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Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline


Tuesday, October 22, 2024 Dr. Emily Freeman

Dr. John Blake is a research engineer at Canadian Blood Services and a Professor in the Department of Industrial Engineering at Dalhousie University. Based in Halifax, Nova Scotia, Dr. Blake and his trainees use engineering principles and various computer-based optimization techniques to inform large scale decisions at Canadian Blood Services.  

Applying network modelling to biologics  

To some, it may be surprising to learn that there is such opportunity to integrate engineering into the health-care focused setting of Canadian Blood Services. However, as Dr. Blake explains, the same engineering principles that apply to the development and quality assurance of other products also apply to biologics such as blood, stem cells and organs. One of these classic engineering approaches currently applied to improving operations at Canadian Blood Services is network modelling.  

Network modelling is a computer-based method that creates a virtual representation of objects and their relation to each other. The resulting models are particularly useful for maintaining adaptability in the collection of blood donations, as well as the distribution and inventory management strategies that allow Canadian Blood Services to remain a safe and reliable provider of life-saving products. 

Dr. Blake making friends while walking the Camino de Santiago in Spain

Contributing to efficiency and sustainability in Canada’s Lifeline  

For Dr. Blake’s team, modelling is not about the data acquired but rather how they can turn existing data into real life change. Part of this approach is ensuring that Canadian Blood Services is asking the right questions when it comes to allocating resources. For example, Dr. Blake has worked on models to assess how changing stem cell donor recruitment will affect the number of matches for Canadian patients. By modelling things such as recruitment approaches, Dr. Blake’s work assists Canadian Blood Services to consistently identify ways to improve Canada’s Lifeline.

Recently, Dr. Blake has also been applying this method to optimize the number and location of mobile and permanent donor facilities across the nation. This redesign of the donation facility network will address the growing demand for donations by bringing Canadian Blood Services’ facilities closer to the donors. 

“I have waited my entire career for a problem of this type – it is truly a once in a lifetime opportunity.”

Dr. John Blake, Canadian Blood Services Research Engineer

Securing the future of Canada’s Lifeline  

To sustain a safe and effective blood system in Canada for years to come, network modelling and optimization is a never-ending process. This is one of the reasons that Dr. Blake is committed to securing the future of transfusion and transplantation systems by training and mentoring the next generation of engineers. In fact, seeing his former students join Canadian Blood Services and dedicate their talents to improving the future of Canada’s Lifeline is one of Dr. Blake’s proudest achievements.  

One of Dr. Blake’s former students, Matt Nelson, is now an industrial engineer at Canadian Blood Services.  

“In my role, I use systematic thinking to build and run complex models; collect and analyze the required data; produce useful results; and explain these results to non-technical leaders on a regular basis,” Matt says. Recently, Matt contributed to the launch and expansion of pathogen-reduced platelets, a new product that was implemented across Canadian Blood Services production sites starting in 2022. The implementation of pathogen-reduced platelets has provided an additional layer of safety for recipients by reducing the risk of potential transfusion-transmitted pathogens without compromising the quality of the component. Matt credited Dr. Blake in helping him develop the necessary skills he now dedicates to safeguarding Canada’s Lifeline:  

“Dr. Blake was the professor who introduced me to the uses of simulation to understand complex non-linear systems. This type of system is very common in situations that have a lot of variability – like the blood system – and simulation allows for exploration of the response of the system to changes.” 

Matt Nelson, Canadian Blood Services Industrial Engineer

Over the years, Dr. Blake’s ongoing modelling work and mentorship activities have also led to many recognitions and awards, but he is most proud of being recognized as Professor of the Year by Dalhousie Undergraduate students, and with awards for his contributions to the Canadian Operational Research Society. He has even the earned the distinction of being Dalhousie’s first engineer to be awarded grant funding from the tri-council agency, Social Sciences and Humanities Research Council (SSHRC). 

“I am proud to work on projects that have a measurable impact on people’s health and well-being,” Dr. Blake says. “I am forever grateful to Dr. Dana Devine for first giving me the opportunity to serve Canadians in this role at Canadian Blood Services.” 


Canadian Blood Services – Driving world-class innovation

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency.  

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This post was written by Marie-Soleil Smith, PhD Candidate in Dr. Hélène Côté’s Lab at the University of British Columbia, and edited by Dr. Geraldine Walsh, knowledge broker at Canadian Blood Services. It originally appeared on the Centre for Blood Research blog in March 2022.


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For the latest instalment of “Meet the researcher” we chatted with Dr. John Blake, Canadian Blood Services’ research engineer and also known as “the numbers guy”.


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Re: etiquette for replying to daily digests

Posted by Suresh Ramasubramanian on Nov 08

Does nanog have a mime digest format so you get one big email with all the emails of the day attached as separate eml?
Then all you do is select just the particular email you want to reply to and there you are.

--srs
________________________________
From: NANOG <nanog-bounces+ops.lists=gmail.com () nanog org> on behalf of joel () joelesler net <joel () joelesler net>
Sent: Saturday, November 9, 2024 1:08:41 AM
To: Alex Buie...




ue

Re: etiquette for replying to daily digests

Posted by Alex Buie on Nov 08

Appreciate all the input everyone! It's helpful

Suresh - great pointer - it looks like they do. I didn't even notice it as
an option. I think this will be the fastest/easiest method for me in
webmail-land. Thanks for pointing that out!

*Alex Buie*Senior Cloud Operations Engineer

450 Century Pkwy # 100 Allen, TX 75013
<https://maps.google.com/?q=450+Century+Pkwy+STE+100+%7C+Allen,+TX+%7C+75013&entry=gmail&source=g>
D:...




ue

Re: etiquette for replying to daily digests

Posted by Suresh Ramasubramanian on Nov 08

It’s been decades since the last time I used this option.. and that was on an actual listserv run on lsoft.com, early
2000s.

These days just subscribed from a gmail because threaded posts, keyboard shortcuts for email actions and what not.
Makes it very easy to handle high traffic mailing lists.

--srs
________________________________
From: Alex Buie <abuie () cytracom com>
Sent: Saturday, November 9, 2024 8:21:36 AM
To: Suresh...




ue

Re: etiquette for replying to daily digests

Posted by Willy Manga on Nov 09

Hi,

1. I locate the relevant message I want to reply

2. Delete everything before/after or with some mail client (like
Thunderbird) , I can just select the message and hit the 'reply' button.
It will include only the selected text

2. Copy exactly the subject line of the relevant message I want to reply
and if it doesn't yet contain a 'Re:' in front, I insert it.

And that is exactly what I'm doing with this...




ue

Re: etiquette for replying to daily digests

Posted by Bjørn Bürger via NANOG on Nov 11

Am 8. November 2024 20:14:34 MEZ schrieb Alex Buie <abuie () cytracom com>:

Speaking for myself:

- If possible, change your digest mode from text to MIME in your personal setting dialog of the mailman interface. This
leaves all relevant headers intact and you can directly reply to each individual message, preserving correct threading.
However, be aware, that some MUAs don't support this.

- If you need to stick with text digest,...




ue

Re: etiquette for replying to daily digests

Posted by Jay Acuna on Nov 11

On Sat, Nov 9, 2024 at 4:46 AM Suresh Ramasubramanian <ops.lists () gmail com>
wrote:

Yes.. Digest modes are generally unsuitable for active participation in a
mailing list.

I think the entire purpose of Digest mode is to minimize traffic for users
who are interested
solely in skimming through everything that was written days or weeks after
discussion
took place. You would not have any good or convenient way to pick an item
out of
a...




ue

Re: etiquette for replying to daily digests

Posted by Mike Hammett on Nov 11

I use dedicated email addresses for each mailing list that I'm on so that I can file accordingly and thus, don't need
to use digests.

-----
Mike Hammett
Intelligent Computing Solutions

Midwest Internet Exchange

The Brothers WISP

----- Original Message -----

From: "Alex Buie" <abuie () cytracom com>
To: nanog () nanog org
Sent: Friday, November 8, 2024 1:14:34 PM
Subject: etiquette for replying to daily...




ue

Re: etiquette for replying to daily digests

Posted by nanog on Nov 11

FWIW this did appear as a new thread in my client (Thunderbird).

Replying to the digest like this breaks the proper reply link in the
message headers, and relies on clients using heuristics like matching
the subject and quoted text, which not all clients will do.




ue

Re: etiquette for replying to daily digests

Posted by Tom Beecher on Nov 11

1. As others have said, digests generally don't work well for lists you
want to actively participate in.
2. No matter which methods or suggestions provided you may chose, there is
a 100% chance someone will gripe about how it breaks in their chosen mail
client , or messes with their personal email flow. So do what makes sense
to you and let the chips fall where they will. :)




ue

etiquette for replying to daily digests

Posted by Matthew Petach on Nov 11

Isn't it better to *not* put the "Re: " in the subject line, so that the
reply
keeps the same threading as the original message?

Or am I just an outlier in doing it without the "Re: " addition in the
subject line?

Matt




ue

Re: etiquette for replying to daily digests

Posted by William Herrin on Nov 11

Doesn't matter. Without the headers most MUAs don't thread it. In the
case of Willy's message, the header:

In-Reply-To: <mailman.1.1731153601.10419.nanog () nanog org>

Caused my MUA to attempt to thread it with a digest message I never
received, hence it started a new thread.

Subject change is _usually_ used the other way: to recognize that a
change beyond adding "Re: " means that the thread has branched....




ue

Re: etiquette for replying to daily digests

Posted by Bryan Fields on Nov 12

The digest is a standard mailman 2.1 digest, which means you will get a MIME
email with multipart/mixed. The first part will be the topics listed and then
each part after that will be an individual message.

The easiest way to reply to this is to go into the individual message and open
it then reply. Most MUAs will include the right headers.

I've not messed with digests on NANOG in close to 5/6 years, but this was one
of the things I...




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Re: etiquette for replying to daily digests

Posted by Chris Hills on Nov 13

Another option is to locate the message with a usenet/newsgroup/nntp
client at nntp://news.gmane.io/gmane.org.operators.nanog and reply from
there.

Best from brsk,

@|from|name|@
@|from|title|@
E @|from|email|@

Disclaimer

The information contained in this communication from the sender is confidential. It is intended solely for use by the
recipient and others authorized to receive it. If you are not the recipient, you are hereby notified...




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