Le pr�sident malgache avec la d�l�gation bissau-guin�enne lors de la remise des dons de Covid-Organics, le 1er mai dernier. ......

Two men were arrested Friday in the fatal shooting of a security guard who demanded a woman wear a mask while shopping at a store.

1. Upcoming German Annual General Meetings season 2020 A lot of German corporates have traditionally lined up their annual general meetings (AGM) for May, June and July. In the wake of the co-rona virus crisis, the boards of a large number of compa...

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The Charities Act 2006 (now the Charities Act 2011) introduced a new form of incorporated charitable entity, the CIO.  There has been a long delay in making CIOs available but their imminent arrival has been heralded by a recent government anno...

Gerald Seib: “Michigan has nearly every ingredient going into the 2020 stew. It is a classic swing state that had been reliably Democratic blue in presidential politics until President Trump...

Following is the message President Recep Tayyip Erdoğan issued on Europe Day: 'Today is the 70th anniversary of the Schuman Declaration that gave life to the idea of the European Union (EU). Since the approval of Turkey's candidacy to the EU in 1999, the '9 May Europe Day' is celebrated in Turkey, together with the people of Europe. The ideas behind the Schuman Declaration have provided the resurrection of the Europe from its ashes following a war ruining the whole world. These ideas enabled the countries to come together for peace, security, development and prosperity by...

One of the major challenges posed by the rapid growth in the use of AI is whether or not existing IP systems are adequate to deal with the ownership and exploitation of AI-assisted and AI-generated products, processes, works and designs, which is so...

In the wake of the Covid-19 pandemic, there are no allocations for additional food relief

On Thursday, this newspaper reported that an inter-ministerial committee was to table before Cabinet a framework paper on a strict post-lockdown transport sector plan where public transport vehicles will face 42 days of extended lockdown in a bid to decongest the city. When approved, the new rules will compel passenger vehicles to be taken for inspection every after six months, at the owner’s cost, and there will be compulsory registration of all boda boda cyclists.

[Observer] President Yoweri Kaguta Museveni has cautioned the general public to always wear masks whenever they are out of their homes. The president said wearing mask will help combat the spread of the Coronavirus (COVID-19) and its infection to other people.

The diplomatic visit will be the first since Israel closed its borders to foreigners in light of the coronavirus pandemic.

As many as 44 million people in Africa could be infected with Covid-19 in the first year of the pandemic if containment measures fail – causing 83,000 to 190,000 deaths – according to modelling by the World Health Organisation, reflecting fears of a potential widening crisis on the continent.The study, released on Thursday by WHO Africa, looked at 47 countries with a combined population of 1 billion people and suggested smaller countries alongside Algeria, South Africa and Cameroon were at a…

The African Union (AU) said it has held discussions with officials from Madagascar to find out more about a herbal drink recently touted by the island nation’s president as a possible treatment for Covid-19.According to a statement issued on Tuesday, AU Commissioner for Social Affairs Amira El Fadil held a meeting with the chargé d’affaires of Madagascar’s embassy in the Ethiopian capital Addis Ababa on April 30, at which it was agreed that more information would be provided about the…

A serial litigant known for taking the Hong Kong government to court faces being declared bankrupt after the justice department filed a petition against him.Retired civil servant Kwok Cheuk-kin, dubbed the “king of judicial reviews” by the media, has been filing applications with the High Court since 2006, often challenging the legality of government policies and decisions.But many of his attempts ended in failure, and despite being ordered to bear the government’s legal costs in such…

Anand Gandhi revealed that before Irrfan Khan’s demise, he had been discussing a possible collaboration

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Michael Bay clarified that it wasn’t his decision to lay off Megan Fox

To reduce air pollution, national and city government policy makers, their development partners, academe, and the private sector need to work with young people. 

Criticising the Sindh government for “playing politics” over the holding of mourning religious congregations by issuing a notification to ban such congregations, the Majlis-e-Wahdat Muslimeen announced on Friday that the Yaum-e-Ali procession would be organised on Ramazan 21 after...

NEW DELHI: India’s top medical research body has turned down a proposal by the Modi government to test water from the Ganges river as a cure for coronavirus, ThePrint news portal said on Thursday.

It said the Indian Council of Medical Research (ICMR) turned down the government’s “request” to conduct research on a theory that Gangajal, or water from Ganges river, could possibly cure Covid-19.

Speaking to ThePrint, a source in the ICMR said the agency has refused to get involved as it is focussing on the Covid-19 battle and doesn’t want to waste time on other research amid the pandemic.

The move came after the country’s apex medical research body received a “request” from the Ministry of Jal Shakti to conduct “further research” on a proposal by an NGO, Atulya Ganga, said an ICMR official, who didn’t wish to be named.

In its letter last month, Mr Atulya had cited the presence of a “ninja virus”, called bacteriophage, in Ganges water that could cure Covid-19, the disease caused by the new coronavirus. Bacteriophage is a special type of virus that eats harmful bacteria, the letter said.

According ThePrint, the NGO asked the government on April 3 to conduct a study on the possibility of this virus acting as a cure. It sent a copy each to the ministry and the Prime Minister’s Office (PMO). The ministry’s National Mission for Clean Ganga, the department administering the Modi government’s ambitious Namami Gange programme, then wrote to ICMR on April 30 requesting a clinical trial.

The ICMR then held a meeting to discuss the idea, but refused to proceed, offering only its “help” to the NGO, ThePrint said. “We had indeed received a letter from the Ministry of Jal Shakti for such research. The experts at ICMR also held a meeting on this matter. Then we asked those proposing this research that you should tell us about hospitals and doctors that are ready and willing to conduct some research on it. We will certainly help them in this regard,” said the ICMR official.

“As of now we are still treating plasma therapy as a trial for treatment for corona (Covid-19), then how can we so quickly accept a virus called bacteriophage, found in the water of Ganges, as a cure? Right now, there is no logic in the argument that the virus found in Ganga’s water can indeed fight the coronavirus disease,” added the official.

However, he added that if the ministry takes an initiative into the matter then ICMR will extend its assistance to it.

Speaking to ThePrint, Dr Rajnikant Srivastava, ICMR’s head of the Department of Research Management, Policy Planning and Communication, in Delhi and Director of Regional Medical Research Centre, Gorakhpur, said: “A presentation was made after the Jal Shakti ministry’s proposal. The matter is at a very preliminary stage. Nothing has been decided on the future course of action. We will support the Jal Shakti ministry in all the work it does on this front.”

A senior official of the Ministry of Jal Shakti, meanwhile, said there are several special properties in the river and many people were demanding research on them.

Published in Dawn, May 8th, 2020

The project aimed to improve the transport conditions and services in Longnan municipality in the People's Republic of China. The targeted outcomes were the provision of efficient, safe and reliable road transport in the project area; and improved access to markets, income generating opportunities, education and health services and social activities for rural people. Key to this was a targeted reduction in travel times of between 5 and 7 hours, with 90% of the villages being served by an all-weather road.

Dentons is now the largest global law firm in Argentina and the first truly Pan-Latin American and the Caribbean firm in the history of the legal profession.

Proyek perbaikan kawasan kumuh: 670 ribu keluarga di Indonesia nikmati manfaat dari perbaikan akses air dan sanitasi.

MCHP to Present at JP Morgan Conference

The passage of contentious Telangana bill in the Lok Sabha may not have much impact on investment sentiment in realty sector across Hyderabad, as the city has already been planned to serve as a joint capital for next 10 years, according to property consultant Jones Lang LaSalle. “The Bill is being viewed with mixed feelings by various stakeholders, but it is still too early to gauge its impacts on the real estate industry. That said, it is likely to end the political uncertainty that Hyderabad has been facing for the past few years. “The outcomes are still unclear, but Brand Hyderabad is not likely to be overly affected as it […]

The remote Fijian island of Cicia has launched a novel business in organic produce that could prove to be a template for other developing communities around the world. The island declared itself chemical free and fully organic eight years ago and is now producing food that's attracting the interest of foreign buyers. Tara Cleary reports.

Since the discovery of Asgard archaea in 2015, evidence has mounted that these peculiar single-celled organisms could be the source of all complex life – including us

Earth’s continents may have been shifting for 2.5 billion years, according to a study of ancient rocks that finds plate tectonics evolved far earlier than we thought

HARMAN is excited and ready to head to Las Vegas in the New Year, once again, for the Consumer Electronics Show or CES. Without a doubt, CES is one of the most prominent and strategic events for the technology, automotive and the broader business...

Gene-edited pigs and brain implants are blurring the lines of what it means to be human, so our morals and laws may need to change to include beings that are “substantially human”

Millions of people will try a vegan diet this month for Veganuary. But can short-term or part-time vegans really reap health and environmental benefits? New Scientist put it to the test

Title: Health Tip: Understanding Organic Foods
Category: Health News
Created: 4/27/2010 8:10:00 AM
Last Editorial Review: 4/27/2010 12:00:00 AM

Title: Test Spots Potential Organ Donors Among Coma Patients
Category: Health News
Created: 4/26/2010 4:10:00 PM
Last Editorial Review: 4/27/2010 12:00:00 AM

Title: How Transplanted Livers Guard Against Organ Rejection
Category: Health News
Created: 4/27/2018 12:00:00 AM
Last Editorial Review: 4/30/2018 12:00:00 AM

Title: Pangolins Hold Clues to How COVID-19 Began -- and Might End
Category: Health News
Created: 5/8/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM

Learning more about this evolutionary advantage in pangolins may suggest possible treatments for coronavirus in humans, the team said.

The demand for transplantable solid organs far exceeds the supply of deceased donor organs. Patient selection criteria are determined by individual transplant programs; given the scarcity of solid organs for transplant, allocation to those most likely to benefit takes into consideration both medical and psychosocial factors. Children with intellectual and developmental disabilities have historically been excluded as potential recipients of organ transplants. When a transplant is likely to provide significant health benefits, denying a transplant to otherwise eligible children with disabilities may constitute illegal and unjustified discrimination. Children with intellectual and developmental disabilities should not be excluded from the potential pool of recipients and should be referred for evaluation as recipients of solid organ transplants.

Key Points

Key Points

Programmed death-ligand 1 (PD-L1/B7-H1) serves as a cosignaling molecule in cell-mediated immune responses and contributes to chronicity of inflammation and the escape of tumor cells from immunosurveillance. Here, we investigated the molecular mechanisms leading to PD-L1 upregulation in human oral carcinoma cells and in primary human gingival keratinocytes in response to infection with Porphyromonas gingivalis (P. gingivalis), a keystone pathogen for the development of periodontitis. The bacterial cell wall component peptidoglycan uses bacterial outer membrane vesicles to be taken up by cells. Internalized peptidoglycan triggers cytosolic receptors to induce PD-L1 expression in a myeloid differentiation primary response 88 (Myd88)-independent and receptor-interacting serine/threonine-protein kinase 2 (RIP2)-dependent fashion. Interference with the kinase activity of RIP2 or mitogen-activated protein (MAP) kinases interferes with inducible PD-L1 expression.

Active matter, both synthetic and biological, demonstrates complex spatiotemporal self-organization and the emergence of collective behavior. A coherent rotational motion, the vortex phase, is of great interest because of its ability to orchestrate well-organized motion of self-propelled particles over large distances. However, its generation without geometrical confinement has been a...

Functioning cells depend on the outward-facing plasma membrane (PM) effectively contacting the endoplasmic reticulum (ER), which serves as a central hub for contacts with mitochondria and other intracellular organelles. The contact sites are critical to intracellular communication because they mediate intermembrane exchange of lipids, ions, and other small molecules that...

Kathryn Knight

Background

Mutations in CTNS—a gene encoding the cystine transporter cystinosin—cause the rare, autosomal, recessive, lysosomal-storage disease cystinosis. Research has also implicated cystinosin in modulating the mTORC1 pathway, which serves as a core regulator of cellular metabolism, proliferation, survival, and autophagy. In its severest form, cystinosis is characterized by cystine accumulation, renal proximal tubule dysfunction, and kidney failure. Because treatment with the cystine-depleting drug cysteamine only slows disease progression, there is an urgent need for better treatments.

Background

The utility of kidney organoids in regenerative medicine will rely on the functionality of the glomerular and tubular structures in these tissues. Recent studies have demonstrated the vascularization and subsequent maturation of human pluripotent stem cell–derived kidney organoids after renal subcapsular transplantation. This raises the question of whether the glomeruli also become functional upon transplantation.