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Wrestlemania 31 weekend: Jim Ross continues an epic career of storytelling

Jerry "The King" Lawler with Jim Ross.; Credit: WWE

Mike Roe

Jim Ross is the most famous pro wrestling play-by play commentator of all time. He's a native Californian, but grew up in Oklahoma and took his trademark drawl into doing commentary. He's worked in wrestling for more than 40 years, calling matches on shows seen by millions of people around the world.

This weekend, he's in the Bay Area for Wrestlemania weekend (the first Wrestlemania in Northern California, and the first in California in 10 years). Ross no longer commentates for WWE, but he's still a storyteller, online and in person. He hosts regular live storytelling shows with stories from his decades-long career and a bit of comedy, along with a live guest, and he also has a huge online presence including a podcast that went to number one in sports its first week out.

Ross has been watching wrestling since he was a kid.

"My dad wasn't a big fan of it. He missed the point. The point is not whether it's real or if it's staged. The point is, are you entertained by it, or not? And I was," Ross said.

He's been at ringside for numerous historic matches, helping the wrestlers to tell their stories ever since he got his first job in wrestling out of college at 22.

"The greater the star, the easier it is to tell their story," Ross said. "Those participants make music. They make different kinds of music, and the announcers, the broadcasters, have to be able to provide the adequate lyric to the competitors' music."

Ross's voice is so powerful that it's become a meme online to pair his voice with another dramatic footage, from sports and beyond — you can even find it paired with dramatic moments from shows like "Breaking Bad" and "Game of Thrones." Ross says that the first time he saw someone do that was with a hit by Michigan running back Jadaveon Clowney, a video which went viral and sparked others to do likewise.

The JR Treatment

"I get sent these memes all the time. 'Hey JR, check this one out.' Or people will say, somebody will make a great dunk at an NBA game, and somebody will say 'I can't wait to see this get the JR treatment.' And now there are major sports websites that will send out a tweet, 'Here's a great play from Sunday's 49er-Charger game that's got the JR treatment.' So now it's got a name. 'The JR Treatment.'"

Those viral videos have even helped him land new commentating roles since leaving WWE. He did a call of a fight between NASCAR drivers for the Daytona 500 for a special pre-show video, and it's led to him having opportunities in traditional sports.

"It's been done in boxing, and MMA. Believe it or not, I've gotten feelers that we're entertaining now from a variety of combat sports entities that actually heard what my call would sound like doing their product," Ross said. "It had my tone, had my inflection, had my level of enthusiasm."

Ross also played a huge role behind the scenes, working as WWE's executive vice president of talent and signing future stars like the Rock, Mick Foley and more. He says that Mick Foley's match against the Undertaker in 1998's Hell in a Cell match was his most memorable to call.

"I have people walk up to me and start quoting my commentary when Undertaker threw Foley off the Hell in a Cell, this massive cage with a roof on it, that was about 17 feet high from the roof to the floor," Ross said. "It looked like no human being, quite honestly, could survive that fall. You don't practice falls like that in wrestling school."

Ross has managed to stay relevant with the help of a popular podcast and 1.3 million followers on Twitter, where he regularly dispenses his thoughts on wrestling and beyond. He started doing that podcast after being lobbied to do it by "Stone Cold" Steve Austin, and continues to try new things.

"I was very reluctant to engage in social media, and primarily because we sometimes get set in our ways, especially the older we get," Ross said. "But change, for any of us, in any walk of life, whether it's your diet, it's your relationships, the way you approach your job, or any changes that you need to affect, whether it's on doctor's orders, your significant other's suggestions — change is not always a negative thing. So I got on Twitter, and then Twitter connected me to so many people."

While some may feel that pro wrestling, given its predetermined results, doesn't need real athletes, Ross disagrees and says there are plenty of reasons to want real athletes.

"They're competitive. They don't want to be on the second team. They want to be in the game. And they've been in that mindset since some of them were in little league, or Pop Warner football, or elementary school wrestling, or whatever it may be."

He says they also understand how to be coached and how to play well with others, as well as handling the bumps and bruises that come with the territory and the difficult travel schedule.

"I don't know that anybody in any entity, unless you're the most well-traveled comedian or entertainer, has that. Because the thing about pro wrestling is it doesn't have an off-season, so you don't get a chance to really go recharge your batteries. You've got to maintain that competitive edge to survive."

Ross says there's one match he wishes he had another shot at calling: Ric Flair's retirement match against Shawn Michaels at Wrestlemania 24 in Orlando at the Citrus Bowl. While Ross has traditionally been a play-by-play commentator, that night he was assigned to be a color commentator, which gave him some different challenges.

"I thought I had great stories to tell because of my relationship with Ric — I've known him for 25 years — and I didn't think that I contributed as much to that match from an emotional standpoint as I could. I was obligated to get in soundbites and get in, get out," Ross said. "That's the biggest match at the biggest stage, and I love both those guys, and I really wanted to be extra special that night, and I just don't know in my heart that we got there."

He says California has its own wrestling legacy to be proud of. The California Wrestlemania match that Ross says he'll always remember: Bret Hart versus Shawn Michaels at Wrestlemania 12 in Anaheim, where two now wrestling legends wrestled for more than an hour.

He also thinks the economics of Wrestlemania make a lot of sense for whichever city hosts it, thanks to the travelers it draws in from around the world. Cities now bid to try to bring in Wrestlemania, Ross says. With Los Angeles gearing up to build a new stadium, Ross has a Wrestlemania prediction for that stadium.

"I will bet you money — I will bet you some of my barbecue sauce — if L.A. builds a stadium, that Wrestlemania will be one of the first non-football events in that stadium. And they will sell it out. They'll fill every seat. And it'll be great for the city, and the businesses of Los Angeles.

Ross says that what made him a great broadcaster is the same thing that can make someone a success in wrestling or anywhere else — most importantly, don't talk down to your audience.

"You have to be a fan of the genre, or a fan of the game, and you have to be willing to prepare and be ready for your broadcast," Ross said. "You have to be willing to tell the story that the average fan — not the hardcore fan, but the average, casual fan can understand and relate to. ... You know, we're storytellers, and some people are just natural-born storytellers."

Ross plans to continue telling stories for the foreseeable future, on stage, online, calling matches in the legit sports world and wherever else his life takes him. He's even gotten into acting — you can see him in the new film "What Now."

"I think retirement is overblown. How many days can you go fishing? How many rounds of golf can you play?" Ross said. "I had the idea when I left WWE after 21 years, I'm going to reinvent myself. I'm not going to become a trivia answer. ... I don't think you're going to read anywhere, anytime soon, that Jim Ross has finally retired — until you read my eulogy."

Listen to the audio for the full hour-long interview with Jim Ross, talking his career past, present and future — along with the origins of his signature barbecue sauce.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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WWE looks to springboard from Wrestlemania 31 into new audiences

Brock Lesnar after losing his championship in the main event of Wrestlemania 31.; Credit: WWE

Mike Roe

World Wrestling Entertainment held their annual Wrestlemania show last weekend in Northern California, the culmination of another year's worth of spectacle. According to the company, it was their highest grossing event of all-time, drawing $12.6 million, with an official attendance placing it fifth on their list of all-time crowds for the event. The show was headlined by former UFC Heavyweight Champion Brock Lesnar going up against up-and-coming star (and a relative of Dwayne "The Rock" Johnson) Roman Reigns.

WWE Network

It comes at a time when the company has embarked on a new way of making money: their over-the-top online programming provider, the WWE Network, where fans can pay $9.99 a month to see programming including what formerly used to cost $45 for most shows and $60 for Wrestlemania. They're one year in now on gambling that enough fans will want the Network that it will ultimately make them more money in the long-term, despite losing that pay-per-view revenue. Wall Street doesn't appear to be buying it — after announcing the day after Wrestlemania that they'd hit 1.3 million subscribers, WWE's stock took a significant loss.

"The point is not whether it's real or if it's staged. The point is, are you entertained by it, or not?" former WWE announcer Jim Ross told KPCC in an interview. WWE is looking for more fans to be entertained enough to plunk down $9.99 for all the pro wrestling content they want.

NXT

They're also in a transitional period with their audiences. They've launched a new show that's only on the Network called "NXT," turning their minor league into a program targeting hardcore pro wrestling fans with a different style of show than the more family-targeted "Raw" and "Smackdown." It's also where they groom potential future stars, many of whom seem to break the mold of some of the traditional stars on WWE's main roster.

They're signing up talent that's been getting buzz on the independent circuits, trying to create their own underground movement that hopefully spells money, and taking the NXT brand on tour for the first time. On the Raw after Wrestlemania, several NXT stars made their debut on the main roster. That follows a sell-out crowd (albeit at a smaller 5,000 seat venue) on the Friday night before Wrestlemania for a non-televised NXT show.

Give Divas a chance

WWE also faces cultural forces pushing them in new directions, including a difference in how society deals with gender. When WWE executive Stephanie McMahon, daughter of the famed Vince McMahon, tweeted in support of Patricia Arquette's speech calling for greater equality for women at the Academy Awards, one of their own wrestlers, AJ Lee, responded by publicly calling Stephanie McMahon out on Twitter for not promoting the women in her own company equally and paying them less than the male stars.

AJ tweet 1

AJ tweet 2

Of course, the women in the company aren't given the same prominence as the men in part because it's felt that they won't make the company as much money. Still, it forced WWE's hand and Stephanie McMahon and the company as a whole publicly embraced the idea of giving the women (who WWE brands as "divas") a chance with the Give Divas A Chance movement (and accompanying trending hashtag).

What's next

The women have been promoted nearly equal to the men in that underground NXT league, but only time will tell if it continues to trickle upward. Wrestlemania didn't seem to show huge promise of that happening, with the one women's match of the show only getting a few minutes in the ring. However, the show also included a high-profile storyline with UFC female fighter and champion Ronda Rousey alongside the Rock, going up against Stephanie McMahon and Triple H, so there appears to be the room for women in prominent positions when they have the right storyline.

Whether WWE is able to wade through these forces of change to make more money — and perhaps regain some of the cultural currency that they've lost since becoming a monopoly and purchasing their top competition in 2001 — remains to be seen. They've stayed relatively steady despite a challenge from UFC, which many see as being what pro wrestling would be like if WWE didn't present fictional  They'll have to hope that giving new stars, including "divas," a chance will take them to another level.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Romania approves purchase of 32 F-35s

Romanian senators on Wednesday gave final approval to a bill authorising contracts to purchase the world's most advanced fighter aircraft, the F-35, with the first delivery expected in 2031. In this case, the Senate is the decision-making body, and the law now goes to the president for…




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Athlete Lineup Announced for 2025 Red Bull Hardline Tasmania



Asa Vermette, Vali Holl, Sam Hill, Erice Van Leuven, and Gee Atherton are all on the list.
( Photos: 5, Comments: 76 )




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Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety

RSC Med. Chem., 2024, 15,3837-3852
DOI: 10.1039/D4MD00426D, Research Article
Abdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. Bednarski
Structure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safety
The content of this RSS Feed (c) The Royal Society of Chemistry




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WrestleMania 31 was the thirty-first annual WrestleMania professional wrestling pay-per-view (PPV) event produced by WWE. It took place on March 29, 2015, at Levi's Stadium in Santa Clara, California.

https://en.wikipedia.org/wiki/WrestleMania_31





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Fr. Seraphim gives a short update.




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Our Venerable Father Demetrius of Basarabov (Romania) (13th c.)

He was born early in the thirteenth century to a peasant family in the village of Basarov, then part of Bulgaria. Even in childhood, he gave himself to fasting and prayer. Once, walking across a field, he accidentally stepped on a bird's nest in the grass, killing the young birds. He was so filled with remorse that he went barefoot for three years, winter and summer, in penance. When he was grown he joined a monastery and, after a few years of community life, received a blessing to dwell in a cave near the River Lom. After many years of solitary struggle, he reposed in his cave. Three hundred years passed, during which all memory of the simple ascetic was lost. Then, one Spring the river flooded the cave and carried off Demetrius' body, which had lain incorrupt in the cave for centuries. The body was carried downstream and buried in gravel. Another hundred years went by, and the Saint appeared in a dream to a paralyzed girl, telling her to ask her parents to take her to the river bank, where she would be healed. The family, along with many clergy and villagers, went to a spot where some local people had earlier seen an unexplained light. They dug and soon unearthed the still-incorrupt and radiant body of St Demetrius, by which the girl was instantly healed. A church was built in the village of Basarabov to honor the precious relics, and through the years the Saint worked many miracles there.   In 1774, during the Russian-Turkish war, General Peter Saltikov ordered the holy relics taken to Russia so that they would not be desecrated by the Turks. When the relics came to Bucharest, a pious Christian friend of the General begged him not to deprive the country of one of its most precious saints; so the General took only one of the Saint's hands, sending it to the Kiev Caves Lavra. Saint Demetrius' body was placed in the cathedral of Bucharest, where it has been venerated ever since. Every year on October 27, a three-day festival is held in the Saint's honor, attended by crowds of the faithful.




mania

Our Venerable Father Demetrius of Basarabov (Romania) (13th c.)

He was born early in the thirteenth century to a peasant family in the village of Basarov, then part of Bulgaria. Even in childhood, he gave himself to fasting and prayer. Once, walking across a field, he accidentally stepped on a bird's nest in the grass, killing the young birds. He was so filled with remorse that he went barefoot for three years, winter and summer, in penance. When he was grown he joined a monastery and, after a few years of community life, received a blessing to dwell in a cave near the River Lom. After many years of solitary struggle, he reposed in his cave. Three hundred years passed, during which all memory of the simple ascetic was lost. Then, one Spring the river flooded the cave and carried off Demetrius' body, which had lain incorrupt in the cave for centuries. The body was carried downstream and buried in gravel. Another hundred years went by, and the Saint appeared in a dream to a paralyzed girl, telling her to ask her parents to take her to the river bank, where she would be healed. The family, along with many clergy and villagers, went to a spot where some local people had earlier seen an unexplained light. They dug and soon unearthed the still-incorrupt and radiant body of St Demetrius, by which the girl was instantly healed. A church was built in the village of Basarabov to honor the precious relics, and through the years the Saint worked many miracles there.   In 1774, during the Russian-Turkish war, General Peter Saltikov ordered the holy relics taken to Russia so that they would not be desecrated by the Turks. When the relics came to Bucharest, a pious Christian friend of the General begged him not to deprive the country of one of its most precious saints; so the General took only one of the Saint's hands, sending it to the Kiev Caves Lavra. Saint Demetrius' body was placed in the cathedral of Bucharest, where it has been venerated ever since. Every year on October 27, a three-day festival is held in the Saint's honor, attended by crowds of the faithful.




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Our Venerable Father Demetrius of Basarabov (Romania) (13th c.) - October 27th

He was born early in the thirteenth century to a peasant family in the village of Basarov, then part of Bulgaria. Even in childhood, he gave himself to fasting and prayer. Once, walking across a field, he accidentally stepped on a bird's nest in the grass, killing the young birds. He was so filled with remorse that he went barefoot for three years, winter and summer, in penance. When he was grown he joined a monastery and, after a few years of community life, received a blessing to dwell in a cave near the River Lom. After many years of solitary struggle, he reposed in his cave. Three hundred years passed, during which all memory of the simple ascetic was lost. Then, one Spring the river flooded the cave and carried off Demetrius' body, which had lain incorrupt in the cave for centuries. The body was carried downstream and buried in gravel. Another hundred years went by, and the Saint appeared in a dream to a paralyzed girl, telling her to ask her parents to take her to the river bank, where she would be healed. The family, along with many clergy and villagers, went to a spot where some local people had earlier seen an unexplained light. They dug and soon unearthed the still-incorrupt and radiant body of St Demetrius, by which the girl was instantly healed. A church was built in the village of Basarabov to honor the precious relics, and through the years the Saint worked many miracles there.   In 1774, during the Russian-Turkish war, General Peter Saltikov ordered the holy relics taken to Russia so that they would not be desecrated by the Turks. When the relics came to Bucharest, a pious Christian friend of the General begged him not to deprive the country of one of its most precious saints; so the General took only one of the Saint's hands, sending it to the Kiev Caves Lavra. Saint Demetrius' body was placed in the cathedral of Bucharest, where it has been venerated ever since. Every year on October 27, a three-day festival is held in the Saint's honor, attended by crowds of the faithful.




mania

Our Venerable Father Demetrius of Basarabov (Romania) (13th c.)

He was born early in the thirteenth century to a peasant family in the village of Basarov, then part of Bulgaria. Even in childhood, he gave himself to fasting and prayer. Once, walking across a field, he accidentally stepped on a bird's nest in the grass, killing the young birds. He was so filled with remorse that he went barefoot for three years, winter and summer, in penance. When he was grown he joined a monastery and, after a few years of community life, received a blessing to dwell in a cave near the River Lom. After many years of solitary struggle, he reposed in his cave. Three hundred years passed, during which all memory of the simple ascetic was lost. Then, one Spring the river flooded the cave and carried off Demetrius' body, which had lain incorrupt in the cave for centuries. The body was carried downstream and buried in gravel. Another hundred years went by, and the Saint appeared in a dream to a paralyzed girl, telling her to ask her parents to take her to the river bank, where she would be healed. The family, along with many clergy and villagers, went to a spot where some local people had earlier seen an unexplained light. They dug and soon unearthed the still-incorrupt and radiant body of St Demetrius, by which the girl was instantly healed. A church was built in the village of Basarabov to honor the precious relics, and through the years the Saint worked many miracles there.




mania

Our Venerable Father Demetrius of Basarabov (Romania) (13th c.)

He was born early in the thirteenth century to a peasant family in the village of Basarov, then part of Bulgaria. Even in childhood, he gave himself to fasting and prayer. Once, walking across a field, he accidentally stepped on a bird's nest in the grass, killing the young birds. He was so filled with remorse that he went barefoot for three years, winter and summer, in penance. When he was grown he joined a monastery and, after a few years of community life, received a blessing to dwell in a cave near the River Lom. After many years of solitary struggle, he reposed in his cave. Three hundred years passed, during which all memory of the simple ascetic was lost. Then, one Spring the river flooded the cave and carried off Demetrius' body, which had lain incorrupt in the cave for centuries. The body was carried downstream and buried in gravel. Another hundred years went by, and the Saint appeared in a dream to a paralyzed girl, telling her to ask her parents to take her to the river bank, where she would be healed. The family, along with many clergy and villagers, went to a spot where some local people had earlier seen an unexplained light. They dug and soon unearthed the still-incorrupt and radiant body of St Demetrius, by which the girl was instantly healed. A church was built in the village of Basarabov to honor the precious relics, and through the years the Saint worked many miracles there.




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Treasures of Romania 2.0

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La Germania divisa tra etica e diritto

È giusto considerare Puigdemont alla stregua di un terrorista o di un ladro, perché di questo si tratta, consegnandolo nelle braccia di un sistema che potrebbe condannarlo a 30 anni di carcere?



CORRIERE DELLA SERA
26-03-2018
 
PAOLO VALENTINO
 
È una classica contraddizione weberiana, tra etica dei valori e etica della responsabilità, quella che si trova a fronteggiare la Germania, con l’arresto del leader catalano Puigdemont, in esecuzione di un mandato di cattura europeo emesso dalle autorità spagnole. La Repubblica federale, come tutti i Paesi della Ue, ha sottoscritto un meccanismo basato sulla reciproca fiducia, in grado di rendere più semplici le procedure di estradizione all’interno dello spazio comunitario. Come spiega oggi nell’intervista al Corriere il professor Martin Heger, il mandato di cattura europeo implica che ogni Paese si fidi dello Stato di diritto di un altro e viceversa. Per questo, quando viene emesso per una delle 32 categorie di reati gravi previste, comporta una procedura squisitamente giuridica, priva cioè di influenze politiche.

Responsabilità dei giudici dello Schleswig-Hollstein, il Land dove il leader secessionista è stato intercettato su segnalazione dei servizi spagnoli e fermato, è dunque di verificare che i reati contestati dai colleghi madrileni a Puigdemont siano compatibili con quelli previsti dal codice penale tedesco e se del caso concedere l’estradizione. È poco probabile però, secondo gli esperti, che questa venga decisa sulla base dell’accusa di ribellione, visto che il reato analogo in Germania, quello di «alto tradimento», è legato indissolubilmente alla violenza o all’incitazione alla violenza. Puigdemont non ha mai lanciato alcun appello alle armi, a meno di non considerare tale l’appello al voto. È invece più verosimile, ancorché ugualmente controverso, che l’accusa buona per estradarlo si riveli alla fine quella di appropriazione indebita di denaro pubblico, usato dall’ex presidente catalano per organizzare una consultazione considerata illegale e in violazione dell’ordine costituzionale spagnolo.
 
Fin qui l’etica della responsabilità, appunto, cui difficilmente la Germania potrà sottrarsi nel rispetto delle regole europee liberamente sottoscritte e della fiducia dovuta ai partner. «La Spagna è uno Stato di diritto», ha ribadito ieri il portavoce del governo tedesco, Steffen Seibert. I valori sono un’altra cosa, specialmente per un Paese ad altissima sensibilità democratica e garantista come in ragione della sua storia è la Repubblica Federale. Forse con una punta di esagerazione, la Sueddeutsche Zeitung ha toccato il nervo scoperto di questa vicenda, definendo Puigdemont il «primo prigioniero politico» della Germania.

Sarà possibile per il governo tedesco ignorare questa semplice verità e trincerarsi dietro la procedura tecnica? È giusto considerare Puigdemont alla stregua di un terrorista o di un ladro, perché di questo si tratta, consegnandolo nelle braccia di un sistema che potrebbe condannarlo a 30 anni di carcere? «Il mandato di cattura europeo non è uno strumento per regolare questioni di politica interna con l’aiuto di pubblici ministeri stranieri», commenta Wolfgang Janisch sul giornale bavarese. Né la fiducia reciproca su cui si fonda l’intero costrutto può essere cieca, ignorando il sospetto di persecuzione politica che accompagna l’azione delle autorità centrali spagnole contro i leader del movimento catalano. Perché se è vero che la secessione catalana non è legale, né costituzionale, è difficile per la Germania come per ogni altro Paese accettare che Madrid tenti di sconfiggere un movimento di massa democratico solo con la forza o il codice penale esteso all’intero territorio comunitario grazie al mandato di cattura europeo. Quanto sia sanabile la contraddizione weberiana tra responsabilità e principi è impossibile dire. Forse non lo è. E questo pone il nuovo governo tedesco in una posizione molto complicata, tanto più alla luce degli ottimi rapporti da sempre intercorsi tra Angela Merkel e Mariano Rajoy. Il caso è già politico. I Verdi suggeriscono che Berlino promuova un negoziato tra il governo di Madrid e i leader catalani, affidando la mediazione alla Commissione europea.

Una cosa certa. Nella sua improbabilità, Puigdemont ha internazionalizzato la vicenda catalana, confermando che nella Ue non esistono più crisi locali, che ogni battito d’ali provoca ripercussioni profonde e che farebbe bene l’Europa a prenderne atto.
 




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How Security Dealers Can Get in on Holiday Shopping Mania

Offering Black Friday and holiday season shopping deals aren’t just for the retail industry. Security dealers can get in on the action too. 




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Childhood and belonging over time: narratives of identity across generations on Tasmania's east coast.

Children's Geographies; 02/01/2023
(AN 163249008); ISSN: 14733285
Academic Search Premier





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Cocrystals of a coumarin derivative: an efficient approach towards anti-leishmanial cocrystals against MIL-resistant Leishmania tropica

Leishmaniasis is a neglected parasitic tropical disease with numerous clinical manifestations. One of the causative agents of cutaneous leishmaniasis (CL) is Leishmania tropica (L. tropica) known for causing ulcerative lesions on the skin. The adverse effects of the recommended available drugs, such as amphotericin B and pentavalent antimonial, and the emergence of drug resistance in parasites, mean the search for new safe and effective anti-leishmanial agents is crucial. Miltefosine (MIL) was the first recommended oral medication, but its use is now limited because of the rapid emergence of resistance. Pharmaceutical cocrystallization is an effective method to improve the physicochemical and biological properties of active pharmaceutical ingredients (APIs). Herein, we describe the cocrystallization of coumarin-3-carb­oxy­lic acid (CU, 1a; 2-oxobenzo­pyrane-3-carb­oxy­lic acid, C10H6O4) with five coformers [2-amino-3-bromo­pyridine (1b), 2-amino-5-(tri­fluoro­methyl)-pyridine (1c), 2-amino-6-methyl­pyridine (1d), p-amino­benzoic acid (1e) and amitrole (1f)] in a 1:1 stoichiometric ratio via the neat grinding method. The cocrystals 2–6 obtained were characterized via single-crystal X-ray diffraction, powder X-ray diffraction, differential scanning calorimetry and thermogravimetric analysis, as well as Fourier transform infrared spectroscopy. Non-covalent interactions, such as van der Waals, hydrogen bonding, C—H⋯π and π⋯π interactions contribute significantly towards the packing of a crystal structure and alter the physicochemical and biological activity of CU. In this research, newly synthesized cocrystals were evaluated for their anti-leishmanial activity against the MIL-resistant L. tropica and cytotoxicity against the 3T3 (normal fibroblast) cell line. Among the non-cytotoxic cocrystals synthesized (2–6), CU:1b (2, IC50 = 61.83 ± 0.59 µM), CU:1c (3, 125.7 ± 1.15 µM) and CU:1d (4, 48.71 ± 0.75 µM) appeared to be potent anti-leishmanial agents and showed several-fold more anti-leishmanial potential than the tested standard drug (MIL, IC50 = 169.55 ± 0.078 µM). The results indicate that cocrystals 2–4 are promising anti-leishmanial agents which require further exploration.




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Data and analytics can be instrumental in shaping FMCG’s future: Nithya Subramanian, Kellogg Company

One of the primary ways data and analytics are influencing the FMCG industry is through demand forecasting and inventory management. By analyzing historical sales data, market trends, and external factors like seasonality and economic indicators, FMCG companies can optimize their production and supply chain processes.




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Develop Reliable Software Outsourcing Partnerships in Cluj, Romania

As a leading software company in Cluj, Romania, MoldoWEB is committed to delivering top-notch outsourcing services.




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SE-Radio Episode 340: Lara Hogan and Deepa Subramaniam on Revitalizing a Cross-Functional Product Organization

Travis Kimmel talks with Lara Hogan and Deepa Subramaniam about evidence-based tactics that product and engineering leaders can use to can use to diagnose problems that are holding back their teams, and build healthier, high-performing organizations.




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English Mania

The world has a common language to solve its common problems. So says Jay Walker in the following video. Here he explains why two billion people around the world are trying to learn the world's second langauage, English.




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Preview: Oracle Developer Live — Java Innovations: Venkat Subramaniam

Oracle Developer Live — Java Innovations: Building the Future Today: September 14 and 16

In this short conversation, Java developer Venkat Subramaniam previews his talk at the upcoming Oracle Developer Live — Java Innovations conference. The event is on September 14 and 16 and Venkat's session will be Making Use of Sealed Classes in Java. Don't miss it! Video.

Register for Oracle Developer Live — Java Innovations: Building the Future Today: September 14 and 16

Venkat Subramaniam, Founder Agile Developer, Inc.
https://twitter.com/venkat_s 

Podcast Host: Jim Grisanzio, Oracle Developer Relations
https://twitter.com/jimgris
https://developer.oracle.com/team/ 




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OracleDevLive Preview: Venkat Subramaniam on The Elegance of Pattern Matching in Modern Java

Venkat Subramaniam previews his upcoming session at Oracle Developer Live Java Innovations — The Elegance of Pattern Matching in Modern Java. The conversation was recorded via Zoom on Tuesday February 15, 2022.

Venkat Subramaniam, Founder, Agile Developer

@venkat_s on Twitter https://twitter.com/venkat_s

Background on Pattern Marching

JEP 305: Pattern Matching for instanceof (Preview)
Pattern Matching with Gavin Bierman — Inside Java Podcast 17
Pattern Matching in Java 17 and Beyond

Java Development & Community

OpenJDK https://openjdk.java.net/
Inside Java https://inside.java/
Dev.Java https://dev.java/
@java Twitter https://twitter.com/java

Duke's Corner Podcast

Jim Grisanzio, Host, Java Developer Relations
@jimgris on Twitter https://twitter.com/jimgris




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Volkswagen planea cerrar tres fábricas, miles de despidos y bajadas de sueldo en Alemania

El comité de empresa dice que ninguna de las plantas en el país está a salvo de ajustes. VW tiene en Alemania unos 120.000 empleados y 10 factorías. Leer





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Alemania fija para el 23 de febrero la celebración de las elecciones anticipadas

Olaf Scholz se someterá a una moción de confianza previsiblemente el 16 diciembre que perderá por estar en minoría Leer




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Hydrogeomorphic Risk Analysis Affecting Chalcolithic Archaeological Sites from Valea Oii (Bahlui) Watershed, Northeastern Romania An Interdisciplinary Approach

Location: Electronic Resource- 





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Popurrí internacional: elecciones en Alemania y crisis en Argentina

Panelistas analizaron un eventual ascenso de la socialdemocracia al poder; los retos del gobierno de Alberto Fernández y la polémica España-México por el perdón por la conquista.




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Convenios con Alemania, Congreso sigue sesionando y nuevas rutas aéreas

La Luciérnaga se enciende para hablar sobre la primera condena contra Mario Castaño, exsenador quién aceptó liderar una estructura criminal que se apropio de millonarios recursos del Estado. Por otro lado, Colombia y Alemania firmaron este viernes en Berlín un acuerdo que prevé analizar la producción de hidrógeno verde y sus derivados para su exportación hacia la nación europea. Asimismo, estuvimos en la feria más tradicional e importante de la región Caribe; La Feria de la Ganadería en Montería.La Luciérnaga, un espacio de humor y opinión de Caracol Radio que acompaña desde hace más de 30 años a sus oyentes en el regreso a casa.




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Colombiana lucha por la custodia de su hija en Alemania: historia del abuso




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Berny Silberwasser, creador de BBC, revive la cerveza Germania en Colombia

En 10AM Hoy por Hoy de Caracol Radio estuvo Berny Silberwasser, pionero de la cerveza artesanal en Colombia, creador de Bogotá Beer Company (BBC) y de la cerveza artesanal La Pola del Pub, para hablar sobre el regreso de la cerveza Germania en el país.