by Jon Rappoport www.nomorefakenews.com The medical system kills 225,000 people a year. (Starfield, JAMA, July 26, 2000, "Is US health really the best in the world?") "In principle, gene therapy is a medical miracle waiting to happen ... after 17 years of trying, scientists are still struggling to make gene therapy work. Complications include rejection of DNA carriers ... [and] new genes end up where they shouldn't, or behave unpredictably." ("Gene Therapy: Is Death and Acceptable Risk?", Wired, Brandon Keim, August 30, 2007) MARCH 28, 2012 - In discussing Matrix Science, I'm reminded of Philip Dick's sensational novel, Lies, Inc. It proposes an invention that can teleport humans light-years to a planet where a better way of life exists. The author then spends the rest of the book deconstructing this utopian legend and revealing the truth and the titanic power-grab that sit behind it. Then there is HG Well's 1933 classic novel, The Shape of Things to Come, in which a world exhausted by war and economic collapse turns to a Global State as the only possible solution, after all other solutions have historically failed. This new ruling authority is based on Science. All religions are crushed. Education is designed to teach every child how to become a genius/global citizen. Eventually, the State withers away and is of course replaced by a spontaneous Utopia. Science/technology: the final all-encompassing answer. A significant aspect of Matrix propaganda revolves around myths about how human behavior can be transformed. Transformed through advances in biology and chemistry. Populations are being trained to expect these momentous changes. A major selling point: no effort is required. Just ingest this tablet. Accept this new gene. All will be done for you by experts. Technocrats will design the future so you will fit into it happily. The technocratic wing of Globalism has clout. It promises management of the planet through science, and who can argue with science? Central Planning will ensure proper benefits for all. My late friend and colleague, hypnotherapist Jack True, once told me in an interview:...

te koop..een zeer mooi feeder visstation van het merk matrix.het is 1 klein jaartje oud maar in super mooie staat.er zitten heel veel extra bij.mocht je interesse hebben stuur ik graag wat foto s naar u.gr smeets

"There is no spoon." Steve and Christian watched the classic sci film, "The Matrix." The guys discuss what it means to be human, the nature of reality, free will, and taking the "red pill." We're also shining a light on the Saint Haralambos Agape Grocery, which has distributed over 16 tons of groceries to the public since in the last few months. It's one of many outreach programs the parish offers to the wider community. Learn more on the parish website: saintharalambosgoc.org. In our next episode, we'll get in the holiday spirit and dig into the Netflix movies "The Christmas Chronicles."

Dn. Rico Monge joins Steve and Christian to discuss "Matrix Resurrections." Spoilers ahead! They explore humanity, freedom, and love.

Washington – A new OSHA fact sheet provides guidance on selecting personal protective equipment for workers who may be exposed to Ebola.

Recent advances in quantum crystallography have shown that, beyond conventional charge density refinement, a one-electron reduced density matrix (1-RDM) satisfying N-representability conditions can be reconstructed using jointly experimental X-ray structure factors and directional Compton profiles (DCP) through semidefinite programming. So far, such reconstruction methods for 1-RDM, not constrained to idempotency, have been tested only on a toy model system (CO2). In this work, a new method is assessed on crystalline urea [CO(NH2)2] using static (0 K) and dynamic (50 K) artificial experimental data. An improved model, including symmetry constraints and frozen core-electron contribution, is introduced to better handle the increasing system complexity. Reconstructed 1-RDMs, deformation densities and DCP anisotropy are analysed, and it is demonstrated that the changes in the model significantly improve the reconstruction quality, even when there is insufficient information and data corruption. The robustness of the model and the strategy are thus shown to be well adapted to address the reconstruction problem from actual experimental scattering data.

Rapid growth of the snack brand called for an upgrade in its packaging technology.

Gavan introduces FaTRIX alternative protein-enriched fat ingredient that butters up chef pastries and slashes saturated fat by 80%.

This 8x8 8K matrix switcher/scaler enables users to manage, control, and route eight HDMI 2.1 sources and eight 8K displays from one device.

Travel Planning Simplified. We search over 200 airlines and countless sites instantaneously and offer the lowest fare, in one place. Compare flights and hotels easily. OA!

As a special bonus, we have unlocked the first of two bonus episodes this month on the RIP a Livecast Patreon page, where we go through our thoughts on all […]

The 2022 Ethiopia Social Accounting Matrix (SAM) follows IFPRI's Standard Nexus SAM approach, by focusing on consistency, comparability, and transparency of data. The Nexus SAMs available on IFPRI's website separates domestic production into 42 activities. Factors are disaggregated into labor, agricultural land, and capital, with labor further disaggregated across three education-based categories. The household account […] Source: IFPRI Ethiopia: Ethiopia Strategy Support Program

Show attendees can see how ProMach’s new Pet Care Solutions Team is bringing seamless processing and packaging solutions to the pet care industry.

Camilo Sanchez will head the newly formed Flexible Packaging Group, which offers a single point of contact for both Bartelt and Matrix packaging technologies.

Padre e hijo, que ya han coincidido en pretemporada, lograrán algo inédito en la NBA mientras se disparan las dudas sobre el rendimiento del joven. Leer

Dana Laake and her special guest Dr. Michael Murray will discuss his new book, The Longevity Matrix – How to Live Better, Stronger, and Longer.

The post The new book, The Longevity Matrix – How to Live Better, Stronger, and Longer first appeared on Federal News Network.

Pop culture, and especially science fiction, has played host to several of philosophy’s biggest questions that can trace their origins back thousands of years, according to David Chalmers, philosopher and author of Reality+.

Marcelo Campos, Matthew Jenssen, Marcus Michelen and Julian Sahasrabudhe
J. Amer. Math. Soc. 38 (), 179-224.
Abstract, references and article information

The extracellular matrix encompasses a reservoir of bioactive macromolecules that modulates a cornucopia of biological functions. A prominent body of work posits matrix constituents as master regulators of autophagy and angiogenesis and provides molecular insight into how these two processes are coordinated. Here, we review current understanding of the molecular mechanisms underlying hyaluronan and HAS2 regulation and the role of soluble proteoglycan in affecting autophagy and angiogenesis. Specifically, we assess the role of proteoglycan-evoked autophagy in regulating angiogenesis via the HAS2-hyaluronan axis and ATG9A, a novel HAS2 binding partner. We discuss extracellular hyaluronan biology and the post-transcriptional and post-translational modifications that regulate its main synthesizer, HAS2. We highlight the emerging group of proteoglycans that utilize outside-in signaling to modulate autophagy and angiogenesis in cancer microenvironments and thoroughly review the most up-to-date understanding of endorepellin signaling in vascular endothelia, providing insight into the temporal complexities involved.

The brain's extracellular matrix (ECM) regulates neuronal plasticity and animal behavior. ECM staining shows a net-like structure around a subset of neurons, a ring-like structure at the nodes of Ranvier, and diffuse staining in the interstitial matrix. However, understanding the structural features of ECM deposition across various neuronal types and subcellular compartments remains limited. To visualize the organization pattern and assembly process of the hyaluronan-scaffolded ECM in the brain, we fused a HaloTag to hyaluronan proteoglycan link protein 1, which links hyaluronan and proteoglycans. Expression or application of the probe in primary rat neuronal cultures enables us to identify spatial and temporal regulation of ECM deposition and heterogeneity in ECM aggregation among neuronal populations. Dual-color birthdating shows the ECM assembly process in culture and in vivo. Sparse expression in mouse brains of either sex reveals detailed ECM architectures around excitatory neurons and developmentally regulated dendritic ECM. Our study uncovers extensive structural features of the brain's ECM, suggesting diverse roles in regulating neuronal plasticity.

A STING (stimulator of interferon genes) agonist GSK3996915 under investigation in early discovery for hepatitis B was orally dosed to a mouse model for understanding the parent drug distribution in liver, the target organ. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) was used to quantify the distribution of GSK3996915 in liver collected from mice administered a single oral dose at 90 mg/kg. GSK3996915 was detected with a zonal distribution localized in the portal triad and highly concentrated in the main bile ducts, indicating clearance through biliary excretion. High spatial resolution imaging showed the distribution of the parent drug localized to the cellular populations in the sinusoids, including the Kupffer cells. Additionally, a series of drug-related metabolites were observed to be localized in the central zones of the liver. These results exemplify the potential of utilizing MALDI IMS for measuring not only quantitative drug distribution and target exposure but also drug metabolism and elimination in a single suite of experiments.

UCEED 2023: The Under Graduate Common Entrance Test for Design (UCEED) 2023 seat matrix has been released for the Bachelor of Design programme. The category wise distribution of the available seats at IIT Bombay, IIT Delhi, IIT Guwahati, IIT Hyderabad and

A clip from the documentary "A Glitch in the Matrix."

Inter-α-inhibitor is a proteoglycan essential for mammalian reproduction and also plays a less well-characterized role in inflammation. It comprises two homologous “heavy chains” (HC1 and HC2) covalently attached to chondroitin sulfate on the bikunin core protein. Before ovulation, HCs are transferred onto the polysaccharide hyaluronan (HA) to form covalent HC·HA complexes, thereby stabilizing an extracellular matrix around the oocyte required for fertilization. Additionally, such complexes form during inflammatory processes and mediate leukocyte adhesion in the synovial fluids of arthritis patients and protect against sepsis. Here using X-ray crystallography, we show that human HC1 has a structure similar to integrin β-chains, with a von Willebrand factor A domain containing a functional metal ion-dependent adhesion site (MIDAS) and an associated hybrid domain. A comparison of the WT protein and a variant with an impaired MIDAS (but otherwise structurally identical) by small-angle X-ray scattering and analytical ultracentrifugation revealed that HC1 self-associates in a cation-dependent manner, providing a mechanism for HC·HA cross-linking and matrix stabilization. Surprisingly, unlike integrins, HC1 interacted with RGD-containing ligands, such as fibronectin, vitronectin, and the latency-associated peptides of transforming growth factor β, in a MIDAS/cation-independent manner. However, HC1 utilizes its MIDAS motif to bind to and inhibit the cleavage of complement C3, and small-angle X-ray scattering–based modeling indicates that this occurs through the inhibition of the alternative pathway C3 convertase. These findings provide detailed structural and functional insights into HC1 as a regulator of innate immunity and further elucidate the role of HC·HA complexes in inflammation and ovulation.

Using the typical WC–Co cemented carbide as an example, the interactions of dislocations within the ceramic matrix and the binder metal, as well as the possible cooperation and competition between the matrix and binder during deformation of the nanocrystalline cermets, were studied by molecular dynamics simulations. It was found that at the same level of strain, the dislocations in Co have more complex configurations in the cermet with higher Co content. With loading, the ratio between mobile and sessile dislocations in Co becomes stable earlier in the high-Co cermet. The strain threshold for the nucleation of dislocations in WC increases with Co content. At the later stage of deformation, the growth rate of WC dislocation density increases more rapidly in the cermet with lower Co content, which exhibits an opposite tendency compared with Co dislocation density. The relative contribution of Co and WC to the plasticity of the cermet varies in the deformation process. With a low Co content, the density of WC dislocations becomes higher than that of Co dislocations at larger strains, indicating that WC may contribute more than Co to the plasticity of the nanocrystalline cermet at the final deformation stage. The findings in the present work will be applicable to a large variety of ceramic–metal composite materials.