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Testing times for the American soccer revolution

‘The hopes of soccer bulls have been dashed again. The US team has crashed out of the World Cup’




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A modest proposal: time to rethink the impact of US tax reform




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My First Million: Matt Kay, founder of Cartime

He used student loan to finance first car deal, and company now turns over £40m




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Jack Whitehall and Roxy Horner are seen kissing for the first time during romantic stroll

The comedian, 31, and the model, 28, looked like they were on cloud nine as they shared a smooch while strolling hand-in-hand through the city.




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Kareena Kapoor Khan's goofy picture with little Tim is the best thing on internet today!

Kareena Kapoor Khan's goofy picture with little Tim is the best thing on internet today!





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Covid-19: Assam has stepped into most difficult times, says health minister Himanta Biswa Sarma




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Charitable & Religious Trusts Allowed More Time For Registration Compliance

The CBDT (Central Board of Direct Taxes) has extended the period of re-registering charitable and religious trusts under the Finance Act 2020 to 1 October. In the view of the unprecedented outbreak of COVID-19 that has caused a humanitarian and economic




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Charitable & Religious Trusts Allowed More Time For Registration Compliance

The CBDT (Central Board of Direct Taxes) has extended the period of re-registering charitable and religious trusts under the Finance Act 2020 to 1 October. In the view of the unprecedented outbreak of COVID-19 that has caused a humanitarian and economic




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Five Times Sara Ali Khan Treated Us With Her Gorgeous Distinctive Ethnic Outfits And Gave Us Goals

Bollywood actress Sara Ali Khan has captured the hearts of the audience with her charming personality and acting prowess. Apart from it, her sartorial picks has also left us stunned. Be it events or festivals, the diva has been giving




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Dulquer Salmaan Gears Up For A Telugu Movie After Mahanati, This Time For A Romantic-Thriller!

Dulquer Salmaan, one of the most talented actors of the South film industry is all set to embrace Tollywood. Known for his charismatic persona, the actor is gearing up for a second Telugu film after his incredible debut in Mahanati. According




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Brahms and the shaping of time / edited by Scott Murphy

Lewis Library - ML410.B8 B655 2018




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An accurate free energy estimator: based on MM/PBSA combined with interaction entropy for protein–ligand binding affinity

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10638C, Paper
Kaifang Huang, Song Luo, Yalong Cong, Susu Zhong, John Z. H. Zhang, Lili Duan
Modifying the energy term and considering the entropic contribution by IE method significantly improve the accuracy of predicted binding free energy in MM/PBSA method.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Time for textiles industry to reorient, stop seeking packages, says Smriti Irani

Union Minister Smriti Irani on Sunday asked the textile industry to reorient itself and not depend on financial packages from the government as its fi




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How five Canberrans are marking Mother's Day in the time of COVID-19 - The Canberra Times

  1. How five Canberrans are marking Mother's Day in the time of COVID-19  The Canberra Times
  2. Eight Australian mothers share the greatest thing their kids have taught them  ABC News
  3. Mother's Day: Our special mums - your stories  New Zealand Herald
  4. Mother's Day: Jacinda Ardern shares heartwarming message in celebration of her mum  Newshub
  5. Mum, in memory: A Mother's Day Tribute  New Straits Times
  6. View Full coverage on Google News




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Time Loops

Have you ever formed a time loop while tying your shoes? Probably not. But have you ever read a book or watched a TV show or film where someone experienced a day over and over again? It's more than déjà vu -- it's actually happening on repeat, sometimes with different results, sometimes with the same results, and it seems as if it will never stop repeating - until, of course, the character finds a way to make it stop.

Time loops are not to be confused with time travel, another of my favorite sci-fi plot devices. In time travel, one moves forward or backward in time, willingly or otherwise. Doctor Who has time travel. The Boys are Back in Town by Christopher Golden has time travel. Groundhog Day, however, has a time loop. This film is so well-known that he is often referenced by characters experiencing time loops; more than once, I've read or heard a character say, "This is like Groundhog Day," rather than, "Gee, I'm experiencing a time loop!"

Many movies and television shows have explored time loops. Consider, if you will, the episode "Shadow Play" on The Twilight Zone, the Buffy the Vampire Slayer episode "Life Serial," "Monday" on The X-Files, Supernatural's "Mystery Spot," or "And Those We've Left Behind" on Fringe. Some of these loops have been comedic, others dramatic, with the best ones (in my opinion) being those which deftly mix the two.

Another clarification: Plots such as those in the television series Tru Calling and Seven Days (the latter of which I sadly never saw when it aired) weren't considered to be true time loops: both shows had worked off of a second-chance premise, with Tru repeating a day in attempt to save someone's life, while Frank used the Chronosphere (also known as the Backstep Sphere) to go back in time seven days to "avert disasters."

I really enjoyed Before I Fall by Lauren Oliver, an intriguing and inventive novel in which the main character, Samantha (Sam), is killed in an accident only 80 pages into the book - then wakes up in bed, unharmed, only to find that it's not the next day - instead, it's the same day, the morning of her last day. She relives the day, bewildered and disbelieving. That evening, tragedy strikes again. The day repeats again, and again, a few times over. Sam does different things each time, spending one day being more cautious, another throwing caution to the wind, still another being more appreciative. It's an amazing book, and I highly recommend it. (And no, I haven't seen the movie yet.)


Like the novel The Time Traveler's Wife, Before I Fall has no overt sci-fi elements: there are no gadgets or gizmos or time machines that the characters use, accidentally or otherwise. Neither of those books have wizened characters who assist the protagonists with magic or explain the rules of the game to them. Instead, Henry and Sam have to figure things out (or make things up) as they go along. However, while Henry has Clare to confide in, Sam tells no one; while Henry travels through time involuntarily, Sam keeps repeating the same day involuntarily.

The NeverEnding Story by Michael Ende, the fantasy novel that has owned a piece of my heart since childhood, also employs a time loop. It is not the main plot, but rather just one of the many pieces of this elaborate and imaginative story. I don't want to give anything away; I'd rather encourage you to pick up the novel and discover things yourself. Whether or not you've seen The NeverEnding Story movie (which I think is wonderful) or the subsequent sequels or other film/TV attempts based on the book (which didn't compare), I implore you to read the original book.

Now, if you want to get technical, I haven't read the original, Die unendliche Geschichte, because it's in German, which I don't know. Instead, I've read the English translation by Ralph Manheim.

But I digress. Time loops are delicate things which not always treated so delicately, nor do they always have to deal with delicate matters. Time loops are not always handled or broken in the same way. Sam's story in Before I Fall is nothing like Phil's in Groundhog Day, and when they finally break their loops, they do so in completely different ways. The parameters and circumstances established by Danny Rubin in Groundhog Day do not apply to Sam. Likewise, though concepts such as chaos theory, the butterfly effect, and fate are discussed to different degrees in many time loop stories, they are never exactly the same - unless, of course, you personally choose to read that book or watch that episode or movie over and over and over again - which, in some cases, I wouldn't blame you for doing! When they're really inventive and strong, time loop stories can be fascinating. Some of these stories benefit from a second reading or viewing, because you notice things you may not have noticed the first time through.

Having a lackluster weekend? Go read or watch someone dealing with a time loop. Afterwards, you'll probably be happy that you are moving in a forward direction . . . or are you?




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Medium-intensity earthquake strikes Delhi, adjoining areas; 3rd amid Covid-19 lockdown - Hindustan Times

  1. Medium-intensity earthquake strikes Delhi, adjoining areas; 3rd amid Covid-19 lockdown  Hindustan Times
  2. Earthquake of magnitude 3.5 hits Delhi-NCR  Times of India
  3. Earthquake in Delhi: Tremors felt in national capital region  The Financial Express
  4. Magnitude 3.4 Earthquake Strikes Delhi, Epicentre Near UP Border  News18
  5. Breaking news live : Eathquake tremors felt in Delhi, adjoining areas  Times of India
  6. View Full coverage on Google News




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The Ultimate Mail Box Fix

What do you do when you put your mail box too close to the road?







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The Zombie Grinder 4000 Slingshot: The Ultimate in Anti-Undead Technology




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Sky Time Lapse WIN

What better way to start your day than by checking out some of the cool things you probably missed at night?







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TimTales: Robert Royal and Felix Hain

Felix‘s hole feels a little tighter no? Pobrecito had broken his arm when rollerblading and is now recovering. So now he needs to catch up on all the cock he’s missed. Robert Royal, TimTales‘ flavor of the month has one beautiful long raw cock waiting for him. Time for Felix to get a little physical... View Article

The post TimTales: Robert Royal and Felix Hain appeared first on QueerClick.




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Researchers create 'time crystals' envisioned by Princeton scientists

Theories developed at Princeton University led to the creation of time crystals reported in the journal Nature March 9 by two groups of researchers based at Harvard University and the University of Maryland. Time crystals feature atoms and molecules arranged across space and time and are opening up entirely new ways to think about the nature of matter. They also eventually may help protect information in futuristic devices known as quantum computers.




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Colorado shooting victim now focused on helping others




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First-time ‘panic’ gardeners flood Utah nurseries during coronavirus pandemic




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The Great Mother within: A time for us to summon her

“A mother has no age,” the rabbi said as a masked handful of us buried my grandma in Queens last week. The next day, my friend lost her mom to COVID-19 after a weeks-long battle with the illness.




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Brooklyn man arrested for molesting eight women, including six victims groped in one day: police

Nearly all of the assaults occurred on Thursday along the border of South Williamsburg and Bedford-Stuyvesant between 9:55 and 11:15 a.m., cops said.




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New York moms just want time to breathe this Mother’s Day

Many mothers are pulling double and triple duty caring for kids, juggling jobs, homeschooling, navigating financial hardship and acting as unofficial family doctor at time with unprecedented health concerns.




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New York moms just want time to breathe this Mother’s Day

Many mothers are pulling double and triple duty caring for kids, juggling jobs, homeschooling, navigating financial hardship and acting as unofficial family doctor at time with unprecedented health concerns.




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New York moms just want time to breathe this Mother’s Day

Many mothers are pulling double and triple duty caring for kids, juggling jobs, homeschooling, navigating financial hardship and acting as unofficial family doctor at time with unprecedented health concerns.




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Man tased four times during Friday arrest: RPS

Police used a taser several times during the arrest of a man on Friday.




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The Ultimate Guide to the Best Peruvian Beaches

When someone mentions “Peru,” images of bucolic mountain pastures, ancient Incan ruins, and verdant Amazonian jungle are probably the first thing that pop into your mind. But this beautiful South American nation boasts miles and miles of gorgeous Pacific coastline, and it is also home to some amazing beaches. Let’s take a look at some of best beaches Peru has to offer.

Cabo Blanco: Arguably the most famous beach along Peru’s 2,500 kilometers of coastline, Cabo Blanco is routinely hailed as one the best surf spots in the world. When Peruvian surfer Gordo Barreda was scouting the area for great waves, he randomly paid a visit to the village, where he stumbled upon the now famous Peruvian Pipeline. A hollow, powerful left-hanging wave, it is arguably one of the best places to catch a wave on the continent’s entire Pacific coastline. Even before Barreda’s famous discovery, this fishing hamlet long enchanted visitors with its small-town charm and thriving fishing industry. In the 1950s and 1960s, fishermen routinely made the trek to Cabo Blanco in search of the area’s legendary large marlin. The famous writer Ernest Hemmingway spent several months here during the filming of the movie adaptation of his novel “The Old Man and the Sea.” During his stay, he reportedly caught a 700-pound marlin.

Mancora: Once a quaint fishing village, Mancora has exploded onto Peru’s backpacker scene as a major hub in the last decade or so. Located right in the middle of Peru’s sunniest and warmest region, you can relax on beautiful beaches during the day and then party the night away. Mancora is great for travelers on a budget, and cheap hostels abound.

Vichayito: If you want great beaches without a slew of rowdy partiers, Vichayito is an excellent option. Situated about 7 kilometers to the south of Mancora, this is an ideal spot for families. The water is ideal for swimming and kite surfing, and the beaches are clean and quiet.

Punta Hermosa: Just an hour drive from Peru’s capital, Punta Hermosa is popular with Limeños looking for a summer retreat from the city. While not as spectacular as the beaches of Paracas or Mancora, Punta Hermosa’s proximity to Lima makes it a great option for looking for a quick weekend escape from the city.

Asia: Peru’s most opulent beach, Asia is all about glitz and glamour. The upper echelons of Peruvian society have luxurious summer homes at this beach resort town, making it a hub of wealth. The beaches are great, but what really make Asia stand out are its high-end restaurants, luxury shopping center, and dazzling nightclubs.

Paracas: The Paracas National Reserve boasts some of Peru’s most dramatic desert landscape. Here, enormous sand dunes and dramatic sandstone rock formations meet the azure waters of the Pacific. The reserve, which consists of a total of 335,000 hectares of tropical desert on the Paracas Peninsula, is intended to preserve the area’s rich marine ecosystem as well as protect its unique cultural heritage (the site was of great significance to the Paracas, a pre-Colombian indigenous group that inhabited the area between roughly 800 BC and 1000 BC). There are no formal hotels within the reserve, though there are many sites popular with beach campers.

If you are looking for more luxurious accommodations, they can certainly also be found. Though beach destinations to the north of the country often attract the majority of tourist attention, it is Paracas where you will find the most luxurious beach vacations Peru has to offer. Just a few miles from the park’s entrance, you will find Hotel Paracas, a Luxury Collection Resort complete with 5-star accommodations, three pools, and a luxury spa.

Marcona: For those really looking to get off of Peru’s beaten tourist trail, we recommend a visit to the rugged, windswept beaches of Marcona, located roughly 8 hours south of Lima. The waters here can be quite cold year-round thanks to the Humboldt current, which brings water up from Antarctica along the Pacific coast of Chile and southern Peru. But the cold temperatures mean that waters are teeming with marine life. With any bit of luck, visitors might catch a glimpse of one of the zone’s enormous seal colonies. The beaches are known for their dramatic rock formations and rough surf, but they are a great place for those looking for options totally free of tourists.

Courtesy of flickrhivemind.net

So they you have it, our pick of the best Peruvian beaches. Happy adventuring in Peru!



  • Places To See and Stay
  • Tips and Things To Know

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6 Ultimate Inca Trail Highlights

One of the most popular hikes in South America, the Inca Trail is definitely the experience of a lifetime. A centuries-old trail, it begins in the ancient Incan capital of Cusco and winds some 88 kilometers to some of the world’s most iconic ruins: Machu Picchu. Of course, the entirety of Inca Trail is absolutely stunning, from stunning snowcapped Andean peaks to centuries-old ruins situated in bucolic river valleys. However, these 5 highlights are truly bound to make your jaw drop.

Wayllabamba. The endpoint of the first day’s trek along the Inca Trail, Wayllabamba, which means “grassy plain” in Quechua, is the perfect spot to watch the sunset behind the dramatic Andean peaks. This grassy plain overlooks a stunning spot of Andean scenery, with centuries-old Incan terraces winding through the surrounding mountainsides. There is even a village nearby where travelers can mingle with local villagers.

Image courtesy of flatfootedadventurer.com

The Valley of Llulluchapampa. Trekkers will start off the first portion of day two of the journey hiking through the picturesque Valley of Llulluchapampa. As you gradually ascend in altitude, you will even be afforded perfect views of stunning snowcapped cliffs.

Image courtesy of Panoramio.com

Runkuracay: This unique oval structure, sometimes colloquially know as the “Egg Hut,” is believed to have been a kind of rest stop for Incan travelers, called a tambo, providing them with a place to spend the night and rest their animals. It is the perfect place to enjoy a mid-hike break and marvel at the beauty of Incan architecture.

Image courtesy of lenstherapy.wordpress.com

Sayacmarca: First discovered by the famous Hiram Bingham when he wandered along a road extending from Machu Picchu, the dramatic Sayacmarca is situated at a fork in an old Incan road in a dense subtropical forest full of butterflies and hummingbirds. Quechua for “Dominant Town,” these unique ruins have an almost mystical air about them and are arguably the most impressive along the Inca Trail (except for Machu Picchu itself, of course!). It is believed that Sayacmarca was actually built by the Colla, a major enemy of the Incas, and that the Incas took over the site following their conquest of the group.

Image courtesy of 4feet2mouths.com

Phuyupatamarca: Dubbed “La Ciudad entre la Niebla” (“The City above the Clouds”), this major archeological site is situated a staggering 3,200 meters above sea level. Apropos to the nickname, Phuyupatamarca is very often surrounded by dense, white clouds. The ruins, dramatically constructed into a steep cliffside, contain five stone baths that fill up with freshwater during the rainy season. It is believed that these baths were used for religious ceremonies. Visitors can also check out the site’s elaborate hydraulic system, a true testament to impressive capabilities of Incan engineering. Of all of the Incan ruins in the region, Phuyupatamarca is arguably the most intact and therefore a truly spectacular site for trekkers passing through.

"Phuyupatamarca (cloud-level town)" by D. Gordon E. Robertson - Own work. Licensed under CC BY-SA 3.0 via Wikimedia Commons.

Huiñay Huayna (Wiñay Wayna): Huiñay Huayna (traditionally spelled Wiñay Wayna in Quechua, the language of the Incas) was constructed into a steep hillside overlooking the Urubamba River. In addition to the site’s ancient houses and temples, it also boasts an incredibly complex system of Incan terraces, formerly used for agriculture. The name of the site roughly translates to “Forever Young,” and many trekkers report that these ruins are the most beautiful found along the trail.

Image courtesy of http://blog.teara.govt.nz

These are just some of what you will see along the Inca Trail: Learn more about popular Inca Trail itineraries here





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Saying goodbye through a screen: Family remembers COVID-19 victim at LTC home

Laurie Few knew their time with her father Allan was short when he tested positive for COVID-19 last Sunday.






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4 Thanksgiving Travel Tips to Save You Time

Filed under: , , ,

Associated Press

Sure, some of these travel tips are basic. But Thanksgiving travel is looking to be an even bigger mess than normal this year, especially around the East Coast. So this 90-second refresher from Samantha Brown and Mark "Hawkeye Louis" could save you hours.

Continue reading 4 Thanksgiving Travel Tips to Save You Time

4 Thanksgiving Travel Tips to Save You Time originally appeared on Gadling on Tue, 26 Nov 2013 11:30:00 EST. Please see our terms for use of feeds.

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Learn cybersecurity essentials on your own time at home with these classes

Fear is ripe soil for the unscrupulous. With so much uncertainty and concern over our health and the broader world economy, cybercriminals have been playing on that fear to steal a few extra dollars out of the most scared and vulnerable. The U.S. Secret Service warned that phishing attacks were up significantly and scams over fake COVID-19 treatments have led to seizures and arrests.

From companies and organizations to individuals, it’s never been more important for everyone to have their cybersecurity measures on high alert. And whether you’re looking to protect your own assets or you’ve been tasked with safeguarding a company and all its workers, the vital work of white hat hackers is absolutely essential these days.

The training in The Ultimate 2020 White Hat Hacker Certification Bundle can put you in a position to understand all aspects of maintaining cybersecurity for a communication system of virtually any size, a lucrative career that can earn you a six-figure income.

The four-part Complete Cyber Security Course (taught by cybersecurity expert and noted consultant Nathan House) is a 360-degree starting point for any cybersecurity career. Starting at the beginning, each part of this multi-pronged introduction will help guide you through vital knowledge, from network hacking techniques and vulnerability scanning to all the defense methods that assure every laptop, desktop, smartphone and tablet in your network remain secure.

The hacker training continues with the rest of the courses in the collection, including building security analysis tools using Python and learning how to analyze web app security vulnerabilities and solutions using frameworks like Ruby on Rails and PHP. Read the rest





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White House won't consider another stimulus bill in May -Kudlow

The White House has halted talks with Congress over any further coronavirus stimulus package as it waits for more information about how U.S. state reopenings affect the economy, White House top economic adviser Larry Kudlow told reporters on Friday. The Senate and House of Representatives have already passed four major bills to address the novel coronavirus outbreak, including three aimed at stabilizing the economy as most Americans have sheltered in place and unemployment has soared.





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Cell-specific expression of the transcriptional regulator RHAMM provides a timing mechanism that controls appropriate wound re-epithelialization [Glycobiology and Extracellular Matrices]

Prevention of aberrant cutaneous wound repair and appropriate regeneration of an intact and functional integument require the coordinated timing of fibroblast and keratinocyte migration. Here, we identified a mechanism whereby opposing cell-specific motogenic functions of a multifunctional intracellular and extracellular protein, the receptor for hyaluronan-mediated motility (RHAMM), coordinates fibroblast and keratinocyte migration speed and ensures appropriate timing of excisional wound closure. We found that, unlike in WT mice, in Rhamm-null mice, keratinocyte migration initiates prematurely in the excisional wounds, resulting in wounds that have re-surfaced before the formation of normal granulation tissue, leading to a defective epidermal architecture. We also noted aberrant keratinocyte and fibroblast migration in the Rhamm-null mice, indicating that RHAMM suppresses keratinocyte motility but increases fibroblast motility. This cell context–dependent effect resulted from cell-specific regulation of extracellular signal-regulated kinase 1/2 (ERK1/2) activation and expression of a RHAMM target gene encoding matrix metalloprotease 9 (MMP-9). In fibroblasts, RHAMM promoted ERK1/2 activation and MMP-9 expression, whereas in keratinocytes, RHAMM suppressed these activities. In keratinocytes, loss of RHAMM function or expression promoted epidermal growth factor receptor–regulated MMP-9 expression via ERK1/2, which resulted in cleavage of the ectodomain of the RHAMM partner protein CD44 and thereby increased keratinocyte motility. These results identify RHAMM as a key factor that integrates the timing of wound repair by controlling cell migration.




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Re: Covid-19: how to use your time when clinical placements are postponed - Wellbeing perspective




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First-time moms speak out

Simply put, motherhood is a beautiful thing. As one person puts it, all love begins and ends there. And though many who have had the opportunity to experience the beloved state boldly admit that it’s not always roses, the bottom line remains that...




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All at Sea: The Policy Challenges of Rescue, Interception, and Long-Term Response to Maritime Migration

With maritime migration the subject of significant policy and public focus in Europe, Australia, and beyond, this timely volume reviews the policy responses to irregular maritime arrivals at regional, national, and international levels. The book includes case studies of the major global hotspots—the Mediterranean, Gulf of Aden, Bay of Bengal/Andaman Sea, Australia, and the Caribbean—and examines trends and policy responses.




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Researchers develop non-invasive deep brain stimulation method

Researchers at MIT have developed a new method of electrically stimulating deep brain tissues without opening the skull

Since 1997, more than 100,000 Parkinson’s Disease patients have been treated with deep brain stimulation (DBS), a surgical technique that involves the implantation of ultra-thin wire electrodes. The implanted device, sometimes referred to as a ‘brain pacemaker’, delivers electrical pulses to a structure called the subthalamic nucleus, located near the centre of the brain, and effectively alleviates many of the physical symptoms of the disease, such as tremor, muscle rigidity, and slowed movements.

DBS is generally safe but, like any surgical procedure, comes with some risks. First and foremost, it is highly invasive, requiring small holes to be drilled in the patient’s skull, through which the electrodes are inserted. Potential complications of this include infection, stroke, and bleeding on the brain. The electrodes, which are implanted for long periods of time, sometimes move out of place; they can also cause swelling at the implantation site; and the wire connecting them to the battery, typically placed under the skin of the chest, can erode, all of which require additional surgical procedures.

Related: Blowing up the brain to reveal its finer details

Related: Traces of memory in a dish | Mo Costandi

Continue reading...