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A new polymer lab-on-a-chip (LOC) based on a microfluidic capillary flow assay (MCFA) for detecting unbound cortisol in saliva

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00071J, Paper
Vinitha T. U., Sthitodhi Ghosh, Alexander Milleman, Thinh Nguyen, Chong H. Ahn
A new polymer lab-on-a-chip with on-chip dried reagents for microfluidic capillary flow assay (MCFA) detection of unbound cortisol in saliva.
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Photonic crystal-based smart contact lens for continuous intraocular pressure monitoring

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01268K, Paper
Bohee Maeng, Hyung-kwan Chang, Jungyul Park
A powerless smart contact lens enabling to monitor intraocular pressure (IOP) by checking the visual color change in photonic crystal structure with a microhydraulic amplification system has been realized.
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Multiplexed homogeneous digital immunoassay based on single-particle motion analysis

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper
Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
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Quantitatively controllable fluid flows with ballpoint-pen-printed patterns for programmable photo-paper-based microfluidic devices

Lab Chip, 2020, 20,1601-1611
DOI: 10.1039/D0LC00115E, Paper
Veasna Soum, Sooyong Park, Albertus Ivan Brilian, Jae-Youl Choi, Yongwoo Lee, Wonjung Kim, Oh-Sun Kwon, Kwanwoo Shin
A precise, simple, and inexpensive method for controlling fluid flow in a photo-paper-based microfluidic device was reported.
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High-sensitivity microliter blood pressure sensors based on patterned micro-nanostructure arrays

Lab Chip, 2020, 20,1554-1561
DOI: 10.1039/D0LC00063A, Communication
Nianzuo Yu, Yongshun Liu, Bai Ji, Shuli Wang, Yunyun Chen, Tianmeng Sun, Junhu Zhang, Bai Yang
Blood pressure sensors are proposed to measure the value of central venous pressure, and diagnose the severity of hypertension, hypotension and arterial thrombosis.
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Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Lab Chip, 2020, 20,1621-1627
DOI: 10.1039/D0LC00304B, Paper
Fu Sun, Anurup Ganguli, Judy Nguyen, Ryan Brisbin, Krithika Shanmugam, David L. Hirschberg, Matthew B. Wheeler, Rashid Bashir, David M. Nash, Brian T. Cunningham
A 30-minute nucleic acid test for equine respiratory virus from nasal swab material, detected with a smartphone.
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A Web-based Automated Machine Learning Platform to Analyze Liquid Biopsy Data

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00096E, Paper
Hanfei Shen, Tony Liu, Jesse Cui, Piyush Borole, Ari Benjamin, Konrad Kording, David Issadore
Liquid biopsy (LB) technologies continue to improve in sensitivity, specificity, and multiplexing and can measure an ever growing library of disease biomarkers. However, clinical interpretation of the increasingly large sets...
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[ASAP] Combining Docking Pose Rank and Structure with Deep Learning Improves Protein–Ligand Binding Mode Prediction over a Baseline Docking Approach

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00927




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[ASAP] Correction of Missing-Wedge Artifacts in Filamentous Tomograms by Template-Based Constrained Deconvolution

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01111




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[ASAP] Development and Evaluation of MM/GBSA Based on a Variable Dielectric GB Model for Predicting Protein–Ligand Binding Affinities

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00024




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[ASAP] Simulation-Based Methods for Model Building and Refinement in Cryoelectron Microscopy

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00087




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[ASAP] Cov_FB3D: A De Novo Covalent Drug Design Protocol Integrating the BA-SAMP Strategy and Machine-Learning-Based Synthetic Tractability Evaluation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01197




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[ASAP] Structure- and Ligand-Based Virtual Screening on DUD-E<sup>+</sup>: Performance Dependence on Approximations to the Binding Pocket

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00115




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[ASAP] Mechanism-Based Rational Discovery and <italic toggle="yes">In Vitro</italic> Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01133




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[ASAP] Evaluating Scalable Uncertainty Estimation Methods for Deep Learning-Based Molecular Property Prediction

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00975




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[ASAP] Prototype Selection Method Based on the Rivality and Reliability Indexes for the Improvement of the Classification Models and External Predictions

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00176




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[ASAP] Scope of 3D Shape-Based Approaches in Predicting the Macromolecular Targets of Structurally Complex Small Molecules Including Natural Products and Macrocyclic Ligands

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00161




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Faith-based organizations in development discourses and practice / edited by Andreas Heuser and Jens Koehrsen

Online Resource




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Legal Research Reports: Points-Based and Family Immigration

The Law Library of Congress is proud to present the report, Points-Based and Family Immigration.

This report explains the points-based immigration systems adopted by Australia, Austria, Canada, Japan, New Zealand, South Korea, and the United Kingdom. Each of these countries determines a noncitizen’s eligibility to obtain a particular visa or residence status partly by whether that noncitizen is able to score above a threshold number of points in accordance with the country’s points scoring system. All of the countries have points-based immigration system for skilled workers. Other categories for which a points-based immigration system is used include investor, entrepreneur/business start-up, persons with exceptional capabilities, temporary worker, and job seeker.  

This report is one of many prepared by the Law Library of Congress. Visit the Comprehensive Index of Legal Reports page for a complete listing of reports and the Current Legal Topics page for our highlighted and newer reports. 




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The biological bases of economic behaviour: a concise introduction / David McFarland

Hayden Library - QL785.M455 2016




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Baseline Ventures signs India’s under-19 cricket captain Priyam Garg

The multi-year deal will see Baseline managing all the commercial interests of Garg. Born in Meerut, UP, Garg made his first-class debut against Goa in 2018 where he went on to score an unbeaten 117. He recently led the Under-19 Indian team at the World Cup in South Africa where they finished runners-up.




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Antibody-based eye drop may treat dry eye disease: Study

Dry eye disease is caused by abnormalities in the tear fluid and results in dry areas over the cornea, the transparent outer layer of the eye, which can lead to disabling eye pain and sensitivity to light in severe cases




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'Can confirm COVID-19 in 2 hours at low cost': Harsh Vardhan announces new test kit developed by Kerala-based institute

The detection time is 10 minutes, and the sample to result in time will be less than 2 hours, Harsh Vardhan said.




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Policing UK Honour-Based Abuse Crime [electronic resource] / by Rachael Aplin

Aplin, Rachael, author




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Studies of the labile lead pool using a rhodamine-based fluorescent probe

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00056F, Communication
Jianping Zhu, Jia Hao Yeo, Amy A. Bowyer, Nicholas Proschogo, Elizabeth J. New
A rhodamine-based fluorescent lead probe reports on the labile lead pool within cells.
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Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00084A, Paper
Sabiha Parveen, J. A. Cowan, Zhen Yu, Farukh Arjmand
Copper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ruthenium(III) complexes containing thiazole-based ligands that modulate amyloid-β aggregation

Metallomics, 2020, 12,491-503
DOI: 10.1039/D0MT00054J, Paper
Samantha E. Huffman, Gideon K. Yawson, Samuel S. Fisher, Paige J. Bothwell, David C. Platt, Marjorie A. Jones, Christopher G. Hamaker, Michael I. Webb
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Illustrated topical dictionary of the Western Desert language : based on the Ngaanyatjarra dialect / W.H. Douglas

Douglas, Wilfrid H. (Wilfrid Henry)




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Chuang xin xing ren cai ji li ji zhi yan jiu : ji yu xin li qi yue de shi jiao = Study on incentive mechanism of innovative talent based on psychological contract perspective / Zhu Xiaomei zhu

Zhu, Xiaomei




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[ASAP] Positive Effects of H<sub>2</sub>O on the Hydrogen Oxidation Reaction on Sr<sub>2</sub>Fe<sub>1.5</sub>Mo<sub>0.5</sub>O<sub>6-d</sub>-Based Perovskite Anodes for Solid Oxide Fuel Cells

ACS Catalysis
DOI: 10.1021/acscatal.9b05458




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[ASAP] A Thiadiazole-Based Covalent Organic Framework: A Metal-Free Electrocatalyst toward Oxygen Evolution Reaction

ACS Catalysis
DOI: 10.1021/acscatal.9b05470




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[ASAP] Development of Ketone-Based Brominating Agents (KBA) for the Practical Asymmetric a-Bromination of Aldehydes Catalyzed by Tritylpyrrolidine

ACS Catalysis
DOI: 10.1021/acscatal.0c01596




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UK-based Triumph Motorcycles eyes 15% market share in Indian superbike category

The company, which entered Indian market last year with 10 models, expanded its product range to 12 models with the launch of Thunderbird LT.




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Science Podcast - Canine origins, asexual bacterial adaptation, perovskite-based solar cells, and more (15 Nov 2013)

The origin of dog domestication in Europe with Robert Wayne; Richard Lenski tracks the adaptation of bacteria over 50,000 generations; Robert Services describes the prospects of a new contender in solar technology.




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Artificial intelligence programs that learn concepts based on just a few examples and a daily news roundup

Brenden Lake discusses a new computational model that rivals the human ability to learn new concepts based on just a single example; David Grimm talks about attracting cockroaches, searching for habitable planets, and looking to street dogs to learn about domestication. Hosted by Susanne Bard. [Img: Rodrigo Basaure CC BY 2.0, via flickr]




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Podcast: Battling it out in the Bronze Age, letting go of orcas, and evolving silicon-based life

Online News Editor David Grimm shares stories on SeaWorld’s plans for killer whales, the first steps toward silicon-based life, and the ripple effect of old dads on multiple generations.   Andrew Curry joins host Sarah Crespi to discuss a grisly find in Northern Germany that suggests Bronze Age northern Europe was more organized and more violent than thought.   [Image: ANDESAMT FÜR KULTUR UND DENKMALPFLEGE MECKLENBURG-VORPOMMERN/LANDESARCHÄOLOGIE/S. SUHR ]




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Podcast: Saving grizzlies from trains, cheap sun-powered water purification, and a deep look at science-based policymaking

This week, we chat about why grizzly bears seem to be dying on Canadian railway tracks, slow-release fertilizers that reduce environmental damage, and cleaning water with the power of the sun on the cheap, with Online News Editor David Grimm. And David Malakoff joins Alexa Billow to discuss a package of stories on the role of science and evidence in policymaking[link TK]. Listen to previous podcasts.  [Image: tacky_ch/iStockphoto; Music: Jeffrey Cook]




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The biology of color, a database of industrial espionage, and a link between prions and diabetes

This week we hear stories on diagnosing Alzheimer’s disease in chimps, a potential new pathway to diabetes—through prions—and what a database of industrial espionage says about the economics of spying with Online News Editors David Grimm and Catherine Matacic. Sarah Crespi talks to Innes Cuthill about how the biology of color intersects with behavior, development, and vision. And Mary Soon Lee joins to share some of her chemistry haiku—one poem for each element in the periodic table. Listen to previous podcasts. [Image: Zoltan Tasi/Unsplash; Music: Jeffrey Cook]




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Exploding the Cambrian and building a DNA database for forensics

First, we hear from science writer Joshua Sokol about his trip to the Cambrian—well not quite. He talks with host Megan Cantwell about his travels to a remote site in the mountains of British Columbia where some of Earth’s first animals—including a mysterious, alien-looking creature—are spilling out of Canadian rocks.   Also on this week’s show, host Sarah Crespi talks with James Hazel a postdoctoral research fellow at the Center for Genetic Privacy and Identity in Community Settings at Vanderbilt University in Nashville about a proposal for creating a universal forensic DNA database. He and his co-authors argue that current, invasive practices such as law enforcement subpoenaing medical records, commercial genetic profiles, and other sets of extremely detailed genetic information during criminal investigations, would be curtailed if a forensics-use-only universal database were created.     This week’s episode was edited by Podigy.   Read a transcript (PDF) Listen to previous podcasts.   About the Science Podcast  




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Biobased Polyols for Industrial Polymers


 
The replacement of polyols synthesized from petrochemical by polyols originating from natural products, notably from vegetable oils and animal fats, has been the subject of research projects for a number of decades.

Very recently, however, the polymers industry has intensified its efforts to include the “green products”, such as biobased polyols, in applications already available in the market. Examples of such applications include polyurethane foams


Read More...




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NMR-based plasma metabonomics in hyperlipidemia mice

Anal. Methods, 2020, 12,1995-2001
DOI: 10.1039/D0AY00487A, Paper
Yun Li, Xiu-ju Zhao
Hyperlipidemia dynamics need to be elucidated.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Molecular analysis of edible bird’s nest and rapid authentication of Aerodramus fuciphagus from its subspecies by PCR-RFLP based on the cytb gene

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/C9AY02548K, Paper
Kunfeng Liu, Maoyong Wu, Xuemei Lin, Piyanuch Lonan, Sitai Chen, Yina Wu, Xiaoping Lai, Liangwen Yu, Xiaoming Zhou, Geng Li
Edible bird's nest (EBN), for its great nutritional value, is widely used around the world, especially in China and Singapore. EBNs of different origins and types may vary in price...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A dual-functional PDMS-assisted paper-based SERS platform for reliable detection of thiram residue both on fruit surface and in juice

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00483A, Paper
Shuang Lin, Wuliji Hasi, Siqingaowa Han, Xiang Lin, Li Wang
In this work, a dual-functional SERS platform was developed via a paper-based SERS substrate with the aid of hydrophobic Polydimethylsiloxane (PDMS) for effective and reliable measurements of thiram on fruit...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A novel microfluidic paper-based analytical device based on chemiluminescence for the determination of β-agonists in swine hair

Anal. Methods, 2020, Advance Article
DOI: 10.1039/C9AY02754H, Paper
Wei Li, Yong Luo, Xiqing Yue, Junrui Wu, Rina Wu, Yu Qiao, Qing Peng, Bo Shi, Bingcheng Lin, Xu Chen
β-Agonists are illegal feed additives in the feed industries of many countries, especially China.
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Development of a magnetic dispersive micro-solid-phase extraction method based on a deep eutectic solvent as a carrier for the rapid determination of meloxicam in biological samples

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00095G, Paper
Samira Rastbood, Mohammad Reza Hadjmohammadi, Seyedeh Maedeh Majidi
An environmentally friendly magnetic dispersive micro solid phase extraction based on a deep eutectic solvent as a carrier and disperser of adsorbents.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Shenling Baizhu San improves functional dyspepsia in rats as revealed by 1H-NMR based metabolomics

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00580K, Paper
Shaobao Zhang, Zengmei Xu, Xueqing Cao, Yuzhen Xie, Lei Lin, Xiao Zhang, Baorong Zou, Deliang Liu, Ying Cai, Qiongfeng Liao, Zhiyong Xie
Functional dyspepsia (FD), a common gastrointestinal disorder around the world, is driven by multiple factors, making prevention and treatment a major challenge.
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Ultrasensitive immunochromatographic strips for fast screening of the nicarbazin marker in chicken breast and liver samples based on monoclonal antibodies

Anal. Methods, 2020, 12,2143-2151
DOI: 10.1039/D0AY00414F, Paper
Xiaoxin Xu, Liqiang Liu, Xiaoling Wu, Hua Kuang, Chuanlai Xu
Nicarbazin is an anticoccidial drug with a residue limit in animal husbandry.
The content of this RSS Feed (c) The Royal Society of Chemistry




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High cytotoxic activity of ZnO@leucovorin nanocomposite based materials against an MCF-7 cell model

Anal. Methods, 2020, 12,2176-2184
DOI: 10.1039/D0AY00498G, Paper
Mohamed Fathi Sanad, Esraa Samy Abu Serea, Shereen Magdy Bazid, Shimaa Nabih, Md Ariful Ahsan, Ahmed Esmail Shalan
In the current work, we design a multifunctional hybrid nanocomposite for treating MCF-7 cell lines, which act as a model for breast cancer cells, to overcome the serious side-effects of chemotherapy treatment pathways.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discrimination between fresh, chilled, and frozen/thawed chicken based on its skin's spectrochemical and optical properties

Anal. Methods, 2020, 12,2093-2101
DOI: 10.1039/D0AY00324G, Paper
Omnia Hamdy, Zienab Abdel-Salam, Mohamed Abdel-Harith
Monitoring of the spectrochemical and optical properties of biomaterials has been widely utilized in many biomedical applications for both diagnosis and therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Aptamer-based fluorometric determination of chloramphenicol by controlling the activity of hemin as a peroxidase mimetic

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00389A, Paper
Ling-Chen Wang, Cheng-Yi Hong, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang
A method for the aptamer-based determination of chloramphenicol (CAP) was developed by exploiting the peroxidase mimicking activity of hemin.
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The content of this RSS Feed (c) The Royal Society of Chemistry