Recent research lead by a Melbourne research institute has found that people who carry a particular type of gene have natural resistance against typhoid fever. The Nossal Institute of Global Health at the University of Melbourne conducted the study in collaboration with the Genome Institute of Singapore and Oxford University Clinical Research Unites in Vietnam and Nepal. The research, which is the first large-scale one of its kind, investigated the human natural gene responses to typhoid and associated infectious diseases.

NPR's Mary Louise Kelly talks with Sharon Horgan, creator and star of Bad Sisters, about the show's second season.

 Matternet, a global specialist in urban drone delivery, today announced a strategic partnership with ANRA Technologies, a company who specialises in Unmanned Aircraft Systems (UAS) Traffic Management (UTM) solutions.

Pioneering research has pinpointed key vacuolar transporters in citrus fruits that regulate taste by balancing citric acid and sugar levels. This discovery illuminates the genetic pathways controlling flavor, laying the groundwork for cultivating citrus varieties with optimized sweetness and acidity--a promising development for both consumers and the agricultural sector.

Asset Management Group, Inc. of Stamford, CT, is pleased to announce that Jennifer Brucato has passed the FINRA Series 65 Securities License Exam and has been promoted to Associate Financial Planner.

Concentration Camp Lichtenrade in Berlin was a sub-camp of Concentration Camp Sachsenhausen.

Inrate, a leading impact rating and ESG data company, is thrilled to announce the release of CLIF, its new ESG data platform, designed to provide transparent and traceable ESG data to simply investment analysis. With expanded features and seamless functionality, CLIF allows investors to gain enhanced visibility into the sustainability performance of over 10,000 companies and 190 sovereigns worldwide.   Empowering [PR.com]

Carta: Heb 11: 9-10, 32-40, Evangelio Mt 1: 1-25 El Padre Nicholas predicó unirse a Cristo y hacer su voluntad. Letter: Heb 11: 9-10, 32-40, Gospel: Mt 1: 1-25 Father Nicholas preached to join Christ and do his will.

In our continuing effort to keep you informed about the recent and on going work of our Hierarchs to bring about administrative unity, we present an extensive interview with Fr. Mark Arey. The discussion centers on the first Episcopal Assembly meeting in New York on May 26-28, 2010. You will hear first hand what took place behind the closed doors of the Assembly and how it impacts all of us for the future. Fr. Mark is the current General Secretary of SCOBA (the Standing Conference of Orthodox Bishops in America) and was the initial Secretary of the Assembly in New York. He was one of very few non-Bishops in the meetings.

Whilst I would definitely not claim to be an expert, writing this blog has allowed me to learn a reasonable amount about XML over the years.  Most of the articles I’ve written have been about explaining how to manage the many amazing features in the filetypes that are supported by Trados Studio… and of course … Continue reading XML… unravelling chaos

The study aims to unveil the various determinants that drive the adoption of e-governance services (EGS). Using the UTAUT 3 model, the research investigated these factors within the Indian context. A purposive sampling technique was utilised to collect the samples from 680 respondents through the online survey method. Furthermore, the study employs structural equation modelling (SEM) to examine the structural relationships between the UTAUT3 model's dimensions in the context of e-governance. Findings revealed that the UTAUT3 model adequately predicts the intention to adopt EGS. The present study addressed a significant gap in the literature on EGS and technology adoption by establishing a relationship between different dimensions of the UTAUT3 model and actual usage of EGS. The findings have implications for practitioners and policymakers as they throw light on the effective implementation of e-governance programs, which are essential for providing the citizens with high-quality services.

Aim/Purpose: This study aims to evaluate the success of ERP post-implementation and the factors that affect the overall success of the ERP system by integrating the Task Technology Fit (TTF) model into the Information System Success Model (ISSM). Background: Not all ERP implementations provide the expected benefits, as post-implementation challenges can include inflexible ERP systems and ongoing costs. Therefore, it is necessary to evaluate the success after ERP implementation, and this research integrates the Task Technology Fit (TTF) model into the Information System Success Model (ISSM). Methodology: For data analysis and the proposed model, the authors used SmartPLS 3 by applying the PLS-SEM test and one-tailed bootstrapping. The researchers distributed questionnaires online to 115 ERP users at a construction company in Indonesia and successfully got responses from 95 ERP users. Contribution: The results obtained will be helpful and essential for future researchers and Information System practitioners – considering the high failure rate in the use of ERP in a company, as well as the inability of organizations and companies to exploit the benefits and potential that ERP can provide fully. Findings: The results show that Perceived Usefulness, User Satisfaction, and Task-Technology Fit positively affect the Organizational Impact of ERP implementation. Recommendations for Practitioners: The findings can help policymakers and CEOs of businesses in Indonesia’s construction sector create better business strategies and use limited resources more effectively and efficiently to provide a considerably higher probability of ERP deployment. The findings of this study were also beneficial for ERP vendors and consultants. The construction of the industry has specific characteristics that ERP vendors should consider. Construction is a highly fragmented sector, with specialized segments demanding specialist technologies. Several projects also influence it. They can use them to identify and establish several alternative strategies to deal with challenges and obstacles that can arise during the installation of ERP in a firm. Vendors and consultants can supply solutions, architecture, or customization support by the standard operating criteria, implement the ERP system and train critical users. The ERP system vendors and consultants can also collaborate with experts from the construction sector to develop customized alternatives for construction companies. That would be the most outstanding solution for implementing ERP in this industry. Recommendation for Researchers: Future researchers can use this combined model to study ERP post-implementation success on organizational impact with ERP systems in other company information systems fields, especially the construction sector. Future integration of different models can be used to improve the proposed model. Integration with models that assess the level of Information System acceptance, such as Technology Acceptance Model 3 (TAM3) or Unified Theory of Acceptance and Use of Technology 2 (UTAUT2), can be used in future research to deepen the exploration of factors that influence ERP post-implementation success in an organization. Impact on Society: This study can guide companies, particularly in the construction sector, to maintain ERP performance, conduct training for new users, and regularly survey user satisfaction to ensure the ERP system’s reliability, security, and performance are maintained and measurable. Future Research: It is increasing the sample size with a larger population at other loci (private and state-owned) that use ERP to see the factors influencing ERP post-implementation success and using mixed methods to produce a better understanding. With varied modes, it is possible to get better results by adding unique factors to the research, and future integration of other models can be used to improve the proposed model.

Aim/Purpose: This study aims to investigate the influence of e-government public services on public trust at the local government level, addressing the pressing need to understand the factors shaping citizen perceptions and trust in government institutions. Background: With the proliferation of e-government initiatives worldwide, governments are increasingly turning to digital solutions to enhance public service delivery and promote transparency. However, despite the potential benefits, there remains a gap in understanding how these initiatives impact public trust in government institutions, particularly at the local level. This study seeks to address this gap by examining the relationship between e-government service quality, individual perceptions, and public trust, providing valuable insights into the complexities of citizen-government interactions in the digital age. Methodology: Employing a quantitative approach, this study utilises surveys distributed to users of e-government services in one of the regencies in Indonesia. The sample consists of 278 individuals. Data analysis is conducted using Partial Least Squares Structural Equation Modelling, allowing for the exploration of relationships among variables and their influence on public trust. Contribution: This study provides insights into the factors influencing public trust in e-government services at the local government level, offering a nuanced understanding of the relationship between service quality, individual perceptions, and public trust. Findings: This study emphasises information quality and service quality in e-government-based public services as crucial determinants of individual perception in rural areas. Interestingly, system quality in e-government services has no influence on individual perception. In the individual perception, perceived security and privacy emerge as the strongest antecedent of public trust, highlighting the need to guarantee secure and private services for citizens in rural areas. These findings emphasise the importance of prioritising high-quality information, excellent service delivery, and robust security measures to foster and sustain public trust in e-government services. Recommendations for Practitioners: Practitioners must prioritise enhancing the quality of e-government services due to their significant impact on individual perception, leading to higher public trust. Government agencies must ensure reliability, responsiveness, and the effective fulfilment of user needs. Additionally, upholding high standards of information quality in e-government services by delivering accurate, relevant, and timely information remains crucial. Strengthening security measures through robust protocols such as data encryption and secure authentication becomes essential for protecting user data. With that in mind, the authors believe that public trust in government would escalate. Recommendation for Researchers: Researchers could investigate the relation between system quality in e-government services and individual perception in different rural settings. Longitudinal studies could also elucidate how evolving service quality, information quality, and security measures impact user satisfaction and trust over time. Comparative studies across regions or countries can reveal cultural and contextual differences in individual perceptions, identifying both universal principles and region-specific strategies for e-government platforms. Analysing user behaviour and preferences across various demographic groups can inform targeted interventions. Furthermore, examining the potential of emerging technologies such as blockchain or artificial intelligence in enhancing e-government service delivery, security, and user engagement remains an interesting topic. Impact on Society: This study’s findings have significant implications for fostering public trust in government institutions, ultimately strengthening democracy and citizen-government relations. By understanding how e-government initiatives influence public trust, policymakers can make informed decisions to improve service delivery, enhance citizen engagement, and promote transparency, thus contributing to more resilient and accountable governance structures. Future Research: Future research could opt for longitudinal studies to evaluate the long-term effects of enhancements in service quality, information quality, and security. Cross-cultural investigations can uncover universal principles and contextual differences in user experiences, supporting global e-government strategies in rural areas. Future research could also improve the research model by adding more variables, such as risk aversion or fear of job loss, to gauge individual perceptions.

Aim/Purpose: This research investigated the determinant factors influencing the adoption intentions of Chatsicum, a Knowledge-Based Chatbot (KBC) aimed at enhancing the species literacy of biodiversity students. Background: This research was conducted to bridge the gap between technology, education, and biodiversity conservation. Innovative solutions are needed to empower individuals with knowledge, particularly species knowledge, in preserving the natural world. Methodology: The study employed a quantitative approach using the Partial Least Square Structural Equation Modeling (PLS-SEM) and sampled 145 university students as respondents. The research model combined the Task-Technology Fit (TTF) framework with elements from the Diffusion of Innovation (DOI), including relative advantage, compatibility, complexity, and observability. Also, the model introduced perceived trust as an independent variable. The primary dependent variable under examination was the intention to use the KBC. Contribution: The findings of this research contribute to a deeper understanding of the critical factors affecting the adoption of the KBC in biodiversity education and outreach, as studies in this context are limited. This study provides valuable insights for developers, educators, and policymakers interested in promoting species literacy and leveraging innovative technologies by analyzing the interplay of TTF and DOI constructs alongside perceived trust. Ultimately, this research aims to foster more effective and accessible biodiversity education strategies. Findings: TTF influenced all DOI variables, such as relative advantage, compatibility, observability, and trust positively and complexity negatively. In conclusion, TTF strongly affected usage intention indirectly. However, relative advantage, complexity, and observability insignificantly influenced the intention to use. Meanwhile, compatibility and trust strongly affected the use intention. Recommendations for Practitioners: Developers should prioritize building and maintaining chatbots that are aligned with the tasks, needs, and goals of the target users, as well as establishing trust through the assurance of information accuracy. Educators could develop tailored educational interventions that resonate with the values and preferences of diverse learners and are aligned closely with students’ learning needs, preferences, and curriculum while ensuring seamless integration with the existing educational context. Conservation organizations and policymakers could also utilize the findings of this study to enhance their outreach strategies, as the KBC is intended for students and biodiversity laypeople. Recommendation for Researchers: Researchers should explore the nuances of relationships between TTF and DOI, as well as trust, and consider the potential influence of mediating and moderating variables to advance the field of technology adoption in educational contexts. Researchers could also explore why relative advantage, complexity, and observability did not significantly impact the usage intention and whether specific user segments or contextual factors influence these relationships. Impact on Society: This research has significant societal impacts by improving species literacy, advancing technology in education, and promoting conservation efforts. Species knowledge could raise awareness regarding biodiversity and the importance of conservation, thereby leading to more informed and responsible citizens. Future Research: Future works should address the challenges and opportunities presented by KBCs in the context of species literacy enhancement, for example, interventions or experiments to influence the non-significant factors. Furthermore, longitudinal studies should investigate whether user behavior evolves. Ultimately, examining the correlation between species literacy, specifically when augmented by chatbots, and tangible conservation practices is an imperative domain in the future. It may entail evaluating the extent to which enhanced knowledge leads to concrete measures promoting biodiversity preservation.

If you have read any of the NRA’s magazines, watch American Rifleman, or have seen some shows on The Outdoor Channel or The History Channel, you have seen Mark Keefe for years.

The Baseball Writers' Association of America on Nov. 11 announced the finalists for its Rookie of the Year Awards. Many Boston Red Sox fans take issue with its American League selections. Red Sox rookie Wilyer Abreu was not selected among the three AL ROY finalists. Colton Cowser, Austin Wells and Luis Gil — all AL East rivals — are the three youngsters nominated for this season's title.

[size=13px]Dunraven Arms Hotel Adare, Ireland €20. Only available on 19-20 November 2024. [/size] Image:

Children's Geographies; 10/01/2023
(AN 173035624); ISSN: 14733285
Academic Search Premier

Organizational Research Methods, Ahead of Print. When modeling responses to items measuring non-cognitive constructs that require introspection (e.g., personality, attitude), most studies have assumed that respondents follow the same item response process—either a dominance or an unfolding one. Nevertheless, the results are not equivocal, as some preliminary evidence suggests that some people use an unfolding […]

The post One Size Does Not Fit All: Unraveling Item Response Process Heterogeneity Using the Mixture Dominance-Unfolding Model (MixDUM) was curated by information for practice.

It is not the melting of permafrost that causes giant gas bubbles to erupt, geophysicists found. This crater in Yamal is the 17th such crater that was found in the region.Vasily Bogoyavlensky, geologist and geophysicist, said that there are many of such "black holes" in the north of Russia. Many of those craters have emerged during the past ten years.The very first crater, which was discovered in 2014, became the famous one. It was a hole about 50 meters deep and 40 meters in diameter. Geologists quickly established that the giant hole in the ground was just a hole, from which methane was bursting out.A cavity is formed in the layers of underground ice as it melts due to the influence of a local anomalous heat flow. This cavity is then filled with gas, and it grows larger, causing the surface on the ground to swell until the frozen rock reaches its ultimate strength and eventually explodes in a pneumatic explosion. Extraterrestrial cryovolcanoes found on Earth Some scientists assumed that the Yamal crater was the first cryovolcano on planet Earth - a volcano that appears in permafrost and spews out jets of gas instead of melted magma. Until recently, such cryovolcanoes were observed only in space - on Neptune's satellite Triton, and on Titan or Enceladus (the moons of Saturn). According to Vasily Bogoyavlensky, the Yamal gas eruptions can be referred to as volcanoes only to a certain degree, although several craters can be defined as such. "I believe that many of these objects can be categorised as ordinary mud volcanoes, but they have their own peculiarities, because the near-surface soil is frozen. It additionally restrains the gas, and the pressure in the cavity can reach high values. As a result, the gas still breaks through the rock," the researcher said.

Tenral specialises in high-quality, sheet metal fabrication solutions and uses advanced technology to enhance their service.

A Heartfelt Story of Hope, Humanity, and Compassion

RobobAI helps businesses shift their spend to more ethical and sustainable suppliers

Arizona Sunrays, a premier gymnastics training center, is thrilled to announce its lineup of dynamic and engaging summer camps for 2024.

Arizona Sunrays Gymnastics and Dance Center recently hosted a spectacular "Olympic Watch Party" at their Phoenix gym, uniting families, young athletes, and the local community to celebrate the Olympic spirit.

Jeffrey Erez, the Miami-based law firm's managing partner, reports that more than a dozen similar customer complaints are pending against Stifel, Nicolaus & Co., Inc., to recover losses allegedly caused by the actions of broker Chuck A. Roberts.

Imagine Motorhead Meets the Ramones & You have the original "They Call Me Energy" while the whimsical original "A Night at The Space Opera" sounds a bit like Pink Floyd with Syd Barrett meets the early Who. Now available at Amazon & other fine sites

What were galaxies like in the early universe? This is what a recent study published in The Astronomical Journal hopes to address as an international team

In the pursuit of optimal health, "superfoods" have emerged as potent allies, captivating health enthusiasts and filling shopping carts worldwide

Soon after the mass shooting at Columbine High School in 1999, leaders of the National Rifle Association held a conference call to craft their response. Secret tapes from this call obtained by NPR's Investigations team reveal how the NRA developed what would become their standard response after decades of school shootings. | Listen to the original Up First episode: n.pr/nratapes

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New Video: The Damn Fool Idealistic Crusader channel on Youtube has posted a wonderful overview of the James Bond story, Moonraker, covering everything from Fleming's original story and the comic and film adaptations to the many published editions and graphic designs we've seen over the years. It's super in-depth and fun! Watch here on Youtube. Moonraker is one of the Fleming novels I go back to most and I even own a few original comic strips by John McLusky from the famous car chase scene in the story. And despite its silly humor, I even find myself rewatching the Roger Moore film every few years (I think I was the perfect age for it when it came out!). Another version I've enjoyed a lot is the audiobook edition by actor Bill Nighy, which was released in a great box set of Fleming audiobooks read by prominent actors. The set was out of print for a long time, but it looks like you can get individual CDs or audio files on Amazon (Moonraker here). Below: Richie Fahey's pulp-styled cover design from 2002. 

Guide for NRAs on International Mobile Roaming Cost analysis - Technical Paper

SnapNrack and CertainTeed join forces to offer seamless warranties for solar installations on residential roofs, ensuring peace of mind for homeowners and installers.

Las penurias de un bar asediado junto a la Cañada Real, con portero automático para abrir sólo a los conocidos

Sobre Besteiro

Lo peor no es que el ayudante del mago más famosos del mundo sea un farsante, sino el silencio cómplice y decepcionante de los que no le piden una explicación.

“the Lunar Mirage: Unraveling The Moon Landing Hoax”

On the Disney Night, the Top 10 of the current season 19 hit the stage to sing Disney classics with host Ryan Seacrest announcing Arthur Gunn, the runner-up of season 18, as the Comeback winner.

In 2003, Brunswick prosecutors convicted Dennis Perry of killing a couple in their church back in 1985 — while another suspect had admitted to the murder on tape. Renewed interest in the case from the Georgia Innocence Project and a true crime podcast spurred Joshua Sharpe, criminal justice reporter for the Atlanta Journal-Constitution , to revisit an early suspect’s alibi. Sharpe's research unveiled new DNA evidence, and prompted the Georgia Bureau of Investigation to reopen the case. Sharpe joins On Second Thought to talk us through what he learned in his nearly year of reporting on the 35 year-old case.

Special guest Rosemary Orchard joins the show to talk about her new book, “Take Control of Shortcuts”, and the state of automation on iOS and MacOS.

Mariana Castañeda compartió algunos recuerdos en 6AM de su padre, el reconocido productor de Caracol Radio que trabajó de la mano de históricos como Yamid Amat y Darío Arizmendi

El gobernador del Vichada, Álex Benito habló en 6AM sobre la caída del helicóptero de la Fuerza Aérea, que enluta nuevamente al país.

Ante los acontecimientos que afectan a esta ciudad, se confirmó que Nelson Quijano fue el primer colombiano fallecido por las inundaciones. Su hermano habló en 6AM.

Sylwia Struk
Dec 28, 2020; 0:RA119.001766v1-mcp.RA119.001766
Research

The F-box protein MORE AXILLARY GROWTH 2 (MAX2) is a central component in the signaling cascade of strigolactones (SLs) as well as of the smoke derived karrikins (KARs) and the so far unknown endogenous KAI2 ligand (KL). The two groups of molecules are involved in overlapping and unique developmental processes, and signal-specific outcomes are attributed to perception by the paralogous α/β-hydrolases DWARF14 (D14) for SL and KARRIKIN INSENSITIVE 2/ HYPOSENSITIVE TO LIGHT (KAI2/HTL) for KAR/KL. Additionally, depending on which receptor is activated, specific members of the SUPPRESSOR OF MAX2 1 (SMAX1) – LIKE (SMXL) family control KAR/KL and SL responses. As proteins that function in the same signal transduction pathway often occur in large protein complexes, we aimed at discovering new players of the MAX2, D14 and KAI2 protein network by tandem affinity purification using Arabidopsis cell cultures. When using MAX2 as a bait, various proteins were co-purified among which general components of the Skp1-Cullin-F-box complex and members of the CONSTITUTIVE PHOTOMORPHOGENIC 9 signalosome. Here, we report the identification of a novel interactor of MAX2, a type 5 serine/threonine protein phosphatase, designated PHYTOCHROME-ASSOCIATED PROTEIN PHOSPHATASE 5 (PAPP5). Quantitative affinity purification pointed at PAPP5 as being more present in KAI2 rather than D14 protein complexes. In agreement, mutant analysis suggests that PAPP5 modulates KAR/KL-dependent seed germination in suboptimal conditions and seedling development. Additionally, a phosphopeptide enrichment experiment revealed that PAPP5 might dephosphorylate MAX2 in vivo independently of the synthetic strigolactone analog, rac-GR24. Together, by analyzing the protein complexes to which MAX2, D14 and KAI2 belong, we revealed a new MAX2 interactor, PAPP5, that might act through dephosphorylation of MAX2 to control mainly KAR/KL- related phenotypes and, hence, provide another link with the light pathway.

The NRA

How did the supermassive black holes we’re now seeing in the early universe get so big so fast? Astrophysicist Sophie Koudmani is using sophisticated galaxy simulations to figure it out

The Large Hadron Collider is testing entanglement in a whole new energy range, probing the meaning of quantum theory – and the possibility that an even stranger reality lies beneath