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Smithsonian scientists discover that rainforests take the heat

South American rainforests thrived during three extreme global warming events in the past, say paleontologists at the Smithsonian Tropical Research Institute in a new report […]

The post Smithsonian scientists discover that rainforests take the heat appeared first on Smithsonian Insider.




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Loss of animals spells doom for diversity of rainforest trees

Soon after a dirt road through the forests of Lambir Hills National Park in Borneo was improved in 1987, local markets selling the meat of […]

The post Loss of animals spells doom for diversity of rainforest trees appeared first on Smithsonian Insider.




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Rising temperatures mean more blooms for tropical rainforests

The North Pole isn’t the only place on Earth affected by slight increases in temperature. Until recently, scientific thinking used to posit that tropical forests, […]

The post Rising temperatures mean more blooms for tropical rainforests appeared first on Smithsonian Insider.




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Study: Managed beehives can discourage crop-raiding elephants

Strategically placed honeybee hives can deter African elephants from raiding crops, but the hives must be actively managed by beekeepers to work, according to a […]

The post Study: Managed beehives can discourage crop-raiding elephants appeared first on Smithsonian Insider.




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Microbes rule in ‘knee-high tropical rainforests’

Rainforests on infertile wet soils support more than half of all plant species. Shrublands on infertile dry soils in southwestern Australia, jokingly called “knee-high tropical […]

The post Microbes rule in ‘knee-high tropical rainforests’ appeared first on Smithsonian Insider.




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Smithsonian Scientists Discover Two New Gecko Species in Vanishing Myanmar Rainforest

Smithsonian scientists have discovered two new gecko species—the Lenya banded bent-toed gecko (Cyrtodactylus lenya) and Tenasserim Mountain bent-toed gecko (C. payarhtanesnsis)—in the little-studied lowland forests […]

The post Smithsonian Scientists Discover Two New Gecko Species in Vanishing Myanmar Rainforest appeared first on Smithsonian Insider.




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South Korea's fintech Toss aims to raise USD 200 mln investment

South Korea-based fintech startup Toss has planned to raise USD...




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New online training aims to ferret out child abuse cases in California schools

File: California school employees can now take their required training to spot child abuse and neglect by going online.; Credit: Cayoup/Flickr

Adolfo Guzman-Lopez

Public school employees can take their required annual training to spot child abuse or neglect online, California State Superintendent of Public Instruction Tom Torlakson announced Monday.

“Nothing is more important than the safety of our students,” Torlakson said in a written statement. “The new online training lessons will help school employees carry out their responsibilities to protect children and take action if they suspect abuse or neglect.”

A new California law requires school employees, including teachers, teacher aides, and substitute teachers, to show proof to their employers that they’ve taken the training.

“We were hearing anecdotally that there may have been suspicions of abuse and neglect that was not always reported and we wanted to do something about that issue,” said Stephanie Papas, a California Department of Education consultant.

Recent high-profile cases, such as that of former Miramonte Elementary teacher Mark Berndt, revealed that school employees failed to report allegations of abuse. Los Angeles Unified agreed to pay a record $140 million to settle claims filed by one group of students in the case and $30 million to a second group. Berndt is serving a 25-year sentence after pleading no contest to the charges of committing lewd acts on children.

Papas, who helped create the new two-hour online training, said the course will help employees tell if a child has been hurt from abuse or from an accident, for example.

“We have photos that are examples of, say, a welt that is in the shape of a belt buckle or a slap on a child’s cheek that’s left a hand imprint,” she said.

In-person trainings are more effective, she said, but they’re more expensive than online trainings. That pushed the Department of Education to provide the free online training for school districts still under budget constraints.

She said current employees have until this fall to show their school districts proof that they’ve taken the training.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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What's killing sea otters? Scientists pinpoint parasite strain

Full Text:

Many wild southern sea otters in California are infected with the parasite Toxoplasma gondii, yet the infection is fatal for only a fraction of sea otters, which has long puzzled the scientific community. A National Science Foundation-funded study identifies the parasite's specific strains that are killing southern sea otters, tracing them back to a bobcat and feral domestic cats from nearby watersheds. The study marks the first time a genetic link has been clearly established between the Toxoplasma strains in felid hosts and parasites causing fatal disease in marine wildlife. The study's results highlight how infectious agents like Toxoplasma can spread from cat feces on land to the sea, leading to detrimental impacts on marine wildlife.

Image credit: Trina Wood/UC Davis




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Horizon Therapeutics Shares Rise 15% on Strong Q1 Results and Raised F/Y Sales Guidance

Source: Streetwise Reports   05/06/2020

Shares of Horizon Therapeutics traded higher setting a new 52-week high price after the company reported a 27% y-o-y increase in net sales for Q1/20 and raised FY/20 net sales guidance.

Biopharmaceutical company Horizon Therapeutics Inc. (HZNP:NASDAQ), which focuses on developing and commercializing medicines for treatment of rare and rheumatic diseases, today announced its Q1/20 financial results for the period ending March 31, 2020. The firm began by advising that it is raising its FY/20 net sales guidance and revised its adjusted EBITDA guidance.

For Q1/20 the company reported that net sales increased by 27% to $355.9 million over Q1/19. The firm provided a breakdown of revenue by business unit and listed that in Q1/20 compared with Q1/19, its Orphan segment net sales increased 47% to $245.4 Million, KRYSTEXXA® net sales rose by 78% to $93.3 million and TEPEZZA (teprotumumab-trbw) net sales were $23.5 million, which exceeded expectations.

The firm advised that it is increasing FY/20 net sales guidance to $1.40-1.45 billion driven primarily by significantly higher TEPEZZA net sales and reflecting anticipated impacts from COVID-19. The company also presented revised FY/20 adjusted EBITDA guidance of $450-500 million, which reflects increased TEPEZZA program investment to support higher-than-expected demand.

The firm indicated that in Q1/20 it posted a GAAP net loss of $13.6 million with adjusted EBITDA of $107.2 million and non-GAAP net income of $83.2 million.

The company's Chairman, President and CEO Timothy Walbert commented, "We had a very strong start to 2020, highlighted by the early approval and rapid uptake of TEPEZZA, which significantly exceeded expectations, excellent KRYSTEXXA growth and our recent acquisition of HZN-825...We are increasing our full-year net sales guidance to account for significantly higher TEPEZZA net sales that more than offset the expected impact from COVID-19 this year, and we are widening both our net sales and adjusted EBITDA guidance ranges to account for future uncertainty. The fundamentals of our business are strong, including a robust cash position, and we continue to be very well positioned for the long term."

The company noted that it received FDA approval for TEPEZZA for the treatment of thyroid eye disease (TED) earlier this year in January. The firm described TED as "a rare, serious, progressive and vision-threatening autoimmune disease, and is associated with proptosis (eye bulging), diplopia (double vision), blurred vision, pain and facial disfigurement." The company further s explained that "TEPEZZA, a fully human monoclonal antibody insulin-like growth factor-1 receptor (IGF-1R) inhibitor, is the first and only FDA-approved medicine for the treatment of TED."

Horizon Therapeutics is a biopharmaceutical company headquartered in Dublin, Ireland. The firm researches, develops and commercializes medicines for treatment of rare and rheumatic diseases.

Horizon has a market capitalization of around $7.1 billion with approximately 190.2 million shares outstanding and a short interest of about 4.9%. HZNP shares opened 10% higher today at $44.19 (+$3.81, +10.19%) over yesterday's $37.38 closing price and reached a new 52-week high price this morning of $43.57. The stock has traded today between $40.00 and $43.90 per share and is currently trading at $42.95 (+$5.57, +14.90%).

Sign up for our FREE newsletter at: www.streetwisereports.com/get-news

Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees.
3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.
4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.
5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases.
6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice.




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Current Test-Based Incentive Programs Have Not Consistently Raised Student Achievement in U.S. - Improved Approaches Should Be Developed and Evaluated

Despite being used for several decades, test-based incentives have not consistently generated positive effects on student achievement, says a new report from the National Research Council.




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Raising Minimum Age to Buy Cigarettes to at Least 21 Will Reduce Smoking Prevalence and Save Lives, Says IOM

Increasing the minimum age of legal access (MLA) to tobacco products will prevent or delay initiation of tobacco use by adolescents and young adults, particularly those ages 15 to 17, and improve the health of Americans across the lifespan, says a new report from the Institute of Medicine.




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Young Adults Ages 18 to 26 Should Be Viewed as Separate Subpopulation - In ‘Critical Development Period,’ They Face Economic and Social Challenges While Brain Is Still Maturing, Says New Report

Young adults ages 18-26 should be viewed as a separate subpopulation in policy and research, because they are in a critical period of development when successes or failures could strongly affect the trajectories of their lives, says a new report from the Institute of Medicine and National Research Council.




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“G-Science” Academies Issue Statements on Strengthening Disaster Resilience, Protecting the Brain, and Nurturing Future Scientists

Today the science academies of the G7 countries and seven additional academies issued three joint statements to their respective governments to inform discussions during the G7 summit to be held in May in Japan, as well as ongoing policymaking.




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United States Skilled Technical Workforce Is Inadequate to Compete in Coming Decades - Actions Needed to Improve Education, Training, and Lifelong Learning of Workers

Policymakers, employers, and educational institutions should take steps to strengthen the nation’s skilled technical workforce, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Evaluating In-Service Performance of Guardrail End Treatments – New Report

The end of a roadside guardrail must be designed so that it is not a hazard to occupants of a vehicle striking it and so that it absorbs energy in a crash and redirects the vehicle into a safe trajectory.




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Concerns Remain Over Safety of Rail to Transport Energy Liquids and Gases

With the sharp and largely unexpected increase in the long-distance movement of domestically produced crude oil, ethanol, and natural gas since 2005, a number of concerns have arisen about the safe transport of these hazardous materials, particularly in relation to railroad track defects, rural communities’ emergency response preparedness, and the older tank car designs that will continue to be used in multi-car unit trains, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Public Transit Agencies Should Not Have to Disclose Safety Planning Records in Court, Similar to Laws for State Highway Agencies and Passenger Railroads, Says New Report

To enable public transit agencies to engage in more rigorous and effective safety planning, their safety planning records should not be admissible as evidence in civil litigation, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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VA’s Process for Determining Traumatic Brain Injury in Veterans Seeking Disability Compensation Examined in New Report

The U.S. Department of Veterans Affairs (VA) should expand the requirement in its disability compensation process regarding who can diagnose traumatic brain injury (TBI) to include any health care professional with pertinent and ongoing brain injury training and experience, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.




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New Report Finds K-12 Teachers Face New Expectations and More Demands - Training and Workforce Changes Could Help

A new report from the National Academies of Sciences, Engineering, and Medicine finds K-12 teachers face new expectations and more demands from policymakers, parents, students, and schools, including addressing changes in curriculum standards, the emergence of more explicit teaching goals, and shifts in what it means to support all students in their development.




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Henry Huntington: A Railroad Tycoon Who Transformed Southern California

Henry E. Huntington in 1907.; Credit: Theo C. Marceau, New York City. The Huntington Library, Art Museum, and Botanical Gardens

Brianna Flores

One of the most prized treasures of LA County is 100 years old this year.

The Huntington Library is beloved for its lush botanical gardens and fine art.

As KPCC's Brianna Flores reports, you can trace its origins to a pivotal moment in Southern California history.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Soil degradation: the impact of rainfall on soil condition

The status of soil can be represented by many properties. However, how well they represent soil status depends on the level of rainfall in the area. Researchers in Spain found that in wet regions soil status is strongly linked to biological factors, such as vegetation cover and biodiversity. In drier regions, status has a stronger link to the physical properties of the soil.




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AP Exams Are Still On Amid Coronavirus, Raising Questions About Fairness

; Credit: /Jackie Ferrentino for NPR

Carrie Jung | NPR

A lot is at stake for students taking Advanced Placement exams, even in normal times. If you score high enough, you can earn college credit. It's also a big factor in college applications. But for some students, the idea of studying right now feels impossible.

"I'm constantly thinking about making sure my family doesn't get sick and I don't get sick," says Elise, a high school junior outside Boston. (We're not using her full name because she's worried about hurting her college applications.)

Concerns about the coronavirus have put most standardized tests, such as the SAT and ACT, on hold this spring. But AP exams are going forward with a new online format — and that's raising questions about fairness.

Elise, 17, says she spent months preparing for what is typically a three-hour, multiple-choice and essay-based exam; she was blindsided when she learned it will now be an online, 45-minute, open-response test.

"I have no idea what I'm going to get when I open that test," she says.

Elise was hoping the College Board, which administers AP exams, would cancel this year's exams, as it did the spring SATs. But since the tests are being offered, she says she feels she has to take them. She worries it would look bad on her college applications if she opted out.

For other students, just the idea of taking the exam at home is causing anxiety. Kayleen Guzman, 17, from Boston says it's hard to find peace and quiet in her house right now.

"Currently, it's me, my mom, my dog, my sister and my stepdad," she explains. "Sometimes I feel like it's too much chaos."

But Guzman is glad she still has the opportunity to take the AP exams at all this year. She says she worked hard in her two AP classes and she wants the chance to earn college credit.

However, it's still unclear how much credit colleges will give students for this year's exams.

"None of us would say that we are confident that a 3 or 4 or 5 on the AP exam this year means the exact same thing as a 3, 4 and 5 on the exam last year," says Harvard University's Andrew Ho, who studies the reliability of educational tests.

Ho says that because of the new format, this year's AP exams won't be measuring the same thing as previous years' exams. For one, the new tests will cover less material. And changing where kids take it — from a proctored classroom to their laptops at home — is a big deal. But Ho adds, "Just because it's not completely comparable doesn't mean the College Board and colleges, through their own policies, couldn't adjust."

Some colleges are already adjusting. The University of California system has come out explicitly to say it won't change the way it credits AP scores. Other colleges that didn't want to go on the record say they are planning to change their policies, but the details weren't ready to share just yet.

In a statement, College Board spokesperson Jerome White said the organization decided to move forward with AP testing to give motivated students the opportunity to earn college credit. He added that the organization is making "a significant financial investment" to make the exams available online, from cheating prevention software to helping students who may not have an Internet connection or access to a computer.

Still, some educators worry that those efforts won't be enough.

"This situation has created a lot of distraction," says Savannah Lodge-Scharff, an AP Physics teacher for Boston Public Schools. She argues that without in-person classes, many students won't be able to engage with the material in the same way. On top of that, financial stress means many of her students are juggling additional responsibilities, like taking care of siblings.

"I have some of my students who are working 40, 50, 60 hours a week at the grocery store right now in the fear their parents are going to be laid off," she explains.

And then there's the question of geographic equity. This year's exams will be administered at the same time worldwide, meaning students in Hong Kong will be up at midnight to take it.

Copyright 2020 WBUR. To see more, visit WBUR.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Patt's Hats: Raid your grandmother's closet!

; Credit: Michelle Lanz/KPCC

Patt Morrison

From brights the other day to mutes today. You could call this color palette "blush and sand," which sounds like the title of a romance novel with a Valentino lookalike on the cover!

This is exactly the kind of sweater I used to tease my grandmother about wearing, the elaborately beaded 1950s cardigans that you saw on everyone from Babe Paley to Lucille Ball to … your grandmother

Of course, now I wish I had more of them! The best are the silk-lined cashmere or merino wool ones made in what was, for more than 150 years, the British Crown Colony of Hong Kong. The work of Hong Kong tailors is legendary, and now all the 1950s and early 1960s pieces are enjoying a tremendous vogue.

In this case the colors – bronze, blush and sand – are hushed, which lets the beading look more pronounced. The sleeveless top is a silk jersey criss-crossed with stitched bands of darker silk chiffon. King’s X? And then the skirt is bias-cut chiffon in very quiet hues. If designers gave quirky names to prints the way cosmetics makers do to lipstick and cheek color, we could call this one, "Shhh! This is a library!’"

So I’m glad that the shoes get paroled to holler. The nude patent color is ladylike, not loud, which is why I’m surprised but gratified that it’s hung around for a couple of seasons now. It’s a very versatile hue, even if it’s not making it as Pantone's color of the year.

No, the troublemaker part of this ensemble is the jeweled heels. Paul Simon sang of diamonds on the soles of one’s shoes; these are big dazzling rhinestones on the heels of mine. They gleam, they coruscate, they twinkle, they flash – amid all these well-behaved quiet colors, they send out a wink and a message that "I’m really a lively girl at heart, and at my feet."

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Governor signs bill raising Hollywood tax credits

In this file photo, California Gov. Jerry Brown speaks during a news conference on January 17, 2014 in San Francisco, California. Brown on Thursday signed a bill that more than triples the state's annual tax credit for film and TV production to $330 million.; Credit: Justin Sullivan/Getty Images

Gov. Jerry Brown has headed to the cradle of the Hollywood film industry to sign legislation that more than triples the state's annual tax credit to $330 million a year for films and TV shows produced in California.

Brown says the increase is needed to help prevent other states and countries from hijacking film and TV production by offering their own lucrative incentives.

Brown signed the bill Thursday at the former Grauman's Chinese Theatre, where handprints and footprints of stars from the eras of Humphrey Bogart to Robert De Niro are embedded in concrete.

Under the new system, credit will be awarded based on the number of jobs a production creates and its overall positive impact on the state.

The historic cinema is now called the TCL Chinese Theatre IMAX.

Film tax credit doc




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Libeo raises EUR 4 mln to automate invoicing for companies

Libeo, a France-based fintech startup that simplifies the...




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Axis Bank to raise USD 4.6 bln amid COVID-19

India-based Axis Bank has announced it is planning to raise...





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Ninja Van raises USD 279 mln after ecommerce surge

Singapore-based logistics provider Ninja Van has raised USD...




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Back Market raises USD 120 mln for its marketplace

The France-based startup Back Market has raised a new USD...




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West Pharma Services' Shares Rise 10% on Q1 Sales Growth and Raised FY Earnings Guidance

Source: Streetwise Reports   04/23/2020

Shares of West Pharmaceutical Services traded higher and established a new 52-week high price after the firm reported Q1/20 earnings that included a 10.8% increase in YoY revenues.

Global healthcare packaging components manufacturer company West Pharmaceutical Services Inc. (WST:NYSE) today announced financial results for its first quarter ending March 31, 2020 and provided updated full-year 2020 financial guidance.

The company reported that net sales in Q1/20 increased to $491.5 million, a 10.8% increase from $443.5 million in Q1/19. During the same corresponding period, the firm stated that non-GAAP diluted earnings per share (EPS) increased by 36% to $0.99 and non-GAAP adjusted-diluted EPS increased by 36% to $1.01.

West Pharmaceutical Services advised that it is maintaining its FY/20 net sales guidance, which is expected to be in a range of $1.95-1.97 billion. The company stated that it is updating FY/20 adjusted-diluted EPS guidance to a new range of $3.52-3.62, compared to the prior estimated range of $3.45-3.55.

The company's President and CEO Eric M. Green commented, "During these unprecedented times, our priorities are focused on the well-being and safety of our team members as well as ensuring the supply of critical, high-quality components and solutions to our customers...I am extremely pleased that we delivered a strong performance in the first quarter given the challenging environment that the COVID-19 pandemic has had on our customers, our suppliers and our team members. In particular, we continued to deliver strong sales growth in high-value products, as demand trends from our worldwide customer base were similar to trends we saw last year. Our teams are partnering with a broad range of customers working to support efforts to develop solutions that address the global COVID-19 pandemic such as diagnostics, anti-viral therapeutics and vaccines."

The firm outlined sales in the most recent quarter by product line. The company reported that in Q1/20, net sales in its Proprietary Products segment grew by 9.7% to $373.5 million and that this segment "saw good demand for Westar®, Daikyo®, NovaPure® and FluroTec® components as well as for devices such as Daikyo Crystal Zenith® syringes and cartridges and our self-injection platforms."

The firm noted that net sales from its Contract-Manufactured Products segment grew by 14.5% to $118.1 million led by sales of components for diagnostic devices and drug-injection delivery devices.

The company added that the Biologics market unit enjoyed double-digit organic sales growth, the Generics market unit achieved high-single digit organic sales growth and the Pharma market unit registered mid-single digit organic sales growth.

The firm additionally noted that during Q1/20 under its share repurchase program, it repurchased 761,500 shares for $115.5 million at an average share price of $151.65.

West Pharmaceutical Services is headquartered in Exton, Pa., roughly 35 miles west of Philadelphia, and is a designer and manufacturer of injectable pharmaceutical packaging and delivery systems.

West Pharmaceutical has market capitalization of around $13.5 billion with approximately 73.84 million shares outstanding. WST shares opened 5.25% higher today at $179.05 (+$8.93, +5.25%) over yesterday's $170.12 closing price and reached a new 52-week high price this morning of $190.27. The stock has traded today between $177.13 and $190.27 per share and is currently trading at $187.04 (+$17.17, +10.11%).

Sign up for our FREE newsletter at: www.streetwisereports.com/get-news

Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees.
3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.
4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.
5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases.
6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice.

( Companies Mentioned: WST:NYSE, )




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Horizon Therapeutics Shares Rise 15% on Strong Q1 Results and Raised F/Y Sales Guidance

Source: Streetwise Reports   05/06/2020

Shares of Horizon Therapeutics traded higher setting a new 52-week high price after the company reported a 27% y-o-y increase in net sales for Q1/20 and raised FY/20 net sales guidance.

Biopharmaceutical company Horizon Therapeutics Inc. (HZNP:NASDAQ), which focuses on developing and commercializing medicines for treatment of rare and rheumatic diseases, today announced its Q1/20 financial results for the period ending March 31, 2020. The firm began by advising that it is raising its FY/20 net sales guidance and revised its adjusted EBITDA guidance.

For Q1/20 the company reported that net sales increased by 27% to $355.9 million over Q1/19. The firm provided a breakdown of revenue by business unit and listed that in Q1/20 compared with Q1/19, its Orphan segment net sales increased 47% to $245.4 Million, KRYSTEXXA® net sales rose by 78% to $93.3 million and TEPEZZA (teprotumumab-trbw) net sales were $23.5 million, which exceeded expectations.

The firm advised that it is increasing FY/20 net sales guidance to $1.40-1.45 billion driven primarily by significantly higher TEPEZZA net sales and reflecting anticipated impacts from COVID-19. The company also presented revised FY/20 adjusted EBITDA guidance of $450-500 million, which reflects increased TEPEZZA program investment to support higher-than-expected demand.

The firm indicated that in Q1/20 it posted a GAAP net loss of $13.6 million with adjusted EBITDA of $107.2 million and non-GAAP net income of $83.2 million.

The company's Chairman, President and CEO Timothy Walbert commented, "We had a very strong start to 2020, highlighted by the early approval and rapid uptake of TEPEZZA, which significantly exceeded expectations, excellent KRYSTEXXA growth and our recent acquisition of HZN-825...We are increasing our full-year net sales guidance to account for significantly higher TEPEZZA net sales that more than offset the expected impact from COVID-19 this year, and we are widening both our net sales and adjusted EBITDA guidance ranges to account for future uncertainty. The fundamentals of our business are strong, including a robust cash position, and we continue to be very well positioned for the long term."

The company noted that it received FDA approval for TEPEZZA for the treatment of thyroid eye disease (TED) earlier this year in January. The firm described TED as "a rare, serious, progressive and vision-threatening autoimmune disease, and is associated with proptosis (eye bulging), diplopia (double vision), blurred vision, pain and facial disfigurement." The company further s explained that "TEPEZZA, a fully human monoclonal antibody insulin-like growth factor-1 receptor (IGF-1R) inhibitor, is the first and only FDA-approved medicine for the treatment of TED."

Horizon Therapeutics is a biopharmaceutical company headquartered in Dublin, Ireland. The firm researches, develops and commercializes medicines for treatment of rare and rheumatic diseases.

Horizon has a market capitalization of around $7.1 billion with approximately 190.2 million shares outstanding and a short interest of about 4.9%. HZNP shares opened 10% higher today at $44.19 (+$3.81, +10.19%) over yesterday's $37.38 closing price and reached a new 52-week high price this morning of $43.57. The stock has traded today between $40.00 and $43.90 per share and is currently trading at $42.95 (+$5.57, +14.90%).

Sign up for our FREE newsletter at: www.streetwisereports.com/get-news

Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees.
3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.
4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.
5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases.
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Episode 961 Scott Adams: Flynn, Freedom, Vitamin D, Biden’s Brain and More

My new book LOSERTHINK, available now on Amazon https://tinyurl.com/rqmjc2a Content: There WAS…a genuine coup attempt Governor Abbott’s Coronavirus strategy CNN promotes their choice for Biden’s VP Hoaxes, hoaxes and hoaxes Vitamin D and groups vulnerable to coronavirus If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on […]

The post Episode 961 Scott Adams: Flynn, Freedom, Vitamin D, Biden’s Brain and More appeared first on Scott Adams' Blog.




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Road and rail infrastructure threaten Sweden’s protected birds

In Sweden, 63% of areas designated as Special Protection Areas (SPAs) for endangered birds are impacted by major roads or train lines, according to a new study. The research showed that 126 000 hectares (ha), or 4.2% of the SPAs, fall within 1 km of a road or train line, leading to a predicted 1% loss in bird abundance. The problem is greater in the south of the country, where 25.8% of land designated as SPA falls within 1 km of a road or rail line, representing an estimated 4 to 7% reduction in birds’ abundance within SPAs.




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Rail vehicle manufacturer Stadler hit by cyberattack, blackmailed

International rail vehicle construction company, Stadler, disclosed that it was the victim of a cyberattack which might have also allowed the attackers to steal company and employee data. [...]




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More information and training on green public procurement could increase its uptake

Public authorities in EU Member States are encouraged to purchase more environmentally-friendly goods and services through Green Public Procurement (GPP). A recent survey of purchasing managers in Italy has identified some factors that influence their adoption of this strategy, and suggests that a broad knowledge of GPP is key to its implementation.




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Antibody reduces harmful brain amyloid plaques in Alzheimer's patients

Although the causes of Alzheimer's disease are still unknown, it is clear that the disease commences with progressive amyloid deposition in the brains of affected persons between ten and fifteen years before the emergence of initial clinical symptoms such as memory loss. Researchers have now been able to show that Aducanumab, a human monoclonal antibody, selectively binds brain amyloid plaques, thus enabling microglial cells to remove the plaques. A one-year treatment with the antibody, as part of a phase Ib study, resulted in almost complete clearance of the brain amyloid plaques in the study group patients. The results, which were realized by researchers at UZH together with the biotech company "Biogen" and the UZH spin-off "Neurimmune," have been published in the renowned science journal "Nature."

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  • Health & Medicine

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Study details Zika virus disrupting fetal brain development during pregnancy

For the first time, abnormal brain development following a Zika infection during pregnancy has been documented experimentally in the offspring of a non-human primate.

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  • Health & Medicine

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Global biomass potential under sustainable constraints

Biomass is increasingly used to make biofuels and generate electricity and is seen as a valuable source of renewable energy. A recent study has assessed the key factors relating to the sustainability of bioenergy production and suggests global biomass could potentially meet up to one third of the projected global energy demand in 2050.




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How does drained peatland respond to wildfire?

Wildfires could release up to nine times more stored carbon from drained peatland at high latitudes than from untouched peatland in the same region, according to a recent study. As climate change is expected to both dry out peatland and increase the frequency of wildfires, the results have serious implications for the role of northern peatlands as carbon sinks or sources.




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Screening soil moisture conditions reveals an increased risk of drought in a Swedish drainage basin

The risk of drought in the Norrström drainage basin, Sweden, increased during the 20th century, a new study has found. As the frequency of the dry periods increased, less water was available in the landscape for agriculture and for the resupply of groundwater — despite an increase in precipitation in the area over the same period. The researchers reached this conclusion after screening soil moisture conditions in the basin over the course of the century.




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Mukesh Ambani isn't letting a lockdown derail his plans of tech domination

The flurry of transactions show the tycoon's ambitions to pivot Reliance Industries into an Indian technology titan are going into hyperdrive




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NASA sees Tropical Depression Rai over Thailand, Vietnam, Laos

After Tropical Depression 19W moved ashore in central Vietnam NASA-NOAA's Suomi NPP satellite passed over the system and found some powerful thunderstorms over Thailand, Vietnam and Laos capable of dropping heavy rainfall.

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  • Astronomy & Space

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Raising the profile of soil’s essential contribution to society

Soils play a vital role in the Earth's life-support system, yet their importance and value to society is not always recognised. A recent study suggests that incorporating soils into a National Capital and Ecosystem Services framework will raise the profile of soils and enable soils to be more easily integrated into policy decisions.




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Chew on this: How we believe our meat is raised can influence how it tastes

Our beliefs about how farm animals are raised can shape our meat-eating experience, according to a new study led by Lisa Feldman Barrett, University Distinguished Professor of Psychology at Northeastern University.

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  • Psychology & Sociology

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Dog brains process both what we say and how we say it

The first study to investigate how dog brains process speech shows that our best friends in the animal kingdom care about both what we say and how we say it. Dogs, like people, use the left hemisphere to process words, a right hemisphere brain region to process intonation, and praising activates dog's reward center only when both words and intonation match, according to a study in Science.

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  • Psychology & Sociology

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Personnel selection, training could mitigate effects of cognitive lock-up in automation operators

Automation failures have been the cause of such widely reported disasters as the crash of Air France Flight 447 in 2009, with most of the focus placed on deficiencies in the automated system. Although automation does help in avoiding human error in completing tasks, people are still needed to monitor how well the automated system is operating.

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  • Psychology & Sociology

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What makes railway noise annoying? Research investigates

A new study into the impact of railway noise has revealed that it is not just the level of noise that contributes to annoyance for local residents, but also the number of trains and the vibrations they cause. As railway transport is likely to increase in coming years, plans are needed to reduce these effects.




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Long-term exposure to railway noise linked to reduced cognitive performance

Residents living near a busy railway line in Strasbourg were found by researchers to have reduced cognitive function compared to residents in quieter areas, which may be the result of long-term exposure to night-time noise. Psychological tests suggested that they had not adapted to the noise over the years, and they did not become less affected with time.




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Climate change and transport: effects of sea-level rise on an English railway line

Climate change will have major consequences for transport networks, especially those located on coastlines. This study assessed the impact of projected sea-level rise on a vulnerable stretch of railway line on the coast of South West England. The authors say their semi-empirical modelling method could provide guidance to policymakers worldwide.