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Breaking boundaries in diabetic nephropathy treatment: design and synthesis of novel steroidal SGLT2 inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00645C, Research Article
Geetmani Singh Nongthombam, Semim Akhtar Ahmed, Kangkon Saikia, Sanjib Gogoi, Jagat Chandra Borah
Virtual screening and synthetic modification of natural product-derived steroidal precursors as potential SGLT2 inhibitors for the treatment of diabetic nephropathy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Heavy weed growth at Kasi Viswanathar Temple tank prevents replenishing of underground water table, say Tiruchi residents




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EPS’s dream of AIADMK staging a comeback in 2026 election will not materialise: Law Minister Regupathy




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Lack of signboards indicating bus timings at Chathiram Bus Stand in Tiruchi irks passengers

Passengers also say some buses leave earlier than scheduled or don’t pass certain rural areas, leading to schoolchildren not being able to board on time




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543: Zach Leatherman on Eleventy, Mastodon, Twitter, and is-land

Zach Leatherman talks with us about what's new with Eleventy, setting up on Mastodon, what's happened with Twitter, and is-land.




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‘We want our citizens to breathe fresh air’

Dr. John Keung, CEO of Singapore’s Building and Construction Authority, plans to convert 80 per cent of all buildings in his country to green buildings by 2030.




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Galathea Bay: New major port can be game changer

Transshipment port at Galathea Bay is strategically located on the East-West international trade and shipping route




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Govt., BJP spar over Chhath planning as festivities begin today




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Chhath Puja: Devotees take dip in Yamuna even as toxic foam floats over river  




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Delhi HC seeks CBI’s response on plea to preserve CCTV footage in coaching centre deaths




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Chhath Puja: BJP, Cong. slam Delhi govt. over bad air, water




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Yamuna highly toxic, says Delhi HC, bins plea to allow Chhath Puja rituals on riverbanks

Court dismisses petition against order prohibiting Chhath Puja rituals on Yamuna’s banks, says it can’t let devotees fall sick; have made ample arrangements at 1,000 ghats: Delhi govt. counsel; 4-day festival dedicated to Sun God began on Tuesday




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Devotees throng Delhi ghats, mark Chhath Puja festivity with prayers, songs, selfies

Lakhs of devotees offer ‘Sandhya Arghya’ to the setting sun on the third day of the four-day festival; political leaders make a beeline for ghats with an eye on Purvanchali voters ahead of Assembly poll




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Forging a distinctive path

Ensuring women-centric workplaces




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‘India has carved out its own path in foreign policy’

In his new book, former diplomat Vijay Keshav Gokhale throws fresh light on India-China relations since Independence




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M.S. Swaminathan, the scientist who sliced potatoes

Not once did the ‘Rice Man of India’ keep his publisher waiting




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T.N. CM Stalin announces naming of Thanjavur Agricultural College after late scientist M.S. Swaminathan

In an announcement made in the Legislative Assembly on Wednesday, the CM, praising the renowned agricultural scientist’s contributions, also said a student award would be instituted under his name




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Centre launches new system to understand cropping patterns, impact of weather

Union Agriculture Ministry launches Krishi-DSS, a digital platform providing real-time data insights for stakeholders in Indian agriculture




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Centre talks to States on new mechanism to gather crop data

The national conference discusses the Digital General Crop Estimation Survey to enhance agricultural statistics accuracy and transparency for policy formulation and planning




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Observability and mathematics [electronic resource] : Quantum Yang-Mills theory and modelling / Boris Khots.




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Saidapet-Teynampet elevated corridor project: Highways Dept. removes footpaths on Anna Salai to construct flyover

The removal of the footpaths will help increase the width of the carriageway at points where lanes on either side of the median will be barricaded




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Thickness-dependent response of aerosol-jet-printed ultrathin high-aspect-ratio electrochemical microactuators

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00886C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ji Zhang, Jeremy J. Baumberg, Sohini Kar-Narayan
Trilayer electrochemical actuators comprising an electrolyte layer sandwiched between two electrode layers have been shown to exhibit large deformations at low actuation voltages. Here we report aerosol-jet printing (AJP) of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Love affair with leather

Designer Sonal Verma tells us how leather craftsmanship is giving her a push into the world of fashion




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Mahila Praharis of the BSF Camel Contingent will make their Republic Day parade debut in uniform designed by Raghavendra Rathore

The designer also incorporated various skills from across the country and it took him three months to complete the uniform



  • Life & Style

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Chronicles of a triathelete

Anu Vaidyanathan talks about her journey as a triathelete in her memoir Anywhere but Home




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Coimbatore-based Walkaroo footwear hosts the 11th edition of Coimbatore Marathon

Coimbatore-based Walkaroo footwear has joined hands with Coimbatore Cancer Foundation to host the 11th edition of the Coimbatore Marathon




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Turnaround : A Story of Recovery / directed by: Moira Simpson ; produced by: Jennifer Torrance, Moira Simpson, John Taylor, Kathleen Shannon ; production agency: National Film Board of Canada (Montreal)

Montreal : National Film Board of Canada, 2017




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Kímmapiiyipitssini : The Meaning of Empathy / directed by: Elle-Máijá Tailfeathers ; produced by: Elle-Máijá Tailfeathers, David Christensen, lori lozinski, David Christensen ; production agencies: Seen Through Woman Productions (

Montreal : National Film Board of Canada, 2022




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Leopard killed in road accident in Sri Sathya Sai district




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Endowments Secretary and Commissioner takes oath as ex-officio member of TTD Trust Board




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Andhra Pradesh Budget is deceptive, says Buggana Rajendranath

How can the government fulfill its poll promises with a meagre increase in budgetary allocation of ₹24,000 crore, questions the former Finance Minister




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Child mauled to death by stray dogs in A.P.’s NTR district

Vijayawada Parliament Member, Kesineni Sivanath, SCPCR Chairman Kesali Appa Rao expressed concern over the death of the boy, directs VMC, Panchayat Raj officials to take steps to prevent dog menace




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Maharashtra elections 2024: On Maratha reservation, there is near social consensus

There is no battle between the Marathas and the OBCs on the issue of reservation to Marathas, as of now




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Luck, logic, and white lies [electronic resource] : the mathematics of games / Jörg Bewersdorff ; translated by David Kramer.

Boca Raton, FL : CRC Press, 2021.




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Compact Riemann surfaces [electronic resource] : an introduction to contemporary mathematics / by Jürgen Jost

Berlin ; Heidelberg : Springer-Verlag Berlin Heidelberg, 2006




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Uniform output regulation of nonlinear systems [electronic resource] : a convergent dynamics approach / Alexey Pavlov, Nathan van de Wouw, Henk Nijmeijer

Boston : Birkhäuser, 2006




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Growing mathematical minds [electronic resource] : conversations between developmental psychologists and early childhood teachers / edited by Jennifer S. McCray, Jie-Qi Chen, and Janet Eisenband-Sorkin.

New York, NY : Routledge, 2019.




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Illustrating mathematics [electronic resource] / Diana Davis, editor.

Providence, Rhode Island : American Mathematical Society, [2020]




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Fuchsian reduction [electronic resource] : applications to geometry, cosmology and mathematical physics / Satyanad Kichenassamy

Boston : Birkhauser, 2007




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Topological and bivariant K-theory [electronic resource] / Joachim Cuntz, Ralf Meyer, Jonathan M. Rosenberg

Basel ; Boston : Birkhauser, 2007




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Probability and partial differential equations in modern applied mathematics [electronic resource] / Edward C. Waymire, Jinqiao Duan, editors

New York : Springer, [2005]




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Problems and theorems in classical set theory [electronic resource] / Peter Komjath, Vilmos Totik

New York ; Berlin : Springer, 2006




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Number theory and combinatorics [electronic resource] : a collection in honor of the mathematics of Ronald Graham / edited by Bruce M. Landman, Florian Luca, Melvyn B. Nathanson, Jaroslav Nešetřil, and Aaron Robertson.

Berlin ; Boston : De Gruyter, [2022]




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The splendors and miseries of martingales [electronic resource] : their history from the casino to mathematics / Laurent Mazliak, Glenn Shafer, editors.

Cham : Birkhäuser, 2022




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Basic gambling mathematics [electronic resource] : the numbers behind the neon / Mark Bollman

Boca Raton : CRC Press, Taylor & Francis Group, 2024




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Kannada Ratha gets rousing welcome in Udupi district

Ratha with Kannada Jyothi has been touring Karnataka ahead of the Mandya sahitya sammelana




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Traffic restrictions in place till 10 a.m. of November 10 for Mangalore Marathon

The Mangalore Marathon comprises of 42K, 32K, 21K, 10K, 10K students run, 5K, 5K student run and 2K Gammat run between Mangala Stadium and Tannirbhavi second beach




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Samithi to hold collective dharna on November 26 demanding complete restoration of Nanthoor-Surathkal stretch of NH 66

Preparatory meeting highlights battered carriageway stretch, absence of service roads and shoulder drains and delayed execution of new bridge at Kulur




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Kudla Samskrutika Prathishtana to hold ‘Mangaluru Street Food Festival’ from January 15 to 19




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Over 5,000 runners register for Mangalore Marathon on November 10