Finding antivirals to reduce coronavirus disease 2019 (COVID-19) morbidity and mortality has been challenging. Large randomized clinical trials that aimed to test four repurposed drugs, hydroxychloroquine, lopinavir-ritonavir, interferon beta 1a, and remdesivir, have shown that these compounds lack an impact on the COVID-19 course. Although the phase III COVID-19 vaccine trial results are encouraging, the search for effective COVID-19 therapeutics should not stop. Recently, plitidepsin (aplidin) demonstrated highly effective preclinical activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its antiviral activity was 27.5-fold more potent than that of remdesivir (K. M. White, R. Rosales, S. Yildiz, T. Kehrer, et al., Science, 2021, https://science.sciencemag.org/content/early/2021/01/22/science.abf4058). Plitidepsin, a repurposed drug developed for the treatment of multiple myeloma, targets the host translation cofactor eEF1A. Plitidepsin has shown efficacy in animal models and phase I/II human trials. Although plitidepsin is administered intravenously and its toxicity profile remains to be fully characterized, this compound may be a promising alternative COVID-19 therapeutic.

Discovery Health Medical Scheme's (DHMS) 2023 cancer claims payouts were almost 19% higher than the previous year though the scheme says screening rates in South Africa have mostly returned to pre-pandemic levels.

DOVER – Revenue from a new opioid impact fee created by the Delaware General Assembly in 2019 will be used to prevent overdose deaths and provide new services to those seeking treatment for their substance use disorder, the Delaware Department of Health and Social Services (DHSS) and Sen. Stephanie Hansen announced Wednesday. DHSS Secretary Molly […]

DOVER, DE (April 14, 2022) – Today, the Delaware Division of Public Health (DPH) is announcing the launch of the COVID-19 Test-to-Treat program in Delaware as part of a federal initiative aimed at providing convenient testing and treatment options combined in one location. Test-to-treat locations are designed to be a “one-stop shop” for individuals seeking diagnosis and […]

DOVER, Del. (March 17, 2023) -  The Delaware Division of Public Health (DPH) saw a decrease in case rates and hospitalizations from COVID-19 over the past month and urges residents to remain vigilant and use the tools proven successful in the fight against the virus to continue these trends. While rates are down from the […]

Halloween is hauntingly around the corner. While it is known for its fun, costumes and candy, Halloween can also be a little scary for parents and pet owners – but it doesn’t have to be! The Delaware Division of Public Health (DPH) offers health and safety tips for a safe and fun celebration this Halloween. “Creep” It Healthy with These Treats Halloween can be a fun and exciting holiday […]

On April 9, 150 Delaware Cancer Consortium (DCC) members gathered for their 2024 retreat for presentations by prominent local and national speakers, including four cancer survivors who shared their diagnosis, care, and experience living with cancer. The theme was Vision. Purpose. Action. Coming Together to Eliminate Cancer Disparities, aligning with DCC’s goal to implement culturally inclusive initiatives […]

Halloween is one of my favorite times of the year – I'm a Halloween enthusiast. It’s a time for spine-tingling thrills, haunted tales and lots of candy corn. But there’s one fear lurking in the shadows that sends shivers down the spines of data scientists, IT leaders and executives alike, [...]

Tricks, treats and tech: Don't let your data scare you was published on SAS Voices by Udo Sglavo

DNREC will begin the annual treatment of downstate public ponds – Wagamons Pond in Milton and Concord Pond near Seaford – for the foreign invasive aquatic weed hydrilla on Thursday, June 13, weather permitting. Hydrilla is a non-native plant that likely entered the state through the aquarium trade. Uncontrolled hydrilla can choke ponds and other waterways, crowding out beneficial plant species and preventing fishing and boating access.

Ukraine abandoned its constitutional neutrality to pursue EU and NATO membership only in 2019, years after Russia annexed Crimea and backed pro-Russia separatists in Donbas. NATO considered Ukraine’s membership after Moscow invaded Georgia, starting a war in Europe.

Man accused of stealing car and taking money from a shrine placed under two-year treatment order by a court

Remarks by Masatsugu Asakawa, President, Asian Development Bank, at the 8th Greater Mekong Subregion Summit, Leaders’ Retreat, 7 November 2024

Male pattern baldness could soon be a thing of the past, with new hair loss treatments beginning to show tantalising results

We're finally pinning down the mechanisms that drive obsessive-compulsive disorder, revealing a complex combination of imbalanced brain networks, the immune system and even gut microbes

Snoring is often viewed as harmless, at least to the snorer, but we are now uncovering its potentially serious effects on cardiovascular health. And finding ways to stop is surprisingly challenging

Cut marks on a 4000-year-old skull suggest ancient Egyptian doctors tried to treat a man with nasopharyngeal cancer

Title: Breast Cancer Treatment Effects on Sex Life a Hidden Burden
Category: Health News
Created: 8/8/2022 12:00:00 AM
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Title: How Is PIK3CA Mutation Treated?
Category: Diseases and Conditions
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Title: What Is the Treatment for Asthmatic Bronchitis?
Category: Diseases and Conditions
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Title: Why Treatment Helps Some Asthma Patients More Than Others
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Title: Parkinson's: Treatment for Symptoms
Category: Health News
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Title: Brain 'Pacemaker' Treats Parkinson's
Category: Health News
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Title: Early COPD Treatment Slows Disease
Category: Health News
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Category: Health News
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Category: Health News
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Category: Health News
Created: 8/28/2013 9:35:00 AM
Last Editorial Review: 8/28/2013 12:00:00 AM

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Category: Health News
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Last Editorial Review: 8/28/2013 12:00:00 AM

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Category: Health News
Created: 8/23/2014 11:00:00 AM
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Category: Health News
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Last Editorial Review: 8/28/2014 12:00:00 AM

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Category: Health News
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Created: 8/26/2016 12:00:00 AM
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Category: Health News
Created: 8/25/2017 12:00:00 AM
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Category: Health News
Created: 8/29/2017 12:00:00 AM
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Created: 8/30/2017 12:00:00 AM
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Category: Health News
Created: 9/1/2017 12:00:00 AM
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Created: 8/27/2018 12:00:00 AM
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Title: Ancient Treatment May Help Fight 'Superbugs'
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Created: 8/29/2018 12:00:00 AM
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Category: Health News
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Title: Justice Ruth Bader Ginsburg Treated for Pancreatic Cancer
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Title: What Treatments Work Best to Prevent Suicide?
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Created: 8/27/2019 12:00:00 AM
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Title: Nourianz Approved to Treat 'Off' Episodes in Parkinson Disease
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Title: Health Tip: Treating a Jammed Finger
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Title: Brutus & Barnaby Pig Ear Treats For Dogs Recalled
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Title: FDA Approves Wider Use of Plasma as Coronavirus Treatment
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: Survivors' Plasma Still a Solid Option for Treating COVID-19, Experts Say
Category: Health News
Created: 8/26/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM

Title: Stop Using Ivermectin Veterinary Drug to Treat COVID, FDA Urges
Category: Health News
Created: 8/23/2021 12:00:00 AM
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Title: 'Stepped' Approach to Treating Diabetic Eye Disease May Be Best
Category: Health News
Created: 7/15/2022 12:00:00 AM
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