11/17/2024 - 1:30 PM - Venue: Rawlings Library

As of Nov. 13, the Crock-Pot 20-ounce electric lunch box is available at Amazon for $29.99, a $15 discount.

(EMAILWIRE.COM, November 01, 2024 ) Automotive Microcontrollers Market is expected to reach US$ 22.93 Bn. by 2030, at a CAGR of 8.2% during the forecast period. The automotive microcontroller market is experiencing significant growth, driven by the increasing integration of electronics in vehicles....

Published at LXer: The Pimoroni Pico Plus 2 W is an upgraded version of the RP2350 microcontroller, offering more memory and wireless connectivity while keeping the compact form factor of the...

Crockfords Casino Signup Bonus

Three hungry crocodiles were lying in the sun. One said, "I wish I could eat a young tender child."

Crochet, 25, was one of the top starting pitchers in the American League last season, posting a 3.58 ERA.

The post Red Sox viewed as a top candidate to land Garrett Crochet by pair of insiders appeared first on Boston.com.

Sarah Akinbuwa remembers the days when she was bullied over her love of crocheting, a hobby she picked up with her circle of schoolmates as a 12-year-old in Nigeria. Now living in Somerville and devoted to the craft, the 18-year-old is winning acclaim for one of her latest creations: a bright pink, floor-length prom dress […]

The post A Somerville teen crocheted her prom dress in three days. Her video of the design process went viral. appeared first on Boston.com.

With Garrett Crochet linked to the Red Sox as a potential trade candidate, John Tomase explains why the White Sox pitcher would be a great fit in Boston.

The monstrous terrorist attack at Crocus City Hall in Russia triggered discussions about the need to reinstate death penalty in the country. It is the legal side of the issue that is being discussed, since the moratorium was established by the Constitutional Court. Russian officials believe that the moratorium on the death penalty that was introduced in Russia in 1996 in connection with the entry into the Council of Europe should be suspended. State Duma speaker Vyacheslav Volodin believes that there is no need for any referendum here — it would only be enough for the Constitutional Court to lift it. Lawyers believe executions will return to Russia Experts maintain that according to the Constitutional Court's clarification from 2009, the binding nature of this or that political decision shall remain unchanged. However, the head of the State Duma Committee on Legislation, Pavel Krasheninnikov, said that there are grounds for lifting the moratorium.

The highly cytotoxic macrocyclic trichothecene Isororidin A (C29H40O9) was isolated from the fungus Myrothesium verrucaria endophytic on the wild medicinal plant `Datura' (Datura stramonium L.) and was characterized by one- (1D) and two-dimensional (2D) NMR spectroscopy. The three-dimensional structure of Isororidin A has been confirmed by X-ray crystallography at 0.81 Å resolution from crystals grown in the ortho­rhom­bic space group P212121, with one mol­ecule per asymmetric unit. Isororidin A is the epimer of previously described (by X-ray crystallography) Roridin A at position C-13' of the macrocyclic ring.

A considerable bottleneck in serial crystallography at XFEL and synchrotron sources is the efficient production of large quantities of homogenous, well diffracting microcrystals. Efficient high-throughput screening of batch-grown microcrystals and the determination of ground-state structures from different conditions is thus of considerable value in the early stages of a project. Here, a highly sample-efficient methodology to measure serial crystallography data from microcrystals by raster scanning within standard in situ 96-well crystallization plates is described. Structures were determined from very small quantities of microcrystal suspension and the results were compared with those from other sample-delivery methods. The analysis of a two-dimensional batch crystallization screen using this method is also described as a useful guide for further optimization and the selection of appropriate conditions for scaling up microcrystallization.

Eukaryotic TIR (Toll/interleukin-1 receptor protein) domains signal via TIR–TIR interactions, either by self-association or by interaction with other TIR domains. In mammals, TIR domains are found in Toll-like receptors (TLRs) and cytoplasmic adaptor proteins involved in pro-inflammatory signaling. Previous work revealed that the MAL TIR domain (MALTIR) nucleates the assembly of MyD88TIR into crystalline arrays in vitro. A microcrystal electron diffraction (MicroED) structure of the MyD88TIR assembly has previously been solved, revealing a two-stranded higher-order assembly of TIR domains. In this work, it is demonstrated that the TIR domain of TLR2, which is reported to signal as a heterodimer with either TLR1 or TLR6, induces the formation of crystalline higher-order assemblies of MyD88TIR in vitro, whereas TLR1TIR and TLR6TIR do not. Using an improved data-collection protocol, the MicroED structure of TLR2TIR-induced MyD88TIR microcrystals was determined at a higher resolution (2.85 Å) and with higher completeness (89%) compared with the previous structure of the MALTIR-induced MyD88TIR assembly. Both assemblies exhibit conformational differences in several areas that are important for signaling (for example the BB loop and CD loop) compared with their monomeric structures. These data suggest that TLR2TIR and MALTIR interact with MyD88 in an analogous manner during signaling, nucleating MyD88TIR assemblies uni­directionally.

X-ray crystallography is an established tool to probe the structure of macromolecules with atomic resolution. Compared with alternative techniques such as single-particle cryo-electron microscopy and micro-electron diffraction, X-ray crystallography is uniquely suited to room-temperature studies and for obtaining a detailed picture of macromolecules subjected to an external electric field (EEF). The impact of an EEF on proteins has been extensively explored through single-crystal X-ray crystallography, which works well with larger high-quality protein crystals. This article introduces a novel design for a 3D-printed in situ crystallization plate that serves a dual purpose: fostering crystal growth and allowing the concurrent examination of the effects of an EEF on crystals of varying sizes. The plate's compatibility with established X-ray crystallography techniques is evaluated.

The first-ever color-reveal cupcake and cookie dough pop mixes from Betty Crocker turn green for Elphaba or pink for Glinda.

The technology enables leading enterprises and data centers to realize the highest-performance Solid-State Drives (SSDs) utilizing next-generation NAND technologies.

Groundbreaking achievement by Safencap, an up and coming industry leader

Dec 8, 2024, 2pm EST

Join the TUAG Student Programming Committee for a crochet workshop with Leslie Rogers, SMFA at Tufts professor of the practice in sculpture. Taking inspiration from Tomashi Jackson’s use of fibers, knitwear, and woven elements in Across the Universe, Rogers will teach participants some basic techniques. Together, we can knit community via shared artmaking.

Building: Aidekman Arts Center
Campus Location: Medford/Somerville campus
City: Medford, MA 02155
Campus: Medford/Somerville campus
Location Details: Tufts Art Galleries, Aidekman Arts Center, Medford
Wheelchair Accessible (for in-person events): Yes
Open to Public: Yes
Primary Audience(s): Alumni and Friends, Faculty, Parents, Postdoctoral Fellows, Staff, Students (Graduate), Students (Undergraduate)
Event Type: Community Engagement, Exhibition, Lecture/Presentation/Seminar/Talk
Subject: Arts/Media, Education, Humanities
Event Sponsor: Tufts University Art Galleries
Event Sponsor Details: Generous support for Tufts University Art Galleries programming is provided by The Andy Warhol Foundation for the Visual Arts.
RSVP Information: Event is free and open to all. Please register here: www.eventbrite.com…
More info: artgalleries.tufts.edu…

This is the story behind one of the most valuable — and perhaps, most improbable — technologies humanity has ever created. It's a breakthrough called extreme ultraviolet lithography, and it's how the most advanced microchips in the world are made. The kind of chips powering the latest AI models. The kind of chips that the U.S. is desperately trying to keep out of the hands of China.

For years, few thought this technology was even possible. It still sounds like science fiction: A laser strong enough to blast holes in a bank vault hits a droplet of molten tin. The droplet explodes into a burst of extreme ultraviolet light. That precious light is funneled onto a wafer of silicon, where it etches circuits as fine as a strand of DNA. Only one company in the world that can make these advanced microchip etching machines: a Dutch firm called ASML.

Today on the show, how this breakthrough in advanced chipmaking happened — and how it almost didn't. How the long-shot idea was incubated in U.S. nuclear weapons laboratories and nurtured by U.S. tech giants. And, why a Dutch company now controls it.

This episode was hosted by Jeff Guo and Sally Helm. It was produced by Willa Rubin and edited by Jess Jiang. It was fact-checked by Dania Suleman, and engineered by Patrick Murray. Alex Goldmark is Planet Money's executive producer.

Help support Planet Money and hear our bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

Learn more about sponsor message choices: podcastchoices.com/adchoices

NPR Privacy Policy

Gatorland opens Croc Rock, a three-pronged adventure with rock climbing, a swinging bridge and zip line.

Gatorland introduces rock-climbing wall, Winchester the rescue alligator, three baby goats and future crocodile spot.

Comments

Siamese crocodile returns to Cambodia’s wild

Geopolitical tensions and technological constraints make the chip industry more complex to navigate. A groundbreaking engineer talks about it future.

A new collection of Body Stockings by MusicLegs®.

Crochet bodystocking with sexy spaghetti straps. Open crotch for convenience. Perfect to be worn under sexy evening dress with high heels shoes!

A new collection of crochet thigh highs with vinyl top, by MusicLegs®.

Unstretch pothole size 14x14mm.

A new collection of meshed pantyhose by MusicLegs®.

Fishnet pantyhose with side crocheted. Seamless fine fishnet mesh. Sexy pantyhose that is perfect for your favorite dress.

A new collection of bodystockings by MusicLegs®.

Lycra opaque sleeveless bodystocking with side crochet potholes and sexy spaghetti straps. Enhanced with precious Lycra for durability and elasticity.

A new collection of bodystockings by MusicLegs®.

Crotchless opaque bodystocking with side crochet design.

Onesize (5'~5'10", 100~175lbs).

Patterned pantyhose from Music Legs®. With crochet at ankle level. High spandex content for greater elasticity.

Onesize (5'~5'10", 100~175lbs).

If you've ever read the blog of Deerhunter, you probably realize that wild mood swings and prolificness are just par for the course. Brandon Cox has written epic rants and then apologize (or not), laying out feelings and thoughts in words that sometimes just seem like a grab for attention. At the same time that he does this, he posts new original songs (often under his solo guise Atlas Sound, which also released an album on Kranky earlier this year), videos, and mixes. Band member Lockett Pundt also releases songs there under the name Lotus Plaza, and he'll also release an album on Kranky next year. Needless to say, the group stays busy.

Nearly every powered device we use these days depends on microchips, from cars to electric guitars. A look at the origin of the integrated circuit, its rapid development, and the way this technology has changed the world's geopolitical and economic landscape.

Crocs is no stranger to headline-making collabs. Here are our favorites from the Broomfield-based footwear icon.

The strange way the world's fastest microchips are made This is the story behind one of the most valuable — and perhaps, most improbable — technologies humanity has ever created. It's a breakthrough called extreme ultraviolet lithography, and it's how the most advanced microchips in the world are…

It All Started with Hexie-lust!

Getting Hooked on Crochet

Original Crochet-Along, Frida's Flowers

Bored with making 6 identical flowers - Colors calling us!

Designing Our Afghans

Entering at the San Juan County Fair

With the fall season in full swing, a Business Insider reporter decided to make three cozy, comforting meals in a Crock-Pot.

Martin R. Larsen
Jul 1, 2005; 4:873-886
Technology

SLC19A2 and SLC19A3, also known as thiamine transporters (THTR) 1 and 2, respectively, transport the positively charged thiamine (vitamin B1) into cells to enable its efficient utilization. SLC19A2 and SLC19A3 are also known to transport structurally unrelated cationic drugs, such as metformin, but whether this charge selectivity extends to other molecules, such as pyridoxine (vitamin B6), is unknown. We tested this possibility using Madin-Darby canine kidney II (MDCKII) cells and human embryonic kidney 293 (HEK293) cells for transfection experiments, and also using Caco-2 cells as human intestinal epithelial model cells. The stable expression of SLC19A2 and SLC19A3 in MDCKII cells (as well as their transient expression in HEK293 cells) led to a significant induction in pyridoxine uptake at pH 5.5 compared with control cells. The induced uptake was pH-dependent, favoring acidic conditions over neutral to basic conditions, and protonophore-sensitive. It was saturable as a function of pyridoxine concentration, with an apparent Km of 37.8 and 18.5 μm, for SLC19A2 and SLC19A3, respectively, and inhibited by the pyridoxine analogs pyridoxal and pyridoxamine as well as thiamine. We also found that silencing the endogenous SLC19A3, but not SLC19A2, of Caco-2 cells with gene-specific siRNAs lead to a significant reduction in carrier-mediated pyridoxine uptake. These results show that SLC19A2 and SLC19A3 are capable of recognizing/transporting pyridoxine, favoring acidic conditions for operation, and suggest a possible role for these transporters in pyridoxine transport mainly in tissues with an acidic environment like the small intestine, which has an acidic surface microclimate.

CHANDLER, Ariz., Oct. 23, 2024 — The global edge computing market is expected to grow by more than 30 percent in the next five years, serving mission-critical applications in the […]

The post Microchip Expands 64-Bit Portfolio with High-Performance PIC64HX Microprocessors for Edge Computing appeared first on HPCwire.

More on the crocs at Smithsonian.com: http://j.mp/SWhbxZ The two Cuban crocodiles are the first for the zoo since 1988.

Margaret Wertheim talks about how math and climate change inspired her to start the Hyperbolic Crochet Coral Reef project. Read more at: https://www.smithsonianmag.com/arts-culture/how-to-crochet-a-coral-reef-69064479/

The beloved reptile in Australia died last weekend and was thought to be up to 120 years old, though that age is only an estimate. Research on his bones might reveal a more exact number

In Foxboro Green, a small retirement community in Baden, Ont., 30 women came together to create a 15-metre-long banner covered in small handmade poppies. CBC Kitchener-Waterloo's Cameron Mahler went to where they've displayed the banner ahead of Remembrance Day to find out more.