initial

Did You Know? Sushi Was Not Meant to Be Eaten Initially! Uncover Its Surprising Origins

The Story Of Sushi: From its humble beginnings as a way to save food to becoming a global sensation, sushi has come a long way.




initial

Initial SEI formation in LiBOB-, LiDFOB- and LiBF4-containing PEO electrolytes

J. Mater. Chem. A, 2024, 12,9184-9199
DOI: 10.1039/D3TA07175H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Edvin K. W. Andersson, Liang-Ting Wu, Luca Bertoli, Yi-Chen Weng, Daniel Friesen, Kenza Elbouazzaoui, Sophia Bloch, Ruslan Ovsyannikov, Erika Giangrisostomi, Daniel Brandell, Jonas Mindemark, Jyh-Chiang Jiang, Maria Hahlin
A limiting factor for solid polymer electrolyte (SPE)-based Li-batteries is the functionality of the electrolyte decomposition layer that is formed at the Li metal anode during battery operation.
The content of this RSS Feed (c) The Royal Society of Chemistry




initial

Markets decline in initial trade amid soaring inflation, foreign fund exodus

Muted quarterly earnings and weak trends in global markets were also the spoilsport for the markets, traders said




initial

The Holiness Movement by Gary Gilley -- The Holiness Movement actually traces its roots to John Wesley (June 28, 1703 - March 2, 1791) in the eighteenth-century, who taught sort of a two-tiered salvation - The first tier [John 20:22, Luke 24:45 - initial

Revivalists, in the early 1800s, such as Asa Mahan (president of Oberlin College) and evangelist Charles Finney advanced Wesley's theology. They taught "that sinners had the natural ability to believe, and that evangelistic methods could overcome their 'moral' inability through the persuasive power of the Gospel." "Finney and Mahan applied this same understanding to the Christian's growth toward spiritual maturity. To be sanctified, they insisted, required only the same kind of simple, instantaneous faith one exercised to be converted." In 1836 both men experienced what they called "baptisms of the Holy Ghost" which they believed not only freed them from committing sin but also removed their tendency toward sin. Contributing to the spread of this "Holiness" doctrine were the popular camp meeting revivals of the first half of the 1800s, the ministry of Phoebe Palmer (1807-1874) (who taught that sanctification could be reached instantaneously by an act of faith) and the "Prayer Revival" of 1857-1858 (sometimes called the Third Great Awakening). There was also much unrest in Methodist circles as many felt the denomination had lost its fervor. The Wesleyan Methodist (in 1843) and the Free Methodist (in 1860) left the denomination to form the first Holiness denominations. Until the 1890s the Holiness Movement was largely a Methodist phenomenon, but as the Methodists settled more into mainstream Christianity tensions escalated into a schism which resulted in new, non-Methodist, Holiness denominations. These included the Church of God, Anderson, Indiana (1880), Church of the Nazarene (1908) and Pilgrim Holiness Church (1897). The Holiness adherents saw themselves as the true descendents of the Wesleys and practiced strict moral ethics, abstinence from worldly pleasures and amusements and a strong belief in entire sanctification (also known as the "second blessing" and the baptism of the Holy Spirit). More importantly "Holiness teaching offered 19th-century evangelicals a means of overcoming their sectarian conflicts. Doctrine might divide, but the experience of a pure heart would unite all true believers against the threats posed by religious formalism, atheism, and Roman Catholicism." This Holiness emphasis would continue to be spread throughout the 19th century by individuals and groups as diverse as the Salvation Army, Quakers, D. L. Moody, Hannah Whitall Smith, the Y.M.C.A., the Keswick Movement and Oswald Chambers. A brief explanation concerning some of those might prove helpful. ... Maturity in Christ is expected of every believer; freedom from spiritual battle with the world, the flesh and the devil is attained only in the next life. At the same time, we must be careful that we do not over react to Holiness philosophy and believe that godliness is attained through our own self-determined efforts of obedience. We are certainly called to obedience, but it is not a self-energized, self-motivated or self-obtaining obedience. It is an obedience made possible only because of the power of God in our lives. This is the consistent teaching of the New Testament, but we will direct our attention to Romans 8:12-13. So then, brethren, we are under obligation, not to the flesh, to live according to the flesh-for if you are living according to the flesh, you must die; but if by the Spirit you are putting to death the deeds of the body, you will live. Peterson, once again, summarizes things well, "Holiness of life is not simply attained by moral effort nor even by striving to keep the law of God. It is not even a matter of 'letting go and letting God.' Practical holiness involves 'putting to death' in our lives what God has already sentenced to death on the cross ('mortification') and living out the new life given to us by the indwelling Christ. Human effort is required, but not apart from, nor distinct from the activity of God's Spirit, who subdues the flesh as we mortify it in His power, and as we set our minds upon the things of the Spirit." -- Holiness of life should be the heart-felt desire of every Christian. But that holiness is not found in either short-cuts or self effort. **It is found as we pursue righteousness (2 Timothy 2:22) laying aside the deeds of the flesh (Colossians 3:5-10) through the power of the Holy Spirit (Galatians 5:16) and as we behold the glory of the Lord (2 Corinthians 3:18). The Holiness Movement was in many ways a reaction to the dead orthodoxy and lifeless spirituality that infiltrated so much of Christianity during the nineteenth-century. However, its [explicit] remedy, a second blessing [based more on human ability] resulting in the eradication of sinful tendencies and a higher life not available to the unbaptized, went beyond the teaching of Scripture. As is often the case in reactionary movements, the cure [i.e. a cultural salvation, human based rules salvation] may be as bad as the [original sin] disease.




initial

AIT Domains Reseller Program Shows Positive Initial Results




initial

Initial Preparation of a Body for Burial

Dn. Mark enumerates the things you'll need to have ready to prepare a body for burial and explains what to expect when you encounter a dead body.




initial

Will It Work? An Initial Examination of the Processes and Outcomes of Converting Course Materials to CD-ROMs




initial

Modern Transdisciplinarity: Results of the Development of the Prime Cause and Initial Ideas

Aim/Purpose This paper focuses on systematizing and rethinking the conformity of modern transdisciplinarity with its prime cause and initial ideas. Background The difficulties of implementing transdisciplinarity into science and education are connected with the fact that its generally accepted definition, identification characteristics, and methodological features are still missing. In order to eliminate these disadvantages of transdisciplinarity, its prime cause and initial ideas had to be detected. It is also important to analyze the correspondence of the existing opinions about transdisciplinarity with the content of these cause and ideas. Methodology The qualitative analysis of the literature reviews on the subject of transdisciplinary was used in order to determine the correspondence of the opinions about the transdisciplinarity with the meaning of its prime cause and initial ideas. These opinions had to be generalized as well. Through this method, it was possible to detect and classify opinions into 11 groups including 39 stereotypes of transdisciplinarity. For substantiation of transdisciplinary approaches that are consistent with the approaches of contemporary science, C.F. Gauss random variables normal distribution was used. The “Gauss curve” helped to show the place of transdisciplinary and systems transdisciplinary approaches in the structure of academic and systems approaches. The “Gauss curve” also demonstrated the step-by-step “broadening of the scientific worldview horizon due to sequential intensification of synthesis, integration, unification, and generalization of the disciplinary knowledge.” Contribution After reconsideration of the results on qualitative analysis of the literature reviews, the generalized definition of transdisciplinarity could be formulated, including the definition for transdisciplinary and systems transdisciplinary approaches. It was proven that transdisciplinarity is a natural stage for the development of contemporary science and education, and the transdisciplinary approaches were able to suggest the methods and tools to solve the complex and poorly structured problems of science and the society. Findings Many existing stereotypes of transdisciplinarity do not meet its prime cause and initial ideas. Such stereotypes do not have deep philosophic and theoretical substantiation. They also do not suggest the transdisciplinary methods and tools. Thus, the authors of such stereotypes often claim them to be transdisciplinary or suggest perceiving them as transdisciplinarity. This circumstance is the reason why many disciplinary scientists, practitioners, and initiators of higher education view transdisciplinarity as a marginal direction of contemporary science. Based on the generalized definition of transdisciplinarity, as well as its prime cause and initial ideas, it was shown that transdisciplinarity is presented in contemporary science in the form of two different approaches, i.e., the transdisciplinary approach and systems transdisciplinary approach. The objective of the transdisciplinary approach is to ensure science development at the stage of synthesis and integration of disciplinary knowledge, while the objective of the systems transdisciplinary approach is to ensure that the problems of modern society are solved through unification and generalization of the disciplinary knowledge. Recommendation for Researchers The researchers should consider that within the limits of the transdisciplinary approach, the disciplinary specialists are managed. Within the limits of the systems transdisciplinary approach, the disciplinary knowledge is managed. Thus, the transdisciplinary approach is efficient for organization and research with participation of the scientists of the complementary disciplines. An example of such research can be a team of researchers of medical disciplines and complementary disciplines from chemistry, physics, and engineering. The systems transdisciplinary approach is efficient for organization and performance of research with participation of the scientists of non-complementary disciplines such as economics, physics, meteorology, chemistry, ecology, geology, and sociology. Future Research In terms of the main initial idea, transdisciplinarity is formed as a global approach. The global approach should have a traditional institutional form: it should be a science discipline (meta-discipline) and have carriers with the transdisciplinary worldview. Training for such carriers can be organized by the universities within the limits of the systems transdisciplinarity departments and Centers of Systems Transdisciplinary Retraining for Disciplinary Specialists. Thus, it is reasonable to initiate discussion for the idea to reform the disciplinary structure of the universities considering creation of such departments and centers.




initial

A Multicluster Approach to Selecting Initial Sets for Clustering of Categorical Data

Aim/Purpose: This article proposes a methodology for selecting the initial sets for clustering categorical data. The main idea is to combine all the different values of every single criterion or attribute, to form the first proposal of the so-called multiclusters, obtaining in this way the maximum number of clusters for the whole dataset. The multiclusters thus obtained, are themselves clustered in a second step, according to the desired final number of clusters. Background: Popular cluster methods for categorical data, such as the well-known K-Modes, usually select the initial sets by means of some random process. This fact introduces some randomness in the final results of the algorithms. We explore a different application of the clustering methodology for categorical data that overcomes the instability problems and ultimately provides a greater clustering efficiency. Methodology: For assessing the performance of the proposed algorithm and its comparison with K-Modes, we apply both of them to categorical databases where the response variable is known but not used in the analysis. In our examples, that response variable can be identified to the real clusters or classes to which the observations belong. With every data set, we perform a two-step analysis. In the first step we perform the clustering analysis on data where the response variable (the real clusters) has been omitted, and in the second step we use that omitted information to check the efficiency of the clustering algorithm (by comparing the real clusters to those given by the algorithm). Contribution: Simplicity, efficiency and stability are the main advantages of the multicluster method. Findings: The experimental results attained with real databases show that the multicluster algorithm has greater precision and a better grouping effect than the classical K-modes algorithm. Recommendations for Practitioners: The method can be useful for those researchers working with small and medium size datasets, allowing them to detect the underlying structure of the data in an intuitive and reasonable way. Recommendation for Researchers: The proposed algorithm is slower than K-Modes, since it devotes a lot of time to the calculation of the initial combinations of attributes. The reduction of the computing time is therefore an important research topic. Future Research: We are concerned with the scalability of the algorithm to large and complex data sets, as well as the application to mixed data sets with both quantitative and qualitative attributes.




initial

Hybrid encryption of Fernet and initialisation vector with attribute-based encryption: a secure and flexible approach for data protection

With the continuous growth and importance of data, the need for strong data protection becomes crucial. Encryption plays a vital role in preserving the confidentiality of data, and attribute-based encryption (ABE) offers a meticulous access control system based on attributes. This study investigates the integration of Fernet encryption with initialisation vector (IV) and ABE, resulting in a hybrid encryption approach that enhances both security and flexibility. By combining the advantages of Fernet encryption and IV-based encryption, the hybrid encryption scheme establishes an effective and robust mechanism for safeguarding data. Fernet encryption, renowned for its simplicity and efficiency, provides authenticated encryption, guaranteeing both the confidentiality and integrity of the data. The incorporation of an initialisation vector (IV) introduces an element of randomness into the encryption process, thereby strengthening the overall security measures. This research paper discusses the advantages and drawbacks of the hybrid encryption of Fernet and IV with ABE.




initial

Initial Development of a Learners’ Ratified Acceptance of Multibiometrics Intentions Model (RAMIM)




initial

Informing as a Discipline: An Initial Proposal




initial

Better Together? Signaling Interactions in New Venture Pursuit of Initial External Capital

After new ventures have exhausted the limited financial resources of founders, family, and friends, they often pursue initial external capital. To secure investment, entrepreneurs can signal about their venture's latent potential by aligning themselves with reliable third parties. Such affiliations affirm the new venture's legitimacy and provide substantive benefits in the form of mentoring, access to resources, and ongoing monitoring. However, early stage financing is an especially "noisy" signaling environment owing to the large number of startups seeking funding, many of which will not survive. The real value of third party affiliations in this context resides in their ability to unlock the potential of other more pedestrian signals, such as the entrepreneur's characteristics and actions that might otherwise go unnoticed. We borrow from the sensemaking literature to explain how third party affiliation signals disambiguate signals with multiple possible interpretations so that potential investors interpret them positively. Findings support our theory that a startup's characteristics and actions are signals that remain relatively unnoticed unless a startup combines them with a third party affiliation that enhances the signal's value, thus increasing the likelihood of receiving external capital.




initial

Magnification and Correction of the Acolyte Effect: Initial Benefits and Ex Post Settling up in NFL Coaching Careers

What are the long-term consequences of initially beneficial high-reputation workplace ties? Under uncertainty, acolytes (i.e., subordinates with work connections to high-reputation industry leaders) are likely to benefit in terms of signaling fitness for promotion in the external job market. Analysis of promotion outcomes of coaches in the NFL over 31 years showed that the acolyte effect was reduced for individuals for whom uncertainty was the least (acolytes with considerable industry experience or high centrality in the co-worker industry network). There was no support for either a knowledge-transfer or an intrinsic quality explanation for why acolytes initially gained advantage. Rather, the evidence supported the idea that ties to high-reputation leaders were somewhat randomly distributed so that acolytes faced ex post settling up consequences after their promotions: fewer further promotions or lateral moves, more demotions. Thus, acolytes initially benefited from a loose-linkage between their unobservable quality and signals offered by their industry-leader ties, but they also suffered as the unreliability of social network signals became evident. The results suggest that a competitive job market may exhibit self-correction over time. We offer countervailing theory and evidence to the prevailing view that high-reputation third-party endorsements perpetuate a rich-get-richer social structure resistant to performance outcomes.




initial

Initial Informatics Workshop: plans and actions for the future

The first Informatics Workshop of the EU-FP7 funded project EU BON was held on 29-31 May 2013 in Trondheim, Norway. The meeting was hosted by the EU BON partner Norwegian Biodiversity Information Centre (NBIC). The aims were to highlight the link to infrastructures and processes like GEOSS or DataONE and to discuss the data standards and informatics architecture that will be followed by the EU BON project.

During the three-days of the workshop, the participants of the meeting discussed the important aspects regarding the informatics architecture and decided on the next steps to develop a new open-access platform for sharing biodiversity data and tools in order to advance the European biodiversity knowledge.  On the first day, the aim was to highlight the link of EU BON with GEOSS, GEO BON and other processes like DataONE to find synergies and to build on work that was conducted in these processes. On the second day, detailed discussion on the specific tasks of the workgroup took place. The afternoon session was split into 3 different tracks where issues like architectural design, review and guidelines for using data standards, the design of monitoring sites and the gap analysis of existing biodiversity data were analyzed and discussed.

It was agreed that a new platform is needed which should be built on existing solutions. Thus, the platform will use the technical solutions of the DataONE network that will be adjusted to the specific needs of the EU BON project. EU BON Partners will implement DataONE Member Nodes to start the process and a DataOne coordinating node may be established towards 2015. Furthermore, it was also decided to join and support the GEO BON Working Group pilot project on automating the data flows for the Essential Biodiversity Variables.





initial

Initial population trends from a 5-year butterfly monitoring scheme





initial

Workers’ comp study finds use of ERs for initial treatment varies state to state

Cambridge, MA — The percentages of injured workers who visited an ER – instead of physician offices or urgent care clinics, which are less costly alternatives – for their initial medical treatment varied across 28 states, according to a recent study from the Workers Compensation Research Institute.




initial

OSHA grants initial approval of Massachusetts State Plan for public-sector workers

Washington — A State Plan covering Massachusetts’ state and local government employees is now a reality after OSHA announced its initial approval.




initial

Feasibility, acceptability, and initial outcomes of a psychological adjustment and reintegration program for transitioned military veterans

Reintegration and adjustment to civilian life after military service is crucial for veterans’ mental and physical health. However, there is a lack of evidence-based interventions in Australia that specifically… Read the full article ›

The post Feasibility, acceptability, and initial outcomes of a psychological adjustment and reintegration program for transitioned military veterans was curated by information for practice.



  • Open Access Journal Articles

initial

Research Campaign to Advance Understanding of Gulf of Mexico Loop Current Moves Forward By Awarding $10.3 Million in Initial Grants

Following recommendations from a National Academies of Sciences, Engineering, and Medicine report released earlier this year, the National Academies’ Gulf Research Program (GRP) is developing a long-term research campaign to improve understanding and prediction of the Gulf of Mexico Loop Current System (LCS).




initial

Heritable Genome Editing Not Yet Ready to Be Tried Safely and Effectively in Humans - Initial Clinical Uses, If Permitted, Should Be Limited to Serious Single-Gene Diseases

Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably without introducing undesired changes — a criterion that has not yet been met by any genome editing technology, says a new report by an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.’s Royal Society.




initial

Initial prescriptions of sedatives among older stroke survivors may include too many pills

Research Highlights: Within 90 days after having an ischemic (clot-caused) stroke, about 5% of stroke survivors ages 65 and older were prescribed benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures)...





initial

aarch64-linux-gnu-gcc-initial 9.3.0-1parabola1 armv7h

The GNU Compiler Collection - cross compiler for aarch64 target




initial

Futurama Initially Wasn't Allowed To Recruit Animators From These Rival Shows

Fox was unusually strict about Futurama not being allowed to hire animators from certain other series to work on its first season.




initial

[ B.19 (10/96) ] - Abbreviations and initials used in telecommunications

Abbreviations and initials used in telecommunications




initial

[ B.19 (11/88) ] - Abbreviations and initials used in telecommunications

Abbreviations and initials used in telecommunications




initial

[ P.917 (01/19) ] - Subjective test methodology for assessing impact of initial loading delay on quality of experience

Subjective test methodology for assessing impact of initial loading delay on quality of experience




initial

The Rocky Horror Picture Show still draws crowds of superfans and virgins alike nearly five decades after its initial release

The Rocky Horror Picture Show is unlike anything else…



  • Arts & Culture

initial

Engaging, Explicit, and Elaborated: An Initial Trial of Media-Enhanced Preschool Vocabulary Instruction

Children from backgrounds of poverty often lag behind more advantaged peers in early language skills, including breadth and depth of vocabulary knowledge. We report the results of a pilot study of an explicit and elaborated vocabulary intervention in preschool classrooms serving children from lower-income backgrounds. The intervention used multimodal instruction, including segments from public television children's programs and interactive games, to build children's knowledge of and semantic connections for 128 words across 18 weeks of daily lessons.




initial

Intraarterial Administration of Peptide Receptor Radionuclide Therapy in Patients with Advanced Meningioma: Initial Safety and Efficacy

Visual Abstract




initial

Problem Notes for SAS®9 - 66542: The initial loading of a rule set and a rule flow takes significantly longer in SAS Business Rules Manager 3.3 compared with release 3.2

In SAS Business Rules Manager 3.3, the initial loading of a rule set and a rule flow takes significantly longer than it does in release 3.2. When this problem happens, long time gaps are evident in the local




initial

TRIM46 Is Required for Microtubule Fasciculation In Vivo But Not Axon Specification or Axon Initial Segment Formation

Vertebrate nervous systems use the axon initial segment (AIS) to initiate action potentials and maintain neuronal polarity. The microtubule-associated protein tripartite motif containing 46 (TRIM46) was reported to regulate axon specification, AIS assembly, and neuronal polarity through the bundling, or fasciculation, of microtubules in the proximal axon. However, these claims are based on TRIM46 knockdown in cultured neurons. To investigate TRIM46 function in vivo, we examined male and female TRIM46 knock-out mice. Contrary to previous reports, we find that TRIM46 is dispensable for axon specification and AIS formation. TRIM46 knock-out mice are viable, have normal behavior, and have normal brain structure. Thus, TRIM46 is not required for AIS formation, axon specification, or nervous system function. However, we confirm that TRIM46 is required for microtubule fasciculation. We also show TRIM46 enrichment in the first ~100 μm of axon occurs independently of ankyrinG (AnkG) in vivo, although AnkG is required to restrict TRIM46 only to the AIS. Our results highlight the need for further investigation of the mechanisms by which the AIS and microtubules interact to shape neuronal structure and function.




initial

Initial Listing of the Gulf Coast UCO (Argus) (60,000 lb) Futures and the Gulf Coast UCO (Argus) Futures Contracts




initial

Initial Listing of the Chicago No1 Busheling Ferrous Scrap (Fastmarkets) Futures Contract




initial

Initial Listing of Four (4) Crude Oil (Argus) BALMO Futures Contracts




initial

New Product Summary: Initial Listing of the Chicago No1 Busheling Ferrous Scrap (Fastmarkets) Futures Contract - Effective December 16, 2024




initial

New Product Summary: Initial Listing of Four (4) Crude Oil (Argus) BALMO Futures Contracts - Effective December 16, 2024




initial

New Product Summary: Initial Listing of the Gulf Coast UCO (Argus) (60,000 lb) Futures and the Gulf Coast UCO (Argus) Futures Contracts - Effective December 16, 2024




initial

Delaware Confirms Initial Cases of West Nile Virus in a Human, Horses for 2024

The Delaware Public Health Laboratory has identified this year's first human case of West Nile Virus (WNV) in a New Castle County resident. Additionally, the Office of the State Veterinarian within the Delaware Department of Agriculture has confirmed the first two cases of WNV in Delaware horses this year.



  • Department of Agriculture
  • Division of Public Health
  • News
  • Eastern equine encephalitis
  • first human in delaware
  • horses
  • Office of the State Veterinarian
  • West Nile Virus

initial

Tempus ECO initial setup summary not matching timing report results

We are currently setting up the Tempus flow and have ran into some mismatched data regarding ECO and timing reports. I generated a timing report before running ECO and saw six total setup violations. When running opt_signoff -setup, the initial setup summary that was printed in the shell only showed one violation. I can see that violation from the initial setup summary in my pre-ECO timing report and it is not the worst path. Upon further investigation, I forced the tool to try to fix setup on one of the other five violations from the timing report using the opt_signoff_select_setup_endpoints attribute and the tool said that the endpoint had positive slack and would be ignored.

Has anyone experienced something like this before?




initial

Initial Savings May Hide True Cost of Prostate Cancer Care

Title: Initial Savings May Hide True Cost of Prostate Cancer Care
Category: Health News
Created: 8/23/2010 12:10:00 PM
Last Editorial Review: 8/24/2010 12:00:00 AM




initial

Initial Experience with [177Lu]Lu-PSMA-617 After Regulatory Approval for Metastatic Castration-Resistant Prostate Cancer: Efficacy, Safety, and Outcome Prediction

[177Lu]Lu-PSMA-617 was approved by the U.S. Food and Drug Administration for patients with prostate-specific membrane antigen (PSMA)–positive metastatic castration-resistant prostate cancer (mCRPC). Since the time of regulatory approval, however, real-world data have been lacking. This study investigated the efficacy, safety, and outcome predictors of [177Lu]Lu-PSMA-617 at a major U.S. academic center. Methods: Patients with mCRPC who received [177Lu]Lu-PSMA-617 at the Johns Hopkins Hospital outside clinical trials were screened for inclusion. Patients who underwent [177Lu]Lu-PSMA-617 and had available outcome data were included in this study. Outcome data included prostate-specific antigen (PSA) response (≥50% decline), PSA progression-free survival (PFS), and overall survival (OS). Toxicity data were evaluated according to the Common Terminology Criteria for Adverse Events version 5.03. The study tested the association of baseline circulating tumor DNA mutational status in homologous recombination repair, PI3K alteration pathway, and aggressive-variant prostate cancer–associated genes with treatment outcome. Baseline PSMA PET/CT images were analyzed using SelectPSMA, an artificial intelligence algorithm, to predict treatment outcome. Associations with the observed treatment outcome were evaluated. Results: All 76 patients with PSMA-positive mCRPC who received [177Lu]Lu-PSMA-617 met the inclusion criteria. A PSA response was achieved in 30 of 74 (41%) patients. The median PSA PFS was 4.1 mo (95% CI, 2.0–6.2 mo), and the median OS was 13.7 mo (95% CI, 11.3–16.1 mo). Anemia of grade 3 or greater, thrombocytopenia, and neutropenia were observed in 9 (12%), 3 (4%), and 1 (1%), respectively, of 76 patients. Transient xerostomia was observed in 23 (28%) patients. The presence of aggressive-variant prostate cancer–associated genes was associated with a shorter PSA PFS (median, 1.3 vs. 6.3 mo; P = 0.040). No other associations were observed between circulating tumor DNA mutational status and treatment outcomes. Eighteen of 71 (25%) patients classified by SelectPSMA as nonresponders had significantly lower rates of PSA response than patients classified as likely responders (6% vs. 51%; P < 0.001), a shorter PSA PFS (median, 1.3 vs. 6.3 mo; P < 0.001), and a shorter OS (median, 6.3 vs. 14.5 mo; P = 0.046). Conclusion: [177Lu]Lu-PSMA-617 offered in a real-world setting after regulatory approval in the United States demonstrated antitumor activity and a favorable toxicity profile. Artificial-intelligence–based analysis of baseline PSMA PET/CT images may improve patient selection. Validation of these findings on larger cohorts is warranted.




initial

GSTN Issues Advisory regarding IMS during initial phase of its implementation

Invoice Management System (IMS) is an optional facility introduced from October 2024 on GST Portal, on which the invoices/records saved/furnished by the supplier in GSTR-1/1A/IFF...




initial

TikTok ventures into mobile gaming, initially in partnership with Zynga

TikTok is experimenting with games, initially in partnership with mobile gaming giant Zynga. On Monday, Zynga announced its plans to launch a new HTML5-based game, “Disco Loco 3D,” exclusively on the TikTok platform. The casual game is a single-player endless runner where players collect their own dance moves while challenging friends, avoiding obstacles and collecting […]

© 2024 TechCrunch. All rights reserved. For personal use only.




initial

Inherit, initial, unset, revert

Today we’re going to take a quick look at a few special CSS keywords you can use on any CSS property: inherit, initial, revert, and unset. Also, we will ask where and when to use them to the greatest effect, and if we need more of those keywords.

The first three were defined in the Cascading Level 3 spec, while revert was added in Cascading Level 4. Despite 4 still being in draft revert is already supported. See also the MDN revert page, Chris Coyier’s page, and my test page

inherit

The inherit keyword explicitly tells an element that it inherits the value for this declaration from its parent. Let’s take this example:

.my-div {
	margin: inherit;
}

.my-div a {
	color: inherit;
}

The second declaration is easiest to explain, and sometimes actually useful. It says that the link colour in the div should be the same as the text colour. The div has a text colour. It’s not specified here, but because color is inherited by default the div gets the text color of its parent. Let’s say it’s black.

Links usually have a different colour. As a CSS programmer you frequently set it, and even if you don’t browsers automatically make it blue for you. Here, however, we explicitly tell the browsers that the link colour should be inherited from its parent, the div. In our example links become black.

(Is this a good idea? Occasionally. But if you remove the colour difference between links and main text, make sure your links are underlined. Your users will thank you.)

Now let’s look at the margin: inherit. Normally margins don’t inherit, and for good reason. The fact that an element has margin-left: 10% does not mean all of its descendents should also get that margin. In fact, you most likely don’t want that. Margins are set on a per-case basis.

This declaration tells the div to use the margin specified on its parent, however. This is an odd thing to specify, and I never saw a practical use case in the wild. Still CSS, being ridiculously powerful, allows it.

In any case, that’s how the inherit keyword works. Using it for font sizes or colours may occasionally be a good idea. In other contexts - rarely.

And keep the difference between inheriting and non-inheriting properties in mind. It’s going to be important later on.

initial

The initial keywords sets the property back to its initial value. This is the value specified in the W3C specification for that property.

Initial values from the spec are a bit of a mixed bag. Some make sense, others don’t, really. float: none and background-color: transparent are examples of the first category. Of course an element does not have a background colour without you specifying one, nor does it float automatically.

Others are historically determined, such as background-repeat: repeat. Back in the Stone Age before CSS all background images repeated, and the CSS1 specification naturally copied this behaviour.

Still others are essentially arbitrary, such as display: inline. Why did W3C opt for inline instead of block? I don’t know, and it doesn’t really matter any more. They had to decide on an initial value, and while inline is somewhat strange, block would be equally strange.

In any case, the initial keyword makes the property revert to this initial value from the specification, whether that makes sense or not.

unset

When we get to the unset value the distinction between inheriting and non-inheriting properties becomes important. unset has a different effect on them.

  • If a property is normally inherited, unset means inherit.
  • If a property is normally not inherited, unset means initial.

revert

revert, the newest of these keywords, also distinguishes between inheriting and non-inheriting properties.

  • If a property is normally inherited, revert means inherit.
  • If a property is normally not inherited, revert reverts to the value specified in the browser style sheet.

all

Finally, we should treat all. It is not a value but a property, or rather, the collection of all CSS properties on an element. It only takes one of the keywords we discussed, and allows you to apply that keyword to all CSS properties. For instance:

.my-div {
	all: initial;
}

Now all CSS properties on the div are set to initial.

Examples

The reaction of my test page to setting the display of all elements to the four keywords is instructive. My test script sets the following style:

body * {
	display: [inherit | initial | unset | revert] !important;
}

The elements react as follows:

  • display: inherit: all elements now inherit their display value from the body. Since the body has display: block all elements get that value, whether that makes sense or not.
  • display: initial: the initial value of display is inline. Therefore all elements get that value, whether that makes sense or not.
  • display: unset: display does not inherit. Therefore this behaves as initial and all elements get display: inline.
  • display: revert: display does not inherit. Therefore the defaults of the browser style sheet are restored, and each element gets its proper display — except for the dl, which I had given a display: grid. This value is now supplanted by the browser-provided block.

Unfortunately the same test page also contains a riddle I don’t understand the behaviour of <button>s when I set color to the four keywords:

  • color: inherit: all elements, including <button>s, now inherit their colour from the body, which is blue. So all text becomes blue.
  • color: initial: since the initial value of color is black, all elements, including <button>s, become black.
  • color: unset: color inherits. Therefore this behaves as inherit and all elements, including <button>s, become blue.
  • color: revert: This is the weird one. All elements become blue, except for <button>s, which become black. I don’t understand why. Since colors inherit, I expected revert to work as inherit and the buttons to also become blue. But apparently the browser style sheet of button {color: black} (more complicated in practice) is given precedence. Yes, revert should remove author styles (the ones we write), and that would cause the black from the browser style sheet to be applied, but only if a property does not inherit — and color does. I don’t know why the browser style sheet is given precedence in this case. So I’m going to cop out and say form elements are weird.

Practical use: almost none

The purpose of both unset and revert is to wipe the slate clean and return to the initial and the browser styles, respectively — except when the property inherits; in that case, inheritance is still respected. initial, meanwhile, wipes the slate even cleaner by also reverting inheriting properties to their initial values.

This would be useful when you create components that should not be influenced by styles defined elsewhere on the page. Wipe the slate clean, start styling from zero. That would help modularisation.

But that’s not how these keywords work. We don’t want to revert to the initial styles (which are sometimes plain weird) but to the browser style sheet. unset comes closest, but it doesn’t touch inherited styles, so it only does half of what we want.

So right now these keywords are useless — except for inherit in a few specific situations usually having to do with font sizes and colours.

New keyword: default

Chris Coyier argues we need a new value which he calls default. It reverts to the browser style sheet in all cases, even for inherited properties. Thus it is a stronger version of revert. I agree. This keyword would be actually useful. For instance:

.my-component,.my-component * {
	all: default;
	font-size: inherit;
	font-family: inherit;
	color: inherit;
}

Now we have a component that’s wiped clean, except that we decide to keep the fonts and colour of the main page. The rest is a blank slate that we can style as we like. That would be a massive boon to modularisation.

New keyword: cascade

For years now I have had the feeling that we need yet another keyword, which I’ll call cascade for now. It would mean “take the previous value in the cascade and apply it here.” For instance:

.my-component h2 {
	font-size: 24px;
}

.my-other-component h2 {
	font-size: 3em;
}

h2#specialCase {
	font-size: clamp(1vw,cascade,3vw)
}

In this (slightly contrived) example I want to clamp the font-size of a special h2 between 1vw and 3vw, with the preferred value being the one defined for the component I’m working in. Here, cascade would mean: take the value the cascade would deliver if this rule didn’t exist. This would make the clamped font size use either 24px or 3em as its preferred value, depending on which component we’re in.

The problem with this example is that it could also use custom properties. Just set --h2size to either 24px or 3em, use it in the clamp, and you’re done.

.my-component h2 {
	--h2size: 24px;
	font-size: var(--h2size);
}

.my-other-component h2 {
	--h2size: 3em;
	font-size: var(--h2size);
}

h2#specialCase {
	font-size: clamp(1vw,var(--h2size),3vw)
}

Still, this is but the latest example I created. I have had this thought many, many times, but because I didn’t keep track of my use cases I’m not sure if all of them could be served by custom properties.

Also, suppose you inherit a very messy CSS code base with dozens of components written at various skill levels. In that case adding custom properties to all components might be impractical, and the cascade keyword might help.

Anyway, I barely managed to convince myself, so professional standard writers will certainly not be impressed. Still, I thought I’d throw it out here to see if anyone else has a use case for cascade that cannot be solved with custom properties.



  • CSS for JavaScripters

initial

Initial hiccups delay e-Health registration at Kozhikode MCH

Patients and caregivers endure long wait times for outpatient tickets as glitches in the new system hinder the registration process




initial

Naivete and Sophistication in Initial and Repeated Play in Games [electronic journal].




initial

Lift the Ban? Initial Employment Restrictions and Refugee Labour Market Outcomes [electronic journal].




initial

Markets give up initial gains dragged by sharp fall in Kotak Bank, unabated foreign fund outflows

Equity markets open strong but later decline; HDFC Bank gains, Kotak Mahindra Bank falls, global markets mixed