The policy forum officially launches the conceptual framework to the public and offers an opportunity for participants to discuss the key issues for emerging Asia: housing, buildings and energy, land use and transport, water and waste management, green goods and services.

Action to prevent the risk of major flooding in Paris and the Ile de France region has improved in recent years – particularly after the Seine burst its banks in May and June 2016 – but urban and territorial planning needs to be better adapted, governance strengthened and long-term funding clarified, according to the OECD.

The conference will cover developments and the state-of-the art of environmental microbiology, as it is applied for biotechnological purposes, and the role of genetic engineering of micro-organisms intended for use in the environment, now and in the near future.

After weeks of lockdown, starting again will bring its own challenges for small retailers

Cecile Rol Tanguy (pictured) died yesterday at her home in Monteaux, central France, as Europe commemorated the 75th anniversary of the surrender of Nazi Germany to Allied forces.

1. Leave granted.

2. This appeal emanates from the judgment and order dated 29.8.2016 passed by the High Court of Judicature at Bombay 1 in Second Appeal No. 771/2015, whereby the judgment and decree dated 11.2.2015 passed by the District Judge, Ratnagiri 2 in Regular Civil Appeal No. 34/2011 came to be affirmed, as a result of which the suit filed by the respondent Nos. 1 to 19 (original plaintiffs) in the Court of Civil Judge, Senior Division, Signature Not Verified Digitally signed by DEEPAK SINGH Date: 2020.05.06 16:03:13 IST Reason:

1 For short, “the High Court” 2 For short, “the first appellate Court” 2 Ratnagiri3 being RCS No. 25/2005 for permanent injunction against the appellant and respondent No. 20 (State of Maharashtra), restraining them from starting the Solid Waste Disposal Project4 at the suit property, has been decreed. In other words, the trial Court had dismissed the suit, but the first appellate Court allowed (decreed) the same, which decision has been upheld by the High Court in the Second Appeal.

Sterling has enjoyed a blistering start to the season, scoring eight goals in seven games for Manchester City and England, earning him comparisions with some of the game's greats.

John Ibrahim reckons a copy of Lesbian Sex Secrets For Men that Paris Hilton sent him after he missed out on a threesome with the model was seized by police to embarrass him.

Crystal Palace chairman Steve Parish has posted a tongue-in-cheek comment about how the Premier League season should be decided. The Premier League confirmed all games will be suspended.

The Palace chairman has said employees who are affected by coronavirus will still receive full pay, while insisting matchday staff who have lost work due to the league's suspension will not be out of pocket.

The 21-year-old right-back joined the club from Porto in 2018 for around £18m.but he has had few opportunities this season due to sensational form of Aaron Wan-Bissaka.

Steve Parish has defended attempts to get the season back up and running amid the coronavirus pandemic, stressing not doing so would be a major financial blow to taxpayers and the football community.

Premier League clubs could be hit with a financial crisis similar to those faced by airlines across the world if football doesn't return by August, Crystal Palace chief Steve Parish has claimed.

The Hyundai Grand i10 NIOS BS6 petrol variant mileage figures have been revealed. The company had updated the petrol engine to achieve BS6 compliance earlier this year, and also added a new turbo-engine to the Grand i10 NIOS BS6.

Archives, Room Use Only - TK5.I68 1900

Six different rare-earth oxyapatites, including Ca2RE8(SiO4)6O2 (RE = La, Nd, Sm, Eu, or Yb) and NaLa9(SiO4)6O2, were synthesized using solution-based processes followed by cold pressing and sinter­ing. The crystal structures of the synthesized oxyapatites were determined from powder X-ray diffraction (P-XRD) and their chemistries verified with electron probe microanalysis (EPMA). All the oxyapatites were isostructural within the hexa­gonal space group P63/m and showed similar unit-cell parameters. The isolated [SiO4]4− tetra­hedra in each crystal are linked by the cations at the 4f and 6h sites occupied by RE3+ and Ca2+ in Ca2RE8(SiO4)6O2 or La3+ and Na+ in NaLa9(SiO4)6O2. The lattice parameters, cell volumes, and densities of the synthesized oxyapatites fit well to the trendlines calculated from literature values.

The title hydrated mol­ecular salt (systematic name: tetra-n-butyl­ammonium 2,6-dioxo-1,2,3,6-tetra­hydro­pyrimidine-4-carboxyl­ate monohydrate), C16H36N+·C5H3N2O4−·H2O, crystallizes with N—H⋯O and O—H⋯O hydrogen-bonded double-stranded anti­parallel ribbons consisting of the hydro­philic orotate monoanions and water mol­ecules, separated by the bulky hydro­phobic cations. The hydro­phobic and hydro­philic regions of the structure are joined by weaker non-classical C—H⋯O hydrogen bonds. An accurate structure analysis conducted at T = 100 K is compared to a lower-resolution less accurate determination using data measured at T = 295 K. The results of both analyses are evaluated using a knowledge-based approach, and it is found that the less accurate room-temperature structure analysis provides geometric data that are similar to those derived from the accurate low-temperature analysis, with both sets of results consistent with previously analyzed structures. A minor disorder of one methyl group in the cation at low temperature was found to be slightly more complex at room temperature; while still involving a minor fraction of the structure, the disorder at room temperature was found to require a non-routine treatment, which is described in detail.

Three huntite-type aluminoborates of stoichiometry REAl3(BO3)4 (RE = Tb, Dy and Ho), namely, terbium/dysprosium/holmium trialuminium tetrakis(borate), were synthesized by slow cooling within a K2Mo3O10 flux with spontaneous crystallization. The crystal structures were determined using single-crystal X-ray diffraction (SC-XRD) data. The synthesized borates are isostructural to the huntite [CaMg3(CO3)4] structure and crystallized within the trigonal R32 space group. The structural parameters were compared to literature data of other huntite REAl3(BO3)4 crystals within the R32 space group. All three borates fit well into the trends calculated from the literature data. The unit-cell parameters and volumes increase linearly with larger RE cations whereas the densities decrease. All of the crystals studied were refined as inversion twins.

This article describes new developments in the CrystalCMP software. In particular, an automatic procedure for comparison of molecular packing is presented. The key components are an automated procedure for fragment selection and the replacement of the angle calculation by root-mean-square deviation of atomic positions. The procedure was tested on a large data set taken from the Cambridge Structural Database (CSD) and the results of all the comparisons were saved as an HTML page, which is freely available on the web. The analysis of the results allowed estimation of the threshold for identification of identical packing and allowed duplicates and entries with potentially incorrect space groups to be found in the CSD.

In this work, two methods of high-resolution X-ray data refinement: multipole refinement (MM) and Hirshfeld atom refinement (HAR) – together with X-ray wavefunction refinement (XWR) – are applied to investigate the refinement of positions and anisotropic thermal motion of hydrogen atoms, experiment-based reconstruction of electron density, refinement of anharmonic thermal vibrations, as well as the effects of excluding the weakest reflections in the refinement. The study is based on X-ray data sets of varying quality collected for the crystals of four quinoline derivatives with Cl, Br, I atoms and the -S-Ph group as substituents. Energetic investigations are performed, comprising the calculation of the energy of intermolecular interactions, cohesive and geometrical relaxation energy. The results obtained for experimentally derived structures are verified against the values calculated for structures optimized using dispersion-corrected periodic density functional theory. For the high-quality data sets (the Cl and -S-Ph compounds), both MM and XWR could be successfully used to refine the atomic displacement parameters and the positions of hydrogen atoms; however, the bond lengths obtained with XWR were more precise and closer to the theoretical values. In the application to the more challenging data sets (the Br and I compounds), only XWR enabled free refinement of hydrogen atom geometrical parameters, nevertheless, the results clearly showed poor data quality. For both refinement methods, the energy values (intermolecular interactions, cohesive and relaxation) calculated for the experimental structures were in similar agreement with the values associated with the optimized structures – the most significant divergences were observed when experimental geometries were biased by poor data quality. XWR was found to be more robust in avoiding incorrect distortions of the reconstructed electron density as a result of data quality issues. Based on the problem of anharmonic thermal motion refinement, this study reveals that for the most correct interpretation of the obtained results, it is necessary to use the complete data set, including the weak reflections in order to draw conclusions.

Human carbonic anhydrase IX (CA IX) expression is upregulated in hypoxic solid tumours, promoting cell survival and metastasis. This observation has made CA IX a target for the development of CA isoform-selective inhibitors. To enable structural studies of CA IX–inhibitor complexes using X-ray and neutron crystallography, a CA IX surface variant (CA IXSV; the catalytic domain with six surface amino-acid substitutions) has been developed that can be routinely crystallized. Here, the preparation of protiated (H/H), H/D-exchanged (H/D) and deuterated (D/D) CA IXSV for crystallographic studies and their structural comparison are described. Four CA IXSV X-ray crystal structures are compared: two H/H crystal forms, an H/D crystal form and a D/D crystal form. The overall active-site organization in each version is essentially the same, with only minor positional changes in active-site solvent, which may be owing to deuteration and/or resolution differences. Analysis of the crystal unit-cell packing reveals different crystallographic and noncrystallographic dimers of CA IXSV compared with previous reports. To our knowledge, this is the first report comparing three different deuterium-labelled crystal structures of the same protein, marking an important step in validating the active-site structure of CA IXSV for neutron protein crystallography.

Cryocooling for macromolecular crystallography is usually performed via plunging the crystal into a liquid cryogen or placing the crystal in a cold gas stream. These two approaches are compared here for the case of nitro­gen cooling. The results show that gas stream cooling, which typically cools the crystal more slowly, yields lower mosaicity and, in some cases, a stronger anomalous signal relative to rapid plunge cooling. During plunging, moving the crystal slowly through the cold gas layer above the liquid surface can produce mosaicity similar to gas stream cooling. Annealing plunge cooled crystals by warming and recooling in the gas stream allows the mosaicity and anomalous signal to recover. For tetragonal thermolysin, the observed effects are less pronounced when the cryosolvent has smaller thermal contraction, under which conditions the protein structures from plunge cooled and gas stream cooled crystals are very similar. Finally, this work also demonstrates that the resolution dependence of the reflecting range is correlated with the cooling method, suggesting it may be a useful tool for discerning whether crystals are cooled too rapidly. The results support previous studies suggesting that slower cooling methods are less deleterious to crystal order, as long as ice formation is prevented and dehydration is limited.

The sin2ψ and cosα methods are compared via diffracting-grain identification from electron backscatter diffraction maps. Artificial textures created by the X-ray diffraction measurements are plotted and X-ray elastic constants of the diffracting-grain sets are computed.

New developments in the program CrystalCMP are presented, and the program is tested on a large number of crystal structures extracted from the Cambridge Structural Database.

The addition of tert-butyl hydro­peroxide (tBuOOH) to two MnII complexes, differing by a small synthetic alteration from an ethyl to a propyl linker in the ligand scaffold, results in the formation of the high-valent bis-oxo complexes, {[MnIV{N4(6-Me-DPEN)}]2(μ-O)2}2+ (1) and {[MnIV{N4(6-Me-DPPN)}]2(μ-O)2}2+ (2).

Features of azimuthal plots for RHEED and its new counterpart, RHEPD, are discussed. The plots, for both electrons and positrons, are determined using dynamical diffraction theory.

Cancer-causing chemicals that occur naturally in foods are far more numerous in the human diet than synthetic carcinogens, yet both types are consumed at levels so low that they currently appear to pose little threat to human health, a committee of the National Research Council said in a report released today.

Two shared electric car schemes, in Berlin and Paris, have been examined by a recent study. Although both schemes are progressive, Berlin's takes an 'inter-modal' approach to encouraging sustainable mobility, because it integrates electric cars into the wider public transport system. The scheme in Paris, however, focuses on cars as the main form of transport.

Researchers have developed an online tool to help water managers find effective ways of tackling eutrophication, an excess growth of weeds and algae that suffocates life in rivers, lakes and seas. They describe the tool as quick and easy to use and understand. Users can compare the likely effects of different strategies for cutting nutrient pollution in surface waters via an interactive map-based system; this is currently available for Sweden and Europe as a whole.

Ahead of the 2016 Paris Agreement on climate change, various climate and energy policy actions were proposed to target pledged 'nationally determined contributions' (NDCs). Now, researchers have quantified the global impact of implementing these actions on air quality, and determined that they have the potential to substantially reduce air pollution worldwide, with significant co-benefits for human health and agriculture — including the prevention of up to 99 000 premature deaths annually by 2030. These co-benefits could offset the global costs of climate policy; this study thus calls for an integrated policy perspective that aims to maximise the benefits of NDCs for climate and health.

An Olympic bid is as good a reason as any for the Parisian architectural landmark to get all gussied up.

The U.N. summit is going on despite recent terrorist attacks, and it does so with diplomatic momentum as well as a renewed sense of global solidarity.

The new U.N. climate agreement is being called 'a monumental triumph' and 'a turning point for the world.' Here are a few key points to keep in mind.

Officials anticipate raising big bucks from the sale of lovey-dovey padlocks removed from Paris' bridges.

Even in Paris, a city with a lot of love for its dogs, public green space has traditionally been off-limits.

The City of Lights is for lovers ... and pedestrians, bikers and transit riders.

A ban on gas and diesel cars is the latest in Paris Mayor Anne Hidalgo's ongoing crackdown on air pollution.

Michael Green, champion of lanky, carbon-neutral buildings, sets his sights on the City of Light.

France's most visited house of worship, the Notre Dame Cathedral, just seriously slashed its energy bills with the addition of 400 LED lamps.

Paris can be pretty unfriendly to tourists, but SmarterParis is a friendly new app that can make it easier.

Her application inspires Paris Summer Innovation Fellowship selection officials to look beyond age and take a chance on a kid with passion.

Paris may not be as green as other cities, but it's possible to enjoy a low-impact vacation in the City of Light.

Facing health alerts over smog and pollution, Paris tries to get its citizens out of their cars.

The U.S. retreat from the Paris Agreement is bad news for the world, but it could be even worse for the U.S. itself.

Sitting at the terrace of a sidewalk cafe in Paris and sipping on a Perrier while watching passers-by is a pleasure many travelers promise themselves to experience when they are in Paris. But with the check comes the question: to tip or not to tip?

Small Paris museums offer you an alternative to the large venues when you wish to avoid the crowds there. See which museums to visit here.

Competitive and fast are two terms that are applicable to the world of computers. Constantly changing and evolving computer systems bring many advantages to the users and techies alike. The race for supremacy between the yet to be launched Vista (scheduled for 2006) and Mac OSX Tiger began in 2003 with Microsoft's announcements of plans for an integrated desktop search functionality in Windows Vista.

February 15 - 18, 2019

Developer Invites Lovers to Partake in Ritual at Love Locks Mural in New Fort Worth Design District that Opens November 11, 2018

Le Choix du Consommateur 2019 Trois-Rivières