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State Library Council Awards declared, M. Leelavathy wins I.V. Das award for overall contributions




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Kalpathy car fest: a spectacle of faith and tradition

Chariots of the Sree Visalakshi Sametha Viswanatha Swamy temple start moving through the streets




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NIFT’s craft cluster projects enriching J&K’s artisans, crafts: L-G Manoj Sinha

He described J&K as “a repository of Indian creative traditions




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ED arrests four, including two Bangladeshi nationals, in human trafficking case




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India will continue to be vocal about climate finances at COP29




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Integrated manufacturing cluster to be developed in Bihar's Gaya




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India set to become 'major producer' of electric vehicles like China: Mark Mobius




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Coal import for blending purposes in power generation declines by 8.5% during April-Sept 2024




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Photocatalytic 1,3-Oxyheteroarylation of Aryl Cyclopropanes with Azine N-oxides

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06723A, Edge Article
Open Access
Doyoung Kim, Hyewon Ju, Wooseok Lee, Sungwoo Hong
Cyclopropanes, valuable C3 building blocks in organic synthesis, possess high strain energy and inherent stability. We present an efficient, environmentally benign 1,3-oxyheteroarylation of aryl cyclopropanes using azine N-oxides as bifunctional...
The content of this RSS Feed (c) The Royal Society of Chemistry




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BRO rescues 20 vehicles stuck in snow in J-K's Bandipora




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Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




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COP29: India, other developing countries demand fair climate finance commitments

India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments




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Lebanon media claims Israeli strike hit apartment south of Beirut

Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet




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Senior Russian naval officer killed in car bombing claimed by Kyiv

Russia's state Investigative Committee said in a statement that an improvised explosive device had detonated in an act of terrorism, killing a serviceman whom it did not identify




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In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP

RSC Med. Chem., 2024, 15,3674-3694
DOI: 10.1039/D4MD00580E, Research Article
Jinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin Jin
Oridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site

RSC Med. Chem., 2024, 15,3704-3710
DOI: 10.1039/D4MD00552J, Research Article
Jaeyong Jung, Jeong Soo Sung, Soonil Kwon, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul Pyun
Fv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery

RSC Med. Chem., 2024, 15,3695-3703
DOI: 10.1039/D4MD00546E, Research Article
Miyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke Demizu
A novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Four Swedish companies, including IKEA, looking to set up base in Tamil Nadu: Swedish Ambassador to India

There are 70 Swedish companies in Tamil Nadu, employing about 25,000 people. But we want to do more, says Jan Thesleff




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U.S. oil industry urges Trump to ditch Biden climate policies




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Developed nations need to triple their contribution to make climate finance credible: Avinash Persaud

Currently, developed nations are expected to pay $100 billion a year but they haven’t stuck to agreed targets, and this system ends next year.




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PAG report points out Andhra Pradesh govt.’s failure to disclose quantum of off-budget borrowings in Budget

Principal amount outstanding in 2019-20 was ₹67,171 crore, and it touched ₹1,54,797 crore in 2023-24, says the PAG report released by the I&PR Department




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Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




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Why are countries fighting over climate finance at COP29?

Here is what you need to know about the November 11-22 summit talks on finance.




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COP29: India, other developing countries demand fair climate finance commitments

India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments




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29th Climate Conference (COP) tracker | Day 2 LIVE: Key speeches, UK NDC, and India’s reaction at 5 p.m. on November 13

Vibhuti Garg, an Associate and Senior Energy Specialist with over 13 years of experience in the energy sector, will guide us through the implications of these financial negotiations and the potential impacts on global energy transitions and climate commitments at 5 p.m. on November 13




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PUCL condemns opposition to Dalits’ entry into temple in Mandya village




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Kalaburagi city police arrests 30 vehicle lifters, recovers 105 motorbikes




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Three youths go missing after coracle overturns in Sharavathi backwaters in Sagar taluk




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India's middle class tightens its belt, squeezed by food inflation

Slowing urban spending over the past three to four months has not only hurt the earnings of largest consumer goods firms




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IL&FS debt resolution: NCLAT sets March 2025 deadline to lift moratorium on IL&FS entities

Some of the lenders had sought the tribunal’s approval to start proceedings under IBC for recovering dues from the 58 IL&FS entities




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The globally-acclaimed Candlelight Concert is now in Chennai. Listen to classical and contemporary music at Museum Theatre, amidst thousands of candles

The first concert on November 15 will feature tunes from Tamil and Hindi films, followed by tributes to Coldplay, Mozart, Queen, and Abba in the upcoming months



  • Life & Style

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Pakistan court acquits Imran Khan, his close aides in Section 144 violation case

The dismissal of the case against Khan comes as a kind of relief for someone who has been incarcerated since August last year




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Cochin Shipyard funding for climate tech company




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How the Supreme Court clamped down on ‘bulldozer’ demolition drives | Explained

The top court has issued a slew of guidelines aimed at ensuring institutional accountability to curb retributive demolitions by state authorities




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‘Unwieldy’ first draft at Baku sets 2030 goal of $5 trillion for climate action

While there are multiple technical issues being deliberated upon at Baku, the headline-moment that the hundreds of negotiators are working upon, is the NCQG.




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Extra coaches to clear waiting list in some trains

The Railways have requested passengers to avail of the services of the extra coaches




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Encroached lands to be cleared to make way for sports grounds in Thoothukudi




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COP29: India, other developing countries demand fair climate finance commitments

During the negotiations, the LMDCs emphasised the principle of “common but differentiated responsibilities” (CBDR) to address the pressing financial gaps hindering effective climate action




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Explained: What is climate change and why is the world meeting at COP29?




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South Africa declares National Disaster after floods, storms

Disruptive rains, floods, strong winds and hail from Oct. 22 to Oct. 29 affected the Eastern Cape, KwaZulu-Natal, Free State, Limpopo, North-West, Gauteng and Mpumalanga provinces, Elias Sithole, head of the National Disaster Management Centre




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All options, including exit, open for Siemens Gamesa India, says CEO 

CEO Bruch emphasises India’s value, yet exit remains a possibility




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Torrent Power reports 8.5% decline in Q2 net profit

Its revenue from operations rose 3 per cent to ₹7,176 crore in the second quarter




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R K Swamy’s Q2 profit decline, announces new customer facility launch

Shekar Swamy, Group CEO, said that despite the dip in revenue, the company’s new business pipeline remains strong




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FinMin not keen on inclusion of BIT in free trade pacts: Sources

FTA investment chapters may be limited to investment promotion, facilitation




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Green Frontier Capital launches ₹1,500 cr fund for climate tech start-ups

The fund will focus on accelerating India’s low-carbon transition through investments in transformative climate technologies




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Tata Chemicals to invest £60 million in UK sodium bicarbonate plant, close Lostock unit 

The new facility will have an annual production capacity of 180,000 tons, tripling TCEL’s current pharmaceutical-grade sodium bicarbonate production capacity in the UK




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Rupee rises 1 paisa to close at 84.38 against US dollar

Rupee weighed down by foreign fund outflows, domestic equities




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ATP Finals: Ailing Alcaraz outclasses Rublev

Spain's Carlos Alcaraz made light of feeling under the weather as he dispatched Russia's Andrey Rublev in impressive fashion to revive his ATP Finals hopes on Wednesday.




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PSBs clocked 11% growth in H1FY25

The Union Finance Ministry on Tuesday said that aggregate business of public sector banks (PSBs) has shown strong growth of 11 per cent in the first half of the financial year 2024-25 (H1FY25) to touch Rs 236 trillion. The operating and net profit were also robust. At Rs 1.5 trillion, operating profit grew by 14.4 per cent year-on-year (Y-o-Y) while the net profit saw an impressive 25.6 per cent jump at Rs 85,520 crore in the first half of FY25.




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Chrome Update to Kill Many Addons, including Blockers

Almost one in six Chrome extensions could stop working this summer thanks to a major Google update. They include one of the most prominent ad-blocking tools. An extension is a third party tool that integrates with Chrome to improve the user's experience when accessing websites. They can include tools as diverse as password managers, page translators and video downloaders, though ad blockers are perhaps the best known. Extensions are able to integrate with Chrome and access its data thanks for a platform called Manifest. Google has developed a Version 3 of Manifest and is phasing out support ... (view more)