experiments

Experiments illuminate key component of plants' immune systems




experiments

Games, experiments and Bible stories

OM uses an educational programme called KidsGames to share Bible stories in a public school.




experiments

May 26 2009 Long Lost Radio History Image - Radio Rhema Experiments

Over the Christmas - New Year period of 1976-77, Radio Rhema broadcast an experimental 10 day short-term AM program from Ferrymead Historic Park, Christchurch, New Zealand...




experiments

10 Ingenious Tech Experiments That Think Outside the Box

Innovation in technology often means thinking outside the box. This list highlights some of the most ingenious tech experiments that push boundaries and showcase human creativity. These projects aren’t just theoretical; they have real-world applications, making a big impact across various industries. From energy efficiency to data storage, these innovations show how inventive thinking can […]

The post 10 Ingenious Tech Experiments That Think Outside the Box appeared first on Listverse.




experiments

Architect Benny Kuriakose experiments with light and design to help autistic kids in Chennai

Autism Awareness Month: At the Sankalp headquarters in Kolappancheri, architect Benny Kuriakose has experimented with natural lighting, curved pathways and verandahs as buffer zones




experiments

A new bakery in Visakhapatnam experiments with preservative-free artisanal breads

Breadway in Visakhapatnam focuses on offering authentic flavours through artisanal breads and bakes




experiments

Early Results of Experiments with Responsive Open Learning Environments

Responsive open learning environments (ROLEs) are the next generation of personal learning environments (PLEs). While PLEs rely on the simple aggregation of existing content and services mainly using Web 2.0 technologies, ROLEs are transforming lifelong learning by introducing a new infrastructure on a global scale while dealing with existing learning management systems, institutions, and technologies. The requirements engineering process in highly populated test-beds is as important as the technology development. In this paper, we will describe first experiences deploying ROLEs at two higher learning institutions in very different cultural settings. The Shanghai Jiao Tong University in China and at the “Center for Learning and Knowledge Management and Department of Information Management in Mechanical Engineering” (ZLW/IMA) at RWTH Aachen University have exposed ROLEs to theirs students in already established courses. The results demonstrated to readiness of the technology for large-scale trials and the benefits for the students leading to new insights in the design of ROLEs also for more informal learning situations.




experiments

Sheer Curation of Experiments: Data, Process, Provenance

This paper describes an environment for the “sheer curation” of the experimental data of a group of researchers in the fields of biophysics and structural biology. The approach involves embedding data capture and interpretation within researchers' working practices, so that it is automatic and invisible to the researcher. The environment does not capture just the individual datasets generated by an experiment, but the entire workflow that represent the “story” of the experiment, including intermediate files and provenance metadata, so as to support the verification and reproduction of published results. As the curation environment is decoupled from the researchers’ processing environment, the provenance is inferred from a variety of domain-specific contextual information, using software that implements the knowledge and expertise of the researchers. We also present an approach to publishing the data files and their provenance according to linked data principles by using OAI-ORE (Open Archives Initiative Object Reuse and Exchange) and OPMV.





experiments

Preparing research samples for safe arrival at centers and facilities: recipes for successful experiments

Preparation of biomacromolecules for structural biology studies is a complex and time-consuming process. The goal is to produce a highly concentrated, highly pure product that is often shipped to large facilities with tools to prepare the samples for crystallization trials or for measurements at synchrotrons and cryoEM centers. The aim of this article is to provide guidance and to discuss general considerations for shipping biomacromolecular samples. Details are also provided about shipping samples for specific experiment types, including solution- and cryogenic-based techniques. These guidelines are provided with the hope that the time and energy invested in sample preparation is not lost due to shipping logistics.




experiments

A method with ultra-high angular resolution for X-ray diffraction experiments

In X-ray diffraction measurements, the angular resolution has a detection limit due to the receiving size of the detector. In many cases this detection limit is too large and must be breached to obtain the desired information. A novel method is proposed here by making the detector simultaneously measuring and moving. Using the deconvolution algorithm to remove the convolution effect, the pixel size limitation is finally broken. The algorithm used is not a common one, and suppresses signals at high frequencies, ensuring the reliability of the peak shape after restoration. The feasibility of this method is verified by successfully measuring the crystal truncation rod signal of SrTiO3 single crystal, and the resolution is nearly ten times higher than that of a single pixel. Moreover, this method greatly reduces the noise and improves the signal-to-noise ratio.




experiments

xrdPlanner: exploring area detector geometries for powder diffraction and total scattering experiments

xrdPlanner is a software package designed to aid in the planning and preparation of powder X-ray diffraction and total scattering beam times at synchrotron facilities. Many modern beamlines provide a flexible experimental setup and may have several different detectors available. In combination with a range of available X-ray energies, it often makes it difficult for the user to explore the available parameter space relevant for a given experiment prior to the scheduled beam time. xrdPlanner was developed to provide a fast and straightforward tool that allows users to visualize the accessible part of reciprocal space of their experiment at a given combination of photon energy and detector geometry. To plan and communicate the necessary geometry not only saves time but also helps the beamline staff to prepare and accommodate for an experiment. The program is tailored toward powder X-ray diffraction and total scattering experiments but may also be useful for other experiments that rely on an area detector and for which detector placement and achievable momentum-transfer range are important experimental parameters.




experiments

Efficient end-to-end simulation of time-dependent coherent X-ray scattering experiments

Physical optics simulations for beamlines and experiments allow users to test experiment feasibility and optimize beamline settings ahead of beam time in order to optimize valuable beam time at synchrotron light sources like NSLS-II. Further, such simulations also help to develop and test experimental data processing methods and software in advance. The Synchrotron Radiation Workshop (SRW) software package supports such complex simulations. We demonstrate how recent developments in SRW significantly improve the efficiency of physical optics simulations, such as end-to-end simulations of time-dependent X-ray photon correlation spectroscopy experiments with partially coherent undulator radiation (UR). The molecular dynamics simulation code LAMMPS was chosen to model the sample: a solution of silica nanoparticles in water at room temperature. Real-space distributions of nanoparticles produced by LAMMPS were imported into SRW and used to simulate scattering patterns of partially coherent hard X-ray UR from such a sample at the detector. The partially coherent UR illuminating the sample can be represented by a set of orthogonal coherent modes obtained by simulation of emission and propagation of this radiation through the coherent hard X-ray (CHX) scattering beamline followed by a coherent-mode decomposition. GPU acceleration is added for several key functions of SRW used in propagation from sample to detector, further improving the speed of the calculations. The accuracy of this simulation is benchmarked by comparison with experimental data.




experiments

A distributed data processing scheme based on Hadoop for synchrotron radiation experiments

With the development of synchrotron radiation sources and high-frame-rate detectors, the amount of experimental data collected at synchrotron radiation beamlines has increased exponentially. As a result, data processing for synchrotron radiation experiments has entered the era of big data. It is becoming increasingly important for beamlines to have the capability to process large-scale data in parallel to keep up with the rapid growth of data. Currently, there is no set of data processing solutions based on the big data technology framework for beamlines. Apache Hadoop is a widely used distributed system architecture for solving the problem of massive data storage and computation. This paper presents a set of distributed data processing schemes for beamlines with experimental data using Hadoop. The Hadoop Distributed File System is utilized as the distributed file storage system, and Hadoop YARN serves as the resource scheduler for the distributed computing cluster. A distributed data processing pipeline that can carry out massively parallel computation is designed and developed using Hadoop Spark. The entire data processing platform adopts a distributed microservice architecture, which makes the system easy to expand, reduces module coupling and improves reliability.




experiments

First X-ray spectral ptychography and resonant ptychographic computed tomography experiments at the SWING beamline from Synchrotron SOLEIL

X-ray ptychography and ptychographic computed tomography have seen a rapid rise since the advent of fourth-generation synchrotrons with a high degree of coherent radiation. In addition to quantitative multiscale structural analysis, ptychography with spectral capabilities has been developed, allowing for spatial-localized multiscale structural and spectral information of samples. The SWING beamline of Synchrotron SOLEIL has recently developed a nanoprobe setup where the endstation's first spectral and resonant ptychographic measurements have been successfully conducted. A metallic nickel wire sample was measured using 2D spectral ptychography in XANES mode and resonant ptychographic tomography. From the 2D spectral ptychography measurements, the spectra of the components of the sample's complex-valued refractive index, δ and β, were extracted, integrated along the sample thickness. By performing resonance ptychographic tomography at two photon energies, 3D maps of the refractive index decrement, δ, were obtained at the Ni K-edge energy and another energy above the edge. These maps allowed the detection of impurities in the Ni wire. The significance of accounting for the atomic scattering factor is demonstrated in the calculation of electron density near a resonance through the use of the δ values. These results indicate that at the SWING beamline it is possible to conduct state-of-the-art spectral and resonant ptychography experiments using the nanoprobe setup.




experiments

Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments

Structural biology experiments benefit significantly from state-of-the-art synchrotron data collection. One can acquire macromolecular crystallography (MX) diffraction data on large-area photon-counting pixel-array detectors at framing rates exceeding 1000 frames per second, using 200 Gbps network connectivity, or higher when available. In extreme cases this represents a raw data throughput of about 25 GB s−1, which is nearly impossible to deliver at reasonable cost without compression. Our field has used lossless compression for decades to make such data collection manageable. Many MX beamlines are now fitted with DECTRIS Eiger detectors, all of which are delivered with optimized compression algorithms by default, and they perform well with current framing rates and typical diffraction data. However, better lossless compression algorithms have been developed and are now available to the research community. Here one of the latest and most promising lossless compression algorithms is investigated on a variety of diffraction data like those routinely acquired at state-of-the-art MX beamlines.




experiments

Development and performance simulations of a soft X-ray and XUV split-and-delay unit at beamlines FL23/24 at FLASH2 for time-resolved two-color pump–probe experiments

The split-and-delay unit (SDU) at FLASH2 will be upgraded to enable the simultaneous operation of two temporally, spatially and spectrally separated probe beams when the free-electron laser undulators are operated in a two-color scheme. By means of suitable thin filters and an optical grating beam path a wide range of combinations of photon energies in the spectral range from 150 eV to 780 eV can be chosen. In this paper, simulations of the spectral transmission and performance parameters of the filter technique are discussed, along with a monochromator with dispersion compensation presently under construction.




experiments

CHiMP: deep-learning tools trained on protein crystallization micrographs to enable automation of experiments

A group of three deep-learning tools, referred to collectively as CHiMP (Crystal Hits in My Plate), were created for analysis of micrographs of protein crystallization experiments at the Diamond Light Source (DLS) synchrotron, UK. The first tool, a classification network, assigns images into categories relating to experimental outcomes. The other two tools are networks that perform both object detection and instance segmentation, resulting in masks of individual crystals in the first case and masks of crystallization droplets in addition to crystals in the second case, allowing the positions and sizes of these entities to be recorded. The creation of these tools used transfer learning, where weights from a pre-trained deep-learning network were used as a starting point and repurposed by further training on a relatively small set of data. Two of the tools are now integrated at the VMXi macromolecular crystallography beamline at DLS, where they have the potential to absolve the need for any user input, both for monitoring crystallization experiments and for triggering in situ data collections. The third is being integrated into the XChem fragment-based drug-discovery screening platform, also at DLS, to allow the automatic targeting of acoustic compound dispensing into crystallization droplets.




experiments

Automated pipeline processing X-ray diffraction data from dynamic compression experiments on the Extreme Conditions Beamline of PETRA III

Presented and discussed here is the implementation of a software solution that provides prompt X-ray diffraction data analysis during fast dynamic compression experiments conducted within the dynamic diamond anvil cell technique. It includes efficient data collection, streaming of data and metadata to a high-performance cluster (HPC), fast azimuthal data integration on the cluster, and tools for controlling the data processing steps and visualizing the data using the DIOPTAS software package. This data processing pipeline is invaluable for a great number of studies. The potential of the pipeline is illustrated with two examples of data collected on ammonia–water mixtures and multiphase mineral assemblies under high pressure. The pipeline is designed to be generic in nature and could be readily adapted to provide rapid feedback for many other X-ray diffraction techniques, e.g. large-volume press studies, in situ stress/strain studies, phase transformation studies, chemical reactions studied with high-resolution diffraction etc.




experiments

Quality assessment of the wide-angle detection option planned at the high-intensity/extended Q-range SANS diffractometer KWS-2 combining experiments and McStas simulations

For a reliable characterization of materials and systems featuring multiple structural levels, a broad length scale from a few ångström to hundreds of nanometres must be analyzed and an extended Q range must be covered in X-ray and neutron scattering experiments. For certain samples or effects, it is advantageous to perform such characterization with a single instrument. Neutrons offer the unique advantage of contrast variation and matching by D-labeling, which is of great value in the characterization of natural or synthetic polymers. Some time-of-flight small-angle neutron scattering (TOF-SANS) instruments at neutron spallation sources can cover an extended Q range by using a broad wavelength band and a multitude of detectors. The detectors are arranged to cover a wide range of scattering angles with a resolution that allows both large-scale morphology and crystalline structure to be resolved simultaneously. However, for such analyses, the SANS instruments at steady-state sources operating in conventional monochromatic pinhole mode rely on additional wide-angle neutron scattering (WANS) detectors. The resolution must be tuned via a system of choppers and a TOF data acquisition option to reliably measure the atomic to mesoscale structures. The KWS-2 SANS diffractometer at Jülich Centre for Neutron Science allows the exploration of a wide Q range using conventional pinhole and lens focusing modes and an adjustable resolution Δλ/λ between 2 and 20%. This is achieved through the use of a versatile mechanical velocity selector combined with a variable slit opening and rotation frequency chopper. The installation of WANS detectors planned on the instrument required a detailed analysis of the quality of the data measured over a wide angular range with variable resolution. This article presents an assessment of the WANS performance by comparison with a McStas [Willendrup, Farhi & Lefmann (2004). Physica B, 350, E735–E737] simulation of ideal experimental conditions at the instrument.




experiments

Use of a confocal optical device for centring a diamond anvil cell in single-crystal X-ray diffraction experiments

High-pressure crystallographic data can be measured using a diamond anvil cell (DAC), which allows the sample to be viewed only along a cell vector which runs perpendicular to the diamond anvils. Although centring a sample perpendicular to this direction is straightforward, methods for centring along this direction often rely on sample focusing, measurements of the direct beam or short data collections followed by refinement of the crystal offsets. These methods may be inaccurate, difficult to apply or slow. Described here is a method based on precise measurement of the offset in this direction using a confocal optical device, whereby the cell centre is located at the mid-point of two measurements of the distance between a light source and the external faces of the diamond anvils viewed along the forward and reverse directions of the cell vector. It is shown that the method enables a DAC to be centred to within a few micrometres reproducibly and quickly.




experiments

distect: automatic sample-position tracking for X-ray experiments using computer vision algorithms

Soft X-ray spectroscopy is an important technique for measuring the fundamental properties of materials. However, for measurements of samples in the sub-millimetre range, many experimental setups show limitations. Position drifts on the order of hundreds of micrometres during thermal stabilization of the system can last for hours of expensive beam time. To compensate for drifts, sample tracking and feedback systems must be used. However, in complex sample environments where sample access is very limited, many existing solutions cannot be applied. In this work, we apply a robust computer vision algorithm to automatically track and readjust the sample position in the dozens of micrometres range. Our approach is applied in a complex sample environment, where the sample is in an ultra-high vacuum chamber, surrounded by cooled thermal shields to reach sample temperatures down to 2.5 K and in the center of a superconducting split coil. Our implementation allows sample-position tracking and adjustment in the vertical direction since this is the dimension where drifts occur during sample temperature change in our setup. The approach can be easily extended to 2D. The algorithm enables a factor of ten improvement in the overlap of a series of X-ray absorption spectra in a sample with a vertical size down to 70 µm. This solution can be used in a variety of experimental stations, where optical access is available and sample access by other means is reduced.




experiments

Tiny Experiments: How Little Moments Influence Your Life

In a world that often emphasizes grand gestures and monumental achievements, it’s easy to overlook the profound impact of small actions. Yet, it’s these minuscule steps that are the true catalysts for change and progress in our lives. “Tiny Experiments.” I keep these words on a Post-It note on my monitor, a daily reminder that the key to unlocking my potential and propelling myself towards my desired future lies in the willingness to take small, manageable actions. Now, you might be skeptical. What can you really accomplish in just a few minutes? The answer is—a lot more than you think. Examples of Tiny Experiments Here are some of the tiny experiments I’ve integrated into my routine: A Ten-Minute Run: It’s short, yes, but it boosts my energy and clears my mind, making me more productive. One Strategic Email: Something as simple as sending an email can advance my projects, like moving forward with an upcoming TV series. Fifty Pushups: This quick burst of physical activity increases my physical stamina and mental toughness. Ten-Minute Meditation: Helps me center my thoughts and combat the stresses of daily life. A Five-Minute Call: Reconnecting with a friend or family member, like my mom, nurtures...

The post Tiny Experiments: How Little Moments Influence Your Life first appeared on Chase Jarvis.

The post Tiny Experiments: How Little Moments Influence Your Life appeared first on Chase Jarvis.




experiments

Design of Experiments Uncovers Hidden Factors in Production Processes

Design of Experiments (DOE) helps improve products and processes more efficiently, providing a comprehensive understanding of influences on the end result.




experiments

Verification experiments related to increase of efficiency of air-conditioning and control technologies at a data centre

Verification experiments related to increase of efficiency of air-conditioning and control technologies at a data centre




experiments

HSTP-VID-WPOM - Working practices using objective metrics for evaluation of video coding efficiency experiments

HSTP-VID-WPOM - Working practices using objective metrics for evaluation of video coding efficiency experiments




experiments

Electronic superhighway : from experiments in art and technology to art after the internet /

Library - Art Library, Location - OSIZ, Call number - FOLIO NX456.5.N49 E54 2016




experiments

From Coulomb’s force to magnetic force and experiments that show magnetic force parallel to current

Abstract: The Lorentz force law is fundamental for electromagnetism. However, it is known long ago that the Lorentz forces between two current elements do not respect the Newton’s third law. This seemingly harmless flaw had never been corrected. In physical sciences a discrepancy often hides in it new understanding or unexpected breakthrough. For solving this...




experiments

4 mind-bending math experiments that explain infinity

Can one infinity be bigger than another?




experiments

MSstatsTMT: Statistical Detection of Differentially Abundant Proteins in Experiments with Isobaric Labeling and Multiple Mixtures [Technological Innovation and Resources]

Tandem mass tag (TMT) is a multiplexing technology widely-used in proteomic research. It enables relative quantification of proteins from multiple biological samples in a single MS run with high efficiency and high throughput. However, experiments often require more biological replicates or conditions than can be accommodated by a single run, and involve multiple TMT mixtures and multiple runs. Such larger-scale experiments combine sources of biological and technical variation in patterns that are complex, unique to TMT-based workflows, and challenging for the downstream statistical analysis. These patterns cannot be adequately characterized by statistical methods designed for other technologies, such as label-free proteomics or transcriptomics. This manuscript proposes a general statistical approach for relative protein quantification in MS- based experiments with TMT labeling. It is applicable to experiments with multiple conditions, multiple biological replicate runs and multiple technical replicate runs, and unbalanced designs. It is based on a flexible family of linear mixed-effects models that handle complex patterns of technical artifacts and missing values. The approach is implemented in MSstatsTMT, a freely available open-source R/Bioconductor package compatible with data processing tools such as Proteome Discoverer, MaxQuant, OpenMS, and SpectroMine. Evaluation on a controlled mixture, simulated datasets, and three biological investigations with diverse designs demonstrated that MSstatsTMT balanced the sensitivity and the specificity of detecting differentially abundant proteins, in large-scale experiments with multiple biological mixtures.




experiments

"Experiments With David Atwood" by Artist Nam June Paik

A clip from the father of video art's 1969 piece




experiments

Cut the Rope: Experiments Review

Read the in depth Review of Cut the Rope: Experiments Gaming. Know detailed info about Cut the Rope: Experiments configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.




experiments

Five of the most important International Space Station experiments

From artificial retinas to ageing mice, here are five of the most promising results from research performed on the ISS – and what they might mean for humans on Earth and in space




experiments

Five of the most important International Space Station experiments

From artificial retinas to ageing mice, here are five of the most promising results from research performed on the ISS – and what they might mean for humans on Earth and in space




experiments

4 experiments with voice AI models to help you explore culture

Here are four AI voice models from Google Arts & Culture that offer a new way to experience and engage with art, history and culture.



  • Arts & Culture
  • AI

experiments

Conducting Experiments

Poke poke poke




experiments

Aging Experiments : Futures and Fantasies of Old Age [Electronic book] / João Paulo Guimarães.

[s.l.] : transcript Verlag, 2023.




experiments

Closed-loop identification of enzyme kinetics applying model-based design of experiments

React. Chem. Eng., 2024, 9,2984-2993
DOI: 10.1039/D4RE00127C, Paper
Leon Hennecke, Lucas Schaare, Mirko Skiborowski, Andreas Liese
This study presents an automated reactor platform for the identification of enzyme kinetic models using model-based design of experiments on the example of the reduction of NAD+ by formate dehydrogenase from Candida boidinii.
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experiments

Unveiling the dynamic CO2 capture performance of MgO promoted with molten salts and CaCO3 via fixed bed reactor experiments

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00432A, Paper
Open Access
Theodoros Papalas, Andy N. Antzaras, Angeliki A. Lemonidou
MgO promoted with molten alkali salts and CaCO3 displayed efficient CO2 capture activity in a fixed bed reactor, attaining 75% CO2 removal at 275 °C and stable cyclic performance, with the promoters providing an alternative carbonation mechanism.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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experiments

At K Sureshkumar’s pedagogical laboratory in Thiruvananthapuram students understand basic concepts of Physics by doing experiments on their own

National award-winning science teacher K Sureshkumar’s pedagogical laboratory in Thiruvananthapuram enables students of high school to conduct experiments in Physics and learn the concepts themselves



  • Life & Style

experiments

Maharashtra-based Indala Institute pledges against animal experiments, adopts simulation software

Spotlight on non-animal tools in education, says PETA calling for progressive science and research




experiments

A Sufficient Statistics Approach for Aggregating Firm-Level Experiments [electronic journal].

National Bureau of Economic Research




experiments

Reusing Natural Experiments [electronic journal].




experiments

Nano Reviews & Experiments [electronic journal].

Taylor & Francis




experiments

How to Improve Tax Compliance? Evidence from Population-wide Experiments in Belgium [electronic journal].




experiments

Historical Natural Experiments: Bridging Economics and Economic History [electronic journal].

National Bureau of Economic Research




experiments

Dynamic Legislative Bargaining with Veto Power: Theory and Experiments [electronic journal].




experiments

2020 21st International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (EuroSimE) [electronic journal].

IEEE / Institute of Electrical and Electronics Engineers Incorporated




experiments

His experiments in music

Musician Arun Varghese is keyed up about his work as a composer and sound designer




experiments

Interfacial viscoelasticity in oscillating drops of cyclodextrin-surfactant aqueous solution: experiments and theory

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01007H, Paper
José Roberto Romero-Arias, Alberto S. Luviano, Miguel Costas, Aurora Hernandez-Machado, Rafael A Barrio
We present experiments involving oscillating droplets in aqueous cyclodextrin-surfactant solutions. In these experiments, α-cyclodextrin (αCD) and anionic surfactants exhibit remarkable viscoelasticity at the liquid/air interface, with dilatational modulus varying across...
The content of this RSS Feed (c) The Royal Society of Chemistry