In a preliminary analysis, NASA researchers compared NO2 values detected by OMI in 2020 with the average amounts detected at this time of year from 2005-2019.

Curiosity's project scientist at NASA's Jet Propulsion Laboratory Ashwin Vasavada said that it is the first time that NASA has dedicated its operations to capture a 360-degree panorama.

Ever since Dragon became the first private spacecraft to visit the ISS in 2012, it had spent 520 days at the International Space Station

Coronavirus: A week ago, an employee at the NASA’s Ames Research Centre in California was tested positive for the virus.

The space rock will pass the earth at a distance 4.6 times of distance between the Moon and Earth.

The space agency is shutting down its Michoud Assembly Facility in New Orleans, where the Space Launch System rocket is being built, and the nearby Stennis Space Center, administrator Jim Bridenstine said late Thursday.

A total of 12,000 applicants applied to become astronauts at the National Aeronautics and Space Administration (NASA).

NASA astronaut Chris Cassidy along with two Russian cosmonauts Anatoly Ivanishin and Ivan Vagner reached the International Space Station (ISS) for a six-month-long mission named Expedition 63.

Termed "a successful failure", the spacecraft which had three astronauts- James Lovell Jr, Fred Haise Jr, and John Swigert Jr- on board managed to return to the Earth despite facing an explosion like situation after a blast in its oxygen tank.

The planet, being called Kepler-1649c, was discovered by the team when they were looking through the data of previous observations from the Kepler telescope, which had been retired by NASA in 2018.

Rupani, a high school junior from Northport, Alabama, earned the honour of naming the helicopter after she submitted her essay into NASA's "Name the Rover" contest.

During a virtual interaction, she compared the Indian students' experience to her being in space in a spacecraft “where you don't get to go, see your family and friends and give them a real hug.”

The institute has a high-level bio-safety facility designated Biosafety Level 3 Agriculture with the ability to safely handle and study pathogens like highly pathogenic influenza viruses and the novel coronavirus.

Fake Message: જનતા કર્ફ્યૂ સમયે તાળી અને થાળી વગાડવાના અવાજ બાદ એક સાઉન્ડ વેબ ક્રિએટ થયો અને કોરોના ભારતમાં નબળો પડી ગયો

નાસાને આવો ત્રીજો ગ્રહ મળ્યો છે જ્યાં જીવન હોવાની સંભાવના છે.

In a back room of Singaporean dentist Teehee Dental Works, three orange-topped boxes hum with a sterile buzz.Over the next three hours, a thousand strands of liquid resin will form and harden to become plastic nasal swabs, ready to be used in Covid-19 test kits. Those 3D printers – normally making dentures and crowns – are a part of a local effort to re-tool some of Singapore’s industries to respond to a growing need for test kits amid the widening coronavirus pandemic.With one of Asia’s…

A NASA engineer has published plans for an engine that could accelerate a rocket without using propellant. But there are questions over whether it could work

The unique metal asteroid Psyche may be a space miner's fantasy – but there are better reasons to want to visit it, says mission leader Lindy Elkins-Tanton

NASA on Thursday selected space firms SpaceX, Blue Origin and Dynetics to build lunar landing systems that can carry astronauts to the moon by 2024, the White House's accelerated deadline under the space agency's moon-to-Mars campaign. Jillian Kitchener has more.

NASA has awarded $967 million to three space flight companies – Blue Origin, Dynetics and SpaceX – to build lunar landers that will be part of the Artemis programme to send humans to the moon by 2024

ABSTRACT

Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012. There are currently no approved vaccines or therapies available for MERS-CoV. In this study, we evaluated parainfluenza virus 5 (PIV5)-based vaccine expressing the MERS-CoV envelope spike protein (PIV5/MERS-S) in a human DPP4 knockin C57BL/6 congenic mouse model (hDPP4 KI). Following a single-dose intranasal immunization, PIV5-MERS-S induced neutralizing antibody and robust T cell responses in hDPP4 KI mice. A single intranasal administration of 10⁴ PFU PIV5-MERS-S provided complete protection against a lethal challenge with mouse-adapted MERS-CoV (MERS_MA6.1.2) and improved virus clearance in the lung. In comparison, single-dose intramuscular immunization with 10⁶ PFU UV-inactivated MERS_MA6.1.2 mixed with Imject alum provided protection to only 25% of immunized mice. Intriguingly, an influx of eosinophils was observed only in the lungs of mice immunized with inactivated MERS-CoV, suggestive of a hypersensitivity-type response. Overall, our study indicated that PIV5-MERS-S is a promising effective vaccine candidate against MERS-CoV infection.

IMPORTANCE MERS-CoV causes lethal infection in humans, and there is no vaccine. Our work demonstrates that PIV5 is a promising vector for developing a MERS vaccine. Furthermore, success of PIV5-based MERS vaccine can be employed to develop a vaccine for emerging CoVs such as SARS-CoV-2, which causes COVID-19.

Localized skin lesions are characteristic of cutaneous leishmaniasis (CL); however, Leishmania (Viannia) species, which are responsible for most CL cases in the Americas, can spread systemically, sometimes resulting in mucosal disease. Detection of Leishmania has been documented in healthy mucosal tissues (conjunctiva, tonsils, and nasal mucosa) and healthy skin of CL patients and in individuals with asymptomatic infection in areas of endemicity of L. (V.) panamensis and L. (V.) braziliensis transmission. However, the conditions and mechanisms that favor parasite persistence in healthy mucosal tissues are unknown. In this descriptive study, we compared the cell populations of the nasal mucosa (NM) of healthy donors and patients with active CL and explored the immune gene expression signatures related to molecular detection of Leishmania in this tissue in the absence of clinical signs or symptoms of mucosal disease. The cellular composition and gene expression profiles of NM samples from active CL patients were similar to those of healthy volunteers, with a predominance of epithelial over immune cells, and within the CD45⁺ cell population, a higher frequency of CD66b⁺ followed by CD14⁺ and CD3⁺ cells. In CL patients with molecular evidence of Leishmania persistence in the NM, genes characteristic of an anti-inflammatory and tissue repair responses (IL4R, IL5RA, POSTN, and SATB1) were overexpressed relative to NM samples from CL patients in which Leishmania was not detected. Here, we report the first immunological description of subclinically infected NM tissues of CL patients and provide evidence of a local anti-inflammatory environment favoring parasite persistence in the NM.

BACKGROUND:High-flow nasal cannula (HFNC) therapy may reduce the re-intubation rate compared with conventional oxygen therapy. However, HFNC has not been sufficiently compared with conventional oxygen therapy with a heated humidifier, even though heated humidification is beneficial for facilitating airway clearance.METHODS:This study was a single-center, open-label, randomized controlled trial. We randomized subjects with respiratory failure after extubation to either HFNC group or to a large-volume humidified nebulization-based nebulizer. The primary end point was the re-intubation rate within 7 d after extubation.RESULTS:We could not recruit enough subjects for the sample size we designed, therefore, we analyzed 69 subjects (HFNC group, 30 subjects; nebulizer group, 39 subjects). The re-intubation rate within 7 d was not significantly different between the HFNC and nebulizer groups (5/30 subjects [17%] and 6/39 subjects [15%], respectively; P > .99). PaO2/set FIO2 at 24 h after extubation was also not significantly different between the respective groups (264 ± 105 mm Hg in the HFNC group vs 224 ± 53 mm Hg in the nebulizer group; P = .07).CONCLUSIONS:Compared with a large-volume nebulization-based humidifier, HFNC may not reduce the re-intubation rate within 7 d. However, because of insufficient statistical power, further studies are needed to reach a conclusion.

Stiff person syndrome (SPS) is a rare neurologic disorder characterized by progressively worsening rigidity and spasms of the axial and limb muscles. Dyspnea has been recently recognized as a common symptom in SPS,¹ and life-threatening respiratory crises have been occasionally reported and suspected to be responsible for sudden death in these patients.^2,3 The pathophysiologic mechanisms of these respiratory manifestations remain unclear. Some authors have hypothesized that rigidity and/or spasm of the muscles of the trunk could prevent normal rib cage movements and excursion of the diaphragm.¹

NASA’s Mars 2020 rover will search for signs of life on Mars, and New Scientist’s Leah Crane visited it in the clean room where it is being assembled

The TESS space telescope has found its first Earth-sized planet with conditions that might be right for life, orbiting a small star 100 light years away

The first US woman to spacewalk flew on three shuttle missions and says nothing beats space flight – but her proudest achievement is helping to repair the Hubble Space Telescope

NASA has selected four potential future missions – to Jupiter’s fiery moon Io, Neptune’s icy moon Triton, and two that would explore the atmosphere and map the surface of Venus

NASA’s InSight lander has been on the surface of Mars for over a year now – here are five of its strangest and most fascinating discoveries from the Red Planet

Out of 28,000 suggestions, NASA selected the name Perseverance for its Mars 2020 rover, which will search for signs of life on the Red Planet

NASA has awarded $967 million to three space flight companies – Blue Origin, Dynetics and SpaceX – to build lunar landers that will be part of the Artemis programme to send humans to the moon by 2024

Job postings from a NASA contractor suggest that a new humanoid robot is under development

The newly-remastered images show the icy surface of Europa, the sixth of Jupiter’s moons and the fourth largest, in enhanced color. All three high-resolution images were captured along the same longitude of Europa as NASA’s Galileo spacecraft flew by on September 26, 1998, in the eighth of the spacecraft’s 11 targeted flybys of the icy [...]