STLFLX AirGUARDZ, powered by AIR+ Smart Mask, is a revolutionary innovation in protective mask technology.

Greenheck has added three new models to its line of high-performance residential energy recovery ventilators (ERVs).

Ventilator-associated pneumonia (VAP) is a common hospital-acquired infection, leading to high morbidity and mortality. Currently, bronchoalveolar lavage (BAL) is used in hospitals for VAP diagnosis and guiding treatment options. Although BAL collection procedures are invasive, alternatives such as endotracheal aspirates (ETA) may be of diagnostic value, however, their use has not been thoroughly explored. Longitudinal ETA and BAL were collected from 16 intubated patients up to 15 days, of which 11 developed VAP. We conducted a comprehensive LC–MS/MS based proteome and metabolome characterization of longitudinal ETA and BAL to detect host and pathogen responses to VAP infection. We discovered a diverse ETA proteome of the upper airways reflective of a rich and dynamic host-microbe interface. Prior to VAP diagnosis by microbial cultures from BAL, patient ETA presented characteristic signatures of reactive oxygen species and neutrophil degranulation, indicative of neutrophil mediated pathogen processing as a key host response to the VAP infection. Along with an increase in amino acids, this is suggestive of extracellular membrane degradation resulting from proteolytic activity of neutrophil proteases. The metaproteome approach successfully allowed simultaneous detection of pathogen peptides in patients' ETA, which may have potential use in diagnosis. Our findings suggest that ETA may facilitate early mechanistic insights into host-pathogen interactions associated with VAP infection and therefore provide its diagnosis and treatment.

Devices being used to treat chronic conditions, COVID-19 Delaware Insurance Commissioner Trinidad Navarro has released a consumer alert for users of respiratory devices manufactured by Philips. An estimated 4 million Philips Continuous Positive Airway Pressure (CPAP) and Bi-Level Positive Airway Pressure (BiPAP or BiLevel PAP) devices, as well as mechanical ventilators manufactured before April 26, […]

Former President Pranab Mukherjee's health took a dip on Tuesday evening, following emergency brain surgery, and he remains on ventilator support. "The

This ventilator may not look like an important piece of medical equipment but it may be one of the critical things keeping Covid-19 patients alive. MIT has designed an emergency ventilator that uses commonly found and easily sourced materials. FDA-approved ventilators are expensive and require hundreds of components, and in these trying times a cheaper alternative may be able to save lives as these machines become more scarce.

It was developed with CSIR-National Aerospace Laboratories

The start-up mentors debated if they could drive the price further down, but feared an even lower price would raise doubts about its quality, as was the case with the Tata Nano, reports Amrita Singh.

The following article, NYC Nurse Steals Credit Card From 70-Yr-Old Dying COVID-19 Patient On Ventilator, was first published on 100PercentFedUp.com.

"She is a despicable human being"

Continue reading: NYC Nurse Steals Credit Card From 70-Yr-Old Dying COVID-19 Patient On Ventilator ...

Ashok Leyland, flagship company of the Hinduja group, on Monday announced a slew of initiatives to manufacture and distribute ventilators.

A good ventilator must be a high-precision product, a combination of top-class engineering efforts, optimum manufacturing capability, and robust financial backing.

MUZAFFARABAD: The first patient of Covid-19 had been put on ventilator in the Azad Jammu and Kashmir on Saturday, as nine more cases emerged, taking the tally to 87, while 60 patients have recovered so far.The 85-year-old patient was shifted on ventilator after his condition worsened, said a...

Facebook is rolling out a tool that lets users in the US and Canada transfer photos and videos from its platform to Google Photos, Amazon says it plans to spend all of its profit for the second quarter, an estimated $4 billion, on its response to the coronavirus pandemic, and NVIDIA’s chief scientist rolls out…

51-year-old 'dedicated and loving' nurse Onyenachi Obasi died after fighting for her life for five weeks on a ventilator in intensive care. Her niece has set up a fundraising page to pay for her funeral.

The price of imported ventilators starts from Rs 8 lakh and goes up to as high as Rs 25 lakh a unit.

The device, called VITAL (Ventilator Intervention Technology Accessible Locally), passed a critical test this week at the Icahn School of Medicine in New York, an epicentre of COVID-19 in the US, NASA said.

Today, more than patient advocacy, medical and public health organizations sent a letter to senior Trump Administration officials, appealing to the Administration to take immediate action to alleviate the critical shortage across the nation ventilators...

The present invention relates to a ventilator autoclave comprising a chamber (1) with a space (5) for receiving goods (18) to be sterilized, at least one fan arrangement (2) for circulating steam and/or air in said chamber, and at least one first heat exchanger arrangement (11) for cooling and/or heating said steam and/or air, wherein said fan arrangement is arranged and configured to circulate said steam and/or air in said chamber (1), wherein said chamber (1) is configured such that said steam and/or air that is circulated in said chamber (1) follows a flow path passing at least a part of said first heat exchanger arrangement (11) before reaching said goods (18) to be sterilized, wherein said autoclave further comprises at least one second heat exchanger arrangement (19) that is provided upstream of said first heat exchanger arrangement (11) in said flow path, and wherein said second heat exchanger arrangement (19) is provided at such a distance from the periphery of said fan arrangement (2) that said flow of steam and/or air being circulated by said fan arrangement has a tangential velocity component, as seen in relation to the fan arrangement, when it passes said second heat exchanger arrangement (19).

A method for controlling an electric ventilator includes: setting a first threshold temperature T1D of a microcontroller lower than a maximum threshold temperature T3D of the microcontroller; monitoring a temperature TD of the microcontroller; setting a first threshold temperature T1M of an electronic power device lower than a maximum threshold temperature T3M of the electronic power device; monitoring a temperature TM of the electronic power device; preparing a counter of a predetermined time X; activating the counter if the temperature TD or the temperature TM exceeds respective first threshold temperatures T1D, T1M; reducing a speed V of rotation of an electric motor to a second value V1 lower than a first value V1 if after the predetermined time X, the temperature TD or the temperature TM is higher than the respective first threshold temperatures T1D, T1M.

A ventilator (10) comprises a ventilator stator (12) for mounting to a structure and a ventilator rotor (14) for mounting and rotation with respect to the stator. One or more wind drivable elements (44) are mounted to the ventilator rotor. A motor (20) is provided for operation between the ventilator rotor and ventilator stator for selective motor-driven rotation of the ventilator rotor.

“The export of all ventilators including any artificial respiratory apparatus or oxygen therapy apparatus or any other breathing appliance/devices... is prohibited with immediate effect,” the the Directorate General of Foreign Trade (DGFT) said in a notification.

After two weeks of hospitalization, Larry Potter became the first Iowan diagnosed with COVID-19 to be released from Mercy Medical Center in Cedar Rapids after spending time on a ventilator.

“Respirators, ventilators, all of the equipment — try getting it yourselves,” the president told governors in a conference call. The suggestion surprised some governors, who are increasingly looking to the federal government for help.

The pandemic has put a lot of focus on having enough ventilators to help critically ill patients who struggle to breathe. But they carry risks, and concerns have been raised that — in some COVID-19 cases — ventilators may do more harm than good.

Jayson O’Brien survived COVID 19 after 18 days in Dubbo Hospital and 8 days in ICU on ventilator.

Some veterinarians in Tasmania are sceptical about suggestions animal ventilators could be used on humans during the coronavirus pandemic, with some warning making them fit for purpose may be too expensive.

Hypoxia-inducible factor (HIF) is strikingly upregulated in many types of cancer, and there is great interest in applying inhibitors of HIF as anticancer therapeutics. The most advanced of these are small molecules that target the HIF-2 isoform through binding the PAS-B domain of HIF-2α. These molecules are undergoing clinical trials with promising results in renal and other cancers where HIF-2 is considered to be driving growth. Nevertheless, a central question remains as to whether such inhibitors affect physiological responses to hypoxia at relevant doses. Here, we show that pharmacological HIF-2α inhibition with PT2385, at doses similar to those reported to inhibit tumor growth, rapidly impaired ventilatory responses to hypoxia, abrogating both ventilatory acclimatization and carotid body cell proliferative responses to sustained hypoxia. Mice carrying a HIF-2α PAS-B S305M mutation that disrupts PT2385 binding, but not dimerization with HIF-1β, did not respond to PT2385, indicating that these effects are on-target. Furthermore, the finding of a hypomorphic ventilatory phenotype in untreated HIF-2α S305M mutant mice suggests a function for the HIF-2α PAS-B domain beyond heterodimerization with HIF-1β. Although PT2385 was well tolerated, the findings indicate the need for caution in patients who are dependent on hypoxic ventilatory drive.

Led by Princeton’s Cristian Galbiati, a massive international team worked to design, test and finalize the Mechanical Ventilator Milano (MVM), a low-cost ventilator designed to ease device shortages caused by COVID-19.

Drägerwerk is a world leader in the production of ventilators. In an interview, company head Stefan Dräger, 57, discusses the challenges of keeping up with current demand as the corona crisis accelerates.

Several groups of researchers are testing different methods to divert critically ill COVID-19 patients from needing ventilators in the first place.

With mechanical ventilators in short supply, doctors are scrambling to find alternatives for patients fighting the coronavirus. Here are some of their options.

It's simply wrong when a much younger person dies. Let younger patients take the ventilator if there's a scarcity -- and let doctors make the decision.

COMPUTER services company PTC is using augmented reality , the enhanced visual technology seen in Pokemon Go smartphone games and Iron Man movies, to produce ventilators in record time for the NHS.

Vice President Mike Pence will visit Indiana next week to spotlight an automotive plant making ventilators to fight the COVID 19 pandemic.

Mike Pence will visit Kokomo Thursday to highlight the administration's response to the novel coronavirus pandemic.

General Motors has partnered with Ventec Life Systems to rapidly boost the production of ventilators. It is considering GM's plant in Kokomo, Indiana.

WASHINGTON (AP) — President Donald Trump, who’s taken to calling the US the “king” of ventilators, is making plans to ship 8,000 of the breathing machines to foreign countries by the end of July to help in their fight...

The province's networks of labs processed 15,179 tests in the last 24 hours, more than any of the three days previous but still short of the 16,000 tests per day target set back in April.

Respiratory outcomes of patients with bronchopulmonary dysplasia (BPD) range from no oxygen requirement to chronic respiratory failure. Outcomes of least severe types of BPD are well described. Limited data exist on outcomes of patients with BPD-related chronic ventilator dependency.

Along with a first estimation of the incidence of patients with severe BPD-related chronic respiratory failure who were dependent on positive pressure ventilation via tracheostomy at home, we describe their survival rate, liberation from positive pressure ventilation, and decannulation. (Read the full article)

Objectives: Carbapenemase-producing Enterobacterales and specifically KPC-producing Klebsiella pneumoniae (KPC-Kp) are rapidly spreading worldwide. The prognosis of ventilator-associated pneumonia (VAP) caused by KPC-producing Klebsiella pneumoniae (KPC-Kp) is not well known. Our study tries to assess whether ventilator-associated pneumonia caused by a KPC-Kp strain is associated with higher all-cause mortality than if caused by carbapenem-susceptible isolates.

Study design and methods: This is a retrospective cohort study of patients with VAP due to K. pneumoniae from a 35-bed polyvalent Intensive Care Unit in a university hospital (> 40,000 annual admissions) between January 2012 and December 2016. Adjusted multivariate analysis was used to study the association of KPC-Kp with 30-day all-cause mortality (Cox regression).

Results. We analyze 69 cases of K. pneumoniae VAP of which 39 were produced by a KPC-Kp strain with high-level resistance to meropenem (MIC > 16 mg/mL). All-cause mortality at 30 days was 41% in the KPC-Kp group (16/39) and 33.3% in the carbapenem-susceptible cases (10/30). KPC-Kp etiology was not associated with higher mortality when controlled for confounders (adjusted hazard ratio [lsqb]HR[rsqb] 1.25; 95% CI: 0.46–3.41). Adequate targeted therapy (HR 0.03; 95% CI: <0.01–0.23) was associated with all-cause mortality.

Conclussion. Assuming the limitations due to the available sample size, the prognosis of VAP caused by KPC-Kp is similar to VAPs caused by carbapenem-susceptible K. pneumoniae when appropriate treatment is used.

T. Michael O'Shea
Jul 1, 1999; 104:15-21
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This would provide enough isolation to the patient and protection to health workers and family. The ventilator can be controlled using the app and provides real-time display of the waveforms.

COVID-19: The team, which consists of only volunteers, has been working without any funding and is working anonymously so that people do not call them with inquiries about the project.

When Ballarat-based Gekko Systems heard the local medical community was worried about access to ventilators needed to respond to the COVID-19 crisis, the company sprang into action.

NVIDIA Chief Scientist Bill Dally this week released an open-source design for a low-cost, easy-to-assemble mechanical ventilator. The ventilator, designed in just a few weeks by Dally — whose storied technology career includes key contributions to semiconductors and supercomputers — can be built quickly from just $400 of off-the-shelf parts, Dally says. Traditional ventilators, by Read article >

The post NVIDIA Chief Scientist Releases Low-Cost, Open-Source Ventilator Design appeared first on The Official NVIDIA Blog.

NVIDIA Chief Scientist Bill Dally this week released an open-source design for a low-cost, easy-to-assemble mechanical ventilator. The ventilator, designed in just a few weeks by Dally — whose storied technology career includes key contributions to semiconductors and supercomputers — can be built quickly from just $400 of off-the-shelf parts, Dally says. Traditional ventilators, by Read article >

The post NVIDIA Chief Scientist Releases Low-Cost, Open-Source Ventilator Design appeared first on The Official NVIDIA Blog.

ISLAMABAD: Federal Minister for Planning, Development, Reforms, and Special Initiatives Asad Umer Friday said Pakistan would be manufacturing its own ventilators in next two months.Talking in a...

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