Self-medication with over-the-counter (OTC) analgesics, particularly paracetamol (PCM), among children is widespread and increasing. Parents often administer the medicine. The health care system has little knowledge or possibility to regulate OTC medication, and use of PCM for children may be partly unjustified.

Maternal frequent self-medication with OTC analgesics is associated with frequent use of OTC analgesics, particularly PCM, among 6- to 11-year-old schoolchildren, even when the child’s frequency of pain is accounted for. (Read the full article)

Several studies suggest that excessive media use in early childhood predicts poorer developmental outcomes. It has not been studied whether infants with self-regulation problems, who may be at higher developmental risk, develop excessive media use habits.

This study shows that infants and toddlers with self-regulation difficulties (ie, problems with self-soothing, sleep, emotional regulation, and attention) view more media at 2 years of age, independent of other important confounders. (Read the full article)

In-person peer counseling to pregnant and new mothers has been shown to improve breastfeeding modestly in three US RCTs. But this level of support for WIC is unlikely to be scaled up nationally in the current fiscal environment.

We randomly assigned WIC clients to a telephone peer counseling program relative to standard WIC support for breastfeeding. Nonexclusive breastfeeding among Spanish-speakers increased at 1, 3, and 6 months, but the program had much less of an effect on English-speaking clients. (Read the full article)

Recent reviews suggest that children bullied by siblings are at increased risk of internalizing symptoms. It is not known whether being bullied by a sibling increases risk of psychiatric disorders such as depression, anxiety, and self-harm.

Using a large, community-based birth cohort, we found that being bullied by a sibling is prospectively associated with a doubling in the odds of both depression and self-harm at 18 years in young adults. (Read the full article)

Restrictive feeding by parents is associated with poorer eating self-regulation and increased child weight status. However, this association could be due to confounding home environmental or genetic factors that are challenging to control.

Differential maternal restrictive feeding is associated with differences in twins' caloric compensation and BMI z score. Controlling for the shared home environment and partially for genetics, these findings further support a true (ie, unconfounded) association between restriction and childhood obesity. (Read the full article)

Studies have shown that setbacks, such as receiving low school grades, lead children to experience negative self-feelings (eg, shame, insecurity, powerlessness). Psychological theory predicts that unconditional regard can buffer this adverse impact of setbacks. However, causal evidence is lacking.

This randomized field experiment shows that briefly reflecting on experiences of unconditional regard buffers children’s negative self-feelings after an academic setback 3 weeks later. Unconditional regard may thus be an important psychological lever to reduce negative self-feelings in youth. (Read the full article)

Research suggests that appearance-focused messages and exaggerated depictions of sexual activity in the media negatively influence adolescents’ body and sexual self-perceptions. As adolescents increasingly use the Internet to explore their sexuality, health risks related to online behaviors should be identified.

This 4-wave study examined the prevalence and development of 2 receptive and 2 interactive sex-related online behaviors and their relations with adolescents’ body and sexual self-perceptions. It further investigated which parental strategies regarding Internet use may reduce risky sex-related online behaviors. (Read the full article)

A previous study suggested that physicians in 1 practice network were less likely to diagnose otitis media (OM) and to prescribe broad-spectrum antibiotics for OM for black versus nonblack children.

Nationally, black children with OM are more likely to receive guideline-recommended, narrow-spectrum antibiotics than nonblack children. These findings may reflect inappropriate treatment of OM with the use of broad-spectrum antibiotics in a majority of US children. (Read the full article)

Many population-based studies including pubertal children are based on self-assessment of pubertal maturation, the reliability of which is uncertain.

Self-assessment is not reliable for precise pubertal staging. Simple distinctions between prepuberty and puberty showed moderate agreement with clinical examinations. Parents and girls tended to underestimate and boys to overestimate pubertal development by up to 50% and 30%, respectively. (Read the full article)

Exclusive breastfeeding until 6 months of an infant’s age is described as the safest, most powerful and cost-effective intervention to reduce infant morbidity and mortality globally. In developing countries, only ~25% of infants are exclusively breastfed for 6 months.

We developed a psycho-educational intervention combining education with techniques of cognitive-behavioral therapy, integrated it into the routine work of community health workers, which increased the rate and duration of exclusive breastfeeding until 6 months of an infant’s age. (Read the full article)

Childhood obesity rates in the United States remain at historic highs. The pediatric primary care office represents an important, underutilized source of intervention. There is a need to test the efficacy of motivational interviewing for pediatric obesity in primary care.

This is among the first large-scale randomized trials to show significant reductions in BMI and that motivational interviewing, delivered by trained providers in the primary care setting, can be an important and feasible part of addressing childhood obesity. (Read the full article)

Self-harm behavior is a major public health problem and a leading cause of death in adolescents. The majority of patients who self-injure do not die, but they are at increased risk for a successful future suicide attempt.

Emergency department visits for self-inflicted injuries in adolescents increased from 2009 to 2012, whereas visits for self-inflicted firearm injuries decreased. The presence of any comorbid condition increased risk for self-harm, indicating that increased attempts at prevention may be warranted in these young people. (Read the full article)

Selective eating is a common, burdensome eating pattern in young children. A significant subset remain selective eaters at least until adolescence and, for some, adulthood. The question is whether selective eating is a serious enough developmental pattern to warrant intervention.

This study examines whether selective eating, at 2 levels of severity, is associated with current and future psychological problems. Because moderate levels of selective eating were associated with impairment, selective eating falls within the diagnosis of avoidant/restrictive food intake disorder. (Read the full article)

On Thursday, the company sent an email to third-party dealers, saying they would need approval to sell used Nintendo Games. Turns out the email was actually sent out in error, Amazon claims.

So, how do we manage? What do we do when consistently engaging in the difficult discussion about rape culture is hard on our hearts, but helpful for our students?

Chemistry major Sojung Kim and microbiology major Cuyler Luck will represent the Eberly College of Science as student marshals during Penn State’s virtual spring commencement ceremonies on Saturday, May 9.

The two-day event, now in its third year, offers workshops on mental health and burnout, time-management and goal-setting, and strategies for navigating toxic workplace environments.

The Hasselblad X1D II 50C turns heads with its stunning industrial design and medium format image sensor, but is hampered by an underpowered battery and sluggish response.

Finance ministers meeting in Brussels will try to push forward a legislative proposal for a levy on the European sales of companies with a global annual revenue of $853m or more, such as Facebook, Alphabet and Amazon.

Lipid II is an essential precursor of the bacterial cell wall biosynthesis and thereby an important target for various antibiotics. Several lanthionine-containing peptide antibiotics target lipid II with lanthionine-stabilized lipid II-binding motifs. Here, we used the biosynthesis system of the lantibiotic nisin to synthesize a two lipid II binding motifs-containing lantibiotic, termed TL19, which contains the N-terminal lipid II binding motif of nisin and the distinct C-terminal lipid II binding motif of one peptide of the two-component haloduracin (i.e. HalA1). Further characterization demonstrated that (i) TL19 exerts 64-fold stronger antimicrobial activity against E. faecium than nisin (1-22), which has only one lipid II binding site, and (ii) both the N- and C-terminal domains are essential for the potent antimicrobial activity of TL19, as evidenced by mutagenesis of each single and double domains. These results show the feasibility of a new approach to synthesize potent lantibiotics with two different lipid II binding motifs to treat specific antibiotic-resistant pathogens.

Objectives: Carbapenemase-producing Enterobacterales and specifically KPC-producing Klebsiella pneumoniae (KPC-Kp) are rapidly spreading worldwide. The prognosis of ventilator-associated pneumonia (VAP) caused by KPC-producing Klebsiella pneumoniae (KPC-Kp) is not well known. Our study tries to assess whether ventilator-associated pneumonia caused by a KPC-Kp strain is associated with higher all-cause mortality than if caused by carbapenem-susceptible isolates.

Study design and methods: This is a retrospective cohort study of patients with VAP due to K. pneumoniae from a 35-bed polyvalent Intensive Care Unit in a university hospital (> 40,000 annual admissions) between January 2012 and December 2016. Adjusted multivariate analysis was used to study the association of KPC-Kp with 30-day all-cause mortality (Cox regression).

Results. We analyze 69 cases of K. pneumoniae VAP of which 39 were produced by a KPC-Kp strain with high-level resistance to meropenem (MIC > 16 mg/mL). All-cause mortality at 30 days was 41% in the KPC-Kp group (16/39) and 33.3% in the carbapenem-susceptible cases (10/30). KPC-Kp etiology was not associated with higher mortality when controlled for confounders (adjusted hazard ratio [lsqb]HR[rsqb] 1.25; 95% CI: 0.46–3.41). Adequate targeted therapy (HR 0.03; 95% CI: <0.01–0.23) was associated with all-cause mortality.

Conclussion. Assuming the limitations due to the available sample size, the prognosis of VAP caused by KPC-Kp is similar to VAPs caused by carbapenem-susceptible K. pneumoniae when appropriate treatment is used.

The FBI seizes the internet domain to WeLeakInfo.com, a site that was cataloging billions of records, such as email addresses and passwords, from more than 10,300 data breaches at various companies and service providers.

"The entire energy market is still on a knife edge," says an economist.

Emilee Yaeger, an undergraduate student in the Science BS/MBA accelerated joint degree program, has been selected as the recipient of the 2019 Eberly College of Science Cooperative Education Student of the Year Award. The award recognizes the student’s academic achievements and contributions to the participating employer, the University, the community, and the field of cooperative education.

Penn State Health has appointed Don McKenna as president of Penn State Health Hampden Medical Center.

Beth E. Michalec, lecturer of corporate communication at Penn State Lehigh Valley, earned a doctorate in rhetoric from Duquesne University. Michalec was selected as a Fulbright specialist in June 2019 by the U.S. Department of State.

The onus is on you to uncover any defects before you buy, writes Angelique Ruzicka.

With credit card fraud rising at an alarming rate in the first quarter of the year, the Ombudsman for Banking Services has provided 10 tips to avoid becoming a victim of scammers.

Student Sandisiwe Msomi saved R23 400 in small change over a year, which she will now use to pay for the registration fees of her second academic year.

With the coronavirus pandemic pressing tens of thousands of the nation's school districts into extended closures, education administrators across the nation are wrestling with a complex and legalistic problem: how to keep services flowing for students with disabilities.

Quiz Yourself: What are today's biggest challenges to teacher recruitment?

The first in a three post series on challenges and opportunities with blended learning, starting with getting to actionable data.

Selected poems of Rachelle Bowser, Rachel Mennies, Erin Murphy and Eleanor Stanford have been chosen to represent the Pennsylvania Center for the Book’s 2020 Public Poetry Project, with poetry interpreted into art posters for the annual event.

Source: www.businessinsider.com - Friday, May 08, 2020
Los Angeles' food truck population of over 800 trucks faces a downturn in profits during the coronavirus pandemic, which threatens the livelihood of dozens of vendors. Trucks, many of which are family-owned, are losing up to 60% to 70% of their business. The disintegration of Los Angeles' food truck scene is creating ripple effects as truck owners, employees, and commissaries take financial hits. California recently allowed food trucks to obtain a permit to sell at rest stops, giving vendors the chance to sell to truckers outside the LA proper. Visit Business Insider's homepage for more stories . Los Angeles' food truck scene of over 800 operational trucks is facing a difficult time as business essentially grinds to a halt during the coronavirus pandemic. Food trucks, which are often run as small family businesses, cost on average $29,000 to run in LA, according to a report by the US Chambers of Commerce . But as the lifeblood of food trucks — foot traffic, social gathering, and events — disappears in the wake of the coronavirus, families and small businesses are suffering. "Food trucks rely on people to gather. That model went away pretty quickly," Ross Resnick, founder of food-truck-booking company Roaming Hunger, told the Orange County Register in March. "Pre-corona, it's events, it's workplaces, it's nighttime gatherings in markets. When you close your eyes and imagine a food truck, you imagine a group of people." There are

After recent confidence-eroding breaches, VPN providers are banding together to form a "trust initiative." This is the industry's much-needed chance to prove it's a safe guardian of customers' sensitive information, explains security expert Max Eddy.

JooYoung Seo, a doctoral candidate in the College of Education’s Learning, Design, and Technology program, has secured a highly competitive internship with RStudio that will allow him to help people just like himself — those with severe visual impairments.

Open resources, old textbooks, content controversies: How much do you know about what's happening in the world of curriculum and instruction?

To view more press releases, please visit http://ir.wintrust.com/news.aspx?iid=1024452.

This week’s episode of #EntrepreneurCorner features Antoinette Prophy, who talks about starting her own business at the age of 26, and the benefits of surrounding yourself with smart employees.

Massive distribution efforts by OM teams in Bangladesh over more than 10 years sowed gospel seeds and made the Bengali New Testament a #1 best seller.

The portfolio comprises three properties in the capital Bucharest, and one in Timisoara, a city in the west of the country.

With Penn State Scranton students now into their sixth week of stay-at-home restrictions due to the COVID-19 pandemic, Campus Counselor Katherine Stefanelli offers some tips on how to deal with the stress, anxiety and loneliness that some may be feeling.

Amsterdam and Groningen will stage the expanded 16-team finals from 19 January to 6 February 2022.

The four finalists for National Teacher of the Year say their fellow teachers are sharing their stories and their students' stories more than ever, and it's time for policymakers to listen.

Two former semi-finalists have been paired together in the round of 16 as Eintracht Frankfurt go head to head for the first time with Basel.

Basel have one foot in the quarter-finals after overwhelming 2018/19 semi-finalists Eintracht Frankfurt 3-0 away in the first leg of their round of 16 tie.

Schools can't even afford to hire enough teachers, so why are we surprised that teachers are turning to a website for resources? asks Kat Tipton.

25-state coalition files briefs in Bankruptcy Court Attorney General Kathy Jennings, along with a bipartisan group of 24 attorneys general, filed today two briefs opposing a request by Purdue Pharma to stop all lawsuits against the company and the Sackler family. “The Sacklers extracted up to $13 billion from Purdue while drugs like OxyContin wreaked […]

Secretary of State Jeffrey Bullock has suspended the Delaware chemical dependency counseling license of Sachin Karnik in light of recent criminal charges filed against him.