tal Pre-Election Pep Talk from Kevin Jackson – Part II By theblacksphere.net Published On :: Mon, 04 Nov 2024 18:46:12 +0000 The following article, Pre-Election Pep Talk from Kevin Jackson – Part II, was first published on The Black Sphere. Soon Conservatives will have much to celebrate, though many still fear the outcome of the election. Thus, I am reminding America of what’s about to happen. Continue reading Pre-Election Pep Talk from Kevin Jackson – Part II ... Full Article Featured Politics
tal 'The cash came up to my torso' - tales of a match-fixer By www.bbc.com Published On :: Mon, 09 Sep 2024 23:02:31 GMT Moses Swaibu was one of the brightest prospects in Crystal Palace's youth ranks, but he ended up in a shady world of cash, danger and fixing rather than football's limelight. Full Article
tal 'Generational' young England talents excite O'Shea By www.bbc.com Published On :: Tue, 12 Nov 2024 06:45:37 GMT England have a "generational" crop of talent that has more potential than the squad that reached the 2019 World Cup final, says Rugby Football Union director of performance Conor O'Shea. Full Article
tal How close were hospitals to collapse in Covid? By www.bbc.com Published On :: Mon, 28 Oct 2024 00:06:04 GMT The Covid inquiry restarts its live hearings this week, after senior staff in the NHS revealed just how close some hospitals were to collapse Full Article
tal BBC tours hospital Israel says sits above millions in Hezbollah gold By www.bbc.com Published On :: Tue, 22 Oct 2024 09:06:04 GMT The BBC’s Orla Guerin is taken on a tour of Al Sahel Hospital in Beirut. Full Article
tal F1 in 10 Years: Norris says keeping 'sound and smell' is vital By www.bbc.com Published On :: Wed, 31 Jul 2024 09:06:14 GMT McLaren's Lando Norris talks to BBC Sport about why he wants Formula One to retain the "sound and smell" that first sparked his love for the sport. Full Article
tal Inside a hospital on the front line of Sudan’s hunger crisis By www.bbc.com Published On :: Wed, 02 Oct 2024 23:17:37 GMT One of the worst famines in decades could be underway in Sudan, aid workers warn. Full Article
tal Learn how to say Wales' tallest mountain in Welsh By www.bbc.com Published On :: Tue, 12 Nov 2024 18:18:52 GMT How to say the Welsh names for the mountain formerly known as Snowdon - and the park where it sits. Full Article
tal Should You Install A Gun Safe In The Basement? By patriotoutdoornews.com Published On :: Sun, 03 Dec 2023 05:41:53 +0000 The basement is a good place to store large gun safes if you don’t want them to be seen easily. Since your basement is inside your house and you can better monitor it, it also provides greater security than your garage. There are many similarities between basement gun safes and garage gun safes. It will […] The post Should You Install A Gun Safe In The Basement? appeared first on Patriot Outdoor News. Full Article Gear & Accessories
tal Trump Halts COVID-19 Relief Bill Talks Until After Election By hispolitica.com Published On :: Tue, 06 Oct 2020 20:36:18 +0000 President Trump on Tuesday instructed his administration to stop negotiating with House Speaker Nancy Pelosi (D-CA) on future coronavirus stimulus relief package until after the November election. In a series of four tweets, Trump called out Pelosi for not “negotiating in good faith” by wanting a $2.4 Trillion stimulus package that focuses on funding issues […] The post Trump Halts COVID-19 Relief Bill Talks Until After Election appeared first on Hispolitica. Full Article President Donald Trump U.S. Congress 2020 2020 elections Amy Coney Barrett CARES Act chuck schumer congress Coronavirus Coronavirus Relief Coronavirus Relief Package covid-19 Federal Reserve House Jerome Powell Joe Biden Kevin McCarthy Mark Meadows mitch mcconnell nancy pelosi president trump Steven Mnuchin Stimulus Package Stock Market
tal Italian authorities bust 'Banksy forgery ring' By www.bbc.com Published On :: Mon, 11 Nov 2024 17:31:15 GMT Over 2,100 forgeries, also targeting Warhol, Picasso, Monet and Dali, were recovered in the sting. Full Article
tal Herschel Grynszpan And the Untold Story Of Kristallnacht By lidblog.com Published On :: Mon, 11 Nov 2024 01:33:04 +0000 By Shimshon Cook, Herut Zionist, Texas U.S. On the night of NNovember 9 1938, all across Nazi Germany, ] an organized pogrom was perpetrated against the Jewish population by Nazis in an event now known as Kristallnacht. They stretched from Germany proper and annexed Austria and Sudetenland in what was Czechoslovakia. 30,000+ Jewish men were “arrested” […] The post Herschel Grynszpan And the Untold Story Of Kristallnacht appeared first on The Lid. Full Article antisemitism Holocaust Kristallnacht Shoah
tal News24 | Iran says it will pursue 'its interest' when asked about possibility of Trump talks By www.news24.com Published On :: Tuesday Nov 12 2024 12:28:48 Iran will pursue whatever secures its interest, government spokesperson Fatemeh Mohajerani said on Tuesday, when asked if there could be direct talks with the Trump administration. Full Article
tal velocityconf: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/Z0EetiQshZ By twitter.com Published On :: Thu, 23 May 2013 17:35:35 +0000 velocityconf: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/Z0EetiQshZ Full Article
tal velocityconf: Who's up for a 5 minute lightning talk. Last day to get your #Ignite proposal in for #velocityconf CA. http://t.co/pzL0WJtQH5 By twitter.com Published On :: Wed, 29 May 2013 14:11:50 +0000 velocityconf: Who's up for a 5 minute lightning talk. Last day to get your #Ignite proposal in for #velocityconf CA. http://t.co/pzL0WJtQH5 Full Article
tal News24 | INTERVIEW | 'Rock star without an instrument': Booker-winner Shehan Karunatilaka talks Seven Moons By www.news24.com Published On :: Wednesday Nov 13 2024 05:01:31 "I realised I could sustain the writing life, whether anyone reads it or not. It’s what separates writers from civilians. It’s probably a mental disorder." Full Article
tal News24 | Booker Prize 2024: Samantha Harvey's Orbital soars with astronauts' earth reflections By www.news24.com Published On :: Wednesday Nov 13 2024 09:00:20 Samantha Harvey's Orbital wins the Booker Prize. The 136-page space novel explores astronauts' reflections on Earth, touching on mourning, desire, and the climate crisis. Full Article
tal How to Install Windows 11 on Mac with UTM By osxdaily.com Published On :: Thu, 07 Nov 2024 16:47:25 +0000 You can install and run Windows 11 on a Mac, without having to overwrite the MacOS operating system, by installing Windows 11 into a virtual machine. Virtual machines are self-contained installations of operating systems that can be used for a variety of purposes, from testing to demonstrations, to running software that runs on Windows but ... Read More Full Article Mac OS Tips & Tricks Mac macOS run Windows on Mac tips tricks UTM virtual machine virtualization windows Windows 11 Windows on Mac
tal 4 parenting priorities to prevent mental health 'summer slide' By www.kqed.org Published On :: Fri, 30 Jun 2023 09:12:06 EDT With school on break, along with all the homework, tests and early start times that come with it, parents often assume that young people’s stress and anxiety will take a pause as well. However, that’s not always the case, especially as the novelty of summer dwindles. Without the daily structure of school and extracurricular activities, kids may struggle with boredom or restlessness. Maintaining a routine during the summer can be a powerful tool for supporting children’s mental health, and parents can play a crucial role in establishing and reinforcing this structure. Full Article
tal I helped Tom Cruise and other celebrities divorce, but I've been happily married for 38 years. I've learned that dates — and postnups — can be key to marital bliss. By www.businessinsider.com Published On :: Tue, 12 Nov 2024 19:47:01 +0000 Marilyn Chinitz has worked with celebs like Tom Cruise, Michael Douglas, and Wendy Williams. She has been happily married for 38 years. Full Article Health as-told-to health health-freelancer sex-and-relationships divorce
tal Jude Law is married to a psychologist and says talking about feelings helps maintain their 'healthy relationship' By www.businessinsider.com Published On :: Wed, 13 Nov 2024 03:30:20 +0000 Jude Law added that people in middle age should start to reflect on their relationship patterns. Full Article Health Entertainment relationship celebrity-relationships jude-law communication relationship-advice psychology
tal Three Benefits of Promoting Digital Goods and Software Products By blog.avangate.com Published On :: Thu, 20 Dec 2018 00:00:00 +0000 Are you dreaming of being your own boss someday, or would you like to bring in extra income? Starting an online business is one of the easiest ways to accomplish this. The biggest challenge of starting an online business can be developing your business plan. If you are struggling to come up with that brilliant […] Full Article
tal The Efficacy of Digital Media Resources in Improving Children’s Ability to Use Informational Text: An Evaluation of Molly of Denali From PBS KIDS By www.readingrockets.org Published On :: Wed, 31 Aug 2022 14:08:03 EDT Informational text — resources whose purpose is to inform — is essential to daily life and fundamental to literacy. Unfortunately, young children typically have limited exposure to informational text. Two 9-week randomized controlled trials with 263 first-grade children from low-income communities examined whether free educational videos and digital games from the PBS KIDS show “Molly of Denali” supported children’s ability to use informational text to answer real-world questions. Study 1 found significant positive intervention impacts on child outcomes; Study 2 replicated these findings. Full Article
tal Flockerz Capitalizes on Bitcoin Rally, Raising $1.6M in Presale By readwrite.com Published On :: Tue, 12 Nov 2024 19:16:11 +0000 Bitcoin has been reaching new all-time highs almost daily, fueling a parabolic bull run that’s pushing various cryptocurrencies to surge… Continue reading Flockerz Capitalizes on Bitcoin Rally, Raising $1.6M in Presale The post Flockerz Capitalizes on Bitcoin Rally, Raising $1.6M in Presale appeared first on ReadWrite. Full Article Cryptocurrency
tal News24 | Patients lie on the floor at Uitenhage hospital - some with serious injuries By www.news24.com Published On :: Tuesday Nov 12 2024 19:38:05 Patients lie on the floor at Uitenhage Provincial Hospital in Kariega, some with drips in their veins. Full Article
tal Video: Merlin's Time & Attention Talk (Improvised Rutgers Edition) By www.43folders.com Published On :: Tue, 27 Apr 2010 19:57:09 +0000 Video: Merlin Mann - "Time & Attention Talk (improvised)" Audio (mp3): "Merlin Mann - 'Rutgers Time & Attention Talk'" This is a talk I did at Rutgers earlier this month. I kinda like it, but for a weird reason. Something something, perfect storm of technology Ragnarok, and yadda yadda, I had to start the talk 20 minutes late with no slides. Nothing. So, I riffed. And, I ended up talking about a lot of the new stuff you can expect to see in the Inbox Zero book—work culture, managing expectations, the 3 deadly qualities of email, and one surprising reason email's not as much fun as Project Runway. Some people liked it. I think. I liked it. I hope you do, too. Here's the slides I would have shown. ;-) Who Moved My Brain? Revaluing Time & Attention Many thanks, again, to my great pal, Dr. Donald Schaffner, for bringing me in for this visit. I had a great time and met some fantastic, passionate people. Much appreciated. Hey—know anybody who should hear this talk? Hmmm? I’ll bet. Lucky you, you can hire me to deliver this or any of my other talks to the time- and attention-addled people you work with as well. Current topics include email, meetings, social media, and future-proofing your passion. Drop a note if you have an upcoming event where you think we two might be a good fit. update 2010-04-27_13-50-00 Apologies—my friends at Rutgers (inexplicably) have placed this video under lock and key. Fortunately, I have a lock-picker called Firefox. Samizdat video available soon... update 2010-04-27_14-42-24 Yay, fixed! Many thanks to my hero, Jesse Schibilia. ”Video: Merlin's Time & Attention Talk (Improvised Rutgers Edition)” was written by Merlin Mann for 43Folders.com and was originally posted on April 27, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Time and Attention Videos world of work
tal Visiting Locorotondo, Italy – A Guide to the Trulli Town By www.adventurouskate.com Published On :: Wed, 21 Aug 2024 15:59:03 +0000 Have you heard of Locorotondo, Italy? Locorotondo is one of Southern Italy’s most beautiful villages, in my opinion, but it isn’t yet overwhelmed with tourist crowds. A true hidden gem, Locorotondo is just a 12-minute drive from busy Alberobello in the Puglia region, but feels like a world away. Planning your trip to Locorotondo last […] The post Visiting Locorotondo, Italy – A Guide to the Trulli Town appeared first on Adventurous Kate. Full Article Italy puglia
tal 30+ Epic Things to Do in Rome, Italy By www.adventurouskate.com Published On :: Tue, 27 Aug 2024 15:41:41 +0000 Rome is magnificent in every way possible, from the millennia of history made here to the deliciousness of a perfect cacio e pepe pasta. There are so many things to do in Rome, from the Colosseum to the Vatican Museums to the Trevi Fountain and the Spanish Steps. Rome is so overwhelming, in a good […] The post 30+ Epic Things to Do in Rome, Italy appeared first on Adventurous Kate. Full Article Italy
tal Guide to the 5 Towns of Cinque Terre, Italy By www.adventurouskate.com Published On :: Thu, 05 Sep 2024 14:38:24 +0000 Cinque Terre is one of the most picturesque regions in Italy. These steep, colorful fishing villages perched on seaside cliffs of the Italian Riviera will take your breath away! There are 5 towns of Cinque Terre: Monterosso al Mare, Vernazza, Corniglia, Manarola, and Riomaggiore. Here you’ll find my recommendations for all five towns, plus the […] The post Guide to the 5 Towns of Cinque Terre, Italy appeared first on Adventurous Kate. Full Article Italy
tal 16 Cool Things to Do in Siena, Italy By www.adventurouskate.com Published On :: Thu, 07 Nov 2024 17:29:57 +0000 There are so many fantastic things to do in Siena, Italy. This small city in Tuscany is an excellent day trip from Florence, showcasing the beauty of urban Italy, with far fewer tourists than in Florence. Many tourists visit Siena on a day trip from nearby Florence — and it’s even better when paired with […] The post 16 Cool Things to Do in Siena, Italy appeared first on Adventurous Kate. Full Article Italy
tal 16 Fun Things to Do in Pisa, Italy By www.adventurouskate.com Published On :: Sat, 09 Nov 2024 12:28:00 +0000 There’s so much more to Pisa than the Leaning Tower. There are so many cool things to do in Pisa — this is a big, bustling city with a mind and attitude of its own! So many travelers swoop in on a day trip from Florence to take photos with the Leaning Tower of Pisa. And […] The post 16 Fun Things to Do in Pisa, Italy appeared first on Adventurous Kate. Full Article Italy
tal A.F. Branco cartoon – Genital Madness By comicallyincorrect.com Published On :: Tue, 22 Oct 2024 11:00:47 +0000 A.F. Branco Cartoon – Democrats, the party of child genital mutilation and late-term abortion, are outraged at Trump for his comments alluding to.. Full Article Political Cartoons Trump
tal On-Air Talent Will Not Be Spared as CNN Prepares Mass Layoffs in Wake of Election: Report By www.westernjournal.com Published On :: Tue, 12 Nov 2024 23:36:38 +0000 CNN reportedly will be making more cuts in the near future, including to its highly paid on-air personalities, following poor election ratings. The New York Post reported that Fox News […] The post On-Air Talent Will Not Be Spared as CNN Prepares Mass Layoffs in Wake of Election: Report appeared first on The Western Journal. Full Article News 2024 election CNN Entertainment Establishment media Liberal media Media bias Politics Television
tal Commentary: The Tale of Two Conventions By deneenborelli.com Published On :: Fri, 23 Aug 2024 20:09:01 +0000 Commentary by Newt Gingrich originally published by RealClearPolicy and RealClearWire Historians will look at the 2024 Democratic and Republican national conventions as harbingers of profound changes in American politics and government. Callista and I participated in the Republican National Convention in Milwaukee, so we got a good sense of who was there and what was … Full Article Commentaries News
tal Investigation: Waste of the Day – Florida Hospitals Spent $566 Million Caring for Illegal Immigrants By deneenborelli.com Published On :: Tue, 01 Oct 2024 20:25:26 +0000 Investigation by Jeremy Portnoy originally published by RealClearInvestigations and RealClearWire Topline: Florida hospitals spent $566 million providing care for illegal immigrants in the last six months of 2023, according to a recent report from the state’s Agency for Healthcare Administration. Key facts: Gov. Ron DeSantis passed a law in May 2023 instructing all hospitals that … Full Article Commentaries Government Policies News
tal No infinite spin for planar total collision By www.ams.org Published On :: Wed, 16 Oct 2024 14:24 EDT Richard Moeckel and Richard Montgomery J. Amer. Math. Soc. 38 (), 225-241. Abstract, references and article information Full Article
tal Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography [Enzymology] By www.jbc.org Published On :: 2020-12-11T00:06:21-08:00 The main protease (3CL Mpro) from SARS–CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL Mpro possesses an unusual catalytic dyad composed of Cys145 and His41 residues. A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active-site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus. Here, we present the room-temperature neutron structure of 3CL Mpro, which allowed direct determination of hydrogen atom positions and, hence, protonation states in the protease. We observe that the catalytic site natively adopts a zwitterionic reactive form in which Cys145 is in the negatively charged thiolate state and His41 is doubly protonated and positively charged, instead of the neutral unreactive state usually envisaged. The neutron structure also identified the protonation states, and thus electrical charges, of all other amino acid residues and revealed intricate hydrogen-bonding networks in the active-site cavity and at the dimer interface. The fine atomic details present in this structure were made possible by the unique scattering properties of the neutron, which is an ideal probe for locating hydrogen positions and experimentally determining protonation states at near-physiological temperature. Our observations provide critical information for structure-assisted and computational drug design, allowing precise tailoring of inhibitors to the enzyme's electrostatic environment. Full Article
tal A Digital India Must Embrace the Circular Economy By www.chathamhouse.org Published On :: Mon, 15 Jan 2018 10:48:13 +0000 A Digital India Must Embrace the Circular Economy Expert comment sysadmin 15 January 2018 A growing amount of e-waste should draw attention to the broader sustainability of a digital society. — Workers dismantle old computers at an e-waste recycling factory near Bangalore. Photo: Getty Images. The latest Global E-Waste Monitor places India as one of the highest contributors to global e-waste, generating over 2 million metric tonnes in 2016. Posing serious health and environmental risks, growing e-waste represents the hidden cost of increasingly digital lives in an information society. With just 33 per cent of the population owning a smart phone, India already has the second largest number of smart phone users in the world, nearly 4 times that of the United States. The amount of e-waste generated will exponentially increase in the coming decade as the cost of consumer electronics decline, middle-class incomes rise, and the frequency at which devices are discarded increases. As governance instruments are increasingly digitized and industry re-repositions itself to leverage Industry 4.0 solutions, the generation of e-waste will become a byproduct of institutional choices rather than consumer consumption and behaviour alone. India is already a leader in the management and recycling of e-waste. But over 90 per cent is managed in the unorganized sector by small businesses and individual entrepreneurs, typically from low-income marginalized communities, and often women. E-waste contains various toxic substances such as mercury and lead, prolonged exposure to which can lead to major health problems. Almost 80 per cent of e-waste workers in India suffer from respiratory ailments due to improper standards and nearly 500,000 children are engaged in e-waste collection without adequate protection and safeguards. The bulk of the dirty and dangerous work supporting India’s march towards an increasingly digital society is done by those who have the least access to technology gains. Government regulations for the management of e-waste, on the other hand, are becoming more relaxed, presumably as a result of industry pressure. To streamline e-waste management, the government notified Electronic Waste Rules in 2011, based on the concept of extended producer responsibility (EPR). EPR makes manufacturers of electronic products responsible for the end-of-life management of their products, including setting up collection centres. By shifting the burden to manufacturers, the EPR framework, in theory, creates incentives for more environmentally friendly design. But the impact of EPR rules on manufacturers has been minimal, at best. The recently released Draft Notification (2017) by the Ministry of Environment, Forest and Climate Change further relaxes the EPR rule by reducing the e-waste collection targets for industries. While the efficiency and productivity gains of Digital India are to be welcomed, growing e-waste should draw attention to the broader sustainability of a digital society. Data centres, for example, are one the largest contributors to global warming, contributing a similar amount to global greenhouse emissions as the aviation industry. This amount is expected to triple in the next decade. In many ways, the sustainability challenge is a ‘wicked problem’ – where possible solutions create a new set of additional challenges and the choice between available alternatives is largely about competing values. For example, data centres powered by renewable sources of energy such as solar provide a greener alternative, but will also create new forms of e-waste in the form of photovoltaic cells and panels. An unverified estimate suggests that India’s projected solar capacity of 100 gigawatts by 2022 will create 7.76 million tonnes of e-waste. Without adequate and preemptive consideration of how this waste should be disposed and recycled, renewable energy solutions can create new negative externalities. For Digital India to be sustainable, we need to develop anticipatory knowledge for preemptive solutions. It is an opportune moment to think of the broader architecture of a digital society, one that avoids getting locked into unsustainable models of production and consumption, as is the case with many industrialized economies. The argument that such considerations are premature for India, given high levels of poverty and unemployment, are misplaced. Enquiries into the sustainability of Digital India are no less urgent than the need for sustained job-creating economic growth. These issues should not be addressed in a sequential or linear manner, but in parallel, or else we will be only partially aware of available choices and their consequences, creating new forms of technological and economic lock-ins. The value-based choice demanded by the ‘wicked problem’ at hand is one that embraces the idea of a circular economy — one that departs from the linear economic growth model predicated on ‘take, make, dispose’ to embrace a growth model based on creating closed loops of production, consumption and re-use. A circular economy model is built on the idea of designing out waste and pollution; keeping products and materials in use; and regenerating natural systems. In many ways, India is already a leader in the circular economy. Alongside, the management of e-waste and other forms of recycling, high levels of repair and reuse are distinctly observable. A number of reports note that the informal waste management sector in India works better than systems in many industrialized economies. A circular economy vision for Digital India would include organizing informal waste management systems, including safety and social protection initiatives for workers; revising and tightening existent e-waste rules for increased accountability by manufacturers both in terms of durable design and responsible disposal; green data centres; and building future smart cities with a view towards energy and water efficiency, among others. A recent report by the Ellen McArthur Foundation and the World Economic Forum also estimates that a circular economy path to development could bring India annual benefits of $624 billion by 2050. Greenhouse gas emissions could also be 44 per cent lower in 2050, compared with current development path. Unsurprisingly, Nordic countries are leading the way in promoting the idea of a circular economy. Sweden recently announced tax breaks for repair related activities and Finland hosted the first global conference on the circular economy earlier this year. The circular economy provides an opportunity for India to capitalize and leverage an already existing culture of circular activities, and promote it as a policy agenda that will create new forms of employment while facilitating sustainable environmental management. This article was originally published in the Indian Express. Full Article
tal Digital politics threatens democracy and must change By www.chathamhouse.org Published On :: Fri, 13 Jan 2023 16:08:06 +0000 Digital politics threatens democracy and must change Expert comment NCapeling 13 January 2023 Violence in Brazil has again brought into focus the need for technology platforms to prioritize social responsibility to help prevent anti-democratic action. Immediately following the violent storming of Brazil’s congressional building, supreme court, and presidential palace, comparisons to the infamous events of 6 January 2021 in the US came quickly and easily – and with good reason. Both Donald Trump and Jair Bolsonaro built a fervent – albeit inchoate – political base of grievance which included Christian evangelicals, gun enthusiasts, and the disenfranchised. Both cynically spread doubts about the election victories of their successors without evidence. And it has been claimed both incited their supporters to overturn these results. But this list of similarities extend beyond mere politics. The attack on democracy in Brazil was recorded, amplified, coordinated, and funded by exactly the same technologies used by the protesters in the US on 6 January. In Brazil, the main engines of misinformation and insurrection planning were Telegram, Facebook, and WhatsApp, although some election-denying diehards also shifted to Twitter. Tactical use of social media to mobilize and fundraise When Bolsonaro was originally elected in 2018, these platforms were already a medium for promoting disinformation, conspiracy, and fear. But in the lead-up to the violence of 8 January, they became a means by which ‘Bolsonaristas’ raised funding for an attack and mobilized supporters to come to Brasilia – advertising the availability of buses and even free food for marchers – using the Festa da Selma hashtag. Well-intentioned regulation will fall short so long as it is narrowly focused on a never-ending game of ‘content whack-a-mole’ and is hamstrung by powerful voices To avoid detection by authorities, organizers used a simple switch of the letter ‘v’ to ‘m’ so that Selva, meaning ‘jungle’, became Selma – which means ‘party in the jungle’ to those in the know. But the authorities in the Brasilia state of Distrito Federal appeared to care little about preventing the attack anyway. Civil society organizations have warned for decades that policies made in a Silicon Valley boardroom fit poorly to the realities of countries such as Brazil, Somalia, or Myanmar. Content moderation is a near-impossible task at the scale demanded by platforms as vast as those operated by big tech, and automated solutions are far from being a silver bullet as they create as many problems as they solve. Extremism has found an unfettered enabler on mainstream platforms, and an increasingly sprawling network of alternative tech has made such voices resilient to challenge. Platforms such as Gettr, Gab, and Telegram have become go-to platforms for extremist networks when fringe voices find themselves blocked by mainstream platforms. Telegram has come under significant scrutiny for the role it played in the storming of Congress in Brasilia but any number of tools and platforms – each with millions of users – could have achieved similar results. The sordid events in Brasilia are just the latest chapter in digital extremism and conspiracy- mongering which often erupts into anti-democratic violence, and should serve as a reminder of the urgent risks of disinformation and the role digital technology plays in inciting, coordinating, fundraising, and amplifying such events. But the checks on the power of private social media companies are still few and splintered. In Brazil, Supreme Court Justice Alexandre de Moraes, head of the elections tribunal, attempted to crack down on social media, banning users for spreading misinformation in a move which sparked complaints of censorship from Bolsonaro supporters. Following the elections, Moraes has advocated for greater judicial authority to regulate social media – but the justice is only one person and his impartiality is already being challenged given his aggressive pursuit of Bolsonaro supporters posting inflammatory messages. And one justice doing it alone only inflames an already volatile situation. Effective regulation of social media requires an independent body vested with multiparty support and operating under clearly-defined rules and authority. A global movement to find solutions Brazil is not alone in an increasingly frantic search for checks on digital power as dozens of regulatory regimes are springing up around the world. All are premised on platforms being responsible for their own fiefdoms, but few tackle the threat posed to democracy by unchecked corporate power over digital commons. Telegram has come under significant scrutiny for the role it played in the storming of Congress in Brasilia but any number of tools and platforms – each with millions of users – could have achieved similar results Well-intentioned regulation will fall short so long as it is narrowly focused on a never-ending game of ‘content whack-a-mole’ and is hamstrung by powerful voices who see any rules as an attack on freedoms of expression or corporate decision-making. Democracies are traditionally cautious in managing speech, in separating good information from bad information, or in defining acceptable politics. The steady watering down of the UK’s Online Safety Bill, now so thin on disinformation as to be essentially homeopathic, shows that democratic regulation is willing to go only so far in tackling challenges posed by digital politics. Full Article
tal The aftermath: Navigating a Taliban-led Afghanistan By www.chathamhouse.org Published On :: Fri, 20 Aug 2021 10:38:43 +0000 The aftermath: Navigating a Taliban-led Afghanistan Expert comment NCapeling 20 August 2021 In the coming weeks, governments and international organizations must work through an approach to the Taliban takeover of Afghanistan. It will not be simple. A failure to acknowledge that the legitimate, elected representatives of Afghanistan are no longer in control of territory or institutions, and to refuse to deal with those that are, will only make for further misery for a population which has already endured decades of violence and poverty. But to recognize the Taliban risks condemning tens of thousands of Afghan women, children, and men to brutal repression and, for some, potential death, as well as mocking the human rights and rule of law which the US and its allies sought to promote in Afghanistan, and globally, as cornerstones of values-based foreign policies. The dilemma western governments find themselves in is one they have studiously sought to avoid despite mounting evidence that, without a negotiated deal, a Taliban takeover was only a matter of time. As late as 6 August, the UN Security Council refused to countenance appeals by the UN mission and Afghan civil society activists to press the Taliban and the government to negotiate a ceasefire. The US reiterated its refrain that it ‘will not accept a military takeover of Afghanistan’ and the UK stressed the Taliban’s only route to power was through meaningful engagement in a peace process. Meanwhile, not until 11 August did Germany and the Netherlands stop deporting Afghan migrants despite the pleas of Afghan authorities and refugee organizations that the country was on the brink of crisis. Delaying the inevitable Belief that a military takeover was still some months away may have led diplomats to view dealing with the Taliban as a distant task. The unilateral nature of the US deal with the Taliban and the resistance of the Ghani government to any suggestion of power-sharing arrangements compounded a lack of international coordination and planning on what the conditions for engagement might be. Formal recognition of a Taliban-led government is simply not an option, even for those maintaining a diplomatic presence in Kabul such as China, Iran, Pakistan, and Russia It cannot be delayed further. The scale of the humanitarian crisis in Afghanistan is daunting, with more than half a million displaced by fighting in 2021 alone, almost 17 million facing crisis levels of food insecurity, and nearly half of all children under five malnourished as a consequence of drought and the COVID-19 pandemic. With one of the highest global refugee populations and an estimated up 20-30,000 Afghans fleeing the country weekly – even before the government collapsed – Afghanistan evokes still raw memories of the 2015 Syria migrant crisis for Europe. Pakistan and Turkey, home to some of the largest Afghan refugee communities, have already closed their borders to more. The ongoing chaos at Kabul airport highlights the challenges ahead. But there is a small window – before the UN Security Council is scheduled to review the mandate of the UN mission in Afghanistan by 17 September – for the US and its allies to craft an approach to dealing with the Taliban. Formal recognition of a Taliban-led government is simply not an option, even for those maintaining a diplomatic presence in Kabul such as China, Iran, Pakistan, and Russia. Technically the Afghan republic has not yet dissolved with vice-president Amrullah Saleh, reportedly in hiding in the Panjshir valley, claiming he is the country’s ‘caretaker’ president. Conditions for international acceptance Afghanistan’s ‘enduring partners’ must now focus on building a consensus around five conditions for international acceptance of a Taliban-administered Afghanistan and prevent the Taliban again reaping the benefits of international divisions. The G7 began to articulate some of these conditions but they need to be set out and negotiated with Afghanistan’s neighbours before being formally articulated by the UN Security Council. Adherence to Afghanistan’s human rights obligations. This must specify the rights of women and girls to education and work, the protection of ethnic and religious minorities, and safe passage for all Afghans and internationals leaving the country. Amnesty for all individuals who worked for the Afghan government or international embassies, forces, or aid organizations since 2001. No harbouring of terrorist groups. This has been the central condition for the US deal with the Taliban, and the overriding concern for both China and Russia. Non-lethal public order. The provision of public order to enable supply routes to open, evacuations to continue, and aid to be delivered, is essential and one that Russia has made as a condition for its future relations. Negotiation of inclusive political arrangements with Afghanistan’s political and ethnic factions. Belief that a military takeover was still some months away may have led diplomats to view dealing with the Taliban as a distant task The UN mission in Afghanistan, including its human rights component, and the Al-Qaida Sanctions Committee’s Analytical Support and Sanctions Monitoring Team should be mandated with reporting monthly on the progress toward these five conditions. Their assessments should form the basis for any reconsideration of the Taliban’s status as a terrorist organization. And a negotiated political settlement must be a precondition to the release of the government’s foreign reserves, estimated to be $9.5 billion. Before this, the humanitarian and development aid on which Afghanistan is almost completely reliant must be recalibrated to flow through international agencies. Models such as Hamas-run Gaza, Assad’s Syria, or Aristide’s Haiti, show that while far from effective, it is possible to provide urgent assistance outside government channels. Subscribe to our weekly newsletterOur flagship newsletter provides a weekly round-up of content, plus receive the latest on events and how to connect with the institute. Enter email address Subscribe This is one of the reasons why the Taliban has sought to retain a strong UN presence across Afghanistan and why the UN must be given a more significant political mandate and resources. The World Bank-administered Afghan Reconstruction Trust Fund should remain the principal channel for international funds. It is difficult in the short-term to see the US leading this collective effort, given its defensive and domestic-focused position. It could be a moment for the UK and EU to demonstrate their multilateral commitments and forge a coordinated conditions-based approach to a Taliban-administered Afghanistan at the UN. Going beyond handwringing or gesture politics will be difficult and messy and, ultimately, Afghanistan’s future must be decided by Afghans. Until that day, however, this will save lives. Full Article
tal Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the line 66 model of frontotemporal dementia [Molecular Bases of Disease] By www.jbc.org Published On :: 2020-12-25T00:06:31-08:00 Synapse loss is associated with motor and cognitive decline in multiple neurodegenerative disorders, and the cellular redistribution of tau is related to synaptic impairment in tauopathies, such as Alzheimer's disease and frontotemporal dementia. Here, we examined the cellular distribution of tau protein species in human tau overexpressing line 66 mice, a transgenic mouse model akin to genetic variants of frontotemporal dementia. Line 66 mice express intracellular tau aggregates in multiple brain regions and exhibit sensorimotor and motor learning deficiencies. Using a series of anti-tau antibodies, we observed, histologically, that nonphosphorylated transgenic human tau is enriched in synapses, whereas phosphorylated tau accumulates predominantly in cell bodies and axons. Subcellular fractionation confirmed that human tau is highly enriched in insoluble cytosolic and synaptosomal fractions, whereas endogenous mouse tau is virtually absent from synapses. Cytosolic tau was resistant to solubilization with urea and Triton X-100, indicating the formation of larger tau aggregates. By contrast, synaptic tau was partially soluble after Triton X-100 treatment and most likely represents aggregates of smaller size. MS corroborated that synaptosomal tau is nonphosphorylated. Tau enriched in the synapse of line 66 mice, therefore, appears to be in an oligomeric and nonphosphorylated state, and one that could have a direct impact on cognitive function. Full Article
tal Harris and Trump's shared goal masks a fundamental AI policy divide By www.chathamhouse.org Published On :: Sun, 03 Nov 2024 16:38:49 +0000 Harris and Trump's shared goal masks a fundamental AI policy divide Expert comment rgold.drupal 3 November 2024 Both presidential candidates will pursue US tech dominance but differ on the means to achieve it. There remain some differences between the US presidential candidates’ positions on the governance of artificial intelligence and other emerging technology, notably around competition. But under either future administration, US decision-making looks set to be heavily influenced by growing securitization, the aims of the US technology industry and broader competition with China. ‘Safe’ AI development Related content The US election will take place in a polluted information space Vice President Kamala Harris attended the inaugural Global AI Safety summit in the UK in 2023, where she announced President Joe Biden’s Executive Order on AI. This significant move by the federal government sought to define national and cyber security guidelines for AI developers and outline privacy and transparency guarantees. It also committed the federal government to a review of the National Security implications of this emerging technology, which was published last week.In her remarks at the summit, Harris was clear that her definitions of safety extended beyond catastrophic risk mitigation to societal and personal harm. She noted the corrosive effects of some algorithmic decision-making and disinformation on democracy, appealing for AI that is developed ‘in the service of the public interest’.A number of initiatives developed during the Biden administration have attempted to steer emerging technology as it takes root in society. This includes the establishment of the US AI Safety Institute, various schemes on global AI governance and investment in Public AI projects like the National AI Research Resource (NAIRR).The US public is largely supportive: polling by the AI Policy Institute (AIPI) points to a majority preference for safety standards governing the US effort to lead in AI, rather than pedal-to-the-metal development. Investment in public options on AI and the infrastructure required to develop and sustain it is a bold direction that the incoming administration should consider expanding.Biden’s Executive Order on AI has come under fire by the Trump campaign. At a rally in Iowa, Trump explained that he would cancel the order ‘on day one’, echoing a Republican platform that described it as imposing ‘Radical Leftwing ideas’ . While the candidates may disagree on the role of the federal government in setting standards, there will be close alignment on the central need for US supremacy in national security. Trump does, however, have his own track record in technology policy. During his first presidency, his administration passed an Executive Order on AI, stressing that ‘continued American leadership in Artificial Intelligence is of paramount importance to maintaining the economic and national security of the United States’. The tools and institutions announced as part of the order – including AI research investment, national AI research institutes and AI regulatory guidance including on federal use of AI – echo those of the current administration. Four years is a long time in AI, however. As the power of this technology is revealed, talk of safety may give way to talk of security. While the candidates may disagree on the role of the federal government in setting standards, there will be close alignment on the central need for US supremacy in national security. Neither administration seems likely to erect barriers to securitization of AI should it emerge as a critical strategic asset.AI regulation at home American industry will remain the pivotal force shaping the US AI ecosystem, particularly as America jostles for position as the maker of the global rules governing AI. A notable aspect of Biden’s AI Executive Order was where it staked responsibility. Reports by AI and Cloud companies on the safety of their tools and infrastructure are sent to the Department of Commerce.Under Secretary Gina Raimondo, whose star continues to rise, the department has become significantly more engaged with technology companies. In the absence of any other legal authority, AI governance has therefore sat under the purview of a secretary who herself has noted that they are ‘not a regulator’. The trend of industry leaders driving the government agenda on AI is replicated in other departments. There was an outcry over the composition of the new Department of Homeland Security advisory panel, the Artificial Intelligence and Security Board, with civil society groups concerned about the preponderance of industry voices: the 22-member panel includes the CEOs of OpenAI, Anthropic, NVIDIA, IBM, AWS, Adobe, Microsoft and Alphabet.Under a Harris presidency, these trends seem likely to continue. Plus with deadlock in Congress probable, establishing new legal authorities for emerging technology will be difficult. That will likely mean emerging tech governance remains heavily influenced by the Department for Commerce. The Biden administration has courted the CEOs of AI companies who have historically spoken out in favour of regulation. Trump’s allies tend towards a more deregulatory agenda. Like Harris, Trump has his allies in industry. While the Biden administration has courted the CEOs of AI companies who have historically spoken out in favour of regulation, Trump’s allies tend towards a more deregulatory agenda. Silicon Valley billionaires Elon Musk and Marc Andreessen have backed Trump’s plans to minimize AI regulation, lauding his support for ‘little tech’. They have also backed reported plans for so-called ‘Manhattan Projects’ to develop military technology, stewarded by ‘industry-led’ agencies. Trump’s aversion to strong regulatory institutions may mean an end to Biden’s anti-trust efforts, benefitting the biggest voices in the room, though his VP pick may disagree. JD Vance has somewhat surprisingly come out strongly in defence of the current chair of the Federal Trade Commission, Lina Khan, and her anti-trust efforts targeting US big tech.Regardless, business interests will likely shape either a Harris or Trump administration’s approach as the US grapples with balancing the ambitions of its industry with an increasingly protectionist stance towards its biggest import market, China.Competition abroadChina looms large in the imaginations of both campaigns. The US has signalled to its allies that American AI standards should replace Chinese standards. Export controls on semiconductors were expanded in September this year, with key voices in the industry – notably the Netherlands, Japan and South Korea – describing the restrictions as ‘economically motivated’ despite nominally being tied to national security by the US. Full Article
tal Corporations and Environmental Sustainability: Profit vs Planet? By f1.media.brightcove.com Published On :: Fri, 13 Apr 2018 00:00:00 +0100 Full Article
tal Undercurrents: Episode 9 - Digital Subversion in Cyberspace, and Oleg Sentsov's Hunger Strike By f1.media.brightcove.com Published On :: Fri, 01 Jun 2018 00:00:00 +0100 Full Article
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tal Undercurrents: Summer Special - Andrés Rozental on Mexican Politics By f1.media.brightcove.com Published On :: Thu, 01 Aug 2019 00:00:00 +0100 Full Article
tal Technology Diplomacy in the Digital Age By f1.media.brightcove.com Published On :: Wed, 11 Dec 2019 00:00:00 +0000 Full Article
tal The Digital Revolution: How Do We Ensure No One Is Left Behind? By f1.media.brightcove.com Published On :: Thu, 30 Jan 2020 00:00:00 +0000 Full Article