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Takeda finally snags Shire in $62 billion deal

If successful, the transaction could spur more M&A among major drug firms




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Osmosis could prevent noise-induced hearing loss

Loud blasts, such as those from roadside bombs, can cause damaging fluid buildup in inner ear, according to study in mice




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Polymers and composites made incredibly cheaply

Frontal polymerization approach reduces energy use significantly




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Reactions




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Genentech and Lodo team to discover natural products




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Merck and Moderna sign cancer vaccine deal




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German premier Angela Merkel marks Merck’s 350 years




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Changing of the guard at European chemical firms

BASF, Borealis, Covestro, and Solvay bring in new CEOs as they report first-quarter results




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SOCMA head Jennifer Abril wants to take the trade association back to its roots

The nontraditional leader of the specialty chemical manufacturers’ association wants to steer it back to its traditional values




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David Liu launches Beam Therapeutics to treat genetic diseases with CRISPR base editing

Joined by CRISPR luminaries Feng Zhang and J. Keith Joung, the Harvard chemist raises up to $87 million in funding




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Can single-cell genomics lead to a new wave of drug targets? Celsius Therapeutics thinks so

The start-up, based on the work of Broad Institute scientist Aviv Regev, has raised $65 million to develop therapies for cancer and autoimmune disease




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Tellurium contamination, on the rise, travels to remote areas from industrial sources

As demand for the rare element grows, researchers trace the history of long-range tellurium deposition 




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CAS names its 2018 CAS SciFinder Future Leaders

CAS selects Ph.D. and postdoctoral researchers to help shape scientific information




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Rise in CFC emissions threatens ozone recovery

Rogue trichlorofluoromethane likely originates from production facilities in East Asia




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When a great researcher isn’t a great person




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ACS’s educational outreach: When rain gives way to flowers




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China’s Tianqi to get stake in Chilean lithium maker SQM




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Gilead’s Kite adds cell therapy manufacturing capacity




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David Liu launches Beam Therapeutics to treat genetic diseases with CRISPR base editing

Joined by CRISPR luminaries Feng Zhang and J. Keith Joung, the Harvard chemist raises up to $87 million in funding




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Tellurium contamination, on the rise, travels to remote areas from industrial sources

As demand for the rare element grows, researchers trace the history of long-range tellurium deposition




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Hanford researchers demonstrate continuous process to vitrify waste from nuclear weapons production




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Release of U.S. study on health effects of perfluorinated compounds sought




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EPA gears up for controlling poly- and perfluorochemical pollution

Agency plans legal limit on four PFASs in drinking water, creating liability for PFOS and PFOA contamination




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Enzyme catalyzes cross-membrane reaction

Hydrophilic and hydrophobic molecules don’t have to leave their natural environments to react




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Chemists claim they’ve defined the first new class of stereoisomers in 50 years

Akamptisomers result from bond-angle inversion




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Bloom Science launches to treat epilepsy with ketogenic diet-associated gut microbes

The start-up wants to develop treatments based on two kinds of bacteria linked to the antiseizure effects of the ketogenic diet




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Chemical firms rush to meet final REACH regulation deadline

Products made in volumes between 1 and 100 metric tons must be registered by May 31




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U.K. will pay to play in EU science research

Prime minister wants to maintain full participation in Horizon Europe




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U.S. EPA proposes final pollution cleanup plan for American Cyanamid site

Goal is getting Pfizer-owned land in New Jersey back into use




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Don’t freak out, Europe, but you might be in the middle of a mustelid uprising




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Chemistry in Pictures: ‘Dusty peacock’




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How an opossum protein may lead to a broad-spectrum snakebite treatment

San Jose State’s Claire Komives is testing an antivenom inspired by opossum biochemistry against various snake species to prevent deaths in the developing world




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Discovery of new poppy enzyme might help improve yeast-based opiate synthesis

Adding enzyme to engineered yeast boosts production of thebaine, a key morphine intermediate




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Experimental cancer cell therapies have nearly doubled in six months

A new report from the Cancer Research Institute highlights the U.S. and China as cell therapy leaders




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The difficult search for the right recipe in cancer immunotherapy

With so many ingredients on hand, can the oncology community figure out how to sensibly and efficiently combine checkpoint inhibitors with other drugs?




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CRISPR researchers receive Kavli Prize in Nanoscience

Emmanuelle Charpentier, Jennifer Doudna, and Virginijus Siksnys win Kavli Prize in nanoscience, renewing Nobel Prize speculation and resurfacing a forgotten name in the CRISPR patent battle




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CAS names its 2018 CAS SciFinder Future Leaders




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Bloom Science launches to treat epilepsy with ketogenic-diet-associated gut microbes

The start-up wants to develop treatments based on two kinds of bacteria linked to the antiseizure effects of the ketogenic diet




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U.S. clears Bayer’s acquisition of Monsanto




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U.S. EPA proposes final pollution cleanup plan for American Cyanamid site

Goal is getting Pfizer-owned land in New Jersey back into use




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Cortexyme raises $76 million to test bacterial protease inhibitor in Alzheimer’s




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U.S. industries ask Trump administration to endorse global hydrofluorocarbon deal

With EPA regulation overturned in court, companies seek political backing for reducing HFC use domestically




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Air pollutants in India kill more than 400,000 people a year in urban and rural areas

Sources of pollution differ but models predict more deaths in rural areas because of higher populations there




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Sensing molecules released from single cells without labels

Combination of microfluidics and a nanosensor achieves label-free detection of cytokines from individual cells




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Bleach activator could lead to greener whites

Cationic molecule helps bleach cotton faster with less energy




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Showcasing science’s role in addressing plastic in oceans

International exhibition visits Washington, D.C.




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New York State requires disclosure of cleaning product ingredients




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Reporting required for U.S. releases of 13 nonylphenol ethoxylates

Group of surfactants linked to toxicity in aquatic organisms